DRUG BINDING INTERFACES MAPPED TO 'DEOXYCYTIDINE KINASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1P5Z_B_AR3B304 | 1p5z | AR3 DB00987(Cytarabine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 12 | ILE B 30GLU B 53VAL B 55TRP B 58LEU B 82MET B 85TYR B 86GLN B 97ARG B 128ASP B 133PHE B 137GLU B 197 | AR3 B 304 |
1P62_B_GEOB302 | 1p62 | GEO DB00441(Gemcitabine) | Mus musculus | DEOXYCYTIDINE KINASE | PF01712(dNK) | 11 | ILE B 30GLU B 53VAL B 55TRP B 58MET B 85TYR B 86GLN B 97ARG B 128ASP B 133PHE B 137GLU B 197 | GEO B 302 |
2A7Q_A_CFBA328 | 2a7q | CFB DB00631(Clofarabine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 16 | ILE A 30GLU A 53VAL A 55TRP A 58MET A 85TYR A 86PHE A 96GLN A 97ARG A 104ARG A 128ASP A 133PHE A 137LEU A 141ARG A 194GLU A 197TYR A 204 | CFB A 328 |
2NO0_A_GEOA302 | 2no0 | GEO DB00441(Gemcitabine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 14 | ILE A 30GLU A 53VAL A 55TRP A 58LEU A 82MET A 85TYR A 86PHE A 96GLN A 97ARG A 128ASP A 133PHE A 137ARG A 194GLU A 197 | GEO A 302 |
2NO0_B_GEOB302 | 2no0 | GEO DB00441(Gemcitabine) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 14 | ILE B 30GLU B 53VAL B 55TRP B 58LEU B 82MET B 85TYR B 86PHE B 96GLN B 97ARG B 128ASP B 133PHE B 137ARG B 194GLU B 197 | GEO B 302 |
2NO6_A_ETVA302 | 2no6 | ETV DB00879(Emtricitabine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 12 | ILE A 30GLU A 53TRP A 58LEU A 82MET A 85TYR A 86GLN A 97ARG A 104ARG A 128ASP A 133PHE A 137TYR A 204 | ETV A 302 |
2NO6_B_ETVB302 | 2no6 | ETV DB00879(Emtricitabine) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 11 | ILE B 30GLU B 53TRP B 58LEU B 82MET B 85TYR B 86GLN B 97ARG B 104ARG B 128ASP B 133PHE B 137 | ETV B 302 |
2NOA_A_3TCA302 | 2noa | 3TC DB00709(Lamivudine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 14 | ILE A 30GLU A 53TRP A 58LEU A 82MET A 85TYR A 86PHE A 96GLN A 97ALA A 100ARG A 104ARG A 128ASP A 133PHE A 137ARG A 194 | 3TC A 302 |
2NOA_B_3TCB302 | 2noa | 3TC DB00709(Lamivudine) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 11 | ILE B 30GLU B 53TRP B 58LEU B 82TYR B 86GLN B 97ALA B 100ARG B 104ARG B 128ASP B 133PHE B 137 | 3TC B 302 |
2ZI9_A_CL9A401 | 2zi9 | CL9 DB00242(Cladribine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 15 | ILE A 30GLU A 53TRP A 58MET A 85TYR A 86PHE A 96GLN A 97ARG A 104ARG A 128ASP A 133PHE A 137LEU A 141ARG A 194GLU A 197TYR A 204 | CL9 A 401 |
2ZI9_B_CL9B401 | 2zi9 | CL9 DB00242(Cladribine) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 14 | ILE B 30GLU B 53TRP B 58MET B 85TYR B 86PHE B 96GLN B 97ARG B 104ARG B 128ASP B 133PHE B 137ARG B 192GLU B 197TYR B 204 | CL9 B 401 |
2ZIA_A_CL9A401 | 2zia | CL9 DB00242(Cladribine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 16 | ILE A 30GLU A 53VAL A 55TRP A 58LEU A 82MET A 85TYR A 86GLN A 97ARG A 104ARG A 128ASP A 133PHE A 137LEU A 141ARG A 194GLU A 197TYR A 204 | CL9 A 401 |
2ZIA_B_CL9B401 | 2zia | CL9 DB00242(Cladribine) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 16 | ILE B 30GLU B 53VAL B 55TRP B 58LEU B 82MET B 85TYR B 86GLN B 97ARG B 104ARG B 128ASP B 133PHE B 137LEU B 141ARG B 194GLU B 197TYR B 204 | CL9 B 401 |
3HP1_A_LLTA401 | 3hp1 | LLT DB01265(Telbivudine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 13 | GLU A 53VAL A 55TRP A 58LEU A 82MET A 85TYR A 86PHE A 96GLN A 97MET A 104ARG A 128ALA A 133PHE A 137GLU A 197 | LLT A 401 |
3MJR_A_AC2A301 | 3mjr | AC2 DB00787(Aciclovir) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 9 | ILE A 30GLU A 53GLN A 97ARG A 104ARG A 128ASP A 133PHE A 137TYR A 204LEU A 208 | AC2 A 301 |
3MJR_B_AC2B401 | 3mjr | AC2 DB00787(Aciclovir) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 9 | ILE B 30GLU B 53VAL B 55PHE B 96GLN B 97ARG B 104ARG B 128ASP B 133PHE B 137 | AC2 B 401 |
3MJR_D_AC2D601 | 3mjr | AC2 DB00787(Aciclovir) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 8 | GLU D 53TYR D 86PHE D 96GLN D 97ARG D 104ARG D 128ASP D 133PHE D 137 | AC2 D 601 |
3QEO_A_LLTA261 | 3qeo | LLT DB01265(Telbivudine) | Homo sapiens | DEOXYCYTIDINE KINASE | PF01712(dNK) | 10 | GLU A 53VAL A 55LEU A 82MET A 85TYR A 86GLN A 97ARG A 128PHE A 137LEU A 141GLU A 197 | LLT A 261 |
3QEO_B_LLTB261 | 3qeo | LLT DB01265(Telbivudine) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 7 | GLU B 53VAL B 55LEU B 82TYR B 86GLN B 97PHE B 137LEU B 141 | LLT B 261 |
5MQT_A_STIA302 | 5mqt | STI DB00619(Imatinib) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 12 | ILE A 30VAL A 55MET A 85TYR A 86PRO A 89GLU A 90GLN A 97ARG A 128PHE A 137SER A 144CYS A 146GLU A 197 | STI A 302 |
5MQT_C_STIC302 | 5mqt | STI DB00619(Imatinib) | Homo sapiens | DEOXYCYTIDINE KINASE | no annotation | 13 | ILE C 30GLU C 53VAL C 55LEU C 82MET C 85PRO C 89GLU C 90GLN C 97ARG C 128LEU C 141GLU C 196GLU C 197TYR C 204 | STI C 302 |