DRUG BINDING INTERFACES MAPPED TO 'CHOLESTEROL 24-HYDROXYLASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 3MDR_A_GJZA506 | 3mdr | GJZ DB00752(Tranylcypromine) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 6 | LEU A 112PHE A 121ILE A 301ALA A 302THR A 306THR A 475 | GJZ A 506 |
| 3MDR_B_GJZB506 | 3mdr | GJZ DB00752(Tranylcypromine) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | no annotation | 6 | PHE B 121ILE B 301ALA B 302THR B 306ALA B 367THR B 475 | GJZ B 506 |
| 3MDT_A_VORA506 | 3mdt | VOR DB00582(Voriconazole) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 9 | LEU A 112PHE A 121VAL A 126SER A 127ILE A 301ALA A 302THR A 306ALA A 367THR A 475 | VOR A 506 |
| 3MDT_B_VORB506 | 3mdt | VOR DB00582(Voriconazole) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | no annotation | 11 | TYR B 109LEU B 112PHE B 121VAL B 126SER B 127ILE B 222ALA B 302THR B 306ALA B 367ALA B 474THR B 475 | VOR B 506 |
| 3MDV_A_CL6A506 | 3mdv | CL6 DB00257(Clotrimazole) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 9 | LEU A 112PHE A 121VAL A 126LEU A 219ILE A 301ALA A 302GLU A 305ALA A 474THR A 475 | CL6 A 506 |
| 3MDV_B_CL6B506 | 3mdv | CL6 DB00257(Clotrimazole) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | no annotation | 12 | LEU B 112PHE B 121VAL B 126LEU B 219THR B 298ILE B 301ALA B 302GLU B 305THR B 306ALA B 367ALA B 474THR B 475 | CL6 B 506 |
| 4ENH_A_FVXA602 | 4enh | FVX DB00176(Fluvoxamine) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 12 | PHE A 80PHE A 121LEU A 219ILE A 222ILE A 301ALA A 302THR A 306ALA A 367TRP A 368GLY A 369ALA A 474THR A 475 | FVX A 602 |
| 4FIA_A_0U9A601 | 4fia | 0U9 DB01128(Bicalutamide) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 14 | PHE A 80TYR A 109LEU A 112PHE A 121VAL A 126ILE A 222ARG A 226ILE A 301ALA A 302THR A 306TRP A 368GLU A 472ALA A 474THR A 475 | 0U9 A 601 |
| 4FIA_A_198A602 | 4fia | 198 DB01128(Bicalutamide) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 14 | PHE A 80TYR A 109LEU A 112PHE A 121VAL A 126ILE A 222ARG A 226ILE A 301ALA A 302THR A 306TRP A 368GLU A 472ALA A 474THR A 475 | 198 A 602 |
| 4J14_A_X2NA602 | 4j14 | X2N DB01263(Posaconazole) | Homo sapiens | CHOLESTEROL24-HYDROXYLASE | PF00067(p450) | 10 | ALA A 111LEU A 112PHE A 121VAL A 126ARG A 226ILE A 301ALA A 302THR A 306ALA A 367THR A 475 | X2N A 602 |