SIMILAR PATTERNS OF AMINO ACIDS FOR 6H1L_B_FJQB501_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a80 | 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE A (Corynebacteriumsp.) |
PF00248(Aldo_ket_red) | 5 | ALA A 91LEU A 94VAL A 102ILE A 136LEU A 127 | None | 1.29A | 6h1lB-1a80A:undetectable | 6h1lB-1a80A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bhy | P64K (Neisseriameningitidis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 401VAL A 416ALA A 409ALA A 272LEU A 406 | NoneNoneNoneFAD A 600 (-3.8A)None | 1.23A | 6h1lB-1bhyA:0.0 | 6h1lB-1bhyA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ez4 | LACTATEDEHYDROGENASE (Lactobacilluspentosus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ALA A 227LEU A 226VAL A 211ALA A 187ALA A 173 | None | 1.18A | 6h1lB-1ez4A:0.0 | 6h1lB-1ez4A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ffv | CUTL, MOLYBDOPROTEINOF CARBON MONOXIDEDEHYDROGENASE (Hydrogenophagapseudoflava) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 5 | VAL B 372VAL B 143THR B 374ALA B 154LEU B 150 | None | 1.23A | 6h1lB-1ffvB:0.0 | 6h1lB-1ffvB:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fvf | SEC1 (Doryteuthispealeii) |
PF00995(Sec1) | 5 | VAL A 186ILE A 173ALA A 170ALA A 208LEU A 206 | None | 1.22A | 6h1lB-1fvfA:0.0 | 6h1lB-1fvfA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ghs | 1,3-BETA-GLUCANASE (Hordeum vulgare) |
PF00332(Glyco_hydro_17) | 5 | ALA A 268LEU A 269VAL A 258VAL A 229ILE A 273 | None | 1.27A | 6h1lB-1ghsA:0.0 | 6h1lB-1ghsA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k0r | NUSA (Mycobacteriumtuberculosis) |
PF08529(NusA_N)PF13184(KH_5) | 5 | ALA A 290VAL A 280VAL A 294ALA A 275ALA A 310 | None | 1.00A | 6h1lB-1k0rA:undetectable | 6h1lB-1k0rA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kl7 | THREONINE SYNTHASE (Saccharomycescerevisiae) |
PF00291(PALP)PF14821(Thr_synth_N) | 5 | ALA A 127LEU A 128VAL A 131PHE A 135ALA A 238 | None | 1.00A | 6h1lB-1kl7A:0.0 | 6h1lB-1kl7A:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5p | FERREDOXIN (Trichomonasvaginalis) |
PF00111(Fer2) | 5 | LEU A 14PHE A 91ILE A 80ALA A 77LEU A 82 | None | 1.01A | 6h1lB-1l5pA:undetectable | 6h1lB-1l5pA:13.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzj | BETA-KETOACYLSYNTHASE III (Streptomycessp. R1128) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | ALA A 313LEU A 251VAL A 273ILE A 264ALA A 237 | None | 1.28A | 6h1lB-1mzjA:undetectable | 6h1lB-1mzjA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7k | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Aeropyrumpernix) |
PF01791(DeoC) | 5 | ALA A 186LEU A 185VAL A 182THR A 168ILE A 219 | None | 0.91A | 6h1lB-1n7kA:undetectable | 6h1lB-1n7kA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1olx | 2-OXOISOVALERATEDEHYDROGENASE BETASUBUNIT (Homo sapiens) |
PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ALA B 87LEU B 130THR B 131ILE B 43THR B 72 | NoneNone K B 502 (-4.4A)NoneNone | 1.19A | 6h1lB-1olxB:undetectable | 6h1lB-1olxB:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q0z | ACLACINOMYCINMETHYLESTERASE (Streptomycespurpurascens) |
PF00561(Abhydrolase_1) | 5 | ALA A 96VAL A 98ILE A 107ALA A 81ALA A 86 | None | 1.15A | 6h1lB-1q0zA:undetectable | 6h1lB-1q0zA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1re5 | 3-CARBOXY-CIS,CIS-MUCONATECYCLOISOMERASE (Pseudomonasputida) |
PF00206(Lyase_1)PF10397(ADSL_C) | 5 | ALA A 337LEU A 247ALA A 133THR A 135ALA A 345 | None | 1.31A | 6h1lB-1re5A:undetectable | 6h1lB-1re5A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x8v | CYTOCHROME P450 51 (Mycobacteriumtuberculosis) |
PF00067(p450) | 5 | ALA A 346LEU A 53VAL A 51VAL A 334ALA A 65 | None | 1.24A | 6h1lB-1x8vA:31.1 | 6h1lB-1x8vA:25.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zcz | BIFUNCTIONAL PURINEBIOSYNTHESIS PROTEINPURH (Thermotogamaritima) |
PF01808(AICARFT_IMPCHas)PF02142(MGS) | 5 | ALA A 243VAL A 240ALA A 279ALA A 207LEU A 256 | None | 1.17A | 6h1lB-1zczA:undetectable | 6h1lB-1zczA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2asb | TRANSCRIPTIONELONGATION PROTEINNUSA (Mycobacteriumtuberculosis) |
PF13184(KH_5) | 5 | ALA A 290VAL A 280VAL A 294ALA A 275ALA A 310 | NoneNoneNoneNone A B 8 ( 3.6A) | 0.95A | 6h1lB-2asbA:undetectable | 6h1lB-2asbA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ewm | (S)-1-PHENYLETHANOLDEHYDROGENASE (Azoarcus) |
PF13561(adh_short_C2) | 5 | ALA A 10VAL A 87THR A 13ILE A 19ALA A 45 | NoneNoneNoneNAD A 257 (-3.9A)None | 1.16A | 6h1lB-2ewmA:undetectable | 6h1lB-2ewmA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gs9 | HYPOTHETICAL PROTEINTT1324 (Thermusthermophilus) |
PF08241(Methyltransf_11) | 5 | LEU A 182VAL A 180ILE A 24ALA A 21THR A 17 | None | 1.18A | 6h1lB-2gs9A:undetectable | 6h1lB-2gs9A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hls | PROTEIN DISULFIDEOXIDOREDUCTASE (Aeropyrumpernix) |
PF13192(Thioredoxin_3) | 5 | VAL A 90PHE A 92VAL A 97ILE A 115LEU A 111 | None | 1.13A | 6h1lB-2hlsA:undetectable | 6h1lB-2hlsA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nrr | UVRABC SYSTEMPROTEIN C (Thermotogamaritima) |
PF08459(UvrC_HhH_N) | 5 | ALA A 455VAL A 462VAL A 428ILE A 439ALA A 438 | None | 1.15A | 6h1lB-2nrrA:undetectable | 6h1lB-2nrrA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ogx | MOLYBDENUM STORAGEPROTEIN SUBUNITALPHA (Azotobactervinelandii) |
PF00696(AA_kinase) | 5 | ALA A 231LEU A 232ALA A 178ALA A 151LEU A 176 | None | 0.98A | 6h1lB-2ogxA:undetectable | 6h1lB-2ogxA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ogx | MOLYBDENUM STORAGEPROTEIN SUBUNITALPHA (Azotobactervinelandii) |
PF00696(AA_kinase) | 5 | ALA A 231LEU A 232VAL A 235ALA A 178ALA A 151 | None | 0.95A | 6h1lB-2ogxA:undetectable | 6h1lB-2ogxA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pig | PUTATIVE TRANSFERASE (Salmonellaenterica) |
no annotation | 5 | ALA A 101VAL A 96ILE A 74ALA A 107LEU A 86 | None | 1.12A | 6h1lB-2pigA:undetectable | 6h1lB-2pigA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9g | CYTOCHROME P450 46A1 (Homo sapiens) |
PF00067(p450) | 6 | PHE A 121VAL A 126ILE A 301ALA A 302THR A 306ALA A 367 | NoneHEM A 505 ( 3.8A)NoneHEM A 505 (-3.7A)HEM A 505 (-3.7A)HEM A 505 (-3.5A) | 0.40A | 6h1lB-2q9gA:41.9 | 6h1lB-2q9gA:26.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qym | PHOSPHODIESTERASE 4C (Homo sapiens) |
PF00233(PDEase_I) | 5 | LEU A 405VAL A 409THR A 505ALA A 514THR A 300 | None | 1.28A | 6h1lB-2qymA:undetectable | 6h1lB-2qymA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rag | DIPEPTIDASE (Caulobactervibrioides) |
PF01244(Peptidase_M19) | 5 | ALA A 193LEU A 192VAL A 164ILE A 99ALA A 182 | None | 1.06A | 6h1lB-2ragA:undetectable | 6h1lB-2ragA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rjo | TWIN-ARGININETRANSLOCATIONPATHWAY SIGNALPROTEIN (Paraburkholderiaphytofirmans) |
PF13407(Peripla_BP_4) | 5 | LEU A 164VAL A 281VAL A 236ILE A 248ALA A 247 | None | 1.27A | 6h1lB-2rjoA:undetectable | 6h1lB-2rjoA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z06 | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA0625 (Thermusthermophilus) |
PF13277(YmdB) | 5 | ALA A 34VAL A 32ILE A 25ALA A 17LEU A 22 | None | 1.23A | 6h1lB-2z06A:undetectable | 6h1lB-2z06A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zu8 | MANNOSYL-3-PHOSPHOGLYCERATE SYNTHASE (Pyrococcushorikoshii) |
PF09488(Osmo_MPGsynth) | 5 | ALA A 169VAL A 55ILE A 112ALA A 73LEU A 71 | GDD A 395 (-3.6A)NoneNoneNoneNone | 1.26A | 6h1lB-2zu8A:undetectable | 6h1lB-2zu8A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7y | E3 UBIQUITIN-PROTEINLIGASE NEDD4 (Homo sapiens) |
PF00168(C2) | 5 | LEU A 231VAL A 206VAL A 191ALA A 127LEU A 246 | None | 1.10A | 6h1lB-3b7yA:undetectable | 6h1lB-3b7yA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cai | POSSIBLEAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00266(Aminotran_5) | 5 | ALA A 131VAL A 133ILE A 119ALA A 120ALA A 95 | None | 1.05A | 6h1lB-3caiA:undetectable | 6h1lB-3caiA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmm | UBIQUITIN-ACTIVATINGENZYME E1 1 (Saccharomycescerevisiae) |
PF00899(ThiF)PF09358(E1_UFD)PF10585(UBA_e1_thiolCys)PF16190(E1_FCCH)PF16191(E1_4HB) | 5 | LEU A 439VAL A 437PHE A 538THR A 540LEU A 458 | None | 1.15A | 6h1lB-3cmmA:undetectable | 6h1lB-3cmmA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dla | GLUTAMINE-DEPENDENTNAD(+) SYNTHETASE (Mycobacteriumtuberculosis) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 5 | LEU A 116VAL A 109ALA A 46ALA A 163LEU A 171 | None | 1.14A | 6h1lB-3dlaA:undetectable | 6h1lB-3dlaA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ep7 | S-ADENOSYLMETHIONINEDECARBOXYLASE ALPHACHAIN (Homo sapiens) |
PF01536(SAM_decarbox) | 5 | VAL A 274PHE A 275ILE A 242THR A 257LEU A 212 | None | 1.02A | 6h1lB-3ep7A:undetectable | 6h1lB-3ep7A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fcr | PUTATIVEAMINOTRANSFERASE (Ruegeria sp.TM1040) |
PF00202(Aminotran_3) | 5 | ALA A 352VAL A 262THR A 263ILE A 234ALA A 56 | NoneLLP A 288 (-4.4A)NoneNoneNone | 1.10A | 6h1lB-3fcrA:undetectable | 6h1lB-3fcrA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gka | N-ETHYLMALEIMIDEREDUCTASE (Burkholderiapseudomallei) |
PF00724(Oxidored_FMN) | 5 | ALA A 211LEU A 214VAL A 180ILE A 222ALA A 221 | None | 1.27A | 6h1lB-3gkaA:undetectable | 6h1lB-3gkaA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjr | EXTRACELLULAR SERINEPROTEASE (Aeromonassobria) |
PF00082(Peptidase_S8)PF01483(P_proprotein) | 5 | ALA A 62LEU A 59ALA A 124ALA A 347LEU A 68 | None | 1.25A | 6h1lB-3hjrA:undetectable | 6h1lB-3hjrA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i57 | MUCUS BINDINGPROTEIN (Lactobacillusreuteri) |
no annotation | 5 | VAL A 6PHE A 53THR A 34ILE A 30LEU A 22 | None | 1.20A | 6h1lB-3i57A:undetectable | 6h1lB-3i57A:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ikm | DNA POLYMERASESUBUNIT GAMMA-1 (Homo sapiens) |
PF00476(DNA_pol_A) | 5 | ALA A 425LEU A 428VAL A 266ALA A 153LEU A 151 | None | 1.26A | 6h1lB-3ikmA:undetectable | 6h1lB-3ikmA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3io1 | AMINOBENZOYL-GLUTAMATE UTILIZATIONPROTEIN (Klebsiellapneumoniae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ALA A 51LEU A 50VAL A 98PHE A 179ALA A 161 | None | 1.32A | 6h1lB-3io1A:undetectable | 6h1lB-3io1A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m7f | E3 UBIQUITIN-PROTEINLIGASE NEDD4 (Mus musculus) |
PF00168(C2) | 5 | LEU B 231VAL B 206VAL B 191ALA B 127LEU B 246 | None | 1.12A | 6h1lB-3m7fB:undetectable | 6h1lB-3m7fB:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o90 | NICOTINAMIDASE (Streptococcuspneumoniae) |
PF00857(Isochorismatase) | 5 | ALA A 54PHE A 14THR A 11THR A 140ALA A 108 | None | 1.13A | 6h1lB-3o90A:undetectable | 6h1lB-3o90A:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pyz | BIFUNCTIONALFOLYLPOLYGLUTAMATESYNTHASE/DIHYDROFOLATE SYNTHASE (Yersinia pestis) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | PHE A 192ILE A 166ALA A 165THR A 272ALA A 275 | None | 1.25A | 6h1lB-3pyzA:undetectable | 6h1lB-3pyzA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qta | CHEMOTAXIS PROTEINCHEC (Haloarculamarismortui) |
PF13690(CheX) | 5 | ALA A 32LEU A 28ALA A 175THR A 83LEU A 90 | None | 0.97A | 6h1lB-3qtaA:undetectable | 6h1lB-3qtaA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r38 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Listeriamonocytogenes) |
PF00275(EPSP_synthase) | 5 | VAL A 312ILE A 377THR A 387ALA A 383LEU A 381 | None | 1.00A | 6h1lB-3r38A:undetectable | 6h1lB-3r38A:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sc3 | PUTATIVE DNAREPLICATIONREGULATOR HDA (Shewanellaamazonensis) |
PF00308(Bac_DnaA) | 5 | LEU A 241VAL A 235THR A 211ALA A 206LEU A 201 | None | 1.12A | 6h1lB-3sc3A:undetectable | 6h1lB-3sc3A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | LEU A 762VAL A 744PHE A 725ILE A 708THR A 734 | None | 1.07A | 6h1lB-3szeA:undetectable | 6h1lB-3szeA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t5t | PUTATIVEGLYCOSYLTRANSFERASE (Streptomyceshygroscopicus) |
PF00982(Glyco_transf_20) | 5 | VAL A 227PHE A 223ILE A 212ALA A 166LEU A 207 | None | 1.32A | 6h1lB-3t5tA:undetectable | 6h1lB-3t5tA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxy | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Rhodobactersphaeroides) |
PF13561(adh_short_C2) | 5 | ALA A 223VAL A 127VAL A 11ILE A 18ALA A 25 | None | 1.07A | 6h1lB-3uxyA:undetectable | 6h1lB-3uxyA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zjc | GTPASE IMAP FAMILYMEMBER 7 (Homo sapiens) |
PF04548(AIG1) | 5 | ALA A 94VAL A 128VAL A 98THR A 27LEU A 185 | None | 1.11A | 6h1lB-3zjcA:undetectable | 6h1lB-3zjcA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpm | LATHERIN (Equus caballus) |
PF01273(LBP_BPI_CETP) | 5 | ALA A 173PHE A 24THR A 178ILE A 88LEU A 135 | None | 1.27A | 6h1lB-3zpmA:undetectable | 6h1lB-3zpmA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bru | ATP-DEPENDENT RNAHELICASE DHH1 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ALA A 179VAL A 175THR A 148ILE A 119LEU A 118 | None | 1.27A | 6h1lB-4bruA:undetectable | 6h1lB-4bruA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ddw | REVERSE GYRASE (Thermotogamaritima) |
PF00270(DEAD)PF01131(Topoisom_bac)PF01751(Toprim) | 5 | ALA A 258VAL A 278PHE A 270ILE A 215LEU A 209 | None | 1.03A | 6h1lB-4ddwA:undetectable | 6h1lB-4ddwA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f4c | MULTIDRUG RESISTANCEPROTEIN PGP-1 (Caenorhabditiselegans) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | ALA A 596LEU A 597ALA A 495ALA A 564LEU A 569 | None | 1.03A | 6h1lB-4f4cA:undetectable | 6h1lB-4f4cA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6c | AUSA REDUCTASEDOMAIN PROTEIN (Staphylococcusaureus) |
PF07993(NAD_binding_4) | 5 | ALA A2217VAL A2214VAL A2156THR A2153ILE A2168 | None | 1.28A | 6h1lB-4f6cA:undetectable | 6h1lB-4f6cA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6l | AUSA REDUCTASEDOMAIN PROTEIN (Staphylococcusaureus) |
no annotation | 5 | ALA B2217VAL B2214VAL B2156THR B2153ALA B2165 | None | 1.26A | 6h1lB-4f6lB:undetectable | 6h1lB-4f6lB:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6l | AUSA REDUCTASEDOMAIN PROTEIN (Staphylococcusaureus) |
no annotation | 5 | ALA B2217VAL B2214VAL B2156THR B2153ILE B2168 | None | 1.24A | 6h1lB-4f6lB:undetectable | 6h1lB-4f6lB:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6t | MOLYBDENUM STORAGEPROTEIN SUBUNITALPHA (Azotobactervinelandii) |
PF00696(AA_kinase) | 5 | ALA A 231LEU A 232ALA A 178ALA A 151LEU A 176 | None | 0.98A | 6h1lB-4f6tA:undetectable | 6h1lB-4f6tA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6t | MOLYBDENUM STORAGEPROTEIN SUBUNITALPHA (Azotobactervinelandii) |
PF00696(AA_kinase) | 5 | ALA A 231LEU A 232VAL A 235ALA A 178ALA A 151 | None | 0.95A | 6h1lB-4f6tA:undetectable | 6h1lB-4f6tA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f7z | RAP GUANINENUCLEOTIDE EXCHANGEFACTOR 4 (Mus musculus) |
PF00027(cNMP_binding)PF00610(DEP)PF00617(RasGEF)PF00618(RasGEF_N) | 5 | ALA A 940VAL A 943PHE A 770VAL A 773LEU A 909 | None | 1.29A | 6h1lB-4f7zA:undetectable | 6h1lB-4f7zA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdg | MINICHROMOSOMEMAINTENANCE PROTEINMCM (Sulfolobussolfataricus) |
no annotation | 5 | ALA B 396VAL B 426ILE B 417ALA B 416ALA B 371 | None | 1.09A | 6h1lB-4fdgB:undetectable | 6h1lB-4fdgB:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwg | TTC1975 PEPTIDASE (Meiothermustaiwanensis) |
PF05362(Lon_C)PF13654(AAA_32) | 5 | LEU A 312VAL A 358ILE A 354ALA A 325LEU A 330 | None | 0.93A | 6h1lB-4fwgA:undetectable | 6h1lB-4fwgA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ggj | MITOCHONDRIALCARDIOLIPINHYDROLASE (Mus musculus) |
PF13091(PLDc_2) | 5 | VAL A 183PHE A 43ILE A 176ALA A 175ALA A 97 | None | 1.09A | 6h1lB-4ggjA:undetectable | 6h1lB-4ggjA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpr | UBIQUITIN-CONJUGATING ENZYME FAMILYPROTEIN (Entamoebahistolytica) |
PF00179(UQ_con) | 5 | VAL A 73PHE A 69THR A 71ILE A 106LEU A 110 | None | 1.27A | 6h1lB-4gprA:undetectable | 6h1lB-4gprA:16.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxt | DE NOVO PROTEINOR329 (syntheticconstruct) |
PF00514(Arm) | 5 | ALA A 191VAL A 172ILE A 205ALA A 204ALA A 156 | None | 1.12A | 6h1lB-4hxtA:undetectable | 6h1lB-4hxtA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kw2 | UNCHARACTERIZEDPROTEIN (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 5 | VAL A 207VAL A 127THR A 128ILE A 99ALA A 124 | None | 1.17A | 6h1lB-4kw2A:undetectable | 6h1lB-4kw2A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0p | RIBOSE-PHOSPHATEPYROPHOSPHOKINASE 1 (Homo sapiens) |
PF13793(Pribosyltran_N)PF14572(Pribosyl_synth) | 5 | ALA A 241LEU A 237VAL A 244PHE A 266ILE A 229 | None | 1.22A | 6h1lB-4m0pA:undetectable | 6h1lB-4m0pA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ni5 | OXIDOREDUCTASE,SHORT-CHAINDEHYDROGENASE/REDUCTASE FAMILY PROTEIN (Brucella suis) |
PF13561(adh_short_C2) | 5 | ALA A 225VAL A 136VAL A 10ILE A 17ALA A 24 | None | 0.99A | 6h1lB-4ni5A:undetectable | 6h1lB-4ni5A:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nzs | BETA-KETOTHIOLASEBKTB (Cupriavidusnecator) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ALA A 42LEU A 39VAL A 77THR A 109ALA A 112 | None | 1.04A | 6h1lB-4nzsA:undetectable | 6h1lB-4nzsA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqj | PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A 647LEU A 648THR A 601ILE A 665ALA A 612 | None | 1.24A | 6h1lB-4oqjA:undetectable | 6h1lB-4oqjA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj6 | LEUCYL-CYSTINYLAMINOPEPTIDASE (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | LEU A 251VAL A 172THR A 204ALA A 244ALA A 232 | None | 1.04A | 6h1lB-4pj6A:undetectable | 6h1lB-4pj6A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wl2 | PUTATIVE EXPORTEDCHOLOYLGLYCINEHYDROLASE (Pectobacteriumatrosepticum) |
PF02275(CBAH) | 5 | ALA A 332VAL A 301ILE A 59ALA A 60THR A 29 | None | 1.27A | 6h1lB-4wl2A:undetectable | 6h1lB-4wl2A:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x57 | UBIQUITIN-CONJUGATING ENZYME E2 8 (Arabidopsisthaliana) |
PF00179(UQ_con) | 5 | VAL A 73PHE A 69THR A 71ILE A 106LEU A 110 | None | 1.32A | 6h1lB-4x57A:undetectable | 6h1lB-4x57A:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb6 | ALPHA-D-RIBOSE1-METHYLPHOSPHONATE5-PHOSPHATE C-PLYASE (Escherichiacoli) |
PF06007(PhnJ) | 5 | PHE D 86VAL D 89THR D 90ILE D 53LEU D 12 | None | 1.17A | 6h1lB-4xb6D:undetectable | 6h1lB-4xb6D:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcg | THERMOSOME SUBUNITBETA (Sulfolobussolfataricus) |
PF00118(Cpn60_TCP1) | 5 | ALA B 375VAL B 372ILE B 301ALA B 249LEU B 333 | None | 1.13A | 6h1lB-4xcgB:undetectable | 6h1lB-4xcgB:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xkm | XYLOSE ISOMERASE (Bacteroidesthetaiotaomicron) |
no annotation | 5 | ALA A 357THR A 53ALA A 47THR A 338ALA A 299 | None | 1.32A | 6h1lB-4xkmA:undetectable | 6h1lB-4xkmA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yg7 | SERINE/THREONINE-PROTEIN KINASE HIPA (Escherichiacoli) |
PF07804(HipA_C)PF13657(Couple_hipA) | 5 | LEU D 129VAL D 128ILE D 149ALA D 232LEU D 160 | None | 1.24A | 6h1lB-4yg7D:undetectable | 6h1lB-4yg7D:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8q | PUTATIVE RETAININGB-GLYCOSIDASE (Saccharophagusdegradans) |
PF00150(Cellulase) | 5 | ALA A 289PHE A 58ILE A 224ALA A 182LEU A 226 | None | 1.28A | 6h1lB-5a8qA:undetectable | 6h1lB-5a8qA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6s | EPOXYQUEUOSINEREDUCTASE (Streptococcusthermophilus) |
PF08331(DUF1730)PF13484(Fer4_16) | 5 | LEU A 172PHE A 21THR A 66ILE A 19ALA A 113 | None | 1.06A | 6h1lB-5d6sA:undetectable | 6h1lB-5d6sA:23.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 6 | ALA A 74LEU A 75VAL A 78THR A 88THR A 268ALA A 328 | NoneNoneNoneNoneHEM A 501 (-3.4A)HEM A 501 ( 3.8A) | 0.40A | 6h1lB-5e78A:55.5 | 6h1lB-5e78A:99.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 5 | ILE A 263ALA A 264THR A 268ALA A 328LEU A 437 | NoneHEM A 501 (-3.6A)HEM A 501 (-3.4A)HEM A 501 ( 3.8A)None | 0.80A | 6h1lB-5e78A:55.5 | 6h1lB-5e78A:99.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 5 | THR A 88ALA A 264THR A 268ALA A 328LEU A 437 | NoneHEM A 501 (-3.6A)HEM A 501 (-3.4A)HEM A 501 ( 3.8A)None | 0.81A | 6h1lB-5e78A:55.5 | 6h1lB-5e78A:99.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 5 | VAL A 78THR A 88THR A 268ALA A 328LEU A 437 | NoneNoneHEM A 501 (-3.4A)HEM A 501 ( 3.8A)None | 1.11A | 6h1lB-5e78A:55.5 | 6h1lB-5e78A:99.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej2 | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | ALA A 205LEU A 162VAL A 144ILE A 201ALA A 191 | None | 0.95A | 6h1lB-5ej2A:undetectable | 6h1lB-5ej2A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5exe | OXALATEOXIDOREDUCTASESUBUNIT DELTA (Moorellathermoacetica) |
PF00037(Fer4)PF01558(POR) | 5 | ALA B 19VAL B 17VAL B 112ALA B 173ALA B 140 | None | 1.09A | 6h1lB-5exeB:undetectable | 6h1lB-5exeB:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fv0 | ESSC (Geobacillusthermodenitrificans) |
PF01580(FtsK_SpoIIIE) | 5 | ALA A1434VAL A1283THR A1438ALA A1447LEU A1445 | None | 1.04A | 6h1lB-5fv0A:undetectable | 6h1lB-5fv0A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjl | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Streptococcusporcinus) |
PF01791(DeoC) | 5 | ALA A 22LEU A 23THR A 60ILE A 77ALA A 76 | None | 1.22A | 6h1lB-5hjlA:undetectable | 6h1lB-5hjlA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iaa | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME 5 (Homo sapiens) |
PF00899(ThiF) | 5 | LEU A 273VAL A 269ILE A 78ALA A 77LEU A 92 | None | 0.99A | 6h1lB-5iaaA:undetectable | 6h1lB-5iaaA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ic9 | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF08625(Utp13) | 5 | VAL B 829PHE B 774VAL B 777ILE B 758LEU B 798 | None | 0.91A | 6h1lB-5ic9B:undetectable | 6h1lB-5ic9B:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lpe | KALLIKREIN-10 (Homo sapiens) |
PF00089(Trypsin) | 5 | VAL A 217THR A 144ALA A 43THR A 54LEU A 213 | SO4 A 301 (-4.1A)NoneNoneNoneNone | 1.21A | 6h1lB-5lpeA:undetectable | 6h1lB-5lpeA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd5 | TRANSKETOLASE (Chlamydomonasreinhardtii) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ALA A 309VAL A 314ILE A 70ALA A 66LEU A 319 | None | 1.31A | 6h1lB-5nd5A:undetectable | 6h1lB-5nd5A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u25 | DIHYDROLIPOAMIDEDEHYDROGENASE (E3COMPONENT OFPYRUVATE AND2-OXOGLUTARATEDEHYDROGENASECOMPLEXES) (Neisseriagonorrhoeae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 396VAL A 411ALA A 404ALA A 267LEU A 401 | NoneNoneNoneFAD A 601 (-3.8A)None | 1.32A | 6h1lB-5u25A:undetectable | 6h1lB-5u25A:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v44 | SACSIN (Homo sapiens) |
no annotation | 5 | ALA A 303LEU A 307VAL A 306VAL A 313ALA A 121 | None | 1.04A | 6h1lB-5v44A:undetectable | 6h1lB-5v44A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vtm | TYPE II SECRETIONSYSTEM PROTEIN K (Pseudomonasaeruginosa) |
no annotation | 5 | LEU X 132THR X 135ILE X 233ALA X 238ALA X 222 | None | 1.02A | 6h1lB-5vtmX:undetectable | 6h1lB-5vtmX:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wso | NS3 HELICASE (Pestivirus A) |
no annotation | 5 | ALA A 676LEU A 677VAL A 680VAL A 479THR A 547 | None | 0.92A | 6h1lB-5wsoA:undetectable | 6h1lB-5wsoA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xya | - (-) |
no annotation | 5 | ALA A 340VAL A 373ILE A 365ALA A 364ALA A 331 | None | 1.16A | 6h1lB-5xyaA:undetectable | 6h1lB-5xyaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b5v | TRANSIENT RECEPTORPOTENTIAL CATIONCHANNEL SUBFAMILY VMEMBER 5 (Oryctolaguscuniculus) |
no annotation | 5 | ALA A 498PHE A 504THR A 533ILE A 565ALA A 566 | None | 0.81A | 6h1lB-6b5vA:undetectable | 6h1lB-6b5vA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fa5 | PUTATIVE MRNASPLICING FACTOR (Chaetomiumthermophilum) |
no annotation | 5 | LEU A 444THR A 438ILE A 448THR A 349ALA A 347 | None | 1.08A | 6h1lB-6fa5A:undetectable | 6h1lB-6fa5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fik | POLYKETIDE SYNTHASE (Cercosporanicotianae) |
no annotation | 5 | ALA A 122LEU A 123VAL A 126VAL A 147THR A 144 | None | 1.00A | 6h1lB-6fikA:undetectable | 6h1lB-6fikA:undetectable |