DRUG BINDING INTERFACES MAPPED TO 'FAB'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1DBB_H_STRH229 1dbb STR

DB00396
(Progesterone) 		Mus musculus IGG1-KAPPA DB3 FAB
(HEAVY CHAIN);
IGG1-KAPPA DB3 FAB
(LIGHT CHAIN) 		PF07654
(C1-set)
PF07686
(V-set) 		8 HIS L  27
GLY H  33
ASN H  35
TRP H  50
VAL L  94
GLY H  95
TYR H  97
TRP H 100
 STR H 229
1I9J_H_TESH1010 1i9j TES

DB00624
(Testosterone) 		Mus musculus RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN;
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		11 SER H  35
TRP H  47
SER H  50
VAL H  52
TYR H  58
GLU H  98
VAL L  99
PRO L 101
TYR H 102
GLY H 104
LEU H 105
 TES H1010
1IBG_H_OBNH1 1ibg OBN

DB01092
(Ouabain) 		Mus musculus IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN);
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN) 		PF07654
(C1-set)
PF07686
(V-set) 		13 THR L  27
SER L  28
HIS L  32
HIS H  35
LEU H  50
TRP H  52
SER L  91
ARG L  92
TYR L  94
PHE H  95
LEU L  96
TYR H 100
VAL H 100
 OBN H   1
1IGJ_B_DGXB228 1igj DGX

DB00390
(Digoxin) 		Mus musculus IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN);
IGG2A-KAPPA 26-10
FAB (LIGHT CHAIN) 		PF07654
(C1-set)
PF07686
(V-set) 		10 TYR B  33
ASN B  35
TYR A  36
TYR B  47
TYR B  50
THR A  91
SER B  95
PRO A  96
MET B 100
TRP B 100
 DGX B 228
1IGJ_D_DGXD228 1igj DGX

DB00390
(Digoxin) 		Mus musculus IGG2A-KAPPA 26-10
FAB (HEAVY CHAIN);
IGG2A-KAPPA 26-10
FAB (LIGHT CHAIN) 		no annotation 9 TYR D  33
ASN D  35
TYR D  47
TYR D  50
THR C  91
SER D  95
PRO C  96
TRP D 100
MET D 100
 DGX D 228
1Q0Y_H_MOIH401 1q0y MOI

DB00295
(Morphine) 		Mus musculus FAB 9B1, HEAVY
CHAIN;
FAB 9B1, LIGHT CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		7 TRP H  33
GLU H  35
GLU H  50
ILE H  58
TRP L  91
TRP H  95
LEU H  97
 MOI H 401
1Q72_H_COCH401 1q72 COC

DB00907
(Cocaine) 		Mus musculus FAB M82G2, HEAVY
CHAIN;
FAB M82G2, LIGHT
CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		10 HIS L  27
TYR L  32
TRP H  33
ASN H  52
HIS L  91
TYR L  94
VAL H  95
PHE L  96
GLN H  97
GLY H  99
 COC H 401
2AJV_L_COCL501 2ajv COC

DB00907
(Cocaine) 		Mus musculus ANTIBODY 7A1 FAB' PF07654
(C1-set)
PF07686
(V-set) 		7 TYR L  27
TYR L  32
ALA H  34
TYR H  50
ARG H  52
PHE L  96
TYR H  97
 COC L 501
2AJY_H_BEZH306 2ajy BEZ

DB03793
(Benzoic
Acid) 		Mus musculus ANTIBODY 7A1 FAB' PF07654
(C1-set)
PF07686
(V-set) 		4 ASN H  32
ALA H  34
ARG H  52
TYR H  97
 BEZ H 306
2AK1_H_BEZH401 2ak1 BEZ

DB03793
(Benzoic
Acid) 		Mus musculus ANTIBODY 7A1 FAB' PF07654
(V-set)
PF07686
(C1-set) 		4 ASN H  32
ALA H  34
ARG H  52
TYR H  97
 BEZ H 401
2O5Y_H_STRH249 2o5y STR

DB00396
(Progesterone) 		Homo sapiens;
Mus musculus 		CHIMERIC ANTIBODY
FAB 1E9-DB3 		PF07654
(C1-set)
PF07686
(V-set) 		7 ASN H  35
TRP H  50
SER L  91
GLY H  95
THR H  97
MET H 100
TRP H 100
 STR H 249
2YK1_H_NCTH300 2yk1 NCT

DB00184
(Nicotine) 		Homo sapiens FAB FRAGMENT, HEAVY
CHAIN;
FAB FRAGMENT, LIGHT
CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		10 ILE H  29
GLY H  31
TYR L  34
TYR L  36
SER H  50
ALA L  89
VAL H  93
TRP H  95
TRP L  96
GLU H 101
 NCT H 300
3LS4_H_TCIH220 3ls4 TCI

DB00470
(Dronabinol) 		Mus musculus HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT;
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT 		PF07654
(C1-set)
PF07686
(V-set) 		15 VAL H  33
VAL H  35
LEU H  37
TYR L  37
TRP H  47
SER H  50
TYR H  58
GLN L  90
ILE L  95
LEU L  97
GLY H  98
PHE L  99
VAL H 102
GLY H 104
TRP H 107
 TCI H 220
3WFH_B_P2EB301 3wfh P2E

DB00917
(Dinoprostone) 		Mus musculus MAB FAB H FRAGMENT;
MAB FAB L FRAGMENT 		PF07654
(C1-set)
PF07686
(V-set) 		12 HIS B  31
PHE A  33
HIS A  35
TYR B  37
VAL A  37
GLU B  39
TRP A  50
LEU B  94
HIS A  99
TYR A 101
PRO A 105
TRP A 107
 P2E B 301
3WHX_B_XPGB301 3whx XPG

DB00770
(Alprostadil) 		Mus musculus MAB FAB H FRAGMENT;
MAB FAB L FRAGMENT 		PF07654
(C1-set)
PF07686
(V-set) 		12 HIS B  31
PHE A  33
HIS A  35
TYR B  37
VAL A  37
GLU B  39
TRP A  50
LEU B  94
HIS A  99
TYR A 101
PRO A 105
TRP A 107
 XPG B 301
4M93_B_ACTB303 4m93 ACT

DB03166
(Acetic
acid) 		Mus musculus S25-26 FAB (IGG1K)
HEAVY CHAIN;
S25-26 FAB (IGG1K)
LIGHT CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		5 GLY B 127
SER B 128
ALA B 129
PHE C 209
GLU C 213
 ACT B 303
4M93_B_ACTB304 4m93 ACT

DB03166
(Acetic
acid) 		Mus musculus S25-26 FAB (IGG1K)
HEAVY CHAIN;
S25-26 FAB (IGG1K)
LIGHT CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		4 PRO C 119
GLY B 127
SER B 128
ARG B 213
 ACT B 304
4M93_B_ACTB305 4m93 ACT

DB03166
(Acetic
acid) 		Mus musculus S25-26 FAB (IGG1K)
HEAVY CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		4 SER B  19
THR B  21
PHE B  79
LYS B  81
 ACT B 305
4UIL_H_QI9H1223 4uil QI9

DB00468
(Quinine) 		Mus musculus FAB 314.1 PF07654
(C1-set)
PF07686
(V-set) 		12 TRP H  33
HIS H  35
ALA H  50
SER H  59
GLN L  89
GLN L  90
GLY L  91
LEU L  94
PRO L  96
GLU H  99
GLY H 105
PHE H 109
 QI9 H1223
4UIN_H_QI9H1226 4uin QI9

DB00468
(Quinine) 		Mus musculus FAB 314.3 PF07654
(C1-set)
PF07686
(V-set) 		12 TRP H  33
HIS H  35
TRP H  47
THR H  50
SER H  59
GLY L  91
LEU L  94
PRO L  96
GLU H  99
GLY H 105
ARG H 107
PHE H 109
 QI9 H1226
5ALC_L_TIQL1210 5alc TIQ

DB08816
(Ticagrelor) 		Homo sapiens ANTI-TICAGRELOR FAB
72, HEAVY CHAIN;
ANTI-TICAGRELOR FAB
72, LIGHT CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		17 SER L  34
HIS H  35
TYR L  36
TRP H  47
ILE H  52
THR H  56
SER H  58
GLY L  89
TRP L  91
ILE L  93
SER L  95
GLY L  96
PHE L  98
TYR H  99
ASP H 100
LEU H 100
PRO H 100
 TIQ L1210
5ICX_E_SC2E1 5icx SC2

DB06151
(Acetylcysteine) 		Homo sapiens;
Mus musculus;
synthetic
construct 		CETUXIMAB FAB LIGHT
CHAIN;
MEDITOPE 		PF07654
(C1-set)
PF07686
(V-set)
no annotation 		3 GLN E   2
VAL A   9
CYS E  12
 SC2 E   1
5ICX_F_SC2F1 5icx SC2

DB06151
(Acetylcysteine) 		Homo sapiens;
Mus musculus;
synthetic
construct 		CETUXIMAB FAB LIGHT
CHAIN;
MEDITOPE 		no annotation 3 GLN F   2
VAL C   9
CYS F  12
 SC2 F   1
5MTH_A_ACTA301 5mth ACT

DB03166
(Acetic
acid) 		Mus musculus ANTIBODY FAB HEAVY
CHAIN 		None
PF07654
(C1-set)
PF07686
(V-set) 		4 PRO H 125
THR A 211
THR H 211
VAL A 213
 ACT A 301
5MTH_A_ACTA302 5mth ACT

DB03166
(Acetic
acid) 		Mus musculus ANTIBODY FAB HEAVY
CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		5 SER A 119
ALA A 121
PHE A 153
LEU A 177
ASP A 180
 ACT A 302
5MTH_B_ACTB302 5mth ACT

DB03166
(Acetic
acid) 		Mus musculus ANTIBODY FAB HEAVY
CHAIN;
ANTIBODY FAB LIGHT
CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		5 GLU A  50
TYR A  59
TYR B  99
TYR A 101
ARG B 101
 ACT B 302
5MTH_H_ACTH304 5mth ACT

DB03166
(Acetic
acid) 		Mus musculus ANTIBODY FAB HEAVY
CHAIN;
ANTIBODY FAB LIGHT
CHAIN 		None 5 GLU H  50
TYR H  59
TYR L  99
TYR H 101
ARG L 101
 ACT H 304
6CJK_B_ACTB301 6cjk ACT

DB03166
(Acetic
acid) 		Oryctolagus
cuniculus 		IMMUNOGLOBULIN FAB
HEAVY CHAIN 		None
PF07654
(C1-set)
PF07686
(V-set) 		3 LYS D  43
ARG B  61
ALA D  85
 ACT B 301
6CJK_B_ACTB302 6cjk ACT

DB03166
(Acetic
acid) 		Oryctolagus
cuniculus 		IMMUNOGLOBULIN FAB
HEAVY CHAIN 		PF07654
(C1-set)
PF07686
(V-set) 		3 TYR B  59
GLY B  65
THR B  68
 ACT B 302
6CJK_C_ACTC301 6cjk ACT

DB03166
(Acetic
acid) 		Oryctolagus
cuniculus 		IMMUNOGLOBULIN FAB
LIGHT CHAIN 		None 4 VAL C  15
GLY C 108
ASP C 109
ASP C 169
 ACT C 301