DRUG BINDING INTERFACES MAPPED TO 'CEST'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
4CSV_A_STIA1265 | 4csv | STI DB00619(Imatinib) | syntheticconstruct | SRC-ABL TYROSINEKINASE ANCESTOR | PF07714(Pkinase_Tyr) | 16 | VAL A 22ALA A 35LYS A 37GLU A 52ILE A 55MET A 56VAL A 65ILE A 79THR A 81TYR A 83MET A 84PHE A 125LEU A 136ALA A 146ASP A 147PHE A 148 | STI A1265 |
4LTW_A_486A302 | 4ltw | 486 DB00834(Mifepristone) | - | ANCESTRAL STEROIDRECEPTOR 2 | PF00104(Hormone_recep) | 13 | LEU A 42VAL A 43VAL A 46LYS A 50LEU A 60GLN A 63MET A 64ILE A 67GLN A 68MET A 224GLU A 227ILE A 228ALA A 231 | 486 A 302 |
4LTW_A_486A303 | 4ltw | 486 DB00834(Mifepristone) | - | ANCESTRAL STEROIDRECEPTOR 2 | PF00104(Hormone_recep) | 9 | THR A 27LEU A 31ALA A 109LEU A 113GLN A 205PHE A 206TYR A 209THR A 210LEU A 217 | 486 A 303 |
4LTW_A_STRA301 | 4ltw | STR DB00396(Progesterone) | - | ANCESTRAL STEROIDRECEPTOR 2 | PF00104(Hormone_recep) | 20 | LEU A 31LEU A 34ASN A 35LEU A 37ALA A 38GLN A 41TRP A 71MET A 72MET A 75ALA A 76MET A 79ARG A 82MET A 110MET A 117LEU A 203PHE A 206CYS A 207THR A 210VAL A 219PHE A 221 | STR A 301 |