DRUG BINDING INTERFACES MAPPED TO 'ANGIOTENSIN-CONVERTING ENZYME'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
2C6N_A_LPRA705 2c6n LPR

DB00722
(Lisinopril) 		Homo sapiens ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM 		PF01401
(Peptidase_M2) 		14 GLN A 259
HIS A 331
ALA A 332
SER A 333
GLN A 355
HIS A 361
GLU A 362
HIS A 365
GLU A 389
LYS A 489
HIS A 491
THR A 496
TYR A 498
TYR A 501
 LPR A 705
2C6N_B_LPRB705 2c6n LPR

DB00722
(Lisinopril) 		Homo sapiens ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM 		no annotation 15 GLN B 259
HIS B 331
ALA B 332
SER B 333
THR B 358
HIS B 361
GLU B 362
HIS B 365
GLU B 389
LYS B 489
PHE B 490
HIS B 491
THR B 496
TYR B 498
TYR B 501
 LPR B 705
4APJ_A_ACTA1635 4apj ACT

DB03166
(Acetic
acid) 		Gloydius
blomhoffii;
Homo sapiens 		ANGIOTENSIN-CONVERTI
NG ENZYME;
BRADYKININ-POTENTIAT
ING PEPTIDE B 		None
PF01401
(Peptidase_M2) 		6 PRO P  11
HIS A 383
HIS A 387
GLU A 411
ASP A 415
SER A 526
 ACT A1635
4C2P_A_X8ZA709 4c2p X8Z

DB01197
(Captopril) 		Homo sapiens ANGIOTENSIN-CONVERTI
NG ENZYME 		PF01401
(Peptidase_M2) 		11 GLN A 281
HIS A 353
HIS A 383
GLU A 384
HIS A 387
GLU A 411
PHE A 457
LYS A 511
HIS A 513
TYR A 520
TYR A 523
 X8Z A 709