DRUG BINDING INTERFACES MAPPED TO 'BIFUNCTIONAL AAC/APH'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 4QC6_A_KANA201 | 4qc6 | KAN DB01172(Kanamycin) | Staphylococcuswarneri | BIFUNCTIONAL AAC/APH | PF13523(Acetyltransf_8) | 11 | TYR A 34GLY A 35HIS A 49TYR A 50GLU A 52TRP A 54GLN A 74ASP A 99ASP A 136HIS A 138GLU A 163 | KAN A 201 |
| 4QC6_B_KANB201 | 4qc6 | KAN DB01172(Kanamycin) | Staphylococcuswarneri | BIFUNCTIONAL AAC/APH | no annotation | 15 | TYR B 34GLY B 35HIS B 49TYR B 50GLU B 52TRP B 54ARG B 60GLN B 74LEU B 82ASP B 85TYR B 86ASP B 99ASP B 136HIS B 138GLU B 163 | KAN B 201 |
| 5IQB_A_KANA600 | 5iqb | KAN DB01172(Kanamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | PF01636(APH) | 12 | ASP A 374SER A 376ASN A 378ASP A 396TYR A 408GLU A 411SER A 413GLU A 415GLU A 416GLU A 445TYR A 448GLU A 451 | KAN A 600 |
| 5IQB_B_KANB600 | 5iqb | KAN DB01172(Kanamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 11 | ASP B 374SER B 376ASN B 378ASP B 396TYR B 408GLU B 411GLU B 415GLU B 416GLU B 445TYR B 448GLU B 451 | KAN B 600 |
| 5IQB_C_KANC600 | 5iqb | KAN DB01172(Kanamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 11 | ASP C 374SER C 376ASN C 378ASP C 396TYR C 408GLU C 411GLU C 415GLU C 416GLU C 445TYR C 448GLU C 451 | KAN C 600 |
| 5IQB_D_KAND600 | 5iqb | KAN DB01172(Kanamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 12 | ASP D 374SER D 376ASN D 378ASP D 396TYR D 408GLU D 411SER D 413GLU D 415GLU D 416GLU D 445TYR D 448GLU D 451 | KAN D 600 |
| 5IQC_A_51GA600 | 5iqc | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | PF01636(APH) | 10 | ASP A 374SER A 376ASP A 396TYR A 408GLU A 411GLU A 415GLU A 416GLU A 445TYR A 448GLU A 451 | 51G A 600 |
| 5IQC_B_51GB600 | 5iqc | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP B 374SER B 376ASP B 396TYR B 408GLU B 411GLU B 415GLU B 416GLU B 445TYR B 448GLU B 451 | 51G B 600 |
| 5IQC_C_51GC600 | 5iqc | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP C 374SER C 376ASP C 396TYR C 408GLU C 411GLU C 415GLU C 416GLU C 445TYR C 448GLU C 451 | 51G C 600 |
| 5IQC_D_51GD600 | 5iqc | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP D 374SER D 376ASP D 396TYR D 408GLU D 411GLU D 415GLU D 416GLU D 445TYR D 448GLU D 451 | 51G D 600 |
| 5IQD_A_RIOA600 | 5iqd | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | PF01636(APH) | 11 | ASP A 374SER A 376TYR A 408GLU A 411SER A 413GLU A 415GLU A 416VAL A 444GLU A 445TYR A 448GLU A 451 | RIO A 600 |
| 5IQD_B_RIOB600 | 5iqd | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 11 | ASP B 374SER B 376TYR B 408GLU B 411SER B 413GLU B 415GLU B 416VAL B 444GLU B 445TYR B 448GLU B 451 | RIO B 600 |
| 5IQD_C_RIOC600 | 5iqd | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 12 | ASP C 374SER C 376ASN C 378TYR C 408GLU C 411SER C 413GLU C 415GLU C 416VAL C 444GLU C 445TYR C 448GLU C 451 | RIO C 600 |
| 5IQD_D_RIOD600 | 5iqd | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 11 | ASP D 374SER D 376TYR D 408GLU D 411SER D 413GLU D 415GLU D 416VAL D 444GLU D 445TYR D 448GLU D 451 | RIO D 600 |
| 5IQE_A_NMYA600 | 5iqe | NMY DB00452(Framycetin)DB00994(Neomycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | PF01636(APH) | 11 | ASP A 374SER A 376ASP A 396TYR A 408GLU A 411SER A 413GLU A 415GLU A 416GLU A 445TYR A 448GLU A 451 | NMY A 600 |
| 5IQE_B_NMYB600 | 5iqe | NMY DB00452(Framycetin)DB00994(Neomycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP B 374SER B 376ASP B 396TYR B 408GLU B 411GLU B 415GLU B 416GLU B 445TYR B 448GLU B 451 | NMY B 600 |
| 5IQE_C_NMYC600 | 5iqe | NMY DB00452(Framycetin)DB00994(Neomycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 12 | ASP C 374SER C 376ASN C 378ASP C 396TYR C 408GLU C 411SER C 413GLU C 415GLU C 416GLU C 445TYR C 448GLU C 451 | NMY C 600 |
| 5IQE_D_NMYD600 | 5iqe | NMY DB00452(Framycetin)DB00994(Neomycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 12 | ASP D 374SER D 376ASN D 378ASP D 396TYR D 408GLU D 411SER D 413GLU D 415GLU D 416GLU D 445TYR D 448GLU D 451 | NMY D 600 |
| 5IQG_A_51GA600 | 5iqg | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | PF01636(APH) | 10 | ASP A 374SER A 376ASP A 396TYR A 408GLU A 411GLU A 415GLU A 416GLU A 445TYR A 448GLU A 451 | 51G A 600 |
| 5IQG_B_51GB600 | 5iqg | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP B 374SER B 376ASP B 396TYR B 408GLU B 411GLU B 415GLU B 416GLU B 445TYR B 448GLU B 451 | 51G B 600 |
| 5IQG_C_51GC600 | 5iqg | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP C 374SER C 376ASP C 396TYR C 408GLU C 411GLU C 415GLU C 416GLU C 445TYR C 448GLU C 451 | 51G C 600 |
| 5IQG_D_51GD600 | 5iqg | 51G DB00798(Gentamicin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | ASP D 374SER D 376ASP D 396TYR D 408GLU D 411GLU D 415GLU D 416GLU D 445TYR D 448GLU D 451 | 51G D 600 |
| 6C5U_A_RIOA600 | 6c5u | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | PF01636(APH) | 10 | ASP A 374SER A 376ASN A 378TYR A 408GLU A 411SER A 413GLU A 415GLU A 416GLU A 445TYR A 448 | RIO A 600 |
| 6C5U_B_RIOB600 | 6c5u | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 9 | ASP B 374SER B 376TYR B 408GLU B 411SER B 413GLU B 415GLU B 416GLU B 445TYR B 448 | RIO B 600 |
| 6C5U_D_RIOD600 | 6c5u | RIO DB03615(Ribostamycin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 10 | ASP D 374SER D 376ASN D 378TYR D 408GLU D 411SER D 413GLU D 415GLU D 416GLU D 445TYR D 448 | RIO D 600 |
| 6CGD_A_AKNA600 | 6cgd | AKN DB00479(Amikacin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 10 | GLY A 211TYR A 212ASP A 374ASP A 396TYR A 408GLU A 411VAL A 444GLU A 445TYR A 448GLU A 451 | AKN A 600 |
| 6CGD_D_AKND600 | 6cgd | AKN DB00479(Amikacin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | no annotation | 11 | ASP D 374SER D 376ASN D 378HIS D 379ASP D 396TYR D 408GLU D 411GLU D 415GLU D 416TYR D 448GLU D 451 | AKN D 600 |
| 6CGG_B_84GB600 | 6cgg | 84G DB06696(Arbekacin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 10 | ASP B 374SER B 376ASN B 378HIS B 379TYR B 408GLU B 411GLU B 415GLU B 416GLU B 445GLU B 451 | 84G B 600 |
| 6CGG_D_84GD600 | 6cgg | 84G DB06696(Arbekacin) | Staphylococcusaureus | BIFUNCTIONAL AAC/APH | None | 11 | ASP D 374SER D 376ASN D 378HIS D 379TYR D 408GLU D 411GLU D 415GLU D 416GLU D 445TYR D 448GLU D 451 | 84G D 600 |