DRUG BINDING INTERFACES MAPPED TO 'FARNESYL DIPHOSPHATE SYNTHASE'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1ZW5_A_ZOLA901 1zw5 ZOL

DB00399
(Zoledronic
acid)
Homo sapiens FARNESYL DIPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
9 ASP A 117
ASP A 121
ARG A 126
GLN A 185
LYS A 214
THR A 215
GLN A 254
ASP A 257
LYS A 271
ZOL A 901
2F89_F_210F9001 2f89 210

DB00282
(Pamidronate)
Homo sapiens FARNESYL DIPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
9 ASP F 103
ASP F 107
ARG F 112
LYS F 200
THR F 201
TYR F 204
GLN F 240
ASP F 243
LYS F 257
210 F9001
2F8C_F_ZOLF9001 2f8c ZOL

DB00399
(Zoledronic
acid)
Homo sapiens FARNESYL DIPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
11 LEU F 100
ASP F 103
ASP F 107
ARG F 112
GLN F 171
LYS F 200
THR F 201
TYR F 204
GLN F 240
ASP F 243
LYS F 257
ZOL F9001
2F8Z_F_ZOLF5001 2f8z ZOL

DB00399
(Zoledronic
acid)
Homo sapiens FARNESYL DIPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
10 LEU F 100
ASP F 103
ASP F 107
ARG F 112
GLN F 171
LYS F 200
THR F 201
GLN F 240
ASP F 243
LYS F 257
ZOL F5001
2F94_F_BFQF9001 2f94 BFQ

DB00710
(Ibandronate)
Homo sapiens FARNESYL DIPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
13 PHE F  99
LEU F 100
ASP F 103
ASP F 107
ARG F 112
THR F 167
GLN F 171
LYS F 200
THR F 201
TYR F 204
GLN F 240
ASP F 243
LYS F 257
BFQ F9001
2F9K_F_ZOLF9001 2f9k ZOL

DB00399
(Zoledronic
acid)
Homo sapiens FARNESYL DIPHOSPHATE
SYNTHASE
PF00348
(polyprenyl_synt)
10 LEU F 100
ASP F 103
ASP F 107
ARG F 112
GLN F 171
LYS F 200
THR F 201
GLN F 240
ASP F 243
LYS F 257
ZOL F9001