SIMILAR PATTERNS OF AMINO ACIDS FOR 6JOG_A_ASCA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1axk GLUXYN-1

(Bacillus
subtilis) 		PF00457
(Glyco_hydro_11)
PF00722
(Glyco_hydro_16) 		4 GLY A 242
THR A 243
SER A 333
SER A 332
 None
 0.86A 6jogA-1axkA:
undetectable		 6jogA-1axkA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1coz PROTEIN
(GLYCEROL-3-PHOSPHAT
E
CYTIDYLYLTRANSFERASE
)

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		4 GLY A   8
THR A   9
HIS A  17
SER A 118
 CTP  A 130 ( 3.8A)
CTP  A 130 (-4.3A)
CTP  A 130 (-3.7A)
CTP  A 130 (-3.9A)
 0.81A 6jogA-1cozA:
12.9		 6jogA-1cozA:
26.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		4 GLY A  83
THR A 151
SER A  58
SER A  59
 SAH  A 699 (-3.2A)
SAH  A 699 (-3.2A)
SAH  A 699 ( 4.9A)
SAH  A 699 ( 3.9A)
 1.10A 6jogA-1dl5A:
3.0		 6jogA-1dl5A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ex9 LACTONIZING LIPASE

(Pseudomonas
aeruginosa) 		PF00561
(Abhydrolase_1) 		4 GLY A  84
THR A  87
HIS A  14
SER A  48
 None
 1.11A 6jogA-1ex9A:
undetectable		 6jogA-1ex9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hix ENDO-1,4-BETA-XYLANA
SE

(Streptomyces
sp. S38) 		PF00457
(Glyco_hydro_11) 		4 GLY A  95
THR A  96
SER A 182
SER A 181
 None
 0.73A 6jogA-1hixA:
undetectable		 6jogA-1hixA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hy5 YERSINIA PESTIS
VIRULENCE PROTEIN
YOPE

(Yersinia pestis) 		PF03545
(YopE)
PF09020
(YopE_N) 		4 GLY A1182
THR A1183
HIS A1133
SER A1189
 None
 0.90A 6jogA-1hy5A:
undetectable		 6jogA-1hy5A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kaq NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		4 GLY A   9
THR A  10
HIS A  18
SER A 155
 DND  A 601 (-2.8A)
DND  A 601 (-3.1A)
DND  A 601 (-4.0A)
None
 0.27A 6jogA-1kaqA:
15.9		 6jogA-1kaqA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kaq NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		4 GLY A   9
THR A  10
SER A 155
SER A 156
 DND  A 601 (-2.8A)
DND  A 601 (-3.1A)
None
None
 0.98A 6jogA-1kaqA:
15.9		 6jogA-1kaqA:
24.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqo NICOTINAMIDE
MONONUCLEOTIDE
ADENYLYL TRANSFERASE

(Homo sapiens) 		PF01467
(CTP_transf_like) 		4 GLY A  15
HIS A  24
SER A 222
SER A 223
 DND  A 301 (-3.4A)
DND  A 301 ( 4.7A)
None
DND  A 301 ( 4.7A)
 0.42A 6jogA-1kqoA:
14.2		 6jogA-1kqoA:
24.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1o6b PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Bacillus
subtilis) 		PF01467
(CTP_transf_like) 		5 GLY A   9
HIS A  18
ARG A  91
SER A 128
SER A 129
 ADP  A 173 (-3.3A)
ADP  A 173 ( 3.9A)
None
PO4  A 170 (-4.6A)
PO4  A 170 (-3.4A)
 0.56A 6jogA-1o6bA:
25.3		 6jogA-1o6bA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Thermus
thermophilus) 		PF01467
(CTP_transf_like) 		4 GLY A   7
ARG A  91
SER A 128
SER A 129
 PNS  A1161 (-3.6A)
SO4  A1163 (-3.7A)
None
SO4  A1163 (-3.3A)
 0.71A 6jogA-1od6A:
24.6		 6jogA-1od6A:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1od6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Thermus
thermophilus) 		PF01467
(CTP_transf_like) 		4 GLY A   7
HIS A  16
SER A 128
SER A 129
 PNS  A1161 (-3.6A)
SO4  A1163 (-4.1A)
None
SO4  A1163 (-3.3A)
 0.35A 6jogA-1od6A:
24.6		 6jogA-1od6A:
49.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oed ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN

(Torpedo
marmorata) 		PF02932
(Neur_chan_memb) 		4 GLY B 450
THR B 451
ARG B 282
SER B 459
 None
 1.03A 6jogA-1oedB:
undetectable		 6jogA-1oedB:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ope SUCCINYL-COA:3-KETOA
CID-COENZYME A
TRANSFERASE

(Sus scrofa) 		PF01144
(CoA_trans) 		4 GLY A  23
ARG A 189
SER A 342
SER A 343
 None
 1.05A 6jogA-1opeA:
undetectable		 6jogA-1opeA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p4i ANTIBODY VARIABLE
LIGHT CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 GLY L  58
THR L  67
ARG L  70
SER L  79
 None
 0.98A 6jogA-1p4iL:
undetectable		 6jogA-1p4iL:
18.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Escherichia
coli) 		PF01467
(CTP_transf_like) 		5 GLY A   9
THR A  10
HIS A  18
SER A 128
SER A 129
 None
None
SO4  A1161 (-4.2A)
SO4  A1161 (-4.8A)
SO4  A1161 (-3.0A)
 0.44A 6jogA-1qjcA:
24.6		 6jogA-1qjcA:
60.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6x RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE

(Thermotoga
maritima) 		PF01687
(Flavokinase)
PF06574
(FAD_syn) 		4 GLY A   6
HIS A  15
SER A 136
SER A 137
 None
 0.73A 6jogA-1t6xA:
8.6		 6jogA-1t6xA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1te1 ENDO-1,4-XYLANASE

(Talaromyces
funiculosus) 		PF00457
(Glyco_hydro_11) 		4 GLY B  93
THR B  94
SER B 181
SER B 180
 EDO  B 208 ( 4.5A)
None
None
None
 0.84A 6jogA-1te1B:
undetectable		 6jogA-1te1B:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjr BX1

(Zea mays) 		PF00290
(Trp_syntA) 		4 GLY A 160
THR A 161
ARG A 155
SER A 152
 None
 0.90A 6jogA-1tjrA:
undetectable		 6jogA-1tjrA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uz4 MAN5A

(Cellvibrio
mixtus) 		PF00150
(Cellulase) 		4 GLY A 257
HIS A 272
SER A 252
SER A 253
 None
 0.71A 6jogA-1uz4A:
2.4		 6jogA-1uz4A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		4 GLY A 125
ARG A 498
SER A 495
SER A  50
 None
 1.09A 6jogA-1v4gA:
undetectable		 6jogA-1v4gA:
16.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vlh PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Thermotoga
maritima) 		PF01467
(CTP_transf_like) 		4 GLY A   7
HIS A  16
SER A 126
SER A 127
 PNS  A 200 (-3.3A)
None
None
None
 0.27A 6jogA-1vlhA:
24.7		 6jogA-1vlhA:
43.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wac P2 PROTEIN

(Pseudomonas
virus phi6) 		PF00680
(RdRP_1) 		4 GLY A 630
THR A 631
HIS A 303
SER A 296
 None
 1.02A 6jogA-1wacA:
undetectable		 6jogA-1wacA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x4g NUCLEOLYSIN TIAR

(Homo sapiens) 		PF00076
(RRM_1) 		4 THR A  27
HIS A  71
SER A  22
SER A  21
 None
 0.93A 6jogA-1x4gA:
undetectable		 6jogA-1x4gA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yna ENDO-1,4-BETA-XYLANA
SE

(Thermomyces
lanuginosus) 		PF00457
(Glyco_hydro_11) 		4 GLY A  94
THR A  95
SER A 183
SER A 182
 None
 0.98A 6jogA-1ynaA:
undetectable		 6jogA-1ynaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ys2 LIPASE

(Burkholderia
cepacia) 		PF00561
(Abhydrolase_1) 		4 GLY X  89
THR X  92
HIS X  15
SER X  50
 None
 1.01A 6jogA-1ys2X:
undetectable		 6jogA-1ys2X:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yul PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 GLY A  10
THR A  11
HIS A  19
SER A 178
 None
None
CIT  A 230 (-3.8A)
CIT  A 230 (-3.3A)
 0.54A 6jogA-1yulA:
14.4		 6jogA-1yulA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdz MEXICAIN

(Jacaratia
mexicana) 		PF00112
(Peptidase_C1) 		4 GLY A 201
THR A 204
SER A 131
SER A 206
 None
 1.01A 6jogA-2bdzA:
undetectable		 6jogA-2bdzA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dck XYLANASE J

(Bacillus sp.
41M-1) 		PF00457
(Glyco_hydro_11)
PF03422
(CBM_6) 		4 GLY A 101
THR A 102
SER A 188
SER A 187
 None
 0.87A 6jogA-2dckA:
undetectable		 6jogA-2dckA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h29 PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Staphylococcus
aureus) 		PF01467
(CTP_transf_like) 		4 GLY A   9
HIS A  18
SER A 155
SER A 156
 DND  A 998 (-3.2A)
DND  A 998 ( 4.6A)
None
None
 0.20A 6jogA-2h29A:
15.4		 6jogA-2h29A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hru PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE II

(Thermotoga
maritima) 		PF00586
(AIRS)
PF02769
(AIRS_C)
PF16904
(PurL_C) 		4 GLY A  89
THR A  86
ARG A 284
SER A 281
 None
 1.07A 6jogA-2hruA:
undetectable		 6jogA-2hruA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjo BIFUNCTIONAL NMN
ADENYLYLTRANSFERASE/
NUDIX HYDROLASE

(Synechocystis
sp. PCC 6803) 		PF00293
(NUDIX)
PF01467
(CTP_transf_like) 		4 GLY A  12
HIS A  21
SER A 138
SER A 139
 NAD  A 601 (-3.3A)
NAD  A 601 (-4.5A)
POP  A 701 (-2.9A)
POP  A 701 (-3.9A)
 0.62A 6jogA-2qjoA:
14.8		 6jogA-2qjoA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtn NICOTINATE
(NICOTINAMIDE)
NUCLEOTIDE
ADENYLYLTRANSFERASE

(Bacillus
anthracis) 		PF01467
(CTP_transf_like) 		4 GLY A   8
HIS A  18
SER A 155
SER A 156
 None
None
GOL  A 191 (-3.8A)
GOL  A 191 (-4.1A)
 0.80A 6jogA-2qtnA:
14.7		 6jogA-2qtnA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtn NICOTINATE
(NICOTINAMIDE)
NUCLEOTIDE
ADENYLYLTRANSFERASE

(Bacillus
anthracis) 		PF01467
(CTP_transf_like) 		5 GLY A   9
THR A  10
HIS A  18
SER A 155
SER A 156
 GOL  A 191 ( 4.0A)
GOL  A 191 (-3.2A)
None
GOL  A 191 (-3.8A)
GOL  A 191 (-4.1A)
 0.87A 6jogA-2qtnA:
14.7		 6jogA-2qtnA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qua EXTRACELLULAR LIPASE

(Serratia
marcescens) 		no annotation 4 GLY A 567
THR A 568
HIS A   0
SER A 572
 None
 0.90A 6jogA-2quaA:
undetectable		 6jogA-2quaA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8r GLYCOSYL HYDROLASE

(Aspergillus
fumigatus) 		PF01183
(Glyco_hydro_25) 		4 GLY A  79
THR A  81
HIS A  70
ARG A  73
 None
 0.92A 6jogA-2x8rA:
undetectable		 6jogA-2x8rA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zk9 PROTEIN-GLUTAMINASE

(Chryseobacterium
proteolyticum) 		no annotation 4 GLY X  74
THR X  75
ARG X  36
SER X 170
 None
 1.07A 6jogA-2zk9X:
undetectable		 6jogA-2zk9X:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a55 PROTEIN-GLUTAMINASE

(Chryseobacterium
proteolyticum) 		no annotation 4 GLY A 188
THR A 189
ARG A 150
SER A 284
 None
 1.09A 6jogA-3a55A:
undetectable		 6jogA-3a55A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cia COLD-ACTIVE
AMINOPEPTIDASE

(Colwellia
psychrerythraea) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		4 GLY A 148
THR A 147
HIS A 617
ARG A 585
 None
 0.93A 6jogA-3ciaA:
undetectable		 6jogA-3ciaA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2z UNCHARACTERIZED
PROTEIN BF3579

(Bacteroides
fragilis) 		PF00754
(F5_F8_type_C) 		4 GLY A 424
THR A 425
ARG A 364
SER A 333
 None
 1.05A 6jogA-3f2zA:
undetectable		 6jogA-3f2zA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpf MUCONATE
CYCLOISOMERASE

(Oceanobacillus
iheyensis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLY A 295
THR A 296
HIS A 246
SER A 195
 None
GAE  A 411 (-4.6A)
MG  A 401 ( 3.3A)
GAE  A 411 ( 4.8A)
 1.00A 6jogA-3hpfA:
undetectable		 6jogA-3hpfA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcm U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP4

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 GLY B 309
HIS B 306
SER B 331
SER B 324
 None
 1.06A 6jogA-3jcmB:
undetectable		 6jogA-3jcmB:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kkj AMINE OXIDASE,
FLAVIN-CONTAINING

(Pseudomonas
syringae group
genomosp. 3) 		PF01593
(Amino_oxidase)
PF13450
(NAD_binding_8) 		4 GLY A   9
THR A  10
SER A 125
SER A  34
 FAD  A 401 (-3.6A)
None
None
FAD  A 401 (-3.4A)
 1.08A 6jogA-3kkjA:
2.7		 6jogA-3kkjA:
20.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Yersinia pestis) 		PF01467
(CTP_transf_like) 		5 GLY A   9
THR A  10
HIS A  18
SER A 128
SER A 129
 None
 0.60A 6jogA-3l93A:
26.5		 6jogA-3l93A:
56.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lb9 ENDO-1,4-BETA-XYLANA
SE

(Bacillus
circulans) 		PF00457
(Glyco_hydro_11) 		4 GLY A 151
THR A 152
SER A  56
SER A  55
 None
 0.83A 6jogA-3lb9A:
undetectable		 6jogA-3lb9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mf9 ENDO-1,4-BETA-XYLANA
SE

(Thermopolyspora
flexuosa) 		PF00457
(Glyco_hydro_11) 		4 GLY A  96
THR A  97
SER A 182
SER A 181
 None
 0.89A 6jogA-3mf9A:
undetectable		 6jogA-3mf9A:
17.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nbk PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		5 GLY A   8
HIS A  17
ARG A  90
SER A 126
SER A 127
 PNS  A 200 (-3.2A)
None
None
None
None
 0.66A 6jogA-3nbkA:
24.7		 6jogA-3nbkA:
38.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Enterococcus
faecalis) 		PF01467
(CTP_transf_like) 		4 GLY A   9
HIS A  18
SER A 129
SER A 130
 ATP  A 961 ( 3.7A)
ATP  A 961 (-4.3A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.35A 6jogA-3nd6A:
23.9		 6jogA-3nd6A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Enterococcus
faecalis) 		PF01467
(CTP_transf_like) 		4 HIS A  18
ARG A  92
SER A 129
SER A 130
 ATP  A 961 (-4.3A)
ATP  A 961 (-3.5A)
ATP  A 961 (-3.4A)
ATP  A 961 (-3.6A)
 0.86A 6jogA-3nd6A:
23.9		 6jogA-3nd6A:
35.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nv7 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Helicobacter
pylori) 		PF01467
(CTP_transf_like) 		4 GLY A   9
THR A  10
HIS A  18
ARG A  91
 ACY  A 162 (-3.6A)
SO4  A 160 (-4.0A)
SO4  A 158 ( 4.1A)
SO4  A 158 ( 3.8A)
 1.10A 6jogA-3nv7A:
12.0		 6jogA-3nv7A:
42.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oml PEROXISOMAL
MULTIFUNCTIONAL
ENZYME TYPE 2,
CG3415

(Drosophila
melanogaster) 		PF00106
(adh_short)
PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		4 GLY A 519
THR A 522
ARG A 548
SER A 585
 None
 0.79A 6jogA-3omlA:
undetectable		 6jogA-3omlA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op1 MACROLIDE-EFFLUX
PROTEIN

(Streptococcus
pneumoniae) 		PF01687
(Flavokinase)
PF06574
(FAD_syn) 		4 GLY A  24
HIS A  33
SER A 163
SER A 164
 GOL  A 318 (-3.6A)
SO4  A 311 (-4.3A)
SO4  A 311 (-4.8A)
SO4  A 311 (-2.9A)
 0.68A 6jogA-3op1A:
8.4		 6jogA-3op1A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ow8 WD REPEAT-CONTAINING
PROTEIN 61

(Homo sapiens) 		PF00400
(WD40) 		4 GLY A 124
THR A 123
SER A  83
SER A  82
 None
 0.81A 6jogA-3ow8A:
undetectable		 6jogA-3ow8A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvl MYOSIN VIIA ISOFORM
1

(Mus musculus) 		PF00784
(MyTH4) 		4 GLY A1159
HIS A1155
SER A1245
SER A1324
 None
 1.02A 6jogA-3pvlA:
undetectable		 6jogA-3pvlA:
13.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pxu PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Burkholderia
pseudomallei) 		PF01467
(CTP_transf_like) 		4 GLY A   8
THR A   9
HIS A  17
SER A 127
 COD  A 201 (-3.1A)
COD  A 201 (-3.6A)
COD  A 201 (-4.3A)
SO4  A 205 (-3.0A)
 0.79A 6jogA-3pxuA:
25.4		 6jogA-3pxuA:
52.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s36 VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		PF00047
(ig) 		4 THR X 298
HIS X 267
SER X 265
SER X 264
 None
 0.96A 6jogA-3s36X:
undetectable		 6jogA-3s36X:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s6h N-ACETYLGLUTAMATE
KINASE /
N-ACETYLGLUTAMATE
SYNTHASE

(Maricaulis
maris) 		PF00696
(AA_kinase)
PF04768
(NAT) 		4 GLY A 285
THR A 269
ARG A 289
SER A 265
 None
 1.09A 6jogA-3s6hA:
5.1		 6jogA-3s6hA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdo NITRILOTRIACETATE
MONOOXYGENASE

(Burkholderia
pseudomallei) 		PF00296
(Bac_luciferase) 		4 GLY A 133
THR A 132
SER A  97
SER A  96
 None
 0.95A 6jogA-3sdoA:
undetectable		 6jogA-3sdoA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tnx PAPAIN

(Carica papaya) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 GLY A 308
THR A 311
SER A 238
SER A 313
 None
 1.05A 6jogA-3tnxA:
undetectable		 6jogA-3tnxA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v7i PUTATIVE POLYKETIDE
SYNTHASE

(Streptomyces
coelicolor) 		PF00195
(Chal_sti_synt_N) 		4 GLY A 315
THR A 316
ARG A 347
SER A 344
 None
 1.10A 6jogA-3v7iA:
undetectable		 6jogA-3v7iA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3viu PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE 2

(Thermus
thermophilus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 GLY A 104
THR A 101
ARG A 307
SER A 304
 None
 1.08A 6jogA-3viuA:
undetectable		 6jogA-3viuA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vzm ENDO-1,4-BETA-XYLANA
SE

(Bacillus
circulans) 		PF00457
(Glyco_hydro_11) 		4 GLY A  86
THR A  87
SER A 177
SER A 176
 None
 0.90A 6jogA-3vzmA:
undetectable		 6jogA-3vzmA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0l GLUCOKINASE
REGULATORY PROTEIN

(Xenopus laevis) 		no annotation 4 GLY B 108
THR B 109
SER B 257
SER B 258
 F6R  B 701 (-3.6A)
F6R  B 701 (-3.7A)
F6R  B 701 ( 4.7A)
F6R  B 701 (-3.4A)
 1.01A 6jogA-3w0lB:
undetectable		 6jogA-3w0lB:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wla OXIDIZED POLYVINYL
ALCOHOL HYDROLASE

(Sphingopyxis
sp. 113P3) 		no annotation 4 GLY A  49
THR A  50
HIS A 279
SER A 249
 SO4  A 901 ( 3.7A)
SO4  A 901 (-3.8A)
SO4  A 901 ( 4.4A)
None
 1.08A 6jogA-3wlaA:
undetectable		 6jogA-3wlaA:
18.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		5 GLY A   8
THR A   9
HIS A  17
ARG A  90
SER A 127
 ACO  A 201 (-3.2A)
ACO  A 201 (-3.9A)
ACO  A 201 (-4.1A)
ACO  A 201 (-4.4A)
ACO  A 201 (-3.0A)
 0.86A 6jogA-3x1jA:
26.1		 6jogA-3x1jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		5 GLY A   8
THR A   9
HIS A  17
SER A 127
SER A 128
 ACO  A 201 (-3.2A)
ACO  A 201 (-3.9A)
ACO  A 201 (-4.1A)
ACO  A 201 (-3.0A)
ACO  A 201 (-3.1A)
 0.82A 6jogA-3x1jA:
26.1		 6jogA-3x1jA:
67.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfc CHROMOSOME-ASSOCIATE
D KINESIN KIF4

(Mus musculus) 		PF00225
(Kinesin) 		4 GLY A 261
ARG A 199
SER A 211
SER A 210
 None
None
MG  A 500 ( 2.1A)
ANP  A 501 (-2.6A)
 1.09A 6jogA-3zfcA:
undetectable		 6jogA-3zfcA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zse ENDO-1,4-BETA-XYLANA
SE

(Thermobifida
fusca) 		PF00457
(Glyco_hydro_11) 		4 GLY A 135
THR A 136
SER A 221
SER A 220
 None
 0.81A 6jogA-3zseA:
undetectable		 6jogA-3zseA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0k DNA DAMAGE-BINDING
PROTEIN 2

(Danio rerio) 		PF00400
(WD40) 		4 GLY D 255
THR D 254
SER D 212
SER D 211
 None
 0.95A 6jogA-4a0kD:
undetectable		 6jogA-4a0kD:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b6s 3-DEHYDROQUINATE
DEHYDRATASE

(Helicobacter
pylori) 		PF01220
(DHquinase_II) 		4 GLY A 119
THR A 118
HIS A 102
ARG A 113
 None
None
2HN  A 200 (-4.0A)
2HN  A 200 (-3.7A)
 1.07A 6jogA-4b6sA:
undetectable		 6jogA-4b6sA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c6o CAD PROTEIN

(Homo sapiens) 		PF01979
(Amidohydro_1) 		5 GLY A1543
THR A1544
HIS A1577
SER A1539
SER A1538
 None
 1.08A 6jogA-4c6oA:
undetectable		 6jogA-4c6oA:
18.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f3r PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Coxiella
burnetii) 		PF01467
(CTP_transf_like) 		5 GLY A   9
THR A  10
HIS A  18
ARG A  90
SER A 127
 None
 0.40A 6jogA-4f3rA:
23.2		 6jogA-4f3rA:
48.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h4c 4-HYDROXY-3-METHYLBU
T-2-ENYL DIPHOSPHATE
REDUCTASE

(Escherichia
coli) 		PF02401
(LYTB) 		4 THR A 167
HIS A 124
SER A 225
SER A 226
 SF4  A 401 (-3.5A)
10D  A 402 (-4.0A)
10D  A 402 (-2.4A)
10D  A 402 (-4.3A)
 1.10A 6jogA-4h4cA:
undetectable		 6jogA-4h4cA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hk9 ENDO-1,4-BETA-XYLANA
SE 2

(Trichoderma
reesei) 		PF00457
(Glyco_hydro_11) 		4 GLY A  94
THR A  95
SER A 182
SER A 181
 None
 0.84A 6jogA-4hk9A:
undetectable		 6jogA-4hk9A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixl XYLANASE

(Bacillus sp.
(in: Bacteria)) 		PF00457
(Glyco_hydro_11) 		4 GLY A 101
THR A 102
SER A 188
SER A 187
 None
 0.83A 6jogA-4ixlA:
undetectable		 6jogA-4ixlA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kp9 PAPAIN

(Carica papaya) 		PF00112
(Peptidase_C1) 		4 GLY A 201
THR A 204
SER A 131
SER A 206
 None
 1.05A 6jogA-4kp9A:
undetectable		 6jogA-4kp9A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg8 PRE-MRNA-PROCESSING
FACTOR 19

(Homo sapiens) 		PF00400
(WD40) 		4 GLY A 368
THR A 367
SER A 325
SER A 324
 None
 1.08A 6jogA-4lg8A:
undetectable		 6jogA-4lg8A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lvo SUBTILISIN-LIKE
SERINE PROTEASE
SUBTILISIN-LIKE
SERINE PROTEASE

(Plasmodium
falciparum;
Plasmodium
falciparum) 		PF00082
(Peptidase_S8)
no annotation 		4 GLY A 604
THR A 605
HIS A 428
SER P 215
 None
 1.00A 6jogA-4lvoA:
undetectable		 6jogA-4lvoA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mgg MUCONATE LACTONIZING
ENZYME

(Labrenzia
aggregata) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLY A 197
THR A 196
ARG A 200
SER A 227
 MG  A 403 (-4.0A)
None
None
None
 0.98A 6jogA-4mggA:
undetectable		 6jogA-4mggA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mow GLUCOSE
1-DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF13561
(adh_short_C2) 		4 GLY A 166
THR A 165
ARG A 178
SER A 135
 None
 0.87A 6jogA-4mowA:
3.6		 6jogA-4mowA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0i GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT B,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF02934
(GatB_N) 		4 GLY B 223
THR B 222
SER B  52
SER B  55
 None
 1.02A 6jogA-4n0iB:
undetectable		 6jogA-4n0iB:
17.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4nat PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Staphylococcus
aureus) 		PF01467
(CTP_transf_like) 		4 GLY A  10
HIS A  19
SER A 129
SER A 130
 ADP  A 203 (-3.3A)
ADP  A 203 (-4.0A)
None
ADP  A 203 ( 4.6A)
 0.39A 6jogA-4natA:
24.5		 6jogA-4natA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r0n PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		5 GLY A   8
HIS A  17
ARG A  90
SER A 126
SER A 127
 None
SO4  A 201 (-4.1A)
SO4  A 201 (-3.8A)
SO4  A 201 (-4.7A)
SO4  A 201 (-2.9A)
 0.65A 6jogA-4r0nA:
24.4		 6jogA-4r0nA:
41.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3w 2-AMINOMUCONATE
6-SEMIALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 GLY A 218
HIS A  17
ARG A  16
SER A  26
 None
 1.02A 6jogA-4u3wA:
3.4		 6jogA-4u3wA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ug4 CHOLINE SULFATASE

(Sinorhizobium
meliloti) 		PF00884
(Sulfatase)
PF12411
(Choline_sulf_C) 		4 GLY A 107
HIS A 112
SER A  82
SER A  81
 None
 1.04A 6jogA-4ug4A:
undetectable		 6jogA-4ug4A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x0e PROBABLE
NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		5 GLY A  11
THR A  12
HIS A  20
SER A 167
SER A 168
 None
 0.71A 6jogA-4x0eA:
14.9		 6jogA-4x0eA:
27.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ybr NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacterium
tuberculosis) 		PF01467
(CTP_transf_like) 		5 GLY A  11
THR A  12
HIS A  20
SER A 167
SER A 168
 NAP  A 301 (-3.4A)
NAP  A 301 (-3.7A)
NAP  A 301 (-3.8A)
None
NAP  A 301 (-2.4A)
 0.94A 6jogA-4ybrA:
15.0		 6jogA-4ybrA:
27.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5db4 NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF01467
(CTP_transf_like) 		5 GLY A  13
THR A  14
HIS A  22
SER A 168
SER A 169
 ATP  A 301 (-3.6A)
ATP  A 301 (-4.4A)
ATP  A 301 (-4.0A)
ATP  A 301 (-4.2A)
ATP  A 301 (-3.1A)
 0.50A 6jogA-5db4A:
16.0		 6jogA-5db4A:
27.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej3 ENDO-1,4-BETA-XYLANA
SE B

(Streptomyces
lividans) 		PF00457
(Glyco_hydro_11) 		4 GLY A  95
THR A  96
SER A 182
SER A 181
 None
 0.87A 6jogA-5ej3A:
undetectable		 6jogA-5ej3A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF

(Corynebacterium
ammoniagenes) 		PF01687
(Flavokinase)
PF06574
(FAD_syn) 		4 GLY A  22
HIS A  31
SER A 163
SER A 164
 PPV  A1339 ( 3.8A)
PPV  A1339 (-3.8A)
PPV  A1339 (-4.7A)
PPV  A1339 (-3.2A)
 0.53A 6jogA-5fo1A:
10.8		 6jogA-5fo1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gut DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH) 		4 GLY A1579
THR A1528
HIS A1575
SER A1551
 None
 1.07A 6jogA-5gutA:
3.0		 6jogA-5gutA:
11.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h16 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Acinetobacter
baumannii) 		PF01467
(CTP_transf_like) 		5 GLY A  10
THR A  11
HIS A  19
SER A 129
SER A 130
 CIT  A 201 (-3.2A)
CIT  A 201 (-3.6A)
CIT  A 201 (-3.8A)
CIT  A 201 (-3.5A)
CIT  A 201 (-2.6A)
 0.21A 6jogA-5h16A:
29.8		 6jogA-5h16A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ioo AVPA

(Nanoarchaeota
archaeon JGI
OTU-1) 		no annotation 4 GLY A 129
HIS A 171
SER A 125
SER A 126
 None
 1.04A 6jogA-5iooA:
undetectable		 6jogA-5iooA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5llt NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Plasmodium
falciparum) 		PF01467
(CTP_transf_like) 		4 GLY A  11
HIS A  20
SER A 167
SER A 168
 DND  A 301 (-3.6A)
DND  A 301 (-4.2A)
None
DND  A 301 ( 4.6A)
 0.17A 6jogA-5lltA:
16.1		 6jogA-5lltA:
23.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5o0d PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF01467
(CTP_transf_like) 		5 GLY A   8
HIS A  17
ARG A  90
SER A 126
SER A 127
 None
 0.45A 6jogA-5o0dA:
25.6		 6jogA-5o0dA:
39.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oc1 ARYL-ALCOHOL OXIDASE

(Pleurotus
eryngii) 		no annotation 4 GLY A 549
HIS A  91
SER A 207
SER A 200
 None
FAD  A 602 (-4.3A)
None
None
 1.10A 6jogA-5oc1A:
2.5		 6jogA-5oc1A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vkq NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L

(Drosophila
melanogaster) 		PF00023
(Ank)
PF00520
(Ion_trans)
PF12796
(Ank_2)
PF13637
(Ank_4) 		4 GLY A1077
THR A1073
HIS A1082
SER A1102
 None
 1.10A 6jogA-5vkqA:
undetectable		 6jogA-5vkqA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 GLY B 269
THR B 366
SER B 230
SER B 231
 None
 1.10A 6jogA-5w3jB:
undetectable		 6jogA-5w3jB:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xya -

(-) 		no annotation 4 GLY A 615
THR A 616
HIS A 279
SER A 346
 AES  A1701 (-3.5A)
AES  A1701 ( 4.7A)
AES  A1701 (-3.4A)
AES  A1701 ( 4.7A)
 0.96A 6jogA-5xyaA:
undetectable		 6jogA-5xyaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eys -

(-) 		no annotation 4 HIS B 216
ARG B 213
SER B 421
SER B 422
 None
 1.08A 6jogA-6eysB:
undetectable		 6jogA-6eysB:
undetectable