DRUG BINDING INTERFACES MAPPED TO 'ALCOHOL DEHYDROGENASE'
List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
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Only hits with patterns containing 3-12 residues
DrReposER ID
PDB
Ligand
Organism
Macromolecule
Pfam
Res.
Interface
HETATM
1EE2_A_CHDA1150
1ee2
CHD
DB02659(CholicAcid)
Equus caballus
ALCOHOLDEHYDROGENASE
NonePF00107(ADH_zinc_N)PF08240(ADH_N)
15
CYS A 46SER A 48LEU A 57HIS A 67LEU A 110SER A 116MET A 117LEU A 140CYS A 173GLU B 283VAL A 293MET B 305LEU B 308SER B 309ILE A 317
CHD A1150
1EE2_B_CHDB1250
1ee2
CHD
DB02659(CholicAcid)
Equus caballus
ALCOHOLDEHYDROGENASE
NonePF00107(ADH_zinc_N)PF08240(ADH_N)
14
CYS B 46SER B 48LEU B 57HIS B 67LEU B 110SER B 116MET B 117LEU B 140CYS B 173VAL B 293MET A 305LEU A 308SER A 309ILE B 317
CHD B1250
2WEK_A_DIFA1373
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)
8
ASN A 75SER A 77PHE A 98MET A 124VAL A 155TYR A 275PHE A 304ASN A 306
DIF A1373
2WEK_A_DIFA1374
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)
5
TYR A 86MET A 124PRO A 126ASN A 306LEU A 309
DIF A1374
2WEK_A_DIFA1375
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)
3
LEU A 309TYR A 312GLN A 313
DIF A1375
2WEK_A_DIFA1376
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)
8
TYR A 161LEU A 164LYS A 165LEU A 192LYS A 195ALA A 196HIS A 318MET A 322
DIF A1376
2WEK_B_DIFB1373
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
no annotation
8
ASN B 75SER B 77PHE B 98MET B 124VAL B 155TYR B 275PHE B 304ASN B 306
DIF B1373
2WEK_B_DIFB1374
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
no annotation
6
TYR B 86MET B 124PRO B 126ILE B 139ASN B 306LEU B 309
DIF B1374
2WEK_B_DIFB1375
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
no annotation
5
TYR B 161LYS B 165LEU B 192LYS B 195HIS B 318
DIF B1375
2WEK_B_DIFB1376
2wek
DIF
DB00586(Diclofenac)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
no annotation
7
TYR B 224VAL B 248GLY B 250ALA B 251MET B 252LEU B 255SER B 273
DIF B1376
2X7H_A_PFNA1372
2x7h
PFN
DB00573(Fenoprofen)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)no annotation
11
TYR A 161LEU A 164LYS A 165LEU A 170LEU A 192LYS A 195THR B 277PRO B 278PRO B 283HIS A 318MET A 322
PFN A1372
2X7H_A_PFNA1374
2x7h
PFN
DB00573(Fenoprofen)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)
6
PRO A 144SER A 145LYS A 147GLU A 149TYR A 150CYS A 323
PFN A1374
2X7H_A_PFNA1375
2x7h
PFN
DB00573(Fenoprofen)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
PF00107(ADH_zinc_N)PF08240(ADH_N)
5
SER A 77TYR A 86PHE A 98VAL A 155TYR A 275
PFN A1375
2X7H_B_PFNB1372
2x7h
PFN
DB00573(Fenoprofen)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
no annotation
5
SER B 77TYR B 86PHE B 98VAL B 155TYR B 275
PFN B1372
2X7H_B_PFNB1374
2x7h
PFN
DB00573(Fenoprofen)
Homo sapiens
ZINC-BINDING ALCOHOLDEHYDROGENASEDOMAIN-CONTAININGPROTEIN 2
no annotation
4
TYR B 161LEU B 164LEU B 192HIS B 318
PFN B1374
3IV6_A_SAMA301
3iv6
SAM
DB00118(S-Adenosylmethionine)
Rhodobactersphaeroides
PUTATIVEZN-DEPENDENT ALCOHOLDEHYDROGENASE
None
15
ASN A 5TRP A 11PHE A 18PRO A 28GLY A 50SER A 52THR A 53ASP A 71PHE A 72SER A 73ASP A 95ILE A 96THR A 97ASP A 114LEU A 116
SAM A 301
3IV6_B_SAMB301
3iv6
SAM
DB00118(S-Adenosylmethionine)
Rhodobactersphaeroides
PUTATIVEZN-DEPENDENT ALCOHOLDEHYDROGENASE
None
12
TRP B 11PHE B 18GLY B 50SER B 52THR B 53ASP B 71PHE B 72ASP B 95ILE B 96ASP B 114LEU B 116ARG B 119
SAM B 301
3IV6_C_SAMC301
3iv6
SAM
DB00118(S-Adenosylmethionine)
Rhodobactersphaeroides
PUTATIVEZN-DEPENDENT ALCOHOLDEHYDROGENASE
None
15
TRP C 11PHE C 18ARG C 27PRO C 28GLY C 50SER C 52THR C 53ASP C 71PHE C 72SER C 73ASP C 95ILE C 96ASP C 114ARG C 115LEU C 116
SAM C 301
3IV6_D_SAMD301
3iv6
SAM
DB00118(S-Adenosylmethionine)
Rhodobactersphaeroides
PUTATIVEZN-DEPENDENT ALCOHOLDEHYDROGENASE
None
14
TRP D 11PHE D 18GLY D 50SER D 52THR D 53ASP D 71PHE D 72SER D 73ASP D 95ILE D 96ASP D 114ARG D 115LEU D 116ARG D 119
SAM D 301
[["1EE2_A_CHDA1150","1ee2","CHD","DB02659(Cholic Acid)","Equus caballus","ALCOHOL DEHYDROGENASE","None;PF00107(ADH_zinc_N);PF08240(ADH_N)",15,"CYS A 46;SER A 48;LEU A 57;HIS A 67;LEU A 110;SER A 116;MET A 117;LEU A 140;CYS A 173;GLU B 283;VAL A 293;MET B 305;LEU B 308;SER B 309;ILE A 317","CHD A1150\r"],["1EE2_B_CHDB1250","1ee2","CHD","DB02659(Cholic Acid)","Equus caballus","ALCOHOL DEHYDROGENASE","None;PF00107(ADH_zinc_N);PF08240(ADH_N)",14,"CYS B 46;SER B 48;LEU B 57;HIS B 67;LEU B 110;SER B 116;MET B 117;LEU B 140;CYS B 173;VAL B 293;MET A 305;LEU A 308;SER A 309;ILE B 317","CHD B1250\r"],["2WEK_A_DIFA1373","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N)",8,"ASN A 75;SER A 77;PHE A 98;MET A 124;VAL A 155;TYR A 275;PHE A 304;ASN A 306","DIF A1373\r"],["2WEK_A_DIFA1374","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N)",5,"TYR A 86;MET A 124;PRO A 126;ASN A 306;LEU A 309","DIF A1374\r"],["2WEK_A_DIFA1375","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N)",3,"LEU A 309;TYR A 312;GLN A 313","DIF A1375\r"],["2WEK_A_DIFA1376","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N)",8,"TYR A 161;LEU A 164;LYS A 165;LEU A 192;LYS A 195;ALA A 196;HIS A 318;MET A 322","DIF A1376\r"],["2WEK_B_DIFB1373","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","no annotation",8,"ASN B 75;SER B 77;PHE B 98;MET B 124;VAL B 155;TYR B 275;PHE B 304;ASN B 306","DIF B1373\r"],["2WEK_B_DIFB1374","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","no annotation",6,"TYR B 86;MET B 124;PRO B 126;ILE B 139;ASN B 306;LEU B 309","DIF B1374\r"],["2WEK_B_DIFB1375","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","no annotation",5,"TYR B 161;LYS B 165;LEU B 192;LYS B 195;HIS B 318","DIF B1375\r"],["2WEK_B_DIFB1376","2wek","DIF","DB00586(Diclofenac)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","no annotation",7,"TYR B 224;VAL B 248;GLY B 250;ALA B 251;MET B 252;LEU B 255;SER B 273","DIF B1376\r"],["2X7H_A_PFNA1372","2x7h","PFN","DB00573(Fenoprofen)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N);no annotation",11,"TYR A 161;LEU A 164;LYS A 165;LEU A 170;LEU A 192;LYS A 195;THR B 277;PRO B 278;PRO B 283;HIS A 318;MET A 322","PFN A1372\r"],["2X7H_A_PFNA1374","2x7h","PFN","DB00573(Fenoprofen)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N)",6,"PRO A 144;SER A 145;LYS A 147;GLU A 149;TYR A 150;CYS A 323","PFN A1374\r"],["2X7H_A_PFNA1375","2x7h","PFN","DB00573(Fenoprofen)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","PF00107(ADH_zinc_N);PF08240(ADH_N)",5,"SER A 77;TYR A 86;PHE A 98;VAL A 155;TYR A 275","PFN A1375\r"],["2X7H_B_PFNB1372","2x7h","PFN","DB00573(Fenoprofen)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","no annotation",5,"SER B 77;TYR B 86;PHE B 98;VAL B 155;TYR B 275","PFN B1372\r"],["2X7H_B_PFNB1374","2x7h","PFN","DB00573(Fenoprofen)","Homo sapiens","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","no annotation",4,"TYR B 161;LEU B 164;LEU B 192;HIS B 318","PFN B1374\r"],["3IV6_A_SAMA301","3iv6","SAM","DB00118(S-Adenosylmethionine)","Rhodobacter sphaeroides","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","None",15,"ASN A 5;TRP A 11;PHE A 18;PRO A 28;GLY A 50;SER A 52;THR A 53;ASP A 71;PHE A 72;SER A 73;ASP A 95;ILE A 96;THR A 97;ASP A 114;LEU A 116","SAM A 301\r"],["3IV6_B_SAMB301","3iv6","SAM","DB00118(S-Adenosylmethionine)","Rhodobacter sphaeroides","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","None",12,"TRP B 11;PHE B 18;GLY B 50;SER B 52;THR B 53;ASP B 71;PHE B 72;ASP B 95;ILE B 96;ASP B 114;LEU B 116;ARG B 119","SAM B 301\r"],["3IV6_C_SAMC301","3iv6","SAM","DB00118(S-Adenosylmethionine)","Rhodobacter sphaeroides","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","None",15,"TRP C 11;PHE C 18;ARG C 27;PRO C 28;GLY C 50;SER C 52;THR C 53;ASP C 71;PHE C 72;SER C 73;ASP C 95;ILE C 96;ASP C 114;ARG C 115;LEU C 116","SAM C 301\r"],["3IV6_D_SAMD301","3iv6","SAM","DB00118(S-Adenosylmethionine)","Rhodobacter sphaeroides","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","None",14,"TRP D 11;PHE D 18;GLY D 50;SER D 52;THR D 53;ASP D 71;PHE D 72;SER D 73;ASP D 95;ILE D 96;ASP D 114;ARG D 115;LEU D 116;ARG D 119","SAM D 301\r"]]