SIMILAR PATTERNS OF AMINO ACIDS FOR 6HZP_A_FVTA501

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3q PROTEIN (NUCLEAR
FACTOR KAPPA-B P52)


(Homo sapiens)
PF00554
(RHD_DNA_bind)
PF16179
(RHD_dimer)
4 VAL A  96
GLN A  45
PRO A 216
ILE A 217
None
0.92A 6hzpA-1a3qA:
undetectable
6hzpA-1a3qA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ako EXONUCLEASE III

(Escherichia
coli)
PF03372
(Exo_endo_phos)
4 VAL A  54
GLN A  33
ASN A 107
ILE A  92
None
0.88A 6hzpA-1akoA:
undetectable
6hzpA-1akoA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)


(Pyrococcus
furiosus)
PF01314
(AFOR_C)
PF02730
(AFOR_N)
4 VAL A 344
ASN A 316
ASN A 417
PRO A 254
None
1.05A 6hzpA-1b25A:
undetectable
6hzpA-1b25A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cle CHOLESTEROL ESTERASE

([Candida]
cylindracea)
PF00135
(COesterase)
4 TYR A 156
GLN A  62
PRO A 130
ILE A 132
None
None
None
CLL  A 801 (-4.1A)
1.11A 6hzpA-1cleA:
undetectable
6hzpA-1cleA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ihp PHYTASE

(Aspergillus
ficuum)
PF00328
(His_Phos_2)
4 TYR A 272
GLN A 368
ASN A 365
ILE A 366
None
1.06A 6hzpA-1ihpA:
1.1
6hzpA-1ihpA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE


(Azotobacter
vinelandii)
PF03971
(IDH)
4 VAL A 293
ASN A 294
PRO A 264
ILE A 265
None
1.09A 6hzpA-1j1wA:
0.6
6hzpA-1j1wA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jye LACTOSE OPERON
REPRESSOR


(Escherichia
coli)
PF13377
(Peripla_BP_3)
4 ASN A 125
GLN A 291
PRO A  76
ILE A  79
None
GOL  A 350 (-3.4A)
None
None
0.85A 6hzpA-1jyeA:
undetectable
6hzpA-1jyeA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m22 PEPTIDE AMIDASE

(Stenotrophomonas
maltophilia)
PF01425
(Amidase)
4 VAL A 208
ASN A 234
PRO A 230
ILE A 233
None
0.74A 6hzpA-1m22A:
undetectable
6hzpA-1m22A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m7s CATALASE

(Pseudomonas
syringae)
PF00199
(Catalase)
PF06628
(Catalase-rel)
4 TYR A 139
VAL A 375
ASN A 376
ASN A 338
None
1.11A 6hzpA-1m7sA:
undetectable
6hzpA-1m7sA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sde D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE


(Streptomyces
sp. R61)
PF00144
(Beta-lactamase)
4 VAL A  87
ASN A  88
GLN A 138
PRO A  92
None
1.08A 6hzpA-1sdeA:
undetectable
6hzpA-1sdeA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlf LAC REPRESSOR

(Escherichia
coli)
PF13377
(Peripla_BP_3)
4 ASN A 125
GLN A 291
PRO A  76
ILE A  79
IPT  A 998 ( 4.7A)
IPT  A 998 ( 4.7A)
IPT  A 998 (-3.8A)
None
0.95A 6hzpA-1tlfA:
undetectable
6hzpA-1tlfA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmh TRIOSEPHOSPHATE
ISOMERASE


(Escherichia
coli)
PF00121
(TIM)
4 VAL A 117
GLN A  91
PRO A 125
ILE A  93
None
1.06A 6hzpA-1tmhA:
undetectable
6hzpA-1tmhA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ttu LIN-12 AND GLP-1
TRANSCRIPTIONAL
REGULATOR


(Caenorhabditis
elegans)
PF01833
(TIG)
PF09270
(BTD)
PF09271
(LAG1-DNAbind)
4 GLN A 554
PRO A 558
ILE A 559
GLU A 550
None
0.93A 6hzpA-1ttuA:
undetectable
6hzpA-1ttuA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ue8 367AA LONG
HYPOTHETICAL
CYTOCHROME P450


(Sulfurisphaera
tokodaii)
PF00067
(p450)
4 VAL A 353
ASN A 217
ILE A 349
GLU A 213
None
0.99A 6hzpA-1ue8A:
undetectable
6hzpA-1ue8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yi7 BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE


(Clostridium
acetobutylicum)
PF04616
(Glyco_hydro_43)
4 GLN A 293
ASN A   6
PRO A   7
ILE A   8
None
1.00A 6hzpA-1yi7A:
undetectable
6hzpA-1yi7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yrz XYLAN
BETA-1,4-XYLOSIDASE


(Bacillus
halodurans)
PF04616
(Glyco_hydro_43)
4 GLN A1285
ASN A1007
PRO A1008
ILE A1009
None
1.06A 6hzpA-1yrzA:
undetectable
6hzpA-1yrzA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z2o INOSITOL
1,3,4-TRISPHOSPHATE
5/6-KINASE


(Entamoeba
histolytica)
PF05770
(Ins134_P3_kin)
4 VAL X 263
GLN X 168
ASN X  98
ILE X  97
None
ADP  X 871 (-3.8A)
None
None
0.98A 6hzpA-1z2oX:
undetectable
6hzpA-1z2oX:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN


(Thermus
thermophilus)
PF01409
(tRNA-synt_2d)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5)
4 VAL B 223
ASN B 243
ILE B 242
GLU B 323
None
1.06A 6hzpA-2amcB:
undetectable
6hzpA-2amcB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1


(Saccharomyces
cerevisiae)
PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone)
4 VAL A 484
ASN A 488
ASN A 207
PRO A 213
None
1.12A 6hzpA-2cvtA:
2.1
6hzpA-2cvtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0v METHANOL
DEHYDROGENASE LARGE
SUBUNIT


(Hyphomicrobium
denitrificans)
PF01011
(PQQ)
PF13360
(PQQ_2)
4 VAL A 528
GLN A  39
ASN A  36
ILE A  32
None
1.09A 6hzpA-2d0vA:
undetectable
6hzpA-2d0vA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dnw ACYL CARRIER PROTEIN

(Homo sapiens)
PF00550
(PP-binding)
4 VAL A  23
GLN A  52
PRO A  78
ILE A  81
None
1.07A 6hzpA-2dnwA:
undetectable
6hzpA-2dnwA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egu CYSTEINE SYNTHASE

(Geobacillus
kaustophilus)
PF00291
(PALP)
4 VAL A  44
ASN A  39
GLN A 165
GLU A 161
None
1.11A 6hzpA-2eguA:
undetectable
6hzpA-2eguA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ep5 350AA LONG
HYPOTHETICAL
ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE


(Sulfurisphaera
tokodaii)
PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC)
4 ASN A 121
GLN A 273
PRO A 122
ILE A 124
None
1.12A 6hzpA-2ep5A:
undetectable
6hzpA-2ep5A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exh BETA-D-XYLOSIDASE

(Geobacillus
stearothermophilus)
PF04616
(Glyco_hydro_43)
4 GLN A 293
ASN A   6
PRO A   7
ILE A   8
None
0.97A 6hzpA-2exhA:
undetectable
6hzpA-2exhA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fav REPLICASE
POLYPROTEIN 1AB
(PP1AB) (ORF1AB)


(Severe acute
respiratory
syndrome-related
coronavirus)
PF01661
(Macro)
4 VAL A   4
ASN A   5
GLN A 120
ILE A 122
None
0.96A 6hzpA-2favA:
undetectable
6hzpA-2favA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM


(Oryctolagus
cuniculus)
PF00343
(Phosphorylase)
4 VAL A 629
GLN A 740
ASN A 588
ILE A 584
None
1.01A 6hzpA-2gj4A:
undetectable
6hzpA-2gj4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2his CELLULOMONAS FIMI
FAMILY 10
BETA-1,4-GLYCANASE


(Cellulomonas
fimi)
PF00331
(Glyco_hydro_10)
4 VAL A 285
GLN A 203
ASN A 205
GLU A 233
None
GLC  A 602 (-3.1A)
GLC  A 602 (-3.8A)
GLC  A 602 ( 1.9A)
1.05A 6hzpA-2hisA:
undetectable
6hzpA-2hisA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpv FMN-DEPENDENT
NADH-AZOREDUCTASE


(Enterococcus
faecalis)
PF02525
(Flavodoxin_2)
4 VAL A 117
GLN A 147
ASN A 102
ILE A 100
None
0.90A 6hzpA-2hpvA:
undetectable
6hzpA-2hpvA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1w ENDOPLASMIN

(Canis lupus)
PF00183
(HSP90)
PF02518
(HATPase_c)
4 TYR A 412
VAL A 436
PRO A 341
ILE A 342
None
1.12A 6hzpA-2o1wA:
undetectable
6hzpA-2o1wA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qc5 STREPTOGRAMIN B
LACTONASE


(Staphylococcus
cohnii)
no annotation 4 ASN A 204
GLN A 247
ILE A 220
GLU A 259
ASN  A 204 ( 0.6A)
GLN  A 247 ( 0.6A)
ILE  A 220 ( 0.7A)
GLU  A 259 ( 0.6A)
1.08A 6hzpA-2qc5A:
undetectable
6hzpA-2qc5A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9v ATP SYNTHASE SUBUNIT
ALPHA


(Thermotoga
maritima)
PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
4 GLN A 164
PRO A 159
ILE A 158
GLU A 166
None
0.94A 6hzpA-2r9vA:
undetectable
6hzpA-2r9vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2voa EXODEOXYRIBONUCLEASE
III


(Archaeoglobus
fulgidus)
PF03372
(Exo_endo_phos)
4 VAL A  55
GLN A  34
ASN A 103
ILE A  92
None
0.80A 6hzpA-2voaA:
undetectable
6hzpA-2voaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xkk TOPOISOMERASE IV

(Acinetobacter
baumannii)
PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim)
4 TYR A1028
GLN A1148
PRO A1044
GLU A1157
None
1.02A 6hzpA-2xkkA:
2.1
6hzpA-2xkkA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans)
PF07971
(Glyco_hydro_92)
4 VAL A 721
GLN A 688
ASN A 599
PRO A 604
None
0.93A 6hzpA-2xsgA:
undetectable
6hzpA-2xsgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z2n VIRGINIAMYCIN B
LYASE


(Staphylococcus
aureus)
no annotation 4 ASN A  78
ASN A  96
PRO A  97
GLU A 133
None
1.06A 6hzpA-2z2nA:
undetectable
6hzpA-2z2nA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM


(Homo sapiens)
PF00343
(Phosphorylase)
4 VAL A 781
GLN A 566
ILE A 689
GLU A 664
None
0.95A 6hzpA-3cemA:
undetectable
6hzpA-3cemA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dan CYTOCHROME P450 74A2

(Parthenium
argentatum)
PF00067
(p450)
4 TYR A 335
VAL A 433
ILE A 324
GLU A 325
None
0.98A 6hzpA-3danA:
undetectable
6hzpA-3danA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5y TRMH FAMILY RNA
METHYLTRANSFERASE


(Burkholderia
pseudomallei)
PF00588
(SpoU_methylase)
4 ASN A  14
PRO A  13
ILE A  11
GLU A 104
None
1.04A 6hzpA-3e5yA:
undetectable
6hzpA-3e5yA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1w MANNOSE-6-PHOSPHATE
ISOMERASE


(Salmonella
enterica)
PF01238
(PMI_typeI)
4 VAL A   8
ASN A  10
GLN A  30
PRO A  32
None
1.09A 6hzpA-3h1wA:
undetectable
6hzpA-3h1wA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h84 ATPASE GET3

(Saccharomyces
cerevisiae)
PF02374
(ArsA_ATPase)
4 ASN A 339
ASN A 279
PRO A 340
ILE A 341
None
1.08A 6hzpA-3h84A:
undetectable
6hzpA-3h84A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvy CYSTATHIONINE
BETA-LYASE FAMILY
PROTEIN, YNBB
B.SUBTILIS ORTHOLOG


(Clostridium
acetobutylicum)
PF06838
(Met_gamma_lyase)
4 TYR A 187
VAL A 375
GLN A 405
ILE A 348
None
1.01A 6hzpA-3hvyA:
undetectable
6hzpA-3hvyA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzr TRYPTOPHANYL-TRNA
SYNTHETASE


(Entamoeba
histolytica)
PF00579
(tRNA-synt_1b)
4 VAL A 172
GLN A  83
PRO A 199
ILE A 201
None
1.06A 6hzpA-3hzrA:
undetectable
6hzpA-3hzrA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivu HOMOCITRATE
SYNTHASE,
MITOCHONDRIAL


(Schizosaccharomyces
pombe)
PF00682
(HMGL-like)
5 VAL A 300
ASN A 306
PRO A 303
ILE A 302
GLU A 291
None
1.16A 6hzpA-3ivuA:
undetectable
6hzpA-3ivuA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2j PROTEIN VP1
PROTEIN VP3


(Enterovirus B;
Enterovirus B)
PF00073
(Rhv)
PF00073
(Rhv)
4 VAL B  94
GLN B  81
ASN A 217
ILE A 216
None
0.86A 6hzpA-3j2jB:
undetectable
6hzpA-3j2jB:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1i FLAGELLAR PROTEIN

(Helicobacter
pylori)
PF02561
(FliS)
4 VAL A  96
ASN A  95
ASN A  55
ILE A  51
None
1.08A 6hzpA-3k1iA:
4.4
6hzpA-3k1iA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1u BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE


(Clostridium
acetobutylicum)
PF04616
(Glyco_hydro_43)
4 GLN A 299
ASN A   8
PRO A   9
ILE A  10
None
0.81A 6hzpA-3k1uA:
undetectable
6hzpA-3k1uA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
4 TYR A 515
VAL A 517
ASN A 564
GLN A 593
None
0.85A 6hzpA-3lk6A:
2.1
6hzpA-3lk6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lv4 GLYCOSIDE HYDROLASE
YXIA


(Bacillus
licheniformis)
PF04616
(Glyco_hydro_43)
PF16369
(GH43_C)
4 ASN A  86
PRO A  85
ILE A  84
GLU A  90
None
0.90A 6hzpA-3lv4A:
undetectable
6hzpA-3lv4A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nk7 23S RRNA
METHYLTRANSFERASE


(Streptomyces
actuosus)
PF00588
(SpoU_methylase)
PF04705
(TSNR_N)
4 VAL A  81
ASN A   9
ILE A   7
GLU A   3
None
1.07A 6hzpA-3nk7A:
undetectable
6hzpA-3nk7A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3noj 4-CARBOXY-4-HYDROXY-
2-OXOADIPATE
ALDOLASE/OXALOACETAT
E DECARBOXYLASE


(Pseudomonas
putida)
PF03737
(RraA-like)
4 VAL A 153
ASN A 154
PRO A 166
ILE A  15
None
1.04A 6hzpA-3nojA:
undetectable
6hzpA-3nojA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nx6 10KDA CHAPERONIN

(Xanthomonas
oryzae)
PF00166
(Cpn10)
4 TYR A  82
VAL A  41
PRO A  14
ILE A  15
None
0.96A 6hzpA-3nx6A:
undetectable
6hzpA-3nx6A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o9p PERIPLASMIC MUREIN
PEPTIDE-BINDING
PROTEIN


(Escherichia
coli)
PF00496
(SBP_bac_5)
4 TYR A 506
VAL A 504
ASN A 500
ASN A  51
None
0.92A 6hzpA-3o9pA:
undetectable
6hzpA-3o9pA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opw DNA
DAMAGE-RESPONSIVE
TRANSCRIPTIONAL
REPRESSOR RPH1


(Saccharomyces
cerevisiae)
PF02373
(JmjC)
PF02375
(JmjN)
4 VAL A  43
GLN A 298
PRO A 259
ILE A 258
None
1.11A 6hzpA-3opwA:
undetectable
6hzpA-3opwA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qiv SHORT-CHAIN
DEHYDROGENASE OR
3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE


(Mycobacterium
avium)
PF13561
(adh_short_C2)
4 VAL A 159
ASN A 162
ASN A 240
ILE A 238
None
1.08A 6hzpA-3qivA:
undetectable
6hzpA-3qivA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)


(Doryteuthis
pealeii)
PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like)
4 VAL A 605
ASN A 724
ILE A 722
GLU A 672
None
0.96A 6hzpA-3qr1A:
undetectable
6hzpA-3qr1A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tfj GCVT-LIKE
AMINOMETHYLTRANSFERA
SE PROTEIN


(Candidatus
Pelagibacter
ubique)
PF01571
(GCV_T)
PF08669
(GCV_T_C)
4 VAL A 106
ASN A 107
ASN A  33
ILE A 123
None
1.08A 6hzpA-3tfjA:
undetectable
6hzpA-3tfjA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugv ENOLASE

(alpha
proteobacterium
BAL199)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 TYR A  55
GLN A 205
ASN A 255
GLU A 229
None
1.09A 6hzpA-3ugvA:
undetectable
6hzpA-3ugvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujh GLUCOSE-6-PHOSPHATE
ISOMERASE


(Toxoplasma
gondii)
PF00342
(PGI)
4 TYR A 293
GLN A 417
PRO A 484
ILE A 487
None
0.79A 6hzpA-3ujhA:
undetectable
6hzpA-3ujhA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ukf UDP-GALACTOPYRANOSE
MUTASE


(Aspergillus
fumigatus)
PF13450
(NAD_binding_8)
4 TYR A  69
VAL A 487
ASN A 488
ASN A 457
None
None
None
GDU  A 802 ( 4.0A)
1.07A 6hzpA-3ukfA:
undetectable
6hzpA-3ukfA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsc PROTEIN CYSO

(Aeropyrum
pernix)
PF00291
(PALP)
4 VAL A 126
ASN A 120
GLN A 245
GLU A 241
None
1.05A 6hzpA-3vscA:
undetectable
6hzpA-3vscA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a7k ALDOS-2-ULOSE
DEHYDRATASE


(Phanerochaete
chrysosporium)
no annotation 4 TYR A 284
VAL A 277
PRO A 221
ILE A 219
None
1.09A 6hzpA-4a7kA:
undetectable
6hzpA-4a7kA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7g CATALASE

(Corynebacterium
glutamicum)
PF00199
(Catalase)
PF06628
(Catalase-rel)
4 TYR A 132
VAL A 370
ASN A 371
ASN A 333
None
1.11A 6hzpA-4b7gA:
undetectable
6hzpA-4b7gA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dwq TRNA-SPLICING LIGASE
RTCB


(Pyrococcus
horikoshii)
PF01139
(RtcB)
4 TYR A 248
VAL A 244
PRO A  89
ILE A  92
PO4  A 507 ( 4.8A)
None
None
None
0.95A 6hzpA-4dwqA:
undetectable
6hzpA-4dwqA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fk7 PUTATIVE
ADP-RIBOSYLTRANSFERA
SE CERTHRAX


(Bacillus cereus)
PF03496
(ADPrib_exo_Tox)
4 TYR A 442
VAL A 463
GLN A 382
ILE A 409
None
1.07A 6hzpA-4fk7A:
undetectable
6hzpA-4fk7A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxd DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT A


(Saccharomyces
cerevisiae)
PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1)
4 TYR A 799
VAL A 486
ASN A 480
GLU A 361
None
1.11A 6hzpA-4fxdA:
undetectable
6hzpA-4fxdA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3s GLUTAMINE-TRNA
LIGASE


(Saccharomyces
cerevisiae)
PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C)
PF04557
(tRNA_synt_1c_R2)
4 TYR A 706
VAL A 733
ILE A 796
GLU A 789
None
1.06A 6hzpA-4h3sA:
undetectable
6hzpA-4h3sA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb4 EXPORTIN-1

(Saccharomyces
cerevisiae)
PF03810
(IBN_N)
PF08389
(Xpo1)
PF08767
(CRM1_C)
4 TYR C 645
GLN C 720
ASN C 706
ILE C 702
None
1.07A 6hzpA-4hb4C:
1.9
6hzpA-4hb4C:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ikv DI-TRIPEPTIDE ABC
TRANSPORTER
(PERMEASE)


(Geobacillus
kaustophilus)
PF00854
(PTR2)
7 TYR A  40
ASN A 166
GLN A 309
ASN A 342
PRO A 343
ILE A 346
GLU A 413
None
0.37A 6hzpA-4ikvA:
52.8
6hzpA-4ikvA:
49.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqx KETOL-ACID
REDUCTOISOMERASE


(Slackia exigua)
PF01450
(IlvC)
PF07991
(IlvN)
4 VAL A 246
ASN A 258
ILE A 254
GLU A 269
None
1.08A 6hzpA-4kqxA:
undetectable
6hzpA-4kqxA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l27 CYSTATHIONINE
BETA-SYNTHASE


(Homo sapiens)
no annotation 4 VAL B 118
ASN B 113
GLN B 243
GLU B 239
None
1.10A 6hzpA-4l27B:
undetectable
6hzpA-4l27B:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB


(Mycobacterium
tuberculosis)
PF13416
(SBP_bac_8)
4 TYR A 131
VAL A 348
ASN A 332
PRO A 333
None
1.07A 6hzpA-4mfiA:
undetectable
6hzpA-4mfiA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5a PROTEIN EFR3

(Saccharomyces
cerevisiae)
no annotation 4 ASN A 314
PRO A 315
ILE A 316
GLU A 356
None
1.12A 6hzpA-4n5aA:
undetectable
6hzpA-4n5aA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5c CARGO-TRANSPORT
PROTEIN YPP1


(Saccharomyces
cerevisiae)
no annotation 4 ASN A 347
GLN A 274
ILE A 306
GLU A 307
None
1.07A 6hzpA-4n5cA:
undetectable
6hzpA-4n5cA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv2 MAOC FAMILY PROTEIN

(Mycolicibacterium
smegmatis)
PF01575
(MaoC_dehydratas)
4 ASN B  38
GLN B  49
PRO B  39
ILE B  40
None
0.93A 6hzpA-4rv2B:
undetectable
6hzpA-4rv2B:
17.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY


(Shewanella
oneidensis)
PF00854
(PTR2)
7 TYR A  29
VAL A 150
ASN A 151
ASN A 329
PRO A 330
ILE A 333
GLU A 402
None
0.61A 6hzpA-4tpgA:
38.9
6hzpA-4tpgA:
30.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4w6v DI-/TRIPEPTIDE
TRANSPORTER


(Yersinia
enterocolitica)
PF00854
(PTR2)
5 TYR A  35
ASN A 163
ASN A 344
ILE A 348
GLU A 420
None
0.72A 6hzpA-4w6vA:
44.3
6hzpA-4w6vA:
34.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxj GLUTAMATE RECEPTOR
IIB,GLUTAMATE
RECEPTOR IIB


(Drosophila
melanogaster)
PF10613
(Lig_chan-Glu_bd)
4 TYR A  68
ASN A  66
ASN A 180
GLU A 182
GLU  A 301 (-2.8A)
None
None
None
1.11A 6hzpA-4wxjA:
undetectable
6hzpA-4wxjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgt FRQ-INTERACTING RNA
HELICASE


(Neurospora
crassa)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch)
4 GLN A 647
ASN A 329
PRO A 328
ILE A 327
None
1.07A 6hzpA-4xgtA:
2.0
6hzpA-4xgtA:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xni DI-OR TRIPEPTIDE:H+
SYMPORTER


(Streptococcus
thermophilus)
PF00854
(PTR2)
6 TYR A  30
ASN A 156
ASN A 328
PRO A 329
ILE A 332
GLU A 400
None
0.79A 6hzpA-4xniA:
46.5
6hzpA-4xniA:
42.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xni DI-OR TRIPEPTIDE:H+
SYMPORTER


(Streptococcus
thermophilus)
PF00854
(PTR2)
4 VAL A 152
ASN A 156
ILE A 332
GLU A 400
None
0.96A 6hzpA-4xniA:
46.5
6hzpA-4xniA:
42.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xz3 ACYL-COA SYNTHETASE
(NDP FORMING)


(Candidatus
Korarchaeum
cryptofilum)
PF13380
(CoA_binding_2)
PF13607
(Succ_CoA_lig)
4 VAL A 379
ASN A 348
PRO A 349
ILE A 350
None
1.10A 6hzpA-4xz3A:
undetectable
6hzpA-4xz3A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BOTULINUM NEUROTOXIN
TYPE E,
NONTOXIC-NONHEMAGGLU
TININ COMPONENT,
NTNH


(Clostridium
botulinum)
PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C)
4 ASN B 892
ASN B 907
ILE B 909
GLU B 915
None
0.84A 6hzpA-4zktB:
2.4
6hzpA-4zktB:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d3m ENERGY-COUPLING
FACTOR TRANSPORTER
TRANSMEMBRANE
PROTEIN ECFT


(Lactobacillus
delbrueckii)
PF02361
(CbiQ)
4 TYR D  44
ASN D  40
GLN D  83
ASN D 108
None
1.00A 6hzpA-5d3mD:
undetectable
6hzpA-5d3mD:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g06 EXOSOME COMPLEX
COMPONENT SKI6


(Saccharomyces
cerevisiae)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
4 VAL B 189
GLN B  44
ASN B 141
ILE B 140
None
1.09A 6hzpA-5g06B:
undetectable
6hzpA-5g06B:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmp UNCONVENTIONAL
MYOSIN-VC


(Homo sapiens)
PF00063
(Myosin_head)
4 VAL A 341
GLN A 371
ASN A 375
PRO A 388
None
1.03A 6hzpA-5hmpA:
1.8
6hzpA-5hmpA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5huc 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE (DAHP)
SYNTHASE


(Corynebacterium
glutamicum)
PF01474
(DAHP_synth_2)
4 GLN A 457
ASN A 455
ILE A 437
GLU A 435
None
0.93A 6hzpA-5hucA:
undetectable
6hzpA-5hucA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuy MULTIDRUG EFFLUX
OUTER MEMBRANE
PROTEIN OPRN


(Pseudomonas
aeruginosa)
PF02321
(OEP)
4 GLN A 414
ASN A 173
ILE A 169
GLU A 418
None
0.65A 6hzpA-5iuyA:
4.0
6hzpA-5iuyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxl FLAGELLAR HOOK
PROTEIN FLGE


(Campylobacter
jejuni)
PF00460
(Flg_bb_rod)
PF06429
(Flg_bbr_C)
PF07196
(Flagellin_IN)
PF07559
(FlaE)
4 VAL A 522
ASN A 536
ASN A 538
ILE A 594
None
1.08A 6hzpA-5jxlA:
2.6
6hzpA-5jxlA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kvu ISOCITRATE
DEHYDROGENASE


(Mycobacterium
tuberculosis)
PF03971
(IDH)
4 VAL A 295
ASN A 296
PRO A 266
ILE A 267
None
1.04A 6hzpA-5kvuA:
undetectable
6hzpA-5kvuA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5maw FLAGELLAR PROTEIN
FLIS


(Bacillus
subtilis)
no annotation 4 TYR E  86
VAL E  90
ASN E  59
ILE E  55
None
0.80A 6hzpA-5mawE:
4.3
6hzpA-5mawE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy5 NEURONAL PAS
DOMAIN-CONTAINING
PROTEIN 1


(Mus musculus)
PF00010
(HLH)
PF00989
(PAS)
PF08447
(PAS_3)
4 VAL B  92
GLN B 155
ASN B 154
GLU B 156
None
0.77A 6hzpA-5sy5B:
undetectable
6hzpA-5sy5B:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tuk TETRACYCLINE
DESTRUCTASE TET(51)


(uncultured
bacterium)
PF01494
(FAD_binding_3)
4 VAL A 348
GLN A 304
ASN A 341
ILE A 374
None
1.12A 6hzpA-5tukA:
undetectable
6hzpA-5tukA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5una 7SK SNRNA
METHYLPHOSPHATE
CAPPING ENZYME


(Homo sapiens)
PF06859
(Bin3)
PF13847
(Methyltransf_31)
4 VAL A 561
ASN A 559
GLN A 414
ILE A 475
SAH  A 701 (-4.7A)
SAH  A 701 (-3.6A)
None
SAH  A 701 (-3.8A)
1.09A 6hzpA-5unaA:
undetectable
6hzpA-5unaA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)


(Lachnospiraceae
bacterium
NK4A179)
no annotation 4 VAL A 680
ASN A 683
GLN A1087
ILE A1080
IOD  A1510 ( 4.4A)
U  B  12 ( 3.1A)
None
None
1.02A 6hzpA-5wlhA:
undetectable
6hzpA-5wlhA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5y UNCHARACTERIZED
PROTEIN


(Pseudomonas
aeruginosa)
PF03739
(YjgP_YjgQ)
4 VAL F 254
GLN F  61
PRO F 122
ILE F 125
None
0.78A 6hzpA-5x5yF:
2.7
6hzpA-5x5yF:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsx CHITINASE

(Thermococcus
chitonophagus)
no annotation 4 ASN A 699
PRO A 695
ILE A 698
GLU A 649
None
1.05A 6hzpA-5xsxA:
undetectable
6hzpA-5xsxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1


(Arabidopsis
thaliana)
no annotation 4 TYR A 170
VAL A 166
ASN A 164
PRO A 383
None
1.02A 6hzpA-6bsuA:
undetectable
6hzpA-6bsuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei3 PROTON-DEPENDENT
OLIGOPEPTIDE
TRANSPORTER FAMILY
PROTEIN


(Xanthomonas
campestris)
no annotation 5 TYR A  34
ASN A 164
ASN A 350
PRO A 351
GLU A 425
None
0.43A 6hzpA-6ei3A:
38.7
6hzpA-6ei3A:
26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN


(Vibrio
cholerae;
Streptococcus
pyogenes)
no annotation 4 TYR A 709
VAL A 707
ASN A 677
ILE A 676
None
0.98A 6hzpA-6en3A:
undetectable
6hzpA-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exs PEPTIDE ABC
TRANSPORTER PERMEASE


(Staphylococcus
hominis)
no annotation 8 TYR A  41
VAL A 166
ASN A 167
GLN A 310
ASN A 347
PRO A 348
ILE A 351
GLU A 418
C3H  A 514 (-4.0A)
None
C3H  A 514 (-3.6A)
C3H  A 514 (-3.5A)
C3H  A 514 (-4.0A)
C3H  A 514 (-4.1A)
None
None
0.24A 6hzpA-6exsA:
62.6
6hzpA-6exsA:
undetectable