DRUG BINDING INTERFACES MAPPED TO 'GAG-POL POLYPROTEIN'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
2B60_B_RITB100 | 2b60 | RIT DB00503(Ritonavir) | Humanimmunodeficiencyvirus 1 | GAG-POL POLYPROTEIN | PF00077(RVP)no annotation | 23 | ARG B 8ARG A 8ASP A 25ASP B 25GLY A 27GLY B 27ALA B 28ALA A 28ASP A 29ASP B 29ILE B 32ILE A 32ILE A 47GLY A 49GLY B 49ILE B 50ILE A 50PRO B 81PRO A 81ALA B 82ALA A 82ILE A 84ILE B 84 | RIT B 100 |
3JVY_B_017B401 | 3jvy | 017 DB01264(Darunavir) | Humanimmunodeficiencyvirus 1 | GAG-POL POLYPROTEIN | PF00077(RVP)no annotation | 26 | LEU A 23ASP A 25GLY A 27ALA A 28ASP A 29ASP A 30VAL A 32GLY A 49ILE A 50PRO A 81VAL A 82ILE A 84ARG B 108LEU B 123ASP B 125GLY B 127ALA B 128ASP B 129ASP B 130VAL B 132ILE B 147GLY B 149ILE B 150PRO B 181VAL B 182ILE B 184 | 017 B 401 |
3JW2_A_017A401 | 3jw2 | 017 DB01264(Darunavir) | Humanimmunodeficiencyvirus 1 | GAG-POL POLYPROTEIN | PF00077(RVP)no annotation | 26 | ARG A 8LEU A 23ASP A 25GLY A 27ALA A 28ASP A 29ASP A 30VAL A 32GLY A 49ILE A 50PRO A 81VAL A 82ILE A 84LEU B 123ASP B 125GLY B 127ALA B 128ASP B 129ASP B 130VAL B 132ILE B 147GLY B 149ILE B 150PRO B 181VAL B 182ILE B 184 | 017 A 401 |
4IFV_A_T27A601 | 4ifv | T27 DB08864(Rilpivirine) | Humanimmunodeficiencyvirus 1 | EXORIBONUCLEASE H,P66 RT;GAG-POL POLYPROTEIN | PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 14 | PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234PRO A 236TYR A 318 | T27 A 601 |
6ELI_A_T27A701 | 6eli | T27 DB08864(Rilpivirine) | Humanimmunodeficiencyvirus 1 | GAG-POL POLYPROTEIN;REVERSETRANSCRIPTASE | no annotation | 13 | PRO A 95LEU A 100LYS A 103VAL A 106GLU B 138VAL A 179TYR A 181TYR A 188PRO A 225PHE A 227TRP A 229LEU A 234TYR A 318 | T27 A 701 |