DRUG BINDING INTERFACES MAPPED TO 'ALK TYROSINE KINASE RECEPTOR'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 3AOX_A_EMHA901 | 3aox | EMH DB11363(Alectinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 10 | ARG A1120LEU A1122ALA A1148LYS A1150VAL A1180LEU A1196LEU A1198MET A1199GLY A1202LEU A1256 | EMH A 901 |
| 4ANQ_A_VGHA9000 | 4anq | VGH DB08865(Crizotinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 9 | LEU A1122VAL A1130ALA A1148LEU A1196MET A1199GLY A1202LEU A1256ALA A1269ASP A1270 | VGH A9000 |
| 4ANS_A_VGHA9000 | 4ans | VGH DB08865(Crizotinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 9 | LEU A1122VAL A1130ALA A1148MET A1196MET A1199GLY A1202LEU A1256ALA A1269ASP A1270 | VGH A9000 |
| 4MKC_A_4MKA1503 | 4mkc | 4MK DB09063(Ceritinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 13 | LEU A1122GLY A1125VAL A1130ALA A1148LYS A1150LEU A1196LEU A1198MET A1199GLY A1202ASP A1203SER A1206LEU A1256ASP A1270 | 4MK A1503 |
| 5AAA_A_VGHA9000 | 5aaa | VGH DB08865(Crizotinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 9 | LEU A1122VAL A1130ALA A1148LEU A1196MET A1199GLY A1202LEU A1256GLY A1269ASP A1270 | VGH A9000 |
| 5AAB_A_VGHA9000 | 5aab | VGH DB08865(Crizotinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 10 | LEU A1122VAL A1130ALA A1148LYS A1150LEU A1196MET A1199GLY A1202LEU A1256GLY A1269ASP A1270 | VGH A9000 |
| 5AAC_A_VGHA9000 | 5aac | VGH DB08865(Crizotinib) | Homo sapiens | ALK TYROSINE KINASERECEPTOR | PF07714(Pkinase_Tyr) | 10 | LEU A1122VAL A1130ALA A1148LYS A1150LEU A1196MET A1199GLY A1202LEU A1256GLY A1269ASP A1270 | VGH A9000 |