DRUG BINDING INTERFACES MAPPED TO 'GERANYLGERANYL PYROPHOSPHATE SYNTHASE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
6G31_A_ZOLA401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
7 ASP A  64
ASP A  68
ARG A  73
GLN A 126
LYS A 151
GLN A 185
LYS A 212
ZOL A 401
6G31_B_ZOLB401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 6 ASP B  64
ASP B  68
ARG B  73
GLN B 126
LYS B 151
GLN B 185
ZOL B 401
6G31_C_ZOLC401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 5 ASP C  64
ASP C  68
ARG C  73
GLN C 126
LYS C 151
ZOL C 401
6G31_D_ZOLD401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 7 LEU D  61
ASP D  64
ASP D  68
ARG D  73
GLN D 126
LYS D 151
GLN D 185
ZOL D 401
6G31_E_ZOLE401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 4 LEU E  61
ASP E  64
ASP E  68
ARG E  73
ZOL E 401
6G31_F_ZOLF401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 5 ASP F  64
ASP F  68
ARG F  73
GLN F 126
GLN F 185
ZOL F 401
6G31_G_ZOLG401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 7 ASP G  64
ASP G  68
ARG G  73
GLN G 126
LYS G 151
GLN G 185
TYR G 188
ZOL G 401
6G31_H_ZOLH401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 5 ASP H  64
ASP H  68
GLN H 126
GLN H 185
LYS H 212
ZOL H 401
6G31_I_ZOLI401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 4 ASP I  64
ASP I  68
LYS I 151
GLN I 185
ZOL I 401
6G31_J_ZOLJ401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 6 LEU J  61
ASP J  64
ASP J  68
ARG J  73
GLN J 126
GLN J 185
ZOL J 401
6G31_K_ZOLK401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 4 ASP K  64
ASP K  68
ARG K  73
GLN K 126
ZOL K 401
6G31_L_ZOLL401 6g31 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE
None 6 ASP L  64
ASP L  68
ARG L  73
GLN L 126
GLN L 185
LYS L 212
ZOL L 401