DRUG BINDING INTERFACES MAPPED TO 'CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
3SI7_A_ACTA4 3si7 ACT

DB03166
(Acetic
acid)
Mus musculus CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR
PF00005
(ABC_tran)
PF14396
(CFTR_R)
4 LEU A 541
GLY A 542
GLY A 545
THR A 547
ACT A   4
3SI7_A_ACTA5 3si7 ACT

DB03166
(Acetic
acid)
Mus musculus CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR
PF00005
(ABC_tran)
PF14396
(CFTR_R)
3 LYS A 532
SER A 549
GLN A 552
ACT A   5
3SI7_B_ACTB4 3si7 ACT

DB03166
(Acetic
acid)
Mus musculus CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR
None 3 GLY B 542
GLY B 545
THR B 547
ACT B   4
3SI7_C_ACTC4 3si7 ACT

DB03166
(Acetic
acid)
Mus musculus CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR
None 4 GLY C 542
GLY C 545
THR C 547
LEU D 578
ACT C   4
3SI7_D_ACTD4 3si7 ACT

DB03166
(Acetic
acid)
Mus musculus CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR
None 5 LEU D 541
GLY D 542
GLY D 545
THR D 547
LEU C 578
ACT D   4
3SI7_D_ACTD5 3si7 ACT

DB03166
(Acetic
acid)
Mus musculus CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR
None 6 LYS C 532
LYS D 532
SER D 549
SER C 549
GLN C 552
GLN D 552
ACT D   5