SIMILAR PATTERNS OF AMINO ACIDS FOR 6HZP_A_FVTA501_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3q | PROTEIN (NUCLEARFACTOR KAPPA-B P52) (Homo sapiens) |
PF00554(RHD_DNA_bind)PF16179(RHD_dimer) | 4 | VAL A 96GLN A 45PRO A 216ILE A 217 | None | 0.92A | 6hzpA-1a3qA:undetectable | 6hzpA-1a3qA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ako | EXONUCLEASE III (Escherichiacoli) |
PF03372(Exo_endo_phos) | 4 | VAL A 54GLN A 33ASN A 107ILE A 92 | None | 0.88A | 6hzpA-1akoA:undetectable | 6hzpA-1akoA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b25 | PROTEIN(FORMALDEHYDEFERREDOXINOXIDOREDUCTASE) (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 4 | VAL A 344ASN A 316ASN A 417PRO A 254 | None | 1.05A | 6hzpA-1b25A:undetectable | 6hzpA-1b25A:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cle | CHOLESTEROL ESTERASE ([Candida]cylindracea) |
PF00135(COesterase) | 4 | TYR A 156GLN A 62PRO A 130ILE A 132 | NoneNoneNoneCLL A 801 (-4.1A) | 1.11A | 6hzpA-1cleA:undetectable | 6hzpA-1cleA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ihp | PHYTASE (Aspergillusficuum) |
PF00328(His_Phos_2) | 4 | TYR A 272GLN A 368ASN A 365ILE A 366 | None | 1.06A | 6hzpA-1ihpA:1.1 | 6hzpA-1ihpA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1w | ISOCITRATEDEHYDROGENASE (Azotobactervinelandii) |
PF03971(IDH) | 4 | VAL A 293ASN A 294PRO A 264ILE A 265 | None | 1.09A | 6hzpA-1j1wA:0.6 | 6hzpA-1j1wA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jye | LACTOSE OPERONREPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 4 | ASN A 125GLN A 291PRO A 76ILE A 79 | NoneGOL A 350 (-3.4A)NoneNone | 0.85A | 6hzpA-1jyeA:undetectable | 6hzpA-1jyeA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m22 | PEPTIDE AMIDASE (Stenotrophomonasmaltophilia) |
PF01425(Amidase) | 4 | VAL A 208ASN A 234PRO A 230ILE A 233 | None | 0.74A | 6hzpA-1m22A:undetectable | 6hzpA-1m22A:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m7s | CATALASE (Pseudomonassyringae) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 139VAL A 375ASN A 376ASN A 338 | None | 1.11A | 6hzpA-1m7sA:undetectable | 6hzpA-1m7sA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sde | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Streptomycessp. R61) |
PF00144(Beta-lactamase) | 4 | VAL A 87ASN A 88GLN A 138PRO A 92 | None | 1.08A | 6hzpA-1sdeA:undetectable | 6hzpA-1sdeA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlf | LAC REPRESSOR (Escherichiacoli) |
PF13377(Peripla_BP_3) | 4 | ASN A 125GLN A 291PRO A 76ILE A 79 | IPT A 998 ( 4.7A)IPT A 998 ( 4.7A)IPT A 998 (-3.8A)None | 0.95A | 6hzpA-1tlfA:undetectable | 6hzpA-1tlfA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tmh | TRIOSEPHOSPHATEISOMERASE (Escherichiacoli) |
PF00121(TIM) | 4 | VAL A 117GLN A 91PRO A 125ILE A 93 | None | 1.06A | 6hzpA-1tmhA:undetectable | 6hzpA-1tmhA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ttu | LIN-12 AND GLP-1TRANSCRIPTIONALREGULATOR (Caenorhabditiselegans) |
PF01833(TIG)PF09270(BTD)PF09271(LAG1-DNAbind) | 4 | GLN A 554PRO A 558ILE A 559GLU A 550 | None | 0.93A | 6hzpA-1ttuA:undetectable | 6hzpA-1ttuA:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ue8 | 367AA LONGHYPOTHETICALCYTOCHROME P450 (Sulfurisphaeratokodaii) |
PF00067(p450) | 4 | VAL A 353ASN A 217ILE A 349GLU A 213 | None | 0.99A | 6hzpA-1ue8A:undetectable | 6hzpA-1ue8A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yi7 | BETA-XYLOSIDASE,FAMILY 43 GLYCOSYLHYDROLASE (Clostridiumacetobutylicum) |
PF04616(Glyco_hydro_43) | 4 | GLN A 293ASN A 6PRO A 7ILE A 8 | None | 1.00A | 6hzpA-1yi7A:undetectable | 6hzpA-1yi7A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yrz | XYLANBETA-1,4-XYLOSIDASE (Bacillushalodurans) |
PF04616(Glyco_hydro_43) | 4 | GLN A1285ASN A1007PRO A1008ILE A1009 | None | 1.06A | 6hzpA-1yrzA:undetectable | 6hzpA-1yrzA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z2o | INOSITOL1,3,4-TRISPHOSPHATE5/6-KINASE (Entamoebahistolytica) |
PF05770(Ins134_P3_kin) | 4 | VAL X 263GLN X 168ASN X 98ILE X 97 | NoneADP X 871 (-3.8A)NoneNone | 0.98A | 6hzpA-1z2oX:undetectable | 6hzpA-1z2oX:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amc | PHENYLALANYL-TRNASYNTHETASE BETACHAIN (Thermusthermophilus) |
PF01409(tRNA-synt_2d)PF01588(tRNA_bind)PF03147(FDX-ACB)PF03483(B3_4)PF03484(B5) | 4 | VAL B 223ASN B 243ILE B 242GLU B 323 | None | 1.06A | 6hzpA-2amcB:undetectable | 6hzpA-2amcB:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cvt | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASELARGE CHAIN 1 (Saccharomycescerevisiae) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 4 | VAL A 484ASN A 488ASN A 207PRO A 213 | None | 1.12A | 6hzpA-2cvtA:2.1 | 6hzpA-2cvtA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0v | METHANOLDEHYDROGENASE LARGESUBUNIT (Hyphomicrobiumdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | VAL A 528GLN A 39ASN A 36ILE A 32 | None | 1.09A | 6hzpA-2d0vA:undetectable | 6hzpA-2d0vA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dnw | ACYL CARRIER PROTEIN (Homo sapiens) |
PF00550(PP-binding) | 4 | VAL A 23GLN A 52PRO A 78ILE A 81 | None | 1.07A | 6hzpA-2dnwA:undetectable | 6hzpA-2dnwA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2egu | CYSTEINE SYNTHASE (Geobacilluskaustophilus) |
PF00291(PALP) | 4 | VAL A 44ASN A 39GLN A 165GLU A 161 | None | 1.11A | 6hzpA-2eguA:undetectable | 6hzpA-2eguA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ep5 | 350AA LONGHYPOTHETICALASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Sulfurisphaeratokodaii) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | ASN A 121GLN A 273PRO A 122ILE A 124 | None | 1.12A | 6hzpA-2ep5A:undetectable | 6hzpA-2ep5A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exh | BETA-D-XYLOSIDASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43) | 4 | GLN A 293ASN A 6PRO A 7ILE A 8 | None | 0.97A | 6hzpA-2exhA:undetectable | 6hzpA-2exhA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fav | REPLICASEPOLYPROTEIN 1AB(PP1AB) (ORF1AB) (Severe acuterespiratorysyndrome-relatedcoronavirus) |
PF01661(Macro) | 4 | VAL A 4ASN A 5GLN A 120ILE A 122 | None | 0.96A | 6hzpA-2favA:undetectable | 6hzpA-2favA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gj4 | GLYCOGENPHOSPHORYLASE,MUSCLE FORM (Oryctolaguscuniculus) |
PF00343(Phosphorylase) | 4 | VAL A 629GLN A 740ASN A 588ILE A 584 | None | 1.01A | 6hzpA-2gj4A:undetectable | 6hzpA-2gj4A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2his | CELLULOMONAS FIMIFAMILY 10BETA-1,4-GLYCANASE (Cellulomonasfimi) |
PF00331(Glyco_hydro_10) | 4 | VAL A 285GLN A 203ASN A 205GLU A 233 | NoneGLC A 602 (-3.1A)GLC A 602 (-3.8A)GLC A 602 ( 1.9A) | 1.05A | 6hzpA-2hisA:undetectable | 6hzpA-2hisA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpv | FMN-DEPENDENTNADH-AZOREDUCTASE (Enterococcusfaecalis) |
PF02525(Flavodoxin_2) | 4 | VAL A 117GLN A 147ASN A 102ILE A 100 | None | 0.90A | 6hzpA-2hpvA:undetectable | 6hzpA-2hpvA:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1w | ENDOPLASMIN (Canis lupus) |
PF00183(HSP90)PF02518(HATPase_c) | 4 | TYR A 412VAL A 436PRO A 341ILE A 342 | None | 1.12A | 6hzpA-2o1wA:undetectable | 6hzpA-2o1wA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qc5 | STREPTOGRAMIN BLACTONASE (Staphylococcuscohnii) |
no annotation | 4 | ASN A 204GLN A 247ILE A 220GLU A 259 | ASN A 204 ( 0.6A)GLN A 247 ( 0.6A)ILE A 220 ( 0.7A)GLU A 259 ( 0.6A) | 1.08A | 6hzpA-2qc5A:undetectable | 6hzpA-2qc5A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r9v | ATP SYNTHASE SUBUNITALPHA (Thermotogamaritima) |
PF00006(ATP-synt_ab)PF00306(ATP-synt_ab_C)PF02874(ATP-synt_ab_N) | 4 | GLN A 164PRO A 159ILE A 158GLU A 166 | None | 0.94A | 6hzpA-2r9vA:undetectable | 6hzpA-2r9vA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2voa | EXODEOXYRIBONUCLEASEIII (Archaeoglobusfulgidus) |
PF03372(Exo_endo_phos) | 4 | VAL A 55GLN A 34ASN A 103ILE A 92 | None | 0.80A | 6hzpA-2voaA:undetectable | 6hzpA-2voaA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkk | TOPOISOMERASE IV (Acinetobacterbaumannii) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 4 | TYR A1028GLN A1148PRO A1044GLU A1157 | None | 1.02A | 6hzpA-2xkkA:2.1 | 6hzpA-2xkkA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsg | CCMAN5 (Cellulosimicrobiumcellulans) |
PF07971(Glyco_hydro_92) | 4 | VAL A 721GLN A 688ASN A 599PRO A 604 | None | 0.93A | 6hzpA-2xsgA:undetectable | 6hzpA-2xsgA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2n | VIRGINIAMYCIN BLYASE (Staphylococcusaureus) |
no annotation | 4 | ASN A 78ASN A 96PRO A 97GLU A 133 | None | 1.06A | 6hzpA-2z2nA:undetectable | 6hzpA-2z2nA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 4 | VAL A 781GLN A 566ILE A 689GLU A 664 | None | 0.95A | 6hzpA-3cemA:undetectable | 6hzpA-3cemA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dan | CYTOCHROME P450 74A2 (Partheniumargentatum) |
PF00067(p450) | 4 | TYR A 335VAL A 433ILE A 324GLU A 325 | None | 0.98A | 6hzpA-3danA:undetectable | 6hzpA-3danA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e5y | TRMH FAMILY RNAMETHYLTRANSFERASE (Burkholderiapseudomallei) |
PF00588(SpoU_methylase) | 4 | ASN A 14PRO A 13ILE A 11GLU A 104 | None | 1.04A | 6hzpA-3e5yA:undetectable | 6hzpA-3e5yA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1w | MANNOSE-6-PHOSPHATEISOMERASE (Salmonellaenterica) |
PF01238(PMI_typeI) | 4 | VAL A 8ASN A 10GLN A 30PRO A 32 | None | 1.09A | 6hzpA-3h1wA:undetectable | 6hzpA-3h1wA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h84 | ATPASE GET3 (Saccharomycescerevisiae) |
PF02374(ArsA_ATPase) | 4 | ASN A 339ASN A 279PRO A 340ILE A 341 | None | 1.08A | 6hzpA-3h84A:undetectable | 6hzpA-3h84A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvy | CYSTATHIONINEBETA-LYASE FAMILYPROTEIN, YNBBB.SUBTILIS ORTHOLOG (Clostridiumacetobutylicum) |
PF06838(Met_gamma_lyase) | 4 | TYR A 187VAL A 375GLN A 405ILE A 348 | None | 1.01A | 6hzpA-3hvyA:undetectable | 6hzpA-3hvyA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzr | TRYPTOPHANYL-TRNASYNTHETASE (Entamoebahistolytica) |
PF00579(tRNA-synt_1b) | 4 | VAL A 172GLN A 83PRO A 199ILE A 201 | None | 1.06A | 6hzpA-3hzrA:undetectable | 6hzpA-3hzrA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ivu | HOMOCITRATESYNTHASE,MITOCHONDRIAL (Schizosaccharomycespombe) |
PF00682(HMGL-like) | 5 | VAL A 300ASN A 306PRO A 303ILE A 302GLU A 291 | None | 1.16A | 6hzpA-3ivuA:undetectable | 6hzpA-3ivuA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2j | PROTEIN VP1PROTEIN VP3 (Enterovirus B;Enterovirus B) |
PF00073(Rhv)PF00073(Rhv) | 4 | VAL B 94GLN B 81ASN A 217ILE A 216 | None | 0.86A | 6hzpA-3j2jB:undetectable | 6hzpA-3j2jB:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1i | FLAGELLAR PROTEIN (Helicobacterpylori) |
PF02561(FliS) | 4 | VAL A 96ASN A 95ASN A 55ILE A 51 | None | 1.08A | 6hzpA-3k1iA:4.4 | 6hzpA-3k1iA:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1u | BETA-XYLOSIDASE,FAMILY 43 GLYCOSYLHYDROLASE (Clostridiumacetobutylicum) |
PF04616(Glyco_hydro_43) | 4 | GLN A 299ASN A 8PRO A 9ILE A 10 | None | 0.81A | 6hzpA-3k1uA:undetectable | 6hzpA-3k1uA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 4 | TYR A 515VAL A 517ASN A 564GLN A 593 | None | 0.85A | 6hzpA-3lk6A:2.1 | 6hzpA-3lk6A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lv4 | GLYCOSIDE HYDROLASEYXIA (Bacilluslicheniformis) |
PF04616(Glyco_hydro_43)PF16369(GH43_C) | 4 | ASN A 86PRO A 85ILE A 84GLU A 90 | None | 0.90A | 6hzpA-3lv4A:undetectable | 6hzpA-3lv4A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nk7 | 23S RRNAMETHYLTRANSFERASE (Streptomycesactuosus) |
PF00588(SpoU_methylase)PF04705(TSNR_N) | 4 | VAL A 81ASN A 9ILE A 7GLU A 3 | None | 1.07A | 6hzpA-3nk7A:undetectable | 6hzpA-3nk7A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3noj | 4-CARBOXY-4-HYDROXY-2-OXOADIPATEALDOLASE/OXALOACETATE DECARBOXYLASE (Pseudomonasputida) |
PF03737(RraA-like) | 4 | VAL A 153ASN A 154PRO A 166ILE A 15 | None | 1.04A | 6hzpA-3nojA:undetectable | 6hzpA-3nojA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nx6 | 10KDA CHAPERONIN (Xanthomonasoryzae) |
PF00166(Cpn10) | 4 | TYR A 82VAL A 41PRO A 14ILE A 15 | None | 0.96A | 6hzpA-3nx6A:undetectable | 6hzpA-3nx6A:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o9p | PERIPLASMIC MUREINPEPTIDE-BINDINGPROTEIN (Escherichiacoli) |
PF00496(SBP_bac_5) | 4 | TYR A 506VAL A 504ASN A 500ASN A 51 | None | 0.92A | 6hzpA-3o9pA:undetectable | 6hzpA-3o9pA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opw | DNADAMAGE-RESPONSIVETRANSCRIPTIONALREPRESSOR RPH1 (Saccharomycescerevisiae) |
PF02373(JmjC)PF02375(JmjN) | 4 | VAL A 43GLN A 298PRO A 259ILE A 258 | None | 1.11A | 6hzpA-3opwA:undetectable | 6hzpA-3opwA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qiv | SHORT-CHAINDEHYDROGENASE OR3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | VAL A 159ASN A 162ASN A 240ILE A 238 | None | 1.08A | 6hzpA-3qivA:undetectable | 6hzpA-3qivA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr1 | PHOSPHOLIPASE C-BETA(PLC-BETA) (Doryteuthispealeii) |
PF00168(C2)PF00387(PI-PLC-Y)PF00388(PI-PLC-X)PF09279(EF-hand_like) | 4 | VAL A 605ASN A 724ILE A 722GLU A 672 | None | 0.96A | 6hzpA-3qr1A:undetectable | 6hzpA-3qr1A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tfj | GCVT-LIKEAMINOMETHYLTRANSFERASE PROTEIN (CandidatusPelagibacterubique) |
PF01571(GCV_T)PF08669(GCV_T_C) | 4 | VAL A 106ASN A 107ASN A 33ILE A 123 | None | 1.08A | 6hzpA-3tfjA:undetectable | 6hzpA-3tfjA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ugv | ENOLASE (alphaproteobacteriumBAL199) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | TYR A 55GLN A 205ASN A 255GLU A 229 | None | 1.09A | 6hzpA-3ugvA:undetectable | 6hzpA-3ugvA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujh | GLUCOSE-6-PHOSPHATEISOMERASE (Toxoplasmagondii) |
PF00342(PGI) | 4 | TYR A 293GLN A 417PRO A 484ILE A 487 | None | 0.79A | 6hzpA-3ujhA:undetectable | 6hzpA-3ujhA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ukf | UDP-GALACTOPYRANOSEMUTASE (Aspergillusfumigatus) |
PF13450(NAD_binding_8) | 4 | TYR A 69VAL A 487ASN A 488ASN A 457 | NoneNoneNoneGDU A 802 ( 4.0A) | 1.07A | 6hzpA-3ukfA:undetectable | 6hzpA-3ukfA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsc | PROTEIN CYSO (Aeropyrumpernix) |
PF00291(PALP) | 4 | VAL A 126ASN A 120GLN A 245GLU A 241 | None | 1.05A | 6hzpA-3vscA:undetectable | 6hzpA-3vscA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a7k | ALDOS-2-ULOSEDEHYDRATASE (Phanerochaetechrysosporium) |
no annotation | 4 | TYR A 284VAL A 277PRO A 221ILE A 219 | None | 1.09A | 6hzpA-4a7kA:undetectable | 6hzpA-4a7kA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b7g | CATALASE (Corynebacteriumglutamicum) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 132VAL A 370ASN A 371ASN A 333 | None | 1.11A | 6hzpA-4b7gA:undetectable | 6hzpA-4b7gA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dwq | TRNA-SPLICING LIGASERTCB (Pyrococcushorikoshii) |
PF01139(RtcB) | 4 | TYR A 248VAL A 244PRO A 89ILE A 92 | PO4 A 507 ( 4.8A)NoneNoneNone | 0.95A | 6hzpA-4dwqA:undetectable | 6hzpA-4dwqA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fk7 | PUTATIVEADP-RIBOSYLTRANSFERASE CERTHRAX (Bacillus cereus) |
PF03496(ADPrib_exo_Tox) | 4 | TYR A 442VAL A 463GLN A 382ILE A 409 | None | 1.07A | 6hzpA-4fk7A:undetectable | 6hzpA-4fk7A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fxd | DNA POLYMERASE ALPHACATALYTIC SUBUNIT A (Saccharomycescerevisiae) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | TYR A 799VAL A 486ASN A 480GLU A 361 | None | 1.11A | 6hzpA-4fxdA:undetectable | 6hzpA-4fxdA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h3s | GLUTAMINE-TRNALIGASE (Saccharomycescerevisiae) |
PF00749(tRNA-synt_1c)PF03950(tRNA-synt_1c_C)PF04557(tRNA_synt_1c_R2) | 4 | TYR A 706VAL A 733ILE A 796GLU A 789 | None | 1.06A | 6hzpA-4h3sA:undetectable | 6hzpA-4h3sA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hb4 | EXPORTIN-1 (Saccharomycescerevisiae) |
PF03810(IBN_N)PF08389(Xpo1)PF08767(CRM1_C) | 4 | TYR C 645GLN C 720ASN C 706ILE C 702 | None | 1.07A | 6hzpA-4hb4C:1.9 | 6hzpA-4hb4C:19.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ikv | DI-TRIPEPTIDE ABCTRANSPORTER(PERMEASE) (Geobacilluskaustophilus) |
PF00854(PTR2) | 7 | TYR A 40ASN A 166GLN A 309ASN A 342PRO A 343ILE A 346GLU A 413 | None | 0.37A | 6hzpA-4ikvA:52.8 | 6hzpA-4ikvA:49.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kqx | KETOL-ACIDREDUCTOISOMERASE (Slackia exigua) |
PF01450(IlvC)PF07991(IlvN) | 4 | VAL A 246ASN A 258ILE A 254GLU A 269 | None | 1.08A | 6hzpA-4kqxA:undetectable | 6hzpA-4kqxA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l27 | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
no annotation | 4 | VAL B 118ASN B 113GLN B 243GLU B 239 | None | 1.10A | 6hzpA-4l27B:undetectable | 6hzpA-4l27B:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mfi | SN-GLYCEROL-3-PHOSPHATE ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN USPB (Mycobacteriumtuberculosis) |
PF13416(SBP_bac_8) | 4 | TYR A 131VAL A 348ASN A 332PRO A 333 | None | 1.07A | 6hzpA-4mfiA:undetectable | 6hzpA-4mfiA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n5a | PROTEIN EFR3 (Saccharomycescerevisiae) |
no annotation | 4 | ASN A 314PRO A 315ILE A 316GLU A 356 | None | 1.12A | 6hzpA-4n5aA:undetectable | 6hzpA-4n5aA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n5c | CARGO-TRANSPORTPROTEIN YPP1 (Saccharomycescerevisiae) |
no annotation | 4 | ASN A 347GLN A 274ILE A 306GLU A 307 | None | 1.07A | 6hzpA-4n5cA:undetectable | 6hzpA-4n5cA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rv2 | MAOC FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF01575(MaoC_dehydratas) | 4 | ASN B 38GLN B 49PRO B 39ILE B 40 | None | 0.93A | 6hzpA-4rv2B:undetectable | 6hzpA-4rv2B:17.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4tpg | PROTON:OLIGOPEPTIDESYMPORTER POT FAMILY (Shewanellaoneidensis) |
PF00854(PTR2) | 7 | TYR A 29VAL A 150ASN A 151ASN A 329PRO A 330ILE A 333GLU A 402 | None | 0.61A | 6hzpA-4tpgA:38.9 | 6hzpA-4tpgA:30.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4w6v | DI-/TRIPEPTIDETRANSPORTER (Yersiniaenterocolitica) |
PF00854(PTR2) | 5 | TYR A 35ASN A 163ASN A 344ILE A 348GLU A 420 | None | 0.72A | 6hzpA-4w6vA:44.3 | 6hzpA-4w6vA:34.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxj | GLUTAMATE RECEPTORIIB,GLUTAMATERECEPTOR IIB (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 4 | TYR A 68ASN A 66ASN A 180GLU A 182 | GLU A 301 (-2.8A)NoneNoneNone | 1.11A | 6hzpA-4wxjA:undetectable | 6hzpA-4wxjA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgt | FRQ-INTERACTING RNAHELICASE (Neurosporacrassa) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 4 | GLN A 647ASN A 329PRO A 328ILE A 327 | None | 1.07A | 6hzpA-4xgtA:2.0 | 6hzpA-4xgtA:19.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xni | DI-OR TRIPEPTIDE:H+SYMPORTER (Streptococcusthermophilus) |
PF00854(PTR2) | 6 | TYR A 30ASN A 156ASN A 328PRO A 329ILE A 332GLU A 400 | None | 0.79A | 6hzpA-4xniA:46.5 | 6hzpA-4xniA:42.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xni | DI-OR TRIPEPTIDE:H+SYMPORTER (Streptococcusthermophilus) |
PF00854(PTR2) | 4 | VAL A 152ASN A 156ILE A 332GLU A 400 | None | 0.96A | 6hzpA-4xniA:46.5 | 6hzpA-4xniA:42.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xz3 | ACYL-COA SYNTHETASE(NDP FORMING) (CandidatusKorarchaeumcryptofilum) |
PF13380(CoA_binding_2)PF13607(Succ_CoA_lig) | 4 | VAL A 379ASN A 348PRO A 349ILE A 350 | None | 1.10A | 6hzpA-4xz3A:undetectable | 6hzpA-4xz3A:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zkt | BOTULINUM NEUROTOXINTYPE E,NONTOXIC-NONHEMAGGLUTININ COMPONENT,NTNH (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07953(Toxin_R_bind_N)PF08470(NTNH_C) | 4 | ASN B 892ASN B 907ILE B 909GLU B 915 | None | 0.84A | 6hzpA-4zktB:2.4 | 6hzpA-4zktB:18.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d3m | ENERGY-COUPLINGFACTOR TRANSPORTERTRANSMEMBRANEPROTEIN ECFT (Lactobacillusdelbrueckii) |
PF02361(CbiQ) | 4 | TYR D 44ASN D 40GLN D 83ASN D 108 | None | 1.00A | 6hzpA-5d3mD:undetectable | 6hzpA-5d3mD:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g06 | EXOSOME COMPLEXCOMPONENT SKI6 (Saccharomycescerevisiae) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | VAL B 189GLN B 44ASN B 141ILE B 140 | None | 1.09A | 6hzpA-5g06B:undetectable | 6hzpA-5g06B:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hmp | UNCONVENTIONALMYOSIN-VC (Homo sapiens) |
PF00063(Myosin_head) | 4 | VAL A 341GLN A 371ASN A 375PRO A 388 | None | 1.03A | 6hzpA-5hmpA:1.8 | 6hzpA-5hmpA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huc | 3-DEOXY-D-ARABINO-HEPTULOSONATE7-PHOSPHATE (DAHP)SYNTHASE (Corynebacteriumglutamicum) |
PF01474(DAHP_synth_2) | 4 | GLN A 457ASN A 455ILE A 437GLU A 435 | None | 0.93A | 6hzpA-5hucA:undetectable | 6hzpA-5hucA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iuy | MULTIDRUG EFFLUXOUTER MEMBRANEPROTEIN OPRN (Pseudomonasaeruginosa) |
PF02321(OEP) | 4 | GLN A 414ASN A 173ILE A 169GLU A 418 | None | 0.65A | 6hzpA-5iuyA:4.0 | 6hzpA-5iuyA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxl | FLAGELLAR HOOKPROTEIN FLGE (Campylobacterjejuni) |
PF00460(Flg_bb_rod)PF06429(Flg_bbr_C)PF07196(Flagellin_IN)PF07559(FlaE) | 4 | VAL A 522ASN A 536ASN A 538ILE A 594 | None | 1.08A | 6hzpA-5jxlA:2.6 | 6hzpA-5jxlA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kvu | ISOCITRATEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF03971(IDH) | 4 | VAL A 295ASN A 296PRO A 266ILE A 267 | None | 1.04A | 6hzpA-5kvuA:undetectable | 6hzpA-5kvuA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5maw | FLAGELLAR PROTEINFLIS (Bacillussubtilis) |
no annotation | 4 | TYR E 86VAL E 90ASN E 59ILE E 55 | None | 0.80A | 6hzpA-5mawE:4.3 | 6hzpA-5mawE:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sy5 | NEURONAL PASDOMAIN-CONTAININGPROTEIN 1 (Mus musculus) |
PF00010(HLH)PF00989(PAS)PF08447(PAS_3) | 4 | VAL B 92GLN B 155ASN B 154GLU B 156 | None | 0.77A | 6hzpA-5sy5B:undetectable | 6hzpA-5sy5B:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tuk | TETRACYCLINEDESTRUCTASE TET(51) (unculturedbacterium) |
PF01494(FAD_binding_3) | 4 | VAL A 348GLN A 304ASN A 341ILE A 374 | None | 1.12A | 6hzpA-5tukA:undetectable | 6hzpA-5tukA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5una | 7SK SNRNAMETHYLPHOSPHATECAPPING ENZYME (Homo sapiens) |
PF06859(Bin3)PF13847(Methyltransf_31) | 4 | VAL A 561ASN A 559GLN A 414ILE A 475 | SAH A 701 (-4.7A)SAH A 701 (-3.6A)NoneSAH A 701 (-3.8A) | 1.09A | 6hzpA-5unaA:undetectable | 6hzpA-5unaA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wlh | LBACAS13A H328A(C2C2) (LachnospiraceaebacteriumNK4A179) |
no annotation | 4 | VAL A 680ASN A 683GLN A1087ILE A1080 | IOD A1510 ( 4.4A) U B 12 ( 3.1A)NoneNone | 1.02A | 6hzpA-5wlhA:undetectable | 6hzpA-5wlhA:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x5y | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF03739(YjgP_YjgQ) | 4 | VAL F 254GLN F 61PRO F 122ILE F 125 | None | 0.78A | 6hzpA-5x5yF:2.7 | 6hzpA-5x5yF:23.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xsx | CHITINASE (Thermococcuschitonophagus) |
no annotation | 4 | ASN A 699PRO A 695ILE A 698GLU A 649 | None | 1.05A | 6hzpA-5xsxA:undetectable | 6hzpA-5xsxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bsu | XYLOGLUCAN6-XYLOSYLTRANSFERASE1 (Arabidopsisthaliana) |
no annotation | 4 | TYR A 170VAL A 166ASN A 164PRO A 383 | None | 1.02A | 6hzpA-6bsuA:undetectable | 6hzpA-6bsuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ei3 | PROTON-DEPENDENTOLIGOPEPTIDETRANSPORTER FAMILYPROTEIN (Xanthomonascampestris) |
no annotation | 5 | TYR A 34ASN A 164ASN A 350PRO A 351GLU A 425 | None | 0.43A | 6hzpA-6ei3A:38.7 | 6hzpA-6ei3A:26.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6en3 | ENDO-BETA-N-ACETYLGLUCOSAMINIDASEF2,MULTIFUNCTIONAL-AUTOPROCESSINGREPEATS-IN-TOXIN (Vibriocholerae;Streptococcuspyogenes) |
no annotation | 4 | TYR A 709VAL A 707ASN A 677ILE A 676 | None | 0.98A | 6hzpA-6en3A:undetectable | 6hzpA-6en3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6exs | PEPTIDE ABCTRANSPORTER PERMEASE (Staphylococcushominis) |
no annotation | 8 | TYR A 41VAL A 166ASN A 167GLN A 310ASN A 347PRO A 348ILE A 351GLU A 418 | C3H A 514 (-4.0A)NoneC3H A 514 (-3.6A)C3H A 514 (-3.5A)C3H A 514 (-4.0A)C3H A 514 (-4.1A)NoneNone | 0.24A | 6hzpA-6exsA:62.6 | 6hzpA-6exsA:undetectable |