SIMILAR PATTERNS OF AMINO ACIDS FOR 6MN1_B_LLLB302_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8w | LEUCOAGGLUTINATINGPHYTOHEMAGGLUTININ (Phaseolusvulgaris) |
PF00139(Lectin_legB) | 5 | ASP A 86GLY A 103ASP A 222THR A 220SER A 208 | None | 1.49A | 6mn1B-1g8wA:0.0 | 6mn1B-1g8wA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1e | DEOXY-D-MANNOSE-OCTULOSONATE 8-PHOSPHATEPHOSPHATASE (Haemophilusinfluenzae) |
PF08282(Hydrolase_3) | 5 | ASP A 111ASP A 16GLY A 106ASP A 90THR A 86 | CO A 201 ( 4.3A)NoneNoneGOL A2502 (-4.2A)None | 1.49A | 6mn1B-1k1eA:1.0 | 6mn1B-1k1eA:23.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lu2 | LECTIN (Vignaunguiculata) |
PF00139(Lectin_legB) | 5 | ASP A 85GLY A 102ASP A 223THR A 221SER A 209 | A2G A 254 (-2.7A)A2G A 254 (-3.7A)NoneNoneNone | 1.46A | 6mn1B-1lu2A:0.0 | 6mn1B-1lu2A:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n47 | ISOLECTIN B4 (Vicia villosa) |
PF00139(Lectin_legB) | 5 | ASP A 85GLY A 102ASP A 222THR A 220SER A 208 | TNR A1401 (-2.9A)TNR A1401 ( 3.9A)NoneNoneNone | 1.47A | 6mn1B-1n47A:0.0 | 6mn1B-1n47A:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bre | ATP-DEPENDENTMOLECULAR CHAPERONEHSP82 (Saccharomycescerevisiae) |
PF00183(HSP90)PF02518(HATPase_c) | 5 | ASP A 142ASP A 52ASP A 79THR A 171THR A 58 | NoneNoneKJ2 A1214 (-2.8A)KJ2 A1214 (-4.0A)None | 1.15A | 6mn1B-2breA:0.0 | 6mn1B-2breA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cg9 | ATP-DEPENDENTMOLECULAR CHAPERONEHSP82 (Saccharomycescerevisiae) |
PF00183(HSP90)PF02518(HATPase_c) | 5 | ASP A 142ASP A 52ASP A 79THR A 171THR A 58 | NoneNoneATP A1678 (-3.2A)ATP A1678 (-3.9A)None | 1.11A | 6mn1B-2cg9A:0.0 | 6mn1B-2cg9A:8.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oix | XANTHOMONAS OUTERPROTEIN D (Xanthomonaseuvesicatoria) |
PF02902(Peptidase_C48) | 5 | TRP A 410GLY A 471ASP A 497THR A 499THR A 476 | None | 1.49A | 6mn1B-2oixA:0.0 | 6mn1B-2oixA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 5 | ASP A 405GLY A 665TYR A 469ASP A 348THR A 349 | NoneNoneNoneMVL A 801 (-2.9A)None | 1.49A | 6mn1B-2wzsA:0.0 | 6mn1B-2wzsA:8.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcy | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Aliivibriofischeri) |
PF00275(EPSP_synthase) | 5 | ASP A 124GLY A 129ASP A 212THR A 213SER A 163 | UD1 A 501 (-3.4A)NoneNoneNoneUD1 A 501 (-2.4A) | 1.45A | 6mn1B-3vcyA:0.0 | 6mn1B-3vcyA:11.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5n | PUTATIVERHAMNOSIDASE (Streptomycesavermitilis) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 5 | TYR A 572ASP A 502GLY A 504ASP A 534THR A 536 | MPD A1207 (-4.6A)NoneNoneNoneNone | 1.38A | 6mn1B-3w5nA:undetectable | 6mn1B-3w5nA:5.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gwn | MEPRIN A SUBUNITBETA (Homo sapiens) |
PF00629(MAM)PF01400(Astacin) | 5 | ASP A 353GLY A 349ASP A 281THR A 324SER A 318 | None | 1.29A | 6mn1B-4gwnA:undetectable | 6mn1B-4gwnA:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lxo | FIBRONECTIN (Homo sapiens) |
PF00041(fn3) | 5 | ASP A1498TYR A1393ASP A1337THR A1344THR A1415 | None | 1.21A | 6mn1B-4lxoA:undetectable | 6mn1B-4lxoA:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p5h | CLAUDIN-2HEAT-LABILEENTEROTOXIN B CHAIN (Mus musculus;Clostridiumperfringens) |
no annotationPF03505(Clenterotox) | 5 | TYR A 139ASP A 45ASP 1 154GLY A 47THR A 107 | None | 1.29A | 6mn1B-4p5hA:undetectable | 6mn1B-4p5hA:16.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qnl | TAIL FIBER PROTEIN (Escherichiavirus G7C) |
no annotation | 5 | GLY A 670TYR A 634ASP A 503THR A 567SER A 665 | None | 1.36A | 6mn1B-4qnlA:undetectable | 6mn1B-4qnlA:6.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 5 | ASP A2360GLY A2294TYR A2432ASP A2487THR A2485 | NoneADP A4405 (-2.9A)NoneNoneNone | 1.49A | 6mn1B-4rh7A:undetectable | 6mn1B-4rh7A:2.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yga | VHH-1B7 (Vicugna pacos) |
PF07686(V-set) | 5 | TRP B 37GLY B 36TYR B 111THR B 100SER B 33 | None | 1.46A | 6mn1B-4ygaB:undetectable | 6mn1B-4ygaB:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0z | AURONE SYNTHASE (Coreopsisgrandiflora) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 5 | TYR A 128GLY A 277TYR A 283ASP A 321SER A 85 | None | 1.38A | 6mn1B-4z0zA:undetectable | 6mn1B-4z0zA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a6d | DNA POLYMERASESLIDING CLAMP (Thermococcusgammatolerans) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | ASP A 215GLY A 212ASP A 50THR A 240THR A 19 | None | 0.87A | 6mn1B-5a6dA:undetectable | 6mn1B-5a6dA:18.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ht0 | AMINOGLYCOSIDEACETYLTRANSFERASEHMB0005 (unculturedbacterium) |
PF02522(Antibiotic_NAT) | 5 | ASP A 64TRP A 65GLY A 115TYR A 138ASP A 213 | None | 1.26A | 6mn1B-5ht0A:43.8 | 6mn1B-5ht0A:98.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ht0 | AMINOGLYCOSIDEACETYLTRANSFERASEHMB0005 (unculturedbacterium) |
PF02522(Antibiotic_NAT) | 10 | TYR A 62ASP A 64TRP A 65ASP A 69GLY A 115TYR A 138ASP A 162THR A 163THR A 204SER A 205 | COA A 301 (-4.7A)NoneNoneNoneNoneNoneNoneCOA A 301 (-3.9A)NoneNone | 0.68A | 6mn1B-5ht0A:43.8 | 6mn1B-5ht0A:98.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ogl | UNDECAPRENYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEINGLYCOTRANSFERASE (Campylobacterlari) |
no annotation | 5 | TYR A 468ASP A 481GLY A 483TYR A 79ASP A 475 | 9UB A 803 (-4.7A)None9UB A 803 ( 3.8A)9UB A 803 (-4.4A) MN A 802 (-2.9A) | 1.44A | 6mn1B-5oglA:undetectable | 6mn1B-5oglA:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5or7 | CAPSID PROTEINCMRF35-LIKE MOLECULE1 (Norwalk virus;Mus musculus) |
no annotationno annotation | 5 | TYR C 34ASP C 98ASP A 410ASP C 51THR C 50 | None NA C 401 (-2.9A)NoneNone NA C 402 (-3.0A) | 1.46A | 6mn1B-5or7C:undetectable | 6mn1B-5or7C:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tuc | SUS TBC1D15 GAPDOMAIN (Sus scrofa) |
PF00566(RabGAP-TBC) | 5 | TYR A 435ASP A 397GLY A 438ASP A 421SER A 444 | None | 1.25A | 6mn1B-5tucA:undetectable | 6mn1B-5tucA:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uib | OXIDOREDUCTASEPROTEIN (Agrobacteriumtumefaciens) |
PF01408(GFO_IDH_MocA) | 5 | ASP A 185GLY A 316ASP A 304THR A 303SER A 313 | None | 1.27A | 6mn1B-5uibA:undetectable | 6mn1B-5uibA:14.02 |