DRUG BINDING INTERFACES MAPPED TO 'DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
6DWD_A_GLYA715 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None
PF01966
(HD)
6 GLY A 357
ASN A 358
ASP A 361
SER C 368
ARG C 371
ARG C 372
GLY A 715
6DWD_A_GLYA717 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
PF01966
(HD)
5 SER A 192
ARG A 194
ASP A 195
ARG A 290
LYS A 294
GLY A 717
6DWD_B_GLYB709 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 5 GLY B 357
ASN B 358
ASP B 361
ARG D 371
ARG D 372
GLY B 709
6DWD_C_GLYC713 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 3 GLN C 447
TYR C 450
ASN C 452
GLY C 713
6DWD_D_GLYD713 6dwd GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 3 ARG D 305
HIS D 517
ARG D 531
GLY D 713
6DWJ_B_GLYB710 6dwj GLY

DB00145
(Glycine)
Homo sapiens DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1
None 5 GLY D 357
ASN D 358
ASP D 361
ARG B 371
ARG B 372
GLY B 710