DRUG BINDING INTERFACES MAPPED TO 'FARNESYL PYROPHOSPHATE SYNTHASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1YHL_A_RISA1400 | 1yhl | RIS DB00884(Risedronate) | Trypanosoma cruzi | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 11 | LEU A 95ASP A 98ASP A 102ARG A 107GLN A 167LYS A 207THR A 208TYR A 211GLN A 247ASP A 250LYS A 264 | RIS A1400 |
2O1O_A_RISA400 | 2o1o | RIS DB00884(Risedronate) | Cryptosporidiumparvum | PUTATIVE FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | LEU A 112ASP A 115ASP A 119ARG A 124GLN A 184LYS A 210THR A 211GLN A 251ASN A 254 | RIS A 400 |
2O1O_B_RISB400 | 2o1o | RIS DB00884(Risedronate) | Cryptosporidiumparvum | PUTATIVE FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 10 | LEU B 112ASP B 115ASP B 119ARG B 124GLN B 184LYS B 210THR B 211GLN B 251ASN B 254LYS B 273 | RIS B 400 |
2Q58_A_ZOLA1 | 2q58 | ZOL DB00399(Zoledronicacid) | Cryptosporidiumparvum | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A1112ASP A1115ASP A1119ARG A1124GLN A1184LYS A1210THR A1211GLN A1251ASN A1254ASP A1255 | ZOL A 1 |
2Q58_B_ZOLB2 | 2q58 | ZOL DB00399(Zoledronicacid) | Cryptosporidiumparvum | FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 9 | ASP B2115ASP B2119ARG B2124GLN B2184LYS B2210THR B2211GLN B2251ASN B2254LYS B2273 | ZOL B 2 |
3EZ3_A_ZOLA397 | 3ez3 | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE, PUTATIVE | PF00348(polyprenyl_synt) | 9 | ASP A 126ASP A 130ARG A 135GLN A 195LYS A 243THR A 244GLN A 284ASP A 287LYS A 301 | ZOL A 397 |
3EZ3_B_ZOLB397 | 3ez3 | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE, PUTATIVE | no annotation | 9 | ASP B 126ASP B 130ARG B 135GLN B 195LYS B 243THR B 244GLN B 284ASP B 287LYS B 301 | ZOL B 397 |
3EZ3_C_ZOLC397 | 3ez3 | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE, PUTATIVE | no annotation | 9 | ASP C 126ASP C 130ARG C 135GLN C 195LYS C 243THR C 244GLN C 284ASP C 287LYS C 301 | ZOL C 397 |
3EZ3_D_ZOLD397 | 3ez3 | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE, PUTATIVE | no annotation | 10 | LEU D 123ASP D 126ASP D 130ARG D 135GLN D 195LYS D 243THR D 244GLN D 284ASP D 287LYS D 301 | ZOL D 397 |
3IBA_A_ZOLA901 | 3iba | ZOL DB00399(Zoledronicacid) | Trypanosoma cruzi | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | ASP A 98ASP A 102ARG A 107GLN A 167LYS A 207THR A 208TYR A 211GLN A 247ASP A 250LYS A 264 | ZOL A 901 |
3LDW_A_ZOLA397 | 3ldw | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | ASP A 126ASP A 130ARG A 135GLN A 195LYS A 243THR A 244GLN A 284ASP A 287LYS A 301 | ZOL A 397 |
3LDW_B_ZOLB397 | 3ldw | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 9 | ASP B 126ASP B 130ARG B 135GLN B 195LYS B 243THR B 244GLN B 284ASP B 287LYS B 301 | ZOL B 397 |
3LDW_C_ZOLC397 | 3ldw | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 9 | ASP C 126ASP C 130ARG C 135GLN C 195LYS C 243THR C 244GLN C 284ASP C 287LYS C 301 | ZOL C 397 |
3LDW_D_ZOLD397 | 3ldw | ZOL DB00399(Zoledronicacid) | Plasmodium vivax | FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 9 | ASP D 126ASP D 130ARG D 135GLN D 195LYS D 243THR D 244GLN D 284ASP D 287LYS D 301 | ZOL D 397 |
3N45_F_ZOLF354 | 3n45 | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 11 | LEU F 100ASP F 103ASP F 107ARG F 112GLN F 171LYS F 200THR F 201TYR F 204GLN F 240ASP F 243LYS F 257 | ZOL F 354 |
3N46_F_ZOLF354 | 3n46 | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU F 100ASP F 103ASP F 107ARG F 112GLN F 171LYS F 200THR F 201GLN F 240ASP F 243LYS F 257 | ZOL F 354 |
4KFA_A_ZOLA404 | 4kfa | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200GLN A 240ASP A 243LYS A 257 | ZOL A 404 |
4KPD_A_RISA405 | 4kpd | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | RIS A 405 |
4KPJ_A_210A901 | 4kpj | 210 DB00282(Pamidronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | LEU A 100ASP A 103ASP A 107ARG A 112LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | 210 A 901 |
4KQ5_A_ZOLA404 | 4kq5 | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | ZOL A 404 |
4KQS_A_RISA405 | 4kqs | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | RIS A 405 |
4N9U_A_RISA404 | 4n9u | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112THR A 167GLN A 171THR A 201GLN A 240ASP A 243LYS A 257 | RIS A 404 |
4NG6_A_RISA405 | 4ng6 | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 12 | LEU A 100ASP A 103ASP A 107ARG A 112THR A 167GLN A 171LEU A 200THR A 201TYR A 204GLN A 240ASP A 243LYS A 257 | RIS A 405 |
4NKE_A_RISA404 | 4nke | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | RIS A 404 |
4NKF_A_210A404 | 4nkf | 210 DB00282(Pamidronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | LEU A 100ASP A 103ASP A 107ARG A 112LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | 210 A 404 |
4NUA_A_RISA901 | 4nua | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | RIS A 901 |
4OGU_A_210A405 | 4ogu | 210 DB00282(Pamidronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | LEU A 100ASP A 103ASP A 107ARG A 112LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | 210 A 405 |
4P0V_A_ZOLA401 | 4p0v | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | ZOL A 401 |
4P0W_A_ZOLA501 | 4p0w | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 11 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200THR A 201TYR A 204GLN A 240ASP A 243LYS A 257 | ZOL A 501 |
4Q23_A_RISA901 | 4q23 | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 171LYS A 200TYR A 204GLN A 240ASP A 243LYS A 257 | RIS A 901 |
4RXD_A_RISA1404 | 4rxd | RIS DB00884(Risedronate) | Trypanosomabrucei | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU A 100ASP A 103ASP A 107ARG A 112GLN A 172LYS A 212THR A 213GLN A 252ASP A 255LYS A 269 | RIS A1404 |
4RXD_B_RISB1504 | 4rxd | RIS DB00884(Risedronate) | Trypanosomabrucei | FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 10 | LEU B 100ASP B 103ASP B 107ARG B 112GLN B 172LYS B 212THR B 213GLN B 252ASP B 255LYS B 269 | RIS B1504 |
4RXD_C_RISC1600 | 4rxd | RIS DB00884(Risedronate) | Trypanosomabrucei | FARNESYLPYROPHOSPHATESYNTHASE | no annotation | 10 | LEU C 100ASP C 103ASP C 107ARG C 112GLN C 172LYS C 212THR C 213GLN C 252ASP C 255LYS C 269 | RIS C1600 |
5CG5_A_RISA400 | 5cg5 | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 13 | PHE A 99LEU A 100ASP A 103ASP A 107ARG A 112THR A 167GLN A 171LYS A 200THR A 201TYR A 204GLN A 240ASP A 243LYS A 257 | RIS A 400 |
5CG6_A_RISA404 | 5cg6 | RIS DB00884(Risedronate) | Homo sapiens | FARNESYLPYROPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 12 | PHE A 99LEU A 100ASP A 103ASP A 107ARG A 112THR A 167GLN A 171LYS A 200THR A 201GLN A 240ASP A 243LYS A 257 | RIS A 404 |