DRUG BINDING INTERFACES MAPPED TO 'CYTOCHROME P450 2C8'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2NNH_A_9CRA501 | 2nnh | 9CR DB00523(Alitretinoin) | Homo sapiens | CYTOCHROME P450 2C8 | PF00067(p450) | 11 | ARG A 97GLY A 98SER A 100SER A 103ILE A 113SER A 114ALA A 297THR A 301VAL A 366PRO A 367ILE A 476 | 9CR A 501 |
| 2NNH_A_9CRA502 | 2nnh | 9CR DB00523(Alitretinoin) | Homo sapiens | CYTOCHROME P450 2C8 | PF00067(p450) | 12 | SER A 100ILE A 102SER A 103ILE A 106ASN A 204LEU A 208ASN A 209ASN A 217VAL A 237ARG A 241VAL A 296ILE A 476 | 9CR A 502 |
| 2NNH_B_9CRB501 | 2nnh | 9CR DB00523(Alitretinoin) | Homo sapiens | CYTOCHROME P450 2C8 | no annotation | 9 | ARG B 97GLY B 98SER B 100ILE B 113THR B 301VAL B 366PRO B 367ILE B 476VAL B 477 | 9CR B 501 |
| 2NNH_B_9CRB502 | 2nnh | 9CR DB00523(Alitretinoin) | Homo sapiens | CYTOCHROME P450 2C8 | no annotation | 10 | SER B 100ILE B 102ILE B 106ASN B 204LEU B 208ASN B 209ASN B 217ARG B 241VAL B 296ILE B 476 | 9CR B 502 |
| 2NNI_A_MTKA501 | 2nni | MTK DB00471(Montelukast) | Homo sapiens | CYTOCHROME P450 2C8 | PF00067(p450) | 20 | SER A 100ILE A 102SER A 103ILE A 106THR A 107ILE A 113SER A 114ARG A 200ASN A 204ILE A 213ASN A 217ASN A 236VAL A 237THR A 240ALA A 292VAL A 296ALA A 297THR A 301VAL A 366VAL A 477 | MTK A 501 |
| 2NNJ_A_225A501 | 2nnj | 225 DB01023(Felodipine) | Homo sapiens | CYTOCHROME P450 2C8 | PF00067(p450) | 10 | ILE A 113LEU A 208VAL A 296ALA A 297THR A 301VAL A 362VAL A 366PRO A 367ILE A 476VAL A 477 | 225 A 501 |
| 2VN0_A_TDZA501 | 2vn0 | TDZ DB00197(Troglitazone) | Homo sapiens | CYTOCHROME P450 2C8 | PF00067(p450) | 12 | ILE A 106THR A 107ASN A 204PHE A 205LEU A 208ASN A 209VAL A 237ARG A 241VAL A 296GLU A 300THR A 301ILE A 476 | TDZ A 501 |