DRUG BINDING INTERFACES MAPPED TO 'ALDOSE REDUCTASE'
List of Binding Interfaces (Click on the entry ID to view details of interfaces and pattern clusters) (Note that ASSAM search use only 3-12 residue containing patterns)| DrReposER ID | PDB | Ligand | Organism | Macromolecule | Pfam | Res. | Interface | HETATM |
|---|---|---|---|---|---|---|---|---|
| 2INE_A_PACA317 | 2ine | PAC DB09269(Phenylaceticacid) | Homo sapiens | ALDOSE REDUCTASE | PF00248(Aldo_ket_red) | 5 | TRP A 20VAL A 47TYR A 48HIS A 110TRP A 111 | PAC A 317 |
| 2ISF_A_PACA317 | 2isf | PAC DB09269(Phenylaceticacid) | Homo sapiens | ALDOSE REDUCTASE | PF00248(Aldo_ket_red) | 5 | TRP A 20VAL A 47TYR A 48HIS A 110TRP A 111 | PAC A 317 |
| 3RX3_A_SUZA317 | 3rx3 | SUZ DB00605(Sulindac) | Homo sapiens | ALDOSE REDUCTASE | PF00248(Aldo_ket_red) | 10 | TRP A 20VAL A 47TYR A 48HIS A 110TRP A 111PHE A 122TRP A 219CYS A 298LEU A 300SER A 302 | SUZ A 317 |
| 3S3G_A_TLTA317 | 3s3g | TLT DB00500(Tolmetin) | Homo sapiens | ALDOSE REDUCTASE | PF00248(Aldo_ket_red) | 7 | TRP A 20TYR A 48HIS A 110TRP A 111PHE A 122TRP A 219CYS A 298 | TLT A 317 |
| 3U2C_A_SUZA2001 | 3u2c | SUZ DB00605(Sulindac) | Homo sapiens | ALDOSE REDUCTASE | PF00248(Aldo_ket_red) | 9 | TRP A 20VAL A 47TYR A 48HIS A 110TRP A 111PHE A 122TRP A 219CYS A 298SER A 302 | SUZ A2001 |
| 3V35_A_NTIA317 | 3v35 | NTI DB00507(Nitazoxanide) | Homo sapiens | ALDOSE REDUCTASE | PF00248(Aldo_ket_red) | 8 | TRP A 20VAL A 47TRP A 79HIS A 110TRP A 111PHE A 122PRO A 218TRP A 219 | NTI A 317 |