DRUG BINDING INTERFACES MAPPED TO 'DNA TOPOISOMERASE 2-ALPHA'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 5GWK_D_EVPD102 | 5gwk | EVP DB00773(Etoposide) | Homo sapiens;syntheticconstruct | DNA TOPOISOMERASE2-ALPHA | no annotation | 4 | GLY B 462ASP B 463ARG B 487MET B 766 | EVP D 102 |
| 5GWK_F_EVPF102 | 5gwk | EVP DB00773(Etoposide) | Homo sapiens;syntheticconstruct | DNA TOPOISOMERASE2-ALPHA | PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C)no annotation | 5 | GLY A 462ASP A 463ARG A 487MET A 762MET A 766 | EVP F 102 |