DRUG BINDING INTERFACES MAPPED TO 'GENOME POLYPROTEIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2PXC_A_SAMA500 | 2pxc | SAM DB00118(S-Adenosylmethionine) | Murray Valleyencephalitisvirus | GENOME POLYPROTEIN[CONTAINS: CAPSIDPROTEIN C (COREPROTEIN); ENVELOPE PROTEIN M(MATRIX PROTEIN); MAJOR ENVELOPEPROTEIN E; NON-STRUCTURALPROTEIN 1 (NS1); NON-STRUCTURALPROTEIN 2A (NS2A); FLAVIVIRIN PROTEASENS2B REGULATORYSUBUNIT; FLAVIVIRIN PROTEASENS3 CATALYTICSUBUNIT; NON-STRUCTURALPROTEIN 4A (NS4A); NON-STRUCTURALPROTEIN 4B (NS4B); RNA-DIRECTED RNAPOLYMERASE (EC2.7.7.48) (NS5)] | PF01728(FtsJ) | 14 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 500 |
3KEE_A_30BA500 | 3kee | 30B DB06290(Simeprevir) | Hepacivirus C | GENOME POLYPROTEIN | PF02907(Peptidase_S29) | 16 | GLN A 41PHE A 43TYR A 56HIS A 57GLY A 58ASP A 81VAL A 132LYS A 136GLY A 137SER A 139PHE A 154ARG A 155ALA A 156ALA A 157CYS A 159ASP A 168 | 30B A 500 |
3KEE_B_30BB500 | 3kee | 30B DB06290(Simeprevir) | Hepacivirus C | GENOME POLYPROTEIN | no annotation | 15 | GLN B 41PHE B 43TYR B 56HIS B 57GLY B 58ASP B 81VAL B 132LEU B 135LYS B 136GLY B 137SER B 139PHE B 154ARG B 155ALA B 156ALA B 157 | 30B B 500 |
3KEE_C_30BC500 | 3kee | 30B DB06290(Simeprevir) | Hepacivirus C | GENOME POLYPROTEIN | no annotation | 16 | GLN C 41PHE C 43TYR C 56HIS C 57GLY C 58ASP C 81VAL C 132LEU C 135LYS C 136GLY C 137SER C 139PHE C 154ARG C 155ALA C 156ALA C 157ASP C 168 | 30B C 500 |
3KEE_D_30BD500 | 3kee | 30B DB06290(Simeprevir) | Hepacivirus C | GENOME POLYPROTEIN | no annotation | 16 | GLN D 41PHE D 43TYR D 56HIS D 57GLY D 58ASP D 81VAL D 132LEU D 135LYS D 136GLY D 137SER D 139PHE D 154ARG D 155ALA D 156ALA D 157ASP D 168 | 30B D 500 |
5E9Q_A_SAMA301 | 5e9q | SAM DB00118(S-Adenosylmethionine) | Dengue virus | GENOME POLYPROTEIN | PF01728(FtsJ) | 14 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 301 |
5E9Q_C_SAMC4000 | 5e9q | SAM DB00118(S-Adenosylmethionine) | Dengue virus | GENOME POLYPROTEIN | None | 14 | SER C 56GLY C 58GLY C 81GLY C 83GLY C 86TRP C 87THR C 104LYS C 105HIS C 110GLU C 111ASP C 131VAL C 132ASP C 146ILE C 147 | SAM C4000 |
5EC8_A_SAMA301 | 5ec8 | SAM DB00118(S-Adenosylmethionine) | Dengue virus | GENOME POLYPROTEIN | PF01728(FtsJ) | 14 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 301 |
5EC8_C_SAMC4000 | 5ec8 | SAM DB00118(S-Adenosylmethionine) | Dengue virus | GENOME POLYPROTEIN | None | 14 | SER C 56GLY C 58GLY C 81GLY C 83GLY C 86TRP C 87THR C 104LYS C 105HIS C 110GLU C 111ASP C 131VAL C 132ASP C 146ILE C 147 | SAM C4000 |
5EIF_A_SAMA301 | 5eif | SAM DB00118(S-Adenosylmethionine) | Dengue virus | GENOME POLYPROTEIN | PF01728(FtsJ) | 14 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110GLU A 111ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 301 |
5EIF_C_SAMC4000 | 5eif | SAM DB00118(S-Adenosylmethionine) | Dengue virus | GENOME POLYPROTEIN | None | 14 | SER C 56GLY C 58GLY C 81GLY C 83GLY C 86TRP C 87THR C 104LYS C 105HIS C 110GLU C 111ASP C 131VAL C 132ASP C 146ILE C 147 | SAM C4000 |
5KQS_A_SAMA307 | 5kqs | SAM DB00118(S-Adenosylmethionine) | Zika virus | GENOME POLYPROTEIN | PF01728(FtsJ) | 13 | SER A 56GLY A 58GLY A 81GLY A 83GLY A 86TRP A 87THR A 104LYS A 105HIS A 110ASP A 131VAL A 132ASP A 146ILE A 147 | SAM A 307 |
5MFX_A_ACTA701 | 5mfx | ACT DB03166(Aceticacid) | Zika virus | GENOME POLYPROTEIN | PF00271(Flavi_DEAD)PF07652(Helicase_C) | 5 | ARG A 323THR A 449HIS A 450ALA A 478ASP A 481 | ACT A 701 |