DRUG BINDING INTERFACES MAPPED TO 'CYTOCHROME P450 2B4'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2BDM_A_TMIA501 | 2bdm | TMI DB04794(Bifonazole) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 7 | SER A 128MET A 132LEU A 295PHE A 296GLY A 299THR A 302ILE A 363 | TMI A 501 |
| 2BDM_A_TMIA502 | 2bdm | TMI DB04794(Bifonazole) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 12 | PHE A 184LEU A 198LEU A 201LEU A 238ILE A 241ILE A 245ASN A 287LEU A 290THR A 291LEU A 293SER A 294PHE A 297 | TMI A 502 |
| 2BDM_A_TMIA503 | 2bdm | TMI DB04794(Bifonazole) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 8 | GLN A 45MET A 46ARG A 48LEU A 51VAL A 68LEU A 70VAL A 104VAL A 477 | TMI A 503 |
| 3KW4_A_TICA600 | 3kw4 | TIC DB00208(Ticlopidine) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 11 | ILE A 114ILE A 209SER A 210PHE A 297ALA A 298GLU A 301THR A 302ILE A 363VAL A 367VAL A 477GLY A 478 | TIC A 600 |
| 3ME6_A_CGEA501 | 3me6 | CGE DB00758(Clopidogrel) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 10 | VAL A 104PHE A 108PHE A 206ILE A 209PHE A 297ALA A 298THR A 302ILE A 363VAL A 367VAL A 477 | CGE A 501 |
| 3ME6_B_CGEB501 | 3me6 | CGE DB00758(Clopidogrel) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | no annotation | 8 | PHE B 108PHE B 206ILE B 209PHE B 297ALA B 298THR B 302VAL B 367VAL B 477 | CGE B 501 |
| 3ME6_C_CGEC501 | 3me6 | CGE DB00758(Clopidogrel) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | no annotation | 9 | VAL C 104PHE C 108PHE C 206ILE C 209PHE C 297ALA C 298THR C 302VAL C 367VAL C 477 | CGE C 501 |
| 3ME6_D_CGED501 | 3me6 | CGE DB00758(Clopidogrel) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | no annotation | 9 | VAL D 104PHE D 108PHE D 206ILE D 209PHE D 297ALA D 298THR D 302VAL D 367VAL D 477 | CGE D 501 |
| 3TMZ_A_06XA503 | 3tmz | 06X DB00381(Amlodipine) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 11 | ILE A 101ILE A 114PHE A 115PHE A 206ILE A 209ALA A 298GLU A 301THR A 302VAL A 367PRO A 368VAL A 477 | 06X A 503 |
| 3TMZ_A_06XA504 | 3tmz | 06X DB00381(Amlodipine) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 9 | LEU A 51LEU A 70ILE A 101ILE A 209GLN A 215GLU A 218PHE A 365GLU A 387VAL A 477 | 06X A 504 |
| 4H1N_A_CGEA505 | 4h1n | CGE DB00758(Clopidogrel) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 11 | ILE A 101ILE A 114PHE A 202ILE A 209LEU A 238ALA A 297ALA A 298THR A 302ILE A 363VAL A 367VAL A 477 | CGE A 505 |
| 4JLT_A_8PRA505 | 4jlt | 8PR DB00715(Paroxetine) | Oryctolaguscuniculus | CYTOCHROME P450 2B4 | PF00067(p450) | 8 | ILE A 101ILE A 114GLU A 218ALA A 298GLU A 301VAL A 367PRO A 368VAL A 477 | 8PR A 505 |