DRUG BINDING INTERFACES MAPPED TO 'CYTOCHROME P450 2C9'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 1OG5_A_SWFA502 | 1og5 | SWF DB00682(Warfarin) | Homo sapiens | CYTOCHROME P450 2C9 | PF00067(p450) | 13 | ARG A 97PHE A 100LEU A 102ALA A 103VAL A 113PHE A 114LEU A 208ASN A 217THR A 364LEU A 366PRO A 367LEU A 388PHE A 476 | SWF A 502 |
| 1OG5_B_SWFB502 | 1og5 | SWF DB00682(Warfarin) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 13 | ARG B 97ILE B 99PHE B 100LEU B 102ALA B 103VAL B 113PHE B 114ASN B 217THR B 364LEU B 366PRO B 367LEU B 388PHE B 476 | SWF B 502 |
| 1R9O_A_FLPA501 | 1r9o | FLP DB00712(Flurbiprofen) | Homo sapiens | CYTOCHROME P450 2C9 | PF00067(p450) | 13 | ARG A 108VAL A 113ASN A 204ILE A 205LEU A 208VAL A 237MET A 240VAL A 292ASP A 293GLY A 296ALA A 297THR A 301LEU A 366 | FLP A 501 |
| 5X23_A_LSNA502 | 5x23 | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 15 | ALA A 106ARG A 108VAL A 113PHE A 114LEU A 201ASN A 204LEU A 208VAL A 237MET A 240VAL A 292ASP A 293GLY A 296ALA A 297LEU A 362LEU A 366 | LSN A 502 |
| 5X23_A_LSNA503 | 5x23 | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 5 | PRO A 227GLY A 228THR A 229ASN A 231LYS A 232 | LSN A 503 |
| 5X23_A_LSNA504 | 5x23 | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 8 | PHE A 69ILE A 74PHE A 100ASN A 218PRO A 363THR A 364PRO A 367PHE A 476 | LSN A 504 |
| 5X24_A_LSNA502 | 5x24 | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 13 | ALA A 106ARG A 108PHE A 114ASN A 204LEU A 233VAL A 237MET A 240VAL A 292ASP A 293GLY A 296GLU A 300THR A 301LEU A 366 | LSN A 502 |
| 5X24_A_LSNA503 | 5x24 | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 6 | PHE A 226PRO A 227GLY A 228THR A 229ASN A 231LYS A 232 | LSN A 503 |
| 5XXI_A_LSNA501 | 5xxi | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 16 | ALA A 106ARG A 108VAL A 113PHE A 114LEU A 201ASN A 204LEU A 208GLN A 214VAL A 237MET A 240VAL A 292ASP A 293GLY A 296ALA A 297LEU A 362LEU A 366 | LSN A 501 |
| 5XXI_A_LSNA502 | 5xxi | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 6 | PRO A 227GLY A 228THR A 229ASN A 231LYS A 232LYS A 235 | LSN A 502 |
| 5XXI_A_LSNA503 | 5xxi | LSN DB00678(Losartan) | Homo sapiens | CYTOCHROME P450 2C9 | no annotation | 12 | ILE A 74PHE A 100LEU A 102PHE A 114GLN A 214ASN A 218LEU A 362PRO A 363THR A 364PRO A 367LEU A 388PHE A 476 | LSN A 503 |