DRUG BINDING INTERFACES MAPPED TO 'C3'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 1S2A_A_IMNA2001 | 1s2a | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 14 | TYR A 24LEU A 54TRP A 86HIS A 117SER A 118MET A 120GLU A 192TYR A 216SER A 217SER A 221GLN A 222TRP A 227TYR A 305PHE A 306 | IMN A2001 |
| 1XF0_A_ASDA600 | 1xf0 | ASD DB01536(4-Androstenedione) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 9 | LEU A 54TRP A 86MET A 120SER A 129ASN A 167TYR A 216TRP A 227PHE A 306PRO A 318 | ASD A 600 |
| 2C8A_A_NCAA1252 | 2c8a | NCA DB02701(Nicotinamide) | Clostridiumbotulinum | MONO-ADP-RIBOSYLTRANSFERASE C3 | PF03496(ADPrib_exo_Tox) | 7 | ARG A 128SER A 174SER A 176PHE A 183ARG A 186GLN A 212GLU A 214 | NCA A1252 |
| 2C8A_B_NCAB1246 | 2c8a | NCA DB02701(Nicotinamide) | Clostridiumbotulinum | MONO-ADP-RIBOSYLTRANSFERASE C3 | None | 7 | ARG B 128GLY B 129SER B 174SER B 176PHE B 183ARG B 186GLU B 214 | NCA B1246 |
| 2C8A_C_NCAC1252 | 2c8a | NCA DB02701(Nicotinamide) | Clostridiumbotulinum | MONO-ADP-RIBOSYLTRANSFERASE C3 | None | 6 | ARG C 128SER C 174SER C 176PHE C 183ARG C 186GLU C 214 | NCA C1252 |
| 2C8A_D_NCAD1247 | 2c8a | NCA DB02701(Nicotinamide) | Clostridiumbotulinum | MONO-ADP-RIBOSYLTRANSFERASE C3 | None | 7 | ARG D 128GLY D 129SER D 174SER D 176PHE D 183ARG D 186GLU D 214 | NCA D1247 |
| 2F38_A_15MA325 | 2f38 | 15M DB00905(Bimatoprost) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 13 | TYR A 24TRP A 86SER A 87SER A 118MET A 120LEU A 122SER A 129ASN A 167TRP A 227PHE A 306PHE A 311PRO A 318TYR A 319 | 15M A 325 |
| 3R43_A_ID8A332 | 3r43 | ID8 DB00784(Mefenamicacid) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 12 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117SER A 118MET A 120ASN A 167TYR A 216TRP A 227PHE A 306PHE A 311 | ID8 A 332 |
| 3R58_A_NPSA332 | 3r58 | NPS DB00788(Naproxen) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 10 | LEU A 54TYR A 55HIS A 117MET A 120ASN A 167TYR A 216PHE A 306PHE A 311PRO A 318TYR A 319 | NPS A 332 |
| 3R6I_A_JMSA332 | 3r6i | JMS DB00939(Meclofenamicacid) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 12 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117SER A 118MET A 120ASN A 167TYR A 216TRP A 227PHE A 306PHE A 311 | JMS A 332 |
| 3R7M_A_SUZA332 | 3r7m | SUZ DB00605(Sulindac) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 10 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117SER A 118ASN A 167TRP A 227PHE A 306PHE A 311 | SUZ A 332 |
| 3R8G_A_IZPA409 | 3r8g | IZP DB01050(Ibuprofen) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 9 | LEU A 54TYR A 55HIS A 117MET A 120ASN A 167TYR A 216PHE A 306PHE A 311PRO A 318 | IZP A 409 |
| 3R94_A_FLRA332 | 3r94 | FLR DB00712(Flurbiprofen) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 12 | LEU A 54TYR A 55HIS A 117SER A 118MET A 120ASN A 167TYR A 216TRP A 227PHE A 306PHE A 311PRO A 318TYR A 319 | FLR A 332 |
| 3UG8_A_IMNA2001 | 3ug8 | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 15 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117MET A 120ASN A 167GLU A 192TYR A 216SER A 217SER A 221TYR A 305PHE A 306PRO A 318TYR A 319 | IMN A2001 |
| 3UGR_A_IMNA2001 | 3ugr | IMN DB00328(Indomethacin) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 19 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117SER A 118MET A 120ASN A 167GLU A 192TYR A 216SER A 217SER A 221GLN A 222TRP A 227TYR A 305PHE A 306PHE A 311PRO A 318TYR A 319 | IMN A2001 |
| 4YVV_A_GBMA402 | 4yvv | GBM DB01016(Glyburide) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 9 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117ASN A 167TYR A 216TRP A 227PHE A 306 | GBM A 402 |
| 4YVV_B_GBMB402 | 4yvv | GBM DB01016(Glyburide) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | no annotation | 9 | TYR B 24LEU B 54TYR B 55TRP B 86HIS B 117SER B 118ASN B 167TRP B 227PHE B 306 | GBM B 402 |
| 4YVX_A_GMRA401 | 4yvx | GMR DB00222(Glimepiride) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 13 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117SER A 118LEU A 122SER A 129ASN A 167TRP A 227PHE A 306SER A 308PHE A 311 | GMR A 401 |
| 4YVX_B_GMRB401 | 4yvx | GMR DB00222(Glimepiride) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | no annotation | 13 | TYR B 24LEU B 54TYR B 55TRP B 86HIS B 117SER B 118MET B 120LEU B 122SER B 129VAL B 137ASN B 167TRP B 227PHE B 306 | GMR B 401 |
| 4ZFC_A_GCZA402 | 4zfc | GCZ DB01120(Gliclazide) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | PF00248(Aldo_ket_red) | 9 | TYR A 24LEU A 54TYR A 55TRP A 86HIS A 117MET A 120ASN A 167TRP A 227PHE A 306 | GCZ A 402 |
| 4ZFC_B_GCZB402 | 4zfc | GCZ DB01120(Gliclazide) | Homo sapiens | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3 | no annotation | 9 | TYR B 24LEU B 54TYR B 55TRP B 86HIS B 117MET B 120ASN B 167TRP B 227PHE B 306 | GCZ B 402 |