DRUG BINDING INTERFACES MAPPED TO 'DIPEPTIDYL PEPTIDASE 4'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2RGU_A_356A901 | 2rgu | 356 DB08882(Linagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | PF00326(Peptidase_S9)PF00930(DPPIV_N) | 12 | GLU A 205GLU A 206PHE A 357TYR A 547TRP A 629SER A 630TYR A 631VAL A 656TYR A 662TYR A 666VAL A 711HIS A 740 | 356 A 901 |
| 2RGU_B_356B902 | 2rgu | 356 DB08882(Linagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 11 | GLU B 205GLU B 206TYR B 547TRP B 629SER B 630TYR B 631VAL B 656TYR B 662TYR B 666VAL B 711HIS B 740 | 356 B 902 |
| 3BJM_A_BJMA1 | 3bjm | BJM DB06335(Saxagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | PF00326(Peptidase_S9)PF00930(DPPIV_N) | 12 | ARG A 125GLU A 205GLU A 206TYR A 547SER A 630TYR A 631VAL A 656TYR A 662TYR A 666ASN A 710VAL A 711HIS A 740 | BJM A 1 |
| 3BJM_B_BJMB2 | 3bjm | BJM DB06335(Saxagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 13 | ARG B 125GLU B 205GLU B 206PHE B 357TYR B 547SER B 630TYR B 631VAL B 656TYR B 662TYR B 666ASN B 710VAL B 711HIS B 740 | BJM B 2 |
| 3G0B_A_T22A800 | 3g0b | T22 DB06203(Alogliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | PF00326(Peptidase_S9)PF00930(DPPIV_N) | 12 | ARG A 125GLU A 205GLU A 206TYR A 547SER A 630TYR A 631VAL A 656TYR A 662TYR A 666ASN A 710VAL A 711HIS A 740 | T22 A 800 |
| 3G0B_B_T22B800 | 3g0b | T22 DB06203(Alogliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 12 | ARG B 125GLU B 205GLU B 206TYR B 547SER B 630TYR B 631VAL B 656TYR B 662TYR B 666ASN B 710VAL B 711HIS B 740 | T22 B 800 |
| 3G0B_C_T22C800 | 3g0b | T22 DB06203(Alogliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 12 | ARG C 125GLU C 205GLU C 206TYR C 547SER C 630TYR C 631VAL C 656TYR C 662TYR C 666ASN C 710VAL C 711HIS C 740 | T22 C 800 |
| 3G0B_D_T22D800 | 3g0b | T22 DB06203(Alogliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 12 | ARG D 125GLU D 205GLU D 206TYR D 547SER D 630TYR D 631VAL D 656TYR D 662TYR D 666ASN D 710VAL D 711HIS D 740 | T22 D 800 |
| 3W2T_A_LF7A801 | 3w2t | LF7 DB04876(Vildagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | PF00326(Peptidase_S9)PF00930(DPPIV_N) | 12 | ARG A 125GLU A 205GLU A 206TYR A 547SER A 630TYR A 631VAL A 656TYR A 662TYR A 666ASN A 710VAL A 711HIS A 740 | LF7 A 801 |
| 3W2T_B_LF7B801 | 3w2t | LF7 DB04876(Vildagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 12 | ARG B 125GLU B 205GLU B 206TYR B 547SER B 630TYR B 631VAL B 656TYR B 662TYR B 666ASN B 710VAL B 711HIS B 740 | LF7 B 801 |
| 4FFW_A_715A801 | 4ffw | 715 DB01261(Sitagliptin) | Rattus norvegicus | DIPEPTIDYL PEPTIDASE4 | PF00326(Peptidase_S9)PF00930(DPPIV_N) | 15 | ARG A 123GLU A 203GLU A 204GLY A 207PHE A 355ARG A 356TYR A 548SER A 631TYR A 632VAL A 657TYR A 663TYR A 667ASN A 711VAL A 712HIS A 741 | 715 A 801 |
| 4FFW_B_715B801 | 4ffw | 715 DB01261(Sitagliptin) | Rattus norvegicus | DIPEPTIDYL PEPTIDASE4 | no annotation | 15 | ARG B 123GLU B 203GLU B 204GLY B 207PHE B 355ARG B 356TYR B 548SER B 631TYR B 632VAL B 657TYR B 663TYR B 667ASN B 711VAL B 712HIS B 741 | 715 B 801 |
| 6B1E_A_LF7A801 | 6b1e | LF7 DB04876(Vildagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | PF00326(Peptidase_S9)PF00930(DPPIV_N) | 11 | ARG A 125GLU A 205GLU A 206TYR A 547SER A 630TYR A 631VAL A 656TYR A 662TYR A 666ASN A 710VAL A 711 | LF7 A 801 |
| 6B1E_B_LF7B801 | 6b1e | LF7 DB04876(Vildagliptin) | Homo sapiens | DIPEPTIDYL PEPTIDASE4 | no annotation | 12 | ARG B 125GLU B 205GLU B 206TYR B 547SER B 630TYR B 631VAL B 656TYR B 662TYR B 666ASN B 710VAL B 711HIS B 740 | LF7 B 801 |