DRUG BINDING INTERFACES MAPPED TO 'BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (DHFR-TS)'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
3CL9_A_MTXA602 3cl9 MTX

DB00563
(Methotrexate) 		Trypanosoma cruzi BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		16 VAL A  26
ALA A  28
ILE A  41
ASP A  48
MET A  49
ARG A  53
THR A  80
SER A  83
ILE A  84
PRO A  85
PHE A  88
LEU A  91
PRO A  92
ARG A  94
TYR A 160
THR A 178
 MTX A 602