DRUG BINDING INTERFACES MAPPED TO 'FARNESYL DIPHOSPHATE SYNTHASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1ZW5_A_ZOLA901 | 1zw5 | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYL DIPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | ASP A 117ASP A 121ARG A 126GLN A 185LYS A 214THR A 215GLN A 254ASP A 257LYS A 271 | ZOL A 901 |
2F89_F_210F9001 | 2f89 | 210 DB00282(Pamidronate) | Homo sapiens | FARNESYL DIPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 9 | ASP F 103ASP F 107ARG F 112LYS F 200THR F 201TYR F 204GLN F 240ASP F 243LYS F 257 | 210 F9001 |
2F8C_F_ZOLF9001 | 2f8c | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYL DIPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 11 | LEU F 100ASP F 103ASP F 107ARG F 112GLN F 171LYS F 200THR F 201TYR F 204GLN F 240ASP F 243LYS F 257 | ZOL F9001 |
2F8Z_F_ZOLF5001 | 2f8z | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYL DIPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU F 100ASP F 103ASP F 107ARG F 112GLN F 171LYS F 200THR F 201GLN F 240ASP F 243LYS F 257 | ZOL F5001 |
2F94_F_BFQF9001 | 2f94 | BFQ DB00710(Ibandronate) | Homo sapiens | FARNESYL DIPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 13 | PHE F 99LEU F 100ASP F 103ASP F 107ARG F 112THR F 167GLN F 171LYS F 200THR F 201TYR F 204GLN F 240ASP F 243LYS F 257 | BFQ F9001 |
2F9K_F_ZOLF9001 | 2f9k | ZOL DB00399(Zoledronicacid) | Homo sapiens | FARNESYL DIPHOSPHATESYNTHASE | PF00348(polyprenyl_synt) | 10 | LEU F 100ASP F 103ASP F 107ARG F 112GLN F 171LYS F 200THR F 201GLN F 240ASP F 243LYS F 257 | ZOL F9001 |