DRUG BINDING INTERFACES MAPPED TO 'FIBROBLAST GROWTH FACTOR RECEPTOR 1'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
4V01_A_0LIA1776 | 4v01 | 0LI DB08901(Ponatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B | PF07714(Pkinase_Tyr) | 21 | LEU A 484VAL A 492ALA A 512LYS A 514GLU A 531MET A 534MET A 535ILE A 538ILE A 545VAL A 561TYR A 563ALA A 564LEU A 614CYS A 619HIS A 621ARG A 622LEU A 630ILE A 639ALA A 640ASP A 641PHE A 642 | 0LI A1776 |
4V01_B_0LIB1770 | 4v01 | 0LI DB08901(Ponatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B | no annotation | 21 | LEU B 484VAL B 492ALA B 512LYS B 514GLU B 531MET B 534MET B 535ILE B 538ILE B 545VAL B 561TYR B 563ALA B 564LEU B 614CYS B 619HIS B 621ARG B 622LEU B 630ILE B 639ALA B 640ASP B 641PHE B 642 | 0LI B1770 |
4V04_A_0LIA1772 | 4v04 | 0LI DB08901(Ponatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B | PF07714(Pkinase_Tyr) | 20 | VAL A 492ALA A 512LYS A 514GLU A 531MET A 534MET A 535ILE A 545VAL A 561TYR A 563ALA A 564LEU A 614CYS A 619HIS A 621ARG A 622LEU A 630ILE A 639ALA A 640ASP A 641PHE A 642GLY A 643 | 0LI A1772 |
4V04_B_0LIB1771 | 4v04 | 0LI DB08901(Ponatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B | no annotation | 22 | LEU B 484VAL B 492ALA B 512LYS B 514GLU B 531MET B 534MET B 535ILE B 545VAL B 561TYR B 563ALA B 564LEU B 614CYS B 619HIS B 621ARG B 622LEU B 630ILE B 639ALA B 640ASP B 641PHE B 642GLY B 643LEU B 644 | 0LI B1771 |
5ZV2_A_LEVA801 | 5zv2 | LEV DB09078(Lenvatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1 | no annotation | 15 | LEU A 484GLY A 485PHE A 489VAL A 492ALA A 512LYS A 514GLU A 531MET A 535VAL A 561TYR A 563ALA A 564GLY A 567LEU A 630ALA A 640ASP A 641 | LEV A 801 |
5ZV2_B_LEVB801 | 5zv2 | LEV DB09078(Lenvatinib) | Homo sapiens | FIBROBLAST GROWTHFACTOR RECEPTOR 1 | no annotation | 15 | LEU B 484GLY B 485PHE B 489VAL B 492ALA B 512LYS B 514GLU B 531MET B 535VAL B 561TYR B 563ALA B 564GLY B 567LEU B 630ALA B 640ASP B 641 | LEV B 801 |