DRUG BINDING INTERFACES MAPPED TO 'DNA TOPOISOMERASE 4 SUBUNIT A'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
3FOF_F_MFXF0
3fof
MFX
DB00218(Moxifloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A
no annotation
3
GLY B 77SER B 79SER B 80
MFX F 0
3FOF_H_MFXH0
3fof
MFX
DB00218(Moxifloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
4
GLY A 77SER A 79SER A 80ARG C 456
MFX H 0
3K9F_F_LFXF0
3k9f
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
5
SER A 79ARG B 117ARG C 456GLY C 457GLU C 475
LFX F 0
3K9F_H_LFXH0
3k9f
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)no annotation
6
SER B 79ARG A 117ARG D 456GLY D 457GLU D 474GLU D 475
LFX H 0
3RAE_F_LFXF101
3rae
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
4
SER A 79ARG C 456GLY C 457GLU C 474
LFX F 101
3RAE_H_LFXH101
3rae
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B
no annotation
5
SER B 79ARG D 456GLY D 457GLU D 474GLU D 475
LFX H 101
4JUO_F_LFXF101
4juo
LFX
DB01137(Levofloxacin)DB01165(Ofloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B;E-SITE DNA
PF00204(DNA_gyraseB)PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)PF02518(HATPase_c)no annotation
4
SER A 79ARG C 456GLY C 457GLU C 474
LFX F 101
4KOE_F_TR6F101
4koe
TR6
DB00685(Trovafloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B;E-SITE DNA2
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
6
SER A 79ARG B 117GLY C 434ASP C 435ARG C 456GLY C 457
TR6 F 101
4KOE_H_TR6H101
4koe
TR6
DB00685(Trovafloxacin)
;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT A;DNA TOPOISOMERASE 4SUBUNIT B;E-SITE DNA4
PF00521(DNA_topoisoIV)no annotation
7
SER B 79ARG A 117GLY D 434ASP D 435ARG D 456GLY D 457GLU D 475
TR6 H 101
4Z53_F_TR6F101
4z53
TR6
DB00685(Trovafloxacin)
Escherichia coli;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT B,DNATOPOISOMERASE 4SUBUNIT A;E-SITE DNA
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
6
GLY A 434ASP A 435ARG A 456GLY A 457SER A1079ARG B1117
TR6 F 101
4Z53_H_TR6H101
4z53
TR6
DB00685(Trovafloxacin)
Escherichia coli;Streptococcuspneumoniae
DNA TOPOISOMERASE 4SUBUNIT B,DNATOPOISOMERASE 4SUBUNIT A;E-SITE DNA
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim)no annotation
7
GLY B 434ASP B 435ARG B 456GLY B 457GLU B 475SER B1079ARG A1117
TR6 H 101
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