DRUG BINDING INTERFACES MAPPED TO 'DNA TOPOISOMERASE 2-BETA'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
3QX3_A_EVPA1
3qx3
EVP
DB00773(Etoposide)
Homo sapiens
DNA TOPOISOMERASE2-BETA
PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C)
5
GLY A 478ASP A 479ARG A 503GLN A 778MET A 782
EVP A 1
3QX3_D_EVPD1
3qx3
EVP
DB00773(Etoposide)
;Homo sapiens
DNA TOPOISOMERASE2-BETA
no annotation
5
GLY B 478ASP B 479ARG B 503GLN B 778MET B 782
EVP D 1
4G0U_B_ASWB1301
4g0u
ASW
DB00276(Amsacrine)
Homo sapiens
DNA TOPOISOMERASE2-BETA
no annotation
7
ILE B 454PRO B 455ARG B 503GLY B 504ALA B 521GLU B 522GLN B 778
ASW B1301
4G0U_F_ASWF101
4g0u
ASW
DB00276(Amsacrine)
;Homo sapiens
DNA TOPOISOMERASE2-BETA
PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C)no annotation
6
PRO A 455ARG A 503GLY A 504ALA A 521GLU A 522GLN A 778
ASW F 101
4G0V_A_MIXA1301
4g0v
MIX
DB01204(Mitoxantrone)
Homo sapiens
DNA TOPOISOMERASE2-BETA
PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C)
7
ARG A 503GLY A 504ILE A 506ASN A 520GLU A 522GLN A 778MET A 782
MIX A1301
4G0V_D_MIXD101
4g0v
MIX
DB01204(Mitoxantrone)
;Homo sapiens
DNA TOPOISOMERASE2-BETA
no annotation
6
ARG B 503GLY B 504ASN B 520GLU B 522GLN B 778MET B 782
MIX D 101
[["3QX3_A_EVPA1","3qx3","EVP","DB00773(Etoposide)","Homo sapiens","DNA TOPOISOMERASE 2-BETA","PF00521(DNA_topoisoIV);PF01751(Toprim);PF16898(TOPRIM_C)",5,"GLY A 478;ASP A 479;ARG A 503;GLN A 778;MET A 782","EVP A 1\r"],["3QX3_D_EVPD1","3qx3","EVP","DB00773(Etoposide)",";Homo sapiens","DNA TOPOISOMERASE 2-BETA","no annotation",5,"GLY B 478;ASP B 479;ARG B 503;GLN B 778;MET B 782","EVP D 1\r"],["4G0U_B_ASWB1301","4g0u","ASW","DB00276(Amsacrine)","Homo sapiens","DNA TOPOISOMERASE 2-BETA","no annotation",7,"ILE B 454;PRO B 455;ARG B 503;GLY B 504;ALA B 521;GLU B 522;GLN B 778","ASW B1301\r"],["4G0U_F_ASWF101","4g0u","ASW","DB00276(Amsacrine)",";Homo sapiens","DNA TOPOISOMERASE 2-BETA","PF00521(DNA_topoisoIV);PF01751(Toprim);PF16898(TOPRIM_C);no annotation",6,"PRO A 455;ARG A 503;GLY A 504;ALA A 521;GLU A 522;GLN A 778","ASW F 101\r"],["4G0V_A_MIXA1301","4g0v","MIX","DB01204(Mitoxantrone)","Homo sapiens","DNA TOPOISOMERASE 2-BETA","PF00521(DNA_topoisoIV);PF01751(Toprim);PF16898(TOPRIM_C)",7,"ARG A 503;GLY A 504;ILE A 506;ASN A 520;GLU A 522;GLN A 778;MET A 782","MIX A1301\r"],["4G0V_D_MIXD101","4g0v","MIX","DB01204(Mitoxantrone)",";Homo sapiens","DNA TOPOISOMERASE 2-BETA","no annotation",6,"ARG B 503;GLY B 504;ASN B 520;GLU B 522;GLN B 778;MET B 782","MIX D 101\r"]]