SIMILAR PATTERNS OF AMINO ACIDS FOR 6JOG_A_ASCA202_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b04 | PROTEIN (DNA LIGASE) (Geobacillusstearothermophilus) |
PF01653(DNA_ligase_aden) | 3 | ASN A 18PRO A 60GLN A 62 | None | 0.94A | 6jogA-1b04A:undetectable | 6jogA-1b04A:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 3 | ASN A 174PRO A 179GLN A 5 | None | 0.91A | 6jogA-1cs1A:0.0 | 6jogA-1cs1A:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 3 | ASN A 376PRO A 282GLN A 284 | None | 0.72A | 6jogA-1fbwA:undetectable | 6jogA-1fbwA:13.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fdj | FRUCTOSE1,6-BISPHOSPHATEALDOLASE (Oryctolaguscuniculus) |
PF00274(Glycolytic) | 3 | ASN A1282PRO A1245GLN A1247 | None | 0.92A | 6jogA-1fdjA:0.9 | 6jogA-1fdjA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3g | CYCLOMALTODEXTRINASE (Flavobacteriumsp. 92) |
PF00128(Alpha-amylase)PF09087(Cyc-maltodext_N)PF10438(Cyc-maltodext_C) | 3 | ASN A 336PRO A 367GLN A 353 | None | 0.94A | 6jogA-1h3gA:0.0 | 6jogA-1h3gA:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hqs | ISOCITRATEDEHYDROGENASE (Bacillussubtilis) |
PF00180(Iso_dh) | 3 | ASN A 298PRO A 297GLN A 292 | None | 0.91A | 6jogA-1hqsA:0.9 | 6jogA-1hqsA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lba | T7 LYSOZYME (Escherichiavirus T7) |
PF01510(Amidase_2) | 3 | ASN A 94PRO A 23GLN A 25 | None | 0.76A | 6jogA-1lbaA:1.0 | 6jogA-1lbaA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mk2 | SMAD 3 (Homo sapiens) |
PF03166(MH2) | 3 | ASN A 344PRO A 402GLN A 404 | None | 0.90A | 6jogA-1mk2A:undetectable | 6jogA-1mk2A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qoz | ACETYL XYLANESTERASE (Trichodermareesei) |
PF01083(Cutinase) | 3 | ASN A 63PRO A 44GLN A 17 | NAG A 926 (-1.9A)NAG A 926 (-3.5A)None | 0.84A | 6jogA-1qozA:0.1 | 6jogA-1qozA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 3 | ASN A 232PRO A 130GLN A 132 | None | 0.92A | 6jogA-1r2fA:undetectable | 6jogA-1r2fA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rwu | HYPOTHETICAL UPF0250PROTEIN YBED (Escherichiacoli) |
PF04359(DUF493) | 3 | ASN A 63PRO A 40GLN A 36 | None | 0.85A | 6jogA-1rwuA:undetectable | 6jogA-1rwuA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u10 | PENICILLIN-INSENSITIVE MUREINENDOPEPTIDASE (Escherichiacoli) |
PF03411(Peptidase_M74) | 3 | ASN A 42PRO A 262GLN A 266 | None | 0.86A | 6jogA-1u10A:undetectable | 6jogA-1u10A:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wd3 | ALPHA-L-ARABINOFURANOSIDASE B (Aspergilluskawachii) |
PF05270(AbfB)PF09206(ArabFuran-catal) | 3 | ASN A 298PRO A 105GLN A 103 | None | 0.81A | 6jogA-1wd3A:undetectable | 6jogA-1wd3A:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2csg | PUTATIVE CYTOPLASMICPROTEIN (Salmonellaenterica) |
PF07350(DUF1479) | 3 | ASN A 371PRO A 366GLN A 159 | None | 0.91A | 6jogA-2csgA:undetectable | 6jogA-2csgA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7i | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 10 (Homo sapiens) |
PF00535(Glycos_transf_2)PF00652(Ricin_B_lectin) | 3 | ASN A 243PRO A 128GLN A 92 | None | 0.80A | 6jogA-2d7iA:5.0 | 6jogA-2d7iA:13.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dbn | HYPOTHETICAL PROTEINYBIU (Escherichiacoli) |
PF07350(DUF1479) | 3 | ASN A 371PRO A 366GLN A 159 | None | 0.94A | 6jogA-2dbnA:undetectable | 6jogA-2dbnA:16.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2guu | ODCASE (Plasmodiumvivax) |
PF00215(OMPdecase) | 3 | ASN A 152PRO A 88GLN A 93 | None | 0.87A | 6jogA-2guuA:undetectable | 6jogA-2guuA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ilr | FANCONI ANEMIA GROUPE PROTEIN (Homo sapiens) |
PF11510(FA_FANCE) | 3 | ASN A 359PRO A 321GLN A 323 | None | 0.84A | 6jogA-2ilrA:undetectable | 6jogA-2ilrA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m9k | RNA-BINDING PROTEINWITH MULTIPLESPLICING 2 (Homo sapiens) |
PF00076(RRM_1) | 3 | ASN A 97PRO A 39GLN A 68 | None | 0.87A | 6jogA-2m9kA:undetectable | 6jogA-2m9kA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nqa | CALPAIN 8 (Homo sapiens) |
PF00648(Peptidase_C2) | 3 | ASN A 174PRO A 85GLN A 132 | CSO A 82 ( 4.7A)CSO A 82 ( 4.1A)None | 0.93A | 6jogA-2nqaA:undetectable | 6jogA-2nqaA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pzk | PUTATIVE NUCLEOTIDESUGAR EPIMERASE/DEHYDRATASE (Bordetellabronchiseptica) |
PF01370(Epimerase) | 3 | ASN A 15PRO A 169GLN A 289 | None | 0.93A | 6jogA-2pzkA:3.6 | 6jogA-2pzkA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1c | ACYL-COENZYME (Penicilliumchrysogenum) |
PF03417(AAT) | 3 | ASN A 112PRO A 111GLN A 109 | None | 0.95A | 6jogA-2x1cA:undetectable | 6jogA-2x1cA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ygt | DELTA TOXIN (Clostridiumperfringens) |
PF07968(Leukocidin) | 3 | ASN A 136PRO A 111GLN A 161 | NoneNone ZN A1292 ( 4.8A) | 0.87A | 6jogA-2ygtA:undetectable | 6jogA-2ygtA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z69 | DNR PROTEIN (Pseudomonasaeruginosa) |
PF00027(cNMP_binding) | 3 | ASN A 123PRO A 19GLN A 12 | None | 0.86A | 6jogA-2z69A:undetectable | 6jogA-2z69A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a24 | ALPHA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 3 | ASN A 462PRO A 497GLN A 493 | None | 0.88A | 6jogA-3a24A:undetectable | 6jogA-3a24A:15.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axl | VALPHA 10 (Mus musculus) |
PF07686(V-set)PF09291(DUF1968) | 3 | ASN A 188PRO A 128GLN A 14 | None | 0.95A | 6jogA-3axlA:undetectable | 6jogA-3axlA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 3 | ASN A 71PRO A 73GLN A 74 | None | 0.82A | 6jogA-3b1bA:undetectable | 6jogA-3b1bA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 ALPHACHAIN (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF14710(Nitr_red_alph_N) | 3 | ASN A 545PRO A 224GLN A 229 | None | 0.94A | 6jogA-3egwA:undetectable | 6jogA-3egwA:8.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3feo | MBTDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF02820(MBT) | 3 | ASN A 53PRO A 116GLN A 120 | None | 0.59A | 6jogA-3feoA:undetectable | 6jogA-3feoA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gf7 | GLUTACONYL-COADECARBOXYLASESUBUNIT A ([Clostridium]symbiosum) |
PF01039(Carboxyl_trans) | 3 | ASN A 157PRO A 124GLN A 126 | None | 0.83A | 6jogA-3gf7A:undetectable | 6jogA-3gf7A:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gmj | PROTEIN MOTHERSAGAINST DPP (Drosophilamelanogaster) |
no annotation | 3 | ASN D 375PRO D 433GLN D 435 | None | 0.77A | 6jogA-3gmjD:undetectable | 6jogA-3gmjD:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0l | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A (Aquifexaeolicus) |
PF01425(Amidase) | 3 | ASN A 136PRO A 144GLN A 174 | None | 0.85A | 6jogA-3h0lA:undetectable | 6jogA-3h0lA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ijd | UNCHARACTERIZEDPROTEIN (Ruminiclostridiumthermocellum) |
PF02219(MTHFR) | 3 | ASN A 145PRO A 110GLN A 114 | None | 0.90A | 6jogA-3ijdA:undetectable | 6jogA-3ijdA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7y | ML43ML50 (Homo sapiens;Homo sapiens) |
no annotationPF01281(Ribosomal_L9_N) | 3 | ASN h 151PRO b 59GLN b 24 | None | 0.87A | 6jogA-3j7yh:undetectable | 6jogA-3j7yh:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k9t | PUTATIVE PEPTIDASE (Clostridiumacetobutylicum) |
PF09940(DUF2172)PF16221(HTH_47)PF16254(DUF4910) | 3 | ASN A 362PRO A 367GLN A 368 | None | 0.77A | 6jogA-3k9tA:undetectable | 6jogA-3k9tA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ldr | FRUCTOSYLTRANSFERASE (Aspergillusjaponicus) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 3 | ASN A 112PRO A 175GLN A 260 | None | 0.95A | 6jogA-3ldrA:undetectable | 6jogA-3ldrA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ml0 | PENICILLIN GACYLASE, BETASUBUNIT (Alcaligenesfaecalis) |
PF01804(Penicil_amidase) | 3 | ASN B 20PRO B 22GLN B 23 | None | 0.79A | 6jogA-3ml0B:undetectable | 6jogA-3ml0B:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3npf | PUTATIVEDIPEPTIDYL-PEPTIDASEVI (Bacteroidesovatus) |
PF00877(NLPC_P60) | 3 | ASN A 322PRO A 77GLN A 75 | GOL A 337 ( 4.1A)NoneNone | 0.72A | 6jogA-3npfA:undetectable | 6jogA-3npfA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o2u | NEDD8-CONJUGATINGENZYME UBC12 (Saccharomycescerevisiae) |
PF00179(UQ_con) | 3 | ASN A1017PRO A1023GLN A1022 | None | 0.91A | 6jogA-3o2uA:undetectable | 6jogA-3o2uA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oec | CARVEOLDEHYDROGENASE(MYTHA.01326.C,A0R518 HOMOLOG) (Mycolicibacteriumthermoresistibile) |
PF13561(adh_short_C2) | 3 | ASN A 62PRO A 61GLN A 59 | None | 0.82A | 6jogA-3oecA:3.9 | 6jogA-3oecA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozv | FLAVOHEMOGLOBIN (Cupriavidusnecator) |
no annotation | 3 | ASN B 238PRO B 233GLN B 231 | NoneNoneFAD B 405 (-3.8A) | 0.86A | 6jogA-3ozvB:3.9 | 6jogA-3ozvB:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3so5 | LEUCINE-RICH REPEATSANDIMMUNOGLOBULIN-LIKEDOMAINS PROTEIN 3 (Mus musculus) |
PF13927(Ig_3) | 3 | ASN A 585PRO A 499GLN A 500 | MLY A 498 ( 3.9A)MLY A 498 ( 2.6A)MLY A 498 ( 4.0A) | 0.91A | 6jogA-3so5A:undetectable | 6jogA-3so5A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u44 | ATP-DEPENDENTHELICASE/DEOXYRIBONUCLEASE SUBUNIT B (Bacillussubtilis) |
PF12705(PDDEXK_1) | 3 | ASN B 610PRO B 670GLN B 316 | None | 0.94A | 6jogA-3u44B:undetectable | 6jogA-3u44B:9.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1e | FLAGELLA BASAL-BODYPROTEIN (Vibrioalginolyticus) |
PF16538(FlgT_C)PF16539(FlgT_M)PF16548(FlgT_N) | 3 | ASN A 277PRO A 338GLN A 337 | None | 0.94A | 6jogA-3w1eA:undetectable | 6jogA-3w1eA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zif | PVIII (BovinemastadenovirusB) |
PF01310(Adeno_PVIII) | 3 | ASN R 52PRO R 8GLN R 25 | None | 0.82A | 6jogA-3zifR:undetectable | 6jogA-3zifR:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zn6 | VP16 (Thermus virusP23-77) |
no annotation | 3 | ASN B 53PRO B 128GLN B 126 | None | 0.88A | 6jogA-3zn6B:undetectable | 6jogA-3zn6B:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zxy | SUBTILISIN-LIKEPROTEIN (Prochlorondidemni) |
PF00082(Peptidase_S8) | 3 | ASN A 144PRO A 244GLN A 235 | None | 0.96A | 6jogA-3zxyA:undetectable | 6jogA-3zxyA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ag6 | TYPE IV SECRETORYPATHWAY VIRB4COMPONENTS-LIKEPROTEIN (Thermoanaerobacterpseudethanolicus) |
PF01935(DUF87) | 3 | ASN A 449PRO A 300GLN A 302 | None | 0.88A | 6jogA-4ag6A:undetectable | 6jogA-4ag6A:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akr | F-ACTIN-CAPPINGPROTEIN SUBUNITALPHAF-ACTIN-CAPPINGPROTEIN SUBUNIT BETA (Dictyosteliumdiscoideum;Dictyosteliumdiscoideum) |
PF01267(F-actin_cap_A)PF01115(F_actin_cap_B) | 3 | ASN A 199PRO B 18GLN B 20 | None | 0.93A | 6jogA-4akrA:undetectable | 6jogA-4akrA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eo4 | THREONINE--TRNALIGASE,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 3 | ASN A 64PRO A 347GLN A 349 | None | 0.95A | 6jogA-4eo4A:undetectable | 6jogA-4eo4A:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdh | CYTOCHROME P45011B2, MITOCHONDRIAL (Homo sapiens) |
PF00067(p450) | 3 | ASN A 281PRO A 283GLN A 284 | None | 0.82A | 6jogA-4fdhA:undetectable | 6jogA-4fdhA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h6w | N-TERMINALCYANOBACTIN PROTEASE (Planktothrixagardhii) |
PF00082(Peptidase_S8) | 3 | ASN A 147PRO A 247GLN A 238 | None | 0.89A | 6jogA-4h6wA:undetectable | 6jogA-4h6wA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hvl | MEMBRANE-ANCHOREDMYCOSIN MYCP1 (Mycolicibacteriumthermoresistibile) |
PF00082(Peptidase_S8) | 3 | ASN A 230PRO A 356GLN A 358 | None | 0.92A | 6jogA-4hvlA:undetectable | 6jogA-4hvlA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iuy | SHORT CHAINDEHYDROGENASE/REDUCTASE (Acinetobacterbaumannii) |
PF00106(adh_short) | 3 | ASN A 92PRO A 121GLN A 123 | None | 0.91A | 6jogA-4iuyA:3.7 | 6jogA-4iuyA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc5 | RHIE PROTEIN (Paraburkholderiarhizoxinica) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 3 | ASN A3380PRO A3445GLN A3391 | None | 0.90A | 6jogA-4kc5A:undetectable | 6jogA-4kc5A:10.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kg7 | PEPTIDASE S8 ANDS53, SUBTILISIN,KEXIN, SEDOLISIN (Mycolicibacteriumsmegmatis) |
PF00082(Peptidase_S8) | 3 | ASN A 383PRO A 301GLN A 278 | None | 0.93A | 6jogA-4kg7A:undetectable | 6jogA-4kg7A:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l9g | TRANSCRIPTIONALREGULATOR, PPSR (Rhodobactersphaeroides) |
PF13188(PAS_8) | 3 | ASN A 176PRO A 161GLN A 252 | None | 0.96A | 6jogA-4l9gA:undetectable | 6jogA-4l9gA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m5p | NADPH DEHYDROGENASE (Scheffersomycesstipitis) |
PF00724(Oxidored_FMN) | 3 | ASN A 152PRO A 131GLN A 74 | None | 0.82A | 6jogA-4m5pA:undetectable | 6jogA-4m5pA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n1a | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 3 | ASN A 976PRO A 833GLN A 834 | ATP A1401 ( 4.8A)ATP A1401 ( 4.7A)ATP A1401 (-3.6A) | 0.93A | 6jogA-4n1aA:undetectable | 6jogA-4n1aA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n3w | CREB-BINDING PROTEIN (Homo sapiens) |
PF00439(Bromodomain)PF06001(DUF902) | 3 | ASN A1163PRO A1258GLN A1259 | None | 0.76A | 6jogA-4n3wA:undetectable | 6jogA-4n3wA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 3 | ASN A1943PRO A1957GLN A1959 | None | 0.95A | 6jogA-4o9xA:undetectable | 6jogA-4o9xA:5.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pne | METHYLTRANSFERASE-LIKE PROTEIN (Saccharopolysporaspinosa) |
PF08241(Methyltransf_11) | 3 | ASN A 31PRO A 37GLN A 85 | None | 0.96A | 6jogA-4pneA:2.8 | 6jogA-4pneA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0k | DIPEPTIDYL-PEPTIDASEVI (Bacteroidesthetaiotaomicron) |
PF00877(NLPC_P60) | 3 | ASN A 322PRO A 77GLN A 75 | GOL A 403 (-3.6A)EDO A 406 ( 4.8A)None | 0.72A | 6jogA-4r0kA:undetectable | 6jogA-4r0kA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tpg | PROTON:OLIGOPEPTIDESYMPORTER POT FAMILY (Shewanellaoneidensis) |
PF00854(PTR2) | 3 | ASN A 305PRO A 456GLN A 458 | None | 0.96A | 6jogA-4tpgA:undetectable | 6jogA-4tpgA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u6d | CONSERVEDHYPOTHETICALPERIPLASMIC PROTEIN (Zobelliagalactanivorans) |
no annotation | 3 | ASN A 218PRO A 195GLN A 181 | NoneNone3DY A 521 (-3.2A) | 0.58A | 6jogA-4u6dA:undetectable | 6jogA-4u6dA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoo | LIPOTEICHOIC ACIDSYNTHASE (Listeriamonocytogenes) |
PF00884(Sulfatase) | 3 | ASN A 256PRO A 411GLN A 409 | None | 0.95A | 6jogA-4uooA:undetectable | 6jogA-4uooA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5p | CYTOCHROME P450HYDROXYLASE (Streptomycesatroolivaceus) |
PF00067(p450) | 3 | ASN A 247PRO A 392GLN A 393 | None | 0.93A | 6jogA-4z5pA:undetectable | 6jogA-4z5pA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z7l | CAS6B (Methanococcusmaripaludis) |
PF17262(DUF5328) | 3 | ASN A 39PRO A 50GLN A 51 | C C 29 ( 3.6A) G C 28 ( 4.4A)None | 0.66A | 6jogA-4z7lA:undetectable | 6jogA-4z7lA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a42 | UNCHARACTERIZEDLIPOPROTEIN YFHM (Escherichiacoli) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF11974(MG1) | 3 | ASN A 729PRO A 728GLN A 666 | None | 0.91A | 6jogA-5a42A:undetectable | 6jogA-5a42A:7.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5btb | AFR263CP (Eremotheciumgossypii) |
PF08652(RAI1) | 3 | ASN A 42PRO A 195GLN A 70 | None | 0.94A | 6jogA-5btbA:undetectable | 6jogA-5btbA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c7o | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Homo sapiens) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | ASN O 81PRO O 153GLN O 155 | NAD O 501 (-2.9A)NoneNone | 0.80A | 6jogA-5c7oO:3.0 | 6jogA-5c7oO:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e55 | CONTACTIN-6 (Mus musculus) |
PF00041(fn3) | 3 | ASN A 883PRO A 802GLN A 803 | None | 0.92A | 6jogA-5e55A:undetectable | 6jogA-5e55A:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fq6 | PUTATIVE LIPOPROTEIN (Bacteroidesthetaiotaomicron) |
PF12771(SusD-like_2) | 3 | ASN A 301PRO A 53GLN A 51 | None | 0.82A | 6jogA-5fq6A:undetectable | 6jogA-5fq6A:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fsa | CYP51 VARIANT1 (Candidaalbicans) |
PF00067(p450) | 3 | ASN A 237PRO A 124GLN A 250 | None | 0.93A | 6jogA-5fsaA:undetectable | 6jogA-5fsaA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 3 | ASN A 59PRO A 82GLN A 122 | None | 0.76A | 6jogA-5g5nA:undetectable | 6jogA-5g5nA:18.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5h16 | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Acinetobacterbaumannii) |
PF01467(CTP_transf_like) | 3 | ASN A 17PRO A 148GLN A 149 | None | 0.31A | 6jogA-5h16A:29.8 | 6jogA-5h16A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4e | MYOSIN-14,ALPHA-ACTININ A (Homo sapiens;Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF00435(Spectrin)PF02736(Myosin_N) | 3 | ASN A 619PRO A 418GLN A 428 | None | 0.92A | 6jogA-5i4eA:undetectable | 6jogA-5i4eA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j9g | GLYCERALDEHYDE-3-PDEHYDROGENASE (Lactobacillusacidophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | ASN A 264PRO A 298GLN A 300 | None | 0.78A | 6jogA-5j9gA:3.1 | 6jogA-5j9gA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jow | NON-REDUCING ENDALPHA-L-ARABINOFURANOSIDASE BOGH43A (Bacteroidesovatus) |
PF04616(Glyco_hydro_43) | 3 | ASN A 343PRO A 78GLN A 80 | None | 0.82A | 6jogA-5jowA:undetectable | 6jogA-5jowA:14.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k70 | PROTEIN SIDEKICK-2 (Mus musculus) |
PF07679(I-set)PF13927(Ig_3) | 3 | ASN A 364PRO A 288GLN A 289 | None | 0.92A | 6jogA-5k70A:undetectable | 6jogA-5k70A:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kha | GLUTAMINE-DEPENDENTNAD+ SYNTHETASE (Acinetobacterbaumannii) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 3 | ASN A 21PRO A 13GLN A 207 | None | 0.95A | 6jogA-5khaA:6.0 | 6jogA-5khaA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kzs | PUTATIVE CELLSURFACE PROTEIN,SIMILAR TOINTERNALIN PROTEINS (Listeriamonocytogenes) |
PF12354(Internalin_N)PF13855(LRR_8) | 3 | ASN A 237PRO A 258GLN A 294 | None | 0.91A | 6jogA-5kzsA:undetectable | 6jogA-5kzsA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpd | 26S PROTEASOMEREGULATORY SUBUNITRPN2 (Saccharomycescerevisiae) |
PF01851(PC_rep)PF13646(HEAT_2) | 3 | ASN N 900PRO N 876GLN N 878 | None | 0.89A | 6jogA-5mpdN:undetectable | 6jogA-5mpdN:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9j | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 14 (Schizosaccharomycespombe) |
PF08638(Med14) | 3 | ASN A 245PRO A 227GLN A 206 | None | 0.81A | 6jogA-5n9jA:undetectable | 6jogA-5n9jA:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofq | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 3 | ASN A 252PRO A 287GLN A 289 | NoneHEM A 501 ( 4.2A)None | 0.94A | 6jogA-5ofqA:undetectable | 6jogA-5ofqA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ovn | POL PROTEINPOL PROTEIN (Felineimmunodeficiencyvirus;Felineimmunodeficiencyvirus) |
no annotationno annotation | 3 | ASN B 135PRO A 94GLN A 268 | None | 0.84A | 6jogA-5ovnB:undetectable | 6jogA-5ovnB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uow | N-METHYL-D-ASPARTATERECEPTOR SUBUNITNR1-8A (Xenopus laevis) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 3 | ASN A 311PRO A 305GLN A 86 | None | 0.82A | 6jogA-5uowA:undetectable | 6jogA-5uowA:12.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v51 | PR-1 PROTEIN (Moniliophthoraperniciosa) |
PF00188(CAP) | 3 | ASN A 90PRO A 117GLN A 119 | NoneNoneSEY A 201 (-4.9A) | 0.88A | 6jogA-5v51A:undetectable | 6jogA-5v51A:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7a | ACYLOXYACYLHYDROLASE LARGESUBUNIT (Oryctolaguscuniculus) |
no annotation | 3 | ASN B 329PRO B 253GLN B 252 | None | 0.85A | 6jogA-5w7aB:undetectable | 6jogA-5w7aB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7c | ACYLOXYACYLHYDROLASE (Homo sapiens) |
no annotation | 3 | ASN C 330PRO C 254GLN C 253 | None | 0.91A | 6jogA-5w7cC:undetectable | 6jogA-5w7cC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | RNA POLYMERASE IISUBUNIT B12.5 (Komagataellaphaffii) |
PF13656(RNA_pol_L_2) | 3 | ASN K 29PRO K 83GLN K 85 | None | 0.90A | 6jogA-5xogK:undetectable | 6jogA-5xogK:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y0e | - (-) |
no annotation | 3 | ASN A 196PRO A 188GLN A 186 | None | 0.80A | 6jogA-5y0eA:undetectable | 6jogA-5y0eA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z5d | BETA-XYLOSIDASE (Geobacillusthermoleovorans) |
no annotation | 3 | ASN A 331PRO A 58GLN A 60 | None | 0.80A | 6jogA-5z5dA:undetectable | 6jogA-5z5dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zqz | TRIFUNCTIONAL ENZYMESUBUNIT ALPHA,MITOCHONDRIAL (Homo sapiens) |
no annotation | 3 | ASN A 352PRO A 357GLN A 358 | None | 0.82A | 6jogA-5zqzA:4.3 | 6jogA-5zqzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zqz | TRIFUNCTIONAL ENZYMESUBUNIT ALPHA,MITOCHONDRIAL (Homo sapiens) |
no annotation | 3 | ASN A 683PRO A 746GLN A 748 | None | 0.83A | 6jogA-5zqzA:4.3 | 6jogA-5zqzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6arr | ACETYL-COAACETYLTRANSFERASE (Aspergillusfumigatus) |
no annotation | 3 | ASN A 332PRO A 298GLN A 289 | None | 0.88A | 6jogA-6arrA:undetectable | 6jogA-6arrA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bf6 | INSULIN-DEGRADINGENZYME (Homo sapiens) |
no annotation | 3 | ASN A 783PRO A 678GLN A 680 | None | 0.86A | 6jogA-6bf6A:undetectable | 6jogA-6bf6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bn2 | ACETYL-COAACETYLTRANSFERASE (Elizabethkingiaanophelis) |
no annotation | 3 | ASN A 326PRO A 292GLN A 283 | NoneNoneGOL A 405 ( 3.9A) | 0.84A | 6jogA-6bn2A:undetectable | 6jogA-6bn2A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emk | SERINE/THREONINE-PROTEIN KINASE TOR2 (Saccharomycescerevisiae) |
no annotation | 3 | ASN A1541PRO A 858GLN A1583 | None | 0.92A | 6jogA-6emkA:undetectable | 6jogA-6emkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f45 | - (-) |
no annotation | 3 | ASN D 135PRO D 236GLN D 237 | None | 0.90A | 6jogA-6f45D:undetectable | 6jogA-6f45D:undetectable |