DRUG BINDING INTERFACES MAPPED TO 'ACTIN'

List of Binding Interfaces
(Click on the entry ID to view details of interfaces and pattern clusters)
(Note that ASSAM search use only 3-12 residue containing patterns)
Filter list by:
DrReposER ID PDB Ligand Organism Macromolecule Pfam Res. Interface HETATM
1A7Y_A_DVAA2 1a7y DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 4 THR A   1
PRO C   3
PRO A   3
THR A   7
DVA A   2
1A7Y_A_DVAA8 1a7y DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR A   1
THR A   7
PRO A   9
DVA A   8
1A7Y_B_DVAB2 1a7y DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR B   1
PRO B   3
THR B   7
DVA B   2
1A7Y_B_DVAB8 1a7y DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR B   1
THR B   7
PRO B   9
DVA B   8
1DSC_C_DVAC2 1dsc DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR C   1
PRO C   3
THR C   7
DVA C   2
1DSC_C_DVAC8 1dsc DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR C   1
THR C   7
PRO C   9
DVA C   8
1DSD_C_DVAC2 1dsd DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 4 THR C   1
PRO C   3
THR C   7
PRO C   9
DVA C   2
1DSD_C_DVAC8 1dsd DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 4 THR C   1
PRO C   3
THR C   7
PRO C   9
DVA C   8
1FJA_C_DVAC8 1fja DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR C   1
THR C   7
PRO C   9
DVA C   8
1FJA_D_DVAD8 1fja DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR D   1
THR D   7
PRO D   9
DVA D   8
1I3W_E_DVAE2 1i3w DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR E   1
PRO E   3
THR E   7
DVA E   2
1I3W_E_DVAE8 1i3w DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR E   1
THR E   7
PRO E   9
DVA E   8
1I3W_F_DVAF8 1i3w DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR F   1
THR F   7
PRO F   9
DVA F   8
1I3W_G_DVAG2 1i3w DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR G   1
PRO G   3
THR G   7
DVA G   2
1I3W_G_DVAG8 1i3w DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR G   1
THR G   7
PRO G   9
DVA G   8
1I3W_H_DVAH8 1i3w DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR H   1
THR H   7
PRO H   9
DVA H   8
1MNV_D_DVAD2 1mnv DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR D   1
PRO D   3
THR D   7
DVA D   2
1MNV_D_DVAD8 1mnv DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR D   1
THR D   7
PRO D   9
DVA D   8
1OVF_B_DVAB2 1ovf DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR B   1
PRO B   3
THR B   7
DVA B   2
1QFI_A_DVAA8 1qfi DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN X2 None 3 THR A   1
THR A   7
PRO A   9
DVA A   8
1QFI_B_DVAB8 1qfi DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN X2 None 3 THR B   1
THR B   7
PRO B   9
DVA B   8
1UNJ_F_DVAF2 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR F   1
PRO F   3
THR F   7
DVA F   2
1UNJ_F_DVAF8 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR F   1
THR F   7
PRO F   9
DVA F   8
1UNJ_L_DVAL2 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR L   1
PRO L   3
THR L   7
DVA L   2
1UNJ_L_DVAL8 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR L   1
THR L   7
PRO L   9
DVA L   8
1UNJ_R_DVAR2 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR R   1
PRO R   3
THR R   7
DVA R   2
1UNJ_R_DVAR8 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR R   1
THR R   7
PRO R   9
DVA R   8
1UNJ_W_DVAW8 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR W   1
THR W   7
PRO W   9
DVA W   8
1UNJ_X_DVAX2 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR X   1
PRO X   3
THR X   7
DVA X   2
1UNJ_X_DVAX8 1unj DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINO-ACTINOMYCIN
D
None 3 THR X   1
THR X   7
PRO X   9
DVA X   8
1UNM_E_DVAE2 1unm DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINOACTINOMYCIN D None 3 THR E   1
PRO E   3
THR E   7
DVA E   2
1UNM_E_DVAE8 1unm DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINOACTINOMYCIN D None 3 THR E   1
THR E   7
PRO E   9
DVA E   8
1UNM_F_DVAF2 1unm DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINOACTINOMYCIN D None 3 THR F   1
PRO F   3
THR F   7
DVA F   2
1UNM_F_DVAF8 1unm DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
7-AMINOACTINOMYCIN D None 3 THR F   1
THR F   7
PRO F   9
DVA F   8
209D_C_DVAC2 209d DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
N8-ACTINOMYCIN D None 3 THR C   1
PRO C   3
THR C   7
DVA C   2
209D_C_DVAC8 209d DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
N8-ACTINOMYCIN D None 3 THR C   1
THR C   7
PRO C   9
DVA C   8
2D55_C_DVAC2 2d55 DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR C   1
PRO C   3
PRO C   9
DVA C   2
2D55_C_DVAC8 2d55 DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 PRO C   3
THR C   7
PRO C   9
DVA C   8
316D_C_DVAC2 316d DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
8-FLUORO-ACTINOMYCIN
D
None 3 THR C   1
PRO C   3
THR C   7
DVA C   2
4C8B_A_0LIA1000 4c8b 0LI

DB08901
(Ponatinib)
Homo sapiens RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2
PF07714
(Pkinase_Tyr)
17 VAL A  32
ALA A  45
LYS A  47
GLU A  66
LEU A  70
ILE A  78
LEU A  79
ILE A  93
THR A  95
TYR A  97
MET A  98
HIS A 144
LEU A 153
ILE A 162
ALA A 163
ASP A 164
PHE A 165
0LI A1000
4C8B_B_0LIB1000 4c8b 0LI

DB08901
(Ponatinib)
Homo sapiens RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2
no annotation 15 ALA B  45
LYS B  47
GLU B  66
LEU B  70
ILE B  78
LEU B  79
THR B  95
TYR B  97
MET B  98
HIS B 144
LEU B 153
ILE B 162
ALA B 163
ASP B 164
PHE B 165
0LI B1000
4EAH_A_ACTA1002 4eah ACT

DB03166
(Acetic
acid)
Mus musculus;
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE;
FORMIN-LIKE PROTEIN
3
None
PF02181
(FH2)
5 GLN G 121
GLU G 125
THR G 126
THR E 612
ARG A 804
ACT A1002
4EAH_C_ACTC1002 4eah ACT

DB03166
(Acetic
acid)
Mus musculus;
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE;
FORMIN-LIKE PROTEIN
3
None 4 GLN H 121
GLU H 125
THR H 126
ARG C 804
ACT C1002
4EAH_D_ACTD401 4eah ACT

DB03166
(Acetic
acid)
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE
PF00022
(Actin)
4 PHE D  21
ASP D  25
ARG D  28
TRP D 340
ACT D 401
4EAH_E_ACTE1001 4eah ACT

DB03166
(Acetic
acid)
Mus musculus;
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE;
FORMIN-LIKE PROTEIN
3
None
PF00022
(Actin)
PF02181
(FH2)
4 GLN D 121
GLU D 125
THR A 612
ARG E 804
ACT E1001
4EAH_F_ACTF401 4eah ACT

DB03166
(Acetic
acid)
Mus musculus;
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE;
FORMIN-LIKE PROTEIN
3
None 4 GLN F 121
GLU F 125
THR C 612
ARG B 804
ACT F 401
4EAH_F_ACTF402 4eah ACT

DB03166
(Acetic
acid)
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE
None 3 PHE F  21
ASP F  25
ARG F  28
ACT F 402
4EAH_G_ACTG401 4eah ACT

DB03166
(Acetic
acid)
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE
None 3 PHE G  21
ASP G  25
ARG G  28
ACT G 401
4EAH_H_ACTH401 4eah ACT

DB03166
(Acetic
acid)
Oryctolagus
cuniculus
ACTIN, ALPHA
SKELETAL MUSCLE
None 4 PHE H  21
ASP H  25
ARG H  28
TRP H 340
ACT H 401
4HIV_D_DVAD2 4hiv DVA

DB00161
(L-
Valine)
Streptomyces
antibioticus
ACTINOMYCIN D None 3 THR D   1
PRO D   3
THR D   7
DVA D   2
4TNS_A_REAA201 4tns REA

DB00755
(Tretinoin)
Homo sapiens PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
NIMA-INTERACTING 1
PF00639
(Rotamase)
9 HIS A  59
LYS A  63
ARG A  68
ARG A  69
MET A 130
GLN A 131
PHE A 134
SER A 154
HIS A 157
REA A 201