DRUG BINDING INTERFACES MAPPED TO 'CARBONIC ANHYDRASE I'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
---|---|---|---|---|---|---|---|---|
1AVN_A_HSMA264 | 1avn | HSM DB05381(Histamine) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 4 | ASN A 62HIS A 64ASN A 67GLN A 92 | HSM A 264 |
1AZM_A_AZMA262 | 1azm | AZM DB00819(Acetazolamide) | Homo sapiens | CARBONIC ANHYDRASE I | PF00194(Carb_anhydrase) | 8 | PHE A 91HIS A 94HIS A 96HIS A 119LEU A 198THR A 199HIS A 200TRP A 209 | AZM A 262 |
1BZM_A_MZMA262 | 1bzm | MZM DB00703(Methazolamide) | Homo sapiens | CARBONIC ANHYDRASE I | PF00194(Carb_anhydrase) | 8 | PHE A 91HIS A 94HIS A 96HIS A 119LEU A 198THR A 199HIS A 200TRP A 209 | MZM A 262 |
1CIL_A_ETSA263 | 1cil | ETS DB00869(Dorzolamide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 13 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131LEU A 141VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | ETS A 263 |
1OQ5_A_CELA701 | 1oq5 | CEL DB00482(Celecoxib) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 16 | ASN A 67GLU A 69GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 135VAL A 143LEU A 198THR A 199THR A 200PRO A 202LEU A 204TRP A 209 | CEL A 701 |
1YDA_A_AZMA264 | 1yda | AZM DB00819(Acetazolamide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 10 | GLN A 92HIS A 94HIS A 119VAL A 121PHE A 131VAL A 143GLU A 198THR A 199THR A 200TRP A 209 | AZM A 264 |
1YDB_A_AZMA264 | 1ydb | AZM DB00819(Acetazolamide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 11 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 143PHE A 198THR A 199THR A 200TRP A 209 | AZM A 264 |
1YDD_A_AZMA264 | 1ydd | AZM DB00819(Acetazolamide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 10 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 143ARG A 198THR A 199THR A 200 | AZM A 264 |
1Z9Y_A_FUNA500 | 1z9y | FUN DB00695(Furosemide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 13 | HIS A 64GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 135VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | FUN A 500 |
1ZGF_A_TRUA300 | 1zgf | TRU DB01021(Trichlormethiazide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 12 | HIS A 64ASN A 67GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | TRU A 300 |
1ZSB_A_AZMA264 | 1zsb | AZM DB00819(Acetazolamide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 12 | GLN A 92HIS A 94HIS A 96GLU A 106HIS A 119VAL A 121PHE A 131VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | AZM A 264 |
2AW1_A_COXA264 | 2aw1 | COX DB00580(Valdecoxib) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 14 | ILE A 91GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 131VAL A 135LEU A 141VAL A 143LEU A 198THR A 199THR A 200TRP A 209 | COX A 264 |
2H4N_A_AZMA264 | 2h4n | AZM DB00819(Acetazolamide) | Homo sapiens | CARBONIC ANHYDRASEII | PF00194(Carb_anhydrase) | 9 | GLN A 92ASN A 94HIS A 96HIS A 119VAL A 121PHE A 131THR A 199THR A 200TRP A 209 | AZM A 264 |
3ZNC_A_BZ1A500 | 3znc | BZ1 DB01194(Brinzolamide) | Mus musculus | CARBONIC ANHYDRASEIV | PF00194(Carb_anhydrase) | 10 | GLN A 92HIS A 94HIS A 96HIS A 119VAL A 121PHE A 141LEU A 198THR A 199THR A 200TRP A 209 | BZ1 A 500 |