SIMILAR PATTERNS OF AMINO ACIDS FOR 6GTQ_A_ACTA204_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5l UREASE (ALPHA
SUBUNIT)

(Klebsiella
aerogenes) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 LEU C 193
THR C 171
THR C 169
GLY C 158
 None
 1.13A 6gtqA-1a5lC:
0.7		 6gtqA-1a5lC:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ft9 CARBON MONOXIDE
OXIDATION SYSTEM
TRANSCRIPTION
REGULATOR

(Rhodospirillum
rubrum) 		PF13545
(HTH_Crp_2) 		4 LEU A  81
THR A  36
CYH A  80
GLY A  37
 None
 1.16A 6gtqA-1ft9A:
undetectable		 6gtqA-1ft9A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8t UDP-GALACTOPYRANOSE
MUTASE

(Escherichia
coli) 		PF03275
(GLF)
PF13450
(NAD_binding_8) 		4 LEU A 147
THR A 270
THR A 152
GLY A 150
 None
 1.15A 6gtqA-1i8tA:
0.0		 6gtqA-1i8tA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq4 50S RIBOSOMAL
PROTEIN L5

(Geobacillus
stearothermophilus) 		PF00281
(Ribosomal_L5)
PF00673
(Ribosomal_L5_C) 		4 LEU A 169
THR A 158
THR A 162
GLY A 126
 None
 1.28A 6gtqA-1iq4A:
1.2		 6gtqA-1iq4A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kpl PUTATIVE CLC FAMILY,
CHLORINE TRANSPORT
PROTEIN

(Salmonella
enterica) 		PF00654
(Voltage_CLC) 		4 LEU A 158
THR A  46
THR A 180
GLY A  43
 None
 1.21A 6gtqA-1kplA:
undetectable		 6gtqA-1kplA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ks9 2-DEHYDROPANTOATE
2-REDUCTASE

(Escherichia
coli) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 LEU A  61
THR A   4
THR A  54
GLY A  28
 None
 1.29A 6gtqA-1ks9A:
0.7		 6gtqA-1ks9A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5x XANTHINE
DEHYDROGENASE

(Bos taurus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 LEU A 900
CYH A 901
THR A 903
GLY A 868
 None
 0.88A 6gtqA-1n5xA:
0.7		 6gtqA-1n5xA:
8.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE

(Escherichia
coli) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 THR A 240
CYH A 243
THR A 238
GLY A 239
 CDM  A1284 ( 4.8A)
None
None
CDM  A1284 ( 4.2A)
 1.27A 6gtqA-1oj4A:
1.9		 6gtqA-1oj4A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE

(Bacillus
subtilis) 		PF01070
(FMN_dh) 		4 LEU A 242
THR A 238
THR A 332
GLY A  24
 None
 1.11A 6gtqA-1p0nA:
0.0		 6gtqA-1p0nA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v6u ENDO-1,4-BETA-D-XYLA
NASE

(Streptomyces
olivaceoviridis) 		PF00331
(Glyco_hydro_10)
PF00652
(Ricin_B_lectin) 		4 LEU A  96
THR A 100
THR A 146
GLY A  98
 None
 1.25A 6gtqA-1v6uA:
undetectable		 6gtqA-1v6uA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vaj HYPOTHETICAL PROTEIN
PH0010

(Pyrococcus
horikoshii) 		PF01871
(AMMECR1) 		4 LEU A 171
CYH A 166
THR A 165
GLY A 144
 None
 0.92A 6gtqA-1vajA:
undetectable		 6gtqA-1vajA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wst MULTIPLE SUBSTRATE
AMINOTRANSFERASE

(Thermococcus
profundus) 		PF00155
(Aminotran_1_2) 		4 THR A 111
CYH A 286
THR A  81
GLY A  84
 None
 1.26A 6gtqA-1wstA:
undetectable		 6gtqA-1wstA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xa6 BETA2-CHIMAERIN

(Homo sapiens) 		PF00017
(SH2)
PF00130
(C1_1)
PF00620
(RhoGAP) 		4 LEU A 236
THR A 126
THR A 131
GLY A 128
 None
 1.02A 6gtqA-1xa6A:
undetectable		 6gtqA-1xa6A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq7 HYPOTHETICAL PROTEIN
MM0484

(Methanosarcina
mazei) 		PF01871
(AMMECR1) 		4 LEU A 166
CYH A 161
THR A 160
GLY A 139
 None
 0.91A 6gtqA-1zq7A:
undetectable		 6gtqA-1zq7A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3x IRON-RESPONSIVE
ELEMENT BINDING
PROTEIN 1

(Homo sapiens) 		PF00330
(Aconitase)
PF00694
(Aconitase_C) 		4 THR A 435
CYH A 437
THR A 438
GLY A 534
 None
SF4  A1000 (-2.3A)
None
None
 0.90A 6gtqA-2b3xA:
undetectable		 6gtqA-2b3xA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7y FAVIN BETA CHAIN
FAVIN ALPHA CHAIN

(Vicia faba;
Vicia faba) 		PF00139
(Lectin_legB)
PF00139
(Lectin_legB) 		4 LEU A 102
THR B 209
THR A  97
GLY A  99
 None
None
None
GLC  A 801 (-3.2A)
 1.24A 6gtqA-2b7yA:
undetectable		 6gtqA-2b7yA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bqp PROTEIN (PEA LECTIN)

(Pisum sativum) 		PF00139
(Lectin_legB) 		4 LEU A 101
THR A 214
THR A  96
GLY A  98
 None
None
None
GLC  A 337 ( 3.8A)
 1.21A 6gtqA-2bqpA:
undetectable		 6gtqA-2bqpA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2csn CASEIN KINASE-1

(Schizosaccharomyces
pombe) 		PF00069
(Pkinase) 		4 LEU A  62
CYH A  65
THR A  66
GLY A  67
 None
 1.25A 6gtqA-2csnA:
undetectable		 6gtqA-2csnA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4n DU

(Mason-Pfizer
monkey virus) 		PF00692
(dUTPase) 		4 LEU A 125
CYH A 126
THR A 128
GLY A 145
 None
 1.20A 6gtqA-2d4nA:
undetectable		 6gtqA-2d4nA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4n DU

(Mason-Pfizer
monkey virus) 		PF00692
(dUTPase) 		4 LEU A 125
THR A 144
CYH A 126
GLY A 145
 None
 1.17A 6gtqA-2d4nA:
undetectable		 6gtqA-2d4nA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D

(Methanothermobacter
thermautotrophicus) 		PF00710
(Asparaginase) 		4 LEU A 246
THR A 232
CYH A 234
THR A 200
 None
 1.04A 6gtqA-2d6fA:
undetectable		 6gtqA-2d6fA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2de6 FERREDOXIN COMPONENT
OF CARBAZOLE

(Pseudomonas
resinovorans) 		PF00355
(Rieske) 		4 THR D  42
CYH D  75
THR D  76
GLY D  77
 None
 1.23A 6gtqA-2de6D:
undetectable		 6gtqA-2de6D:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dix INTERFERON-INDUCIBLE
DOUBLE STRANDED
RNA-DEPENDENT
PROTEIN KINASE
ACTIVATOR A

(Homo sapiens) 		PF00035
(dsrm) 		4 LEU A  61
THR A  57
THR A  42
GLY A  56
 None
 1.23A 6gtqA-2dixA:
undetectable		 6gtqA-2dixA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE

(Streptomyces
clavuligerus) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 LEU A  81
THR A  80
THR A  86
GLY A  84
 None
 1.10A 6gtqA-2ihtA:
undetectable		 6gtqA-2ihtA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixd LMBE-RELATED PROTEIN

(Bacillus cereus) 		PF02585
(PIG-L) 		4 LEU A  70
THR A  68
CYH A  37
GLY A  35
 None
 1.21A 6gtqA-2ixdA:
undetectable		 6gtqA-2ixdA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j04 YDR362CP

(Saccharomyces
cerevisiae) 		no annotation 4 THR B 557
CYH B 644
THR B 645
GLY B 571
 None
 1.10A 6gtqA-2j04B:
undetectable		 6gtqA-2j04B:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjy ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE

(Francisella
tularensis) 		PF13561
(adh_short_C2) 		4 THR A 158
CYH A 106
THR A 108
GLY A 111
 None
 1.26A 6gtqA-2jjyA:
undetectable		 6gtqA-2jjyA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2la6 RNA-BINDING PROTEIN
FUS

(Homo sapiens) 		PF00076
(RRM_1) 		4 LEU A  62
THR A  55
THR A  59
GLY A  60
 None
 1.22A 6gtqA-2la6A:
undetectable		 6gtqA-2la6A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mvf UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF01201
(Ribosomal_S8e) 		4 LEU A 215
THR A 219
THR A 246
GLY A 218
 None
 1.22A 6gtqA-2mvfA:
undetectable		 6gtqA-2mvfA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471

(Haemophilus
influenzae) 		PF01032
(FecCD) 		4 LEU A 157
THR A 131
THR A 100
GLY A 102
 None
 1.27A 6gtqA-2nq2A:
undetectable		 6gtqA-2nq2A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ood BLR3880 PROTEIN

(Bradyrhizobium
diazoefficiens) 		PF01979
(Amidohydro_1) 		4 LEU A 127
THR A 132
THR A 456
GLY A 131
 None
 1.18A 6gtqA-2oodA:
undetectable		 6gtqA-2oodA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfe ALKALINE SERINE
PROTEASE

(Thermobifida
fusca) 		PF00089
(Trypsin) 		4 LEU A 120
THR A 120
THR A 244
GLY A 245
 None
 1.15A 6gtqA-2pfeA:
undetectable		 6gtqA-2pfeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prx THIOESTERASE
SUPERFAMILY PROTEIN

(Shewanella
loihica) 		PF03061
(4HBT) 		4 LEU A  30
CYH A  67
THR A  70
GLY A  71
 None
 1.28A 6gtqA-2prxA:
undetectable		 6gtqA-2prxA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ptf UNCHARACTERIZED
PROTEIN MTH_863

(Methanothermobacter
thermautotrophicus) 		PF04289
(DUF447) 		4 LEU A  55
THR A  63
CYH A  56
THR A  61
 None
 1.21A 6gtqA-2ptfA:
undetectable		 6gtqA-2ptfA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pxj JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 3A

(Homo sapiens) 		PF02373
(JmjC)
PF02375
(JmjN) 		4 LEU A 125
THR A 126
THR A  83
GLY A  77
 None
 1.28A 6gtqA-2pxjA:
undetectable		 6gtqA-2pxjA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qj8 MLR6093 PROTEIN

(Mesorhizobium
japonicum) 		PF04952
(AstE_AspA) 		4 LEU A 193
THR A 192
THR A 186
GLY A 188
 None
 1.24A 6gtqA-2qj8A:
undetectable		 6gtqA-2qj8A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT

(Pseudomonas
putida) 		PF00355
(Rieske) 		4 THR A  40
CYH A  73
THR A  74
GLY A  75
 None
 1.24A 6gtqA-2qpzA:
undetectable		 6gtqA-2qpzA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 401
CYH A 402
THR A 404
GLY A 406
 None
 0.85A 6gtqA-2v6oA:
undetectable		 6gtqA-2v6oA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 LEU A 537
THR A 548
THR A 471
GLY A 480
 None
 1.24A 6gtqA-2v6oA:
undetectable		 6gtqA-2v6oA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhl N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Bacillus
subtilis) 		PF01979
(Amidohydro_1) 		4 LEU A  87
THR A  92
THR A 380
GLY A  91
 None
 1.19A 6gtqA-2vhlA:
undetectable		 6gtqA-2vhlA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wds HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE

(Streptomyces
coelicolor) 		PF01648
(ACPS) 		4 LEU A  70
THR A  91
THR A  89
GLY A  90
 None
 1.12A 6gtqA-2wdsA:
undetectable		 6gtqA-2wdsA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zws NEUTRAL CERAMIDASE

(Pseudomonas
aeruginosa) 		PF04734
(Ceramidase_alk)
PF17048
(Ceramidse_alk_C) 		4 LEU A 466
THR A 389
THR A 323
GLY A 381
 None
 1.16A 6gtqA-2zwsA:
undetectable		 6gtqA-2zwsA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agr NUCLEOSIDE
TRIPHOSPHATE
HYDROLASE

(Neospora
caninum) 		PF01150
(GDA1_CD39) 		4 LEU A 161
CYH A 162
THR A 164
GLY A  47
 None
 1.23A 6gtqA-3agrA:
undetectable		 6gtqA-3agrA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3byd BETA-LACTAMASE OXY-1

(Klebsiella
oxytoca) 		PF13354
(Beta-lactamase2) 		4 LEU A 172
CYH A  72
THR A  74
GLY A  75
 None
 1.29A 6gtqA-3bydA:
undetectable		 6gtqA-3bydA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0b CONSERVED ARCHAEAL
PROTEIN Q6M145

(Methanococcus
maripaludis) 		PF01968
(Hydantoinase_A) 		4 LEU A 170
THR A 169
THR A 138
GLY A 135
 None
 0.84A 6gtqA-3c0bA:
undetectable		 6gtqA-3c0bA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnc FIBER PROTEIN

(Human
mastadenovirus
B) 		PF00541
(Adeno_knob) 		4 LEU A 213
THR A 210
THR A 338
GLY A 205
 None
 1.19A 6gtqA-3cncA:
undetectable		 6gtqA-3cncA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxl N-CHIMERIN

(Homo sapiens) 		PF00017
(SH2)
PF00130
(C1_1)
PF00620
(RhoGAP) 		4 LEU A 229
THR A 118
THR A 123
GLY A 120
 None
 1.07A 6gtqA-3cxlA:
undetectable		 6gtqA-3cxlA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e48 PUTATIVE
NUCLEOSIDE-DIPHOSPHA
TE-SUGAR EPIMERASE

(Staphylococcus
aureus) 		PF13460
(NAD_binding_10) 		4 LEU A  51
THR A   6
THR A   9
GLY A   7
 None
 1.16A 6gtqA-3e48A:
undetectable		 6gtqA-3e48A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdn R-OXYNITRILE LYASE
ISOENZYME 1

(Prunus dulcis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 THR A 259
CYH A 464
THR A 489
GLY A 487
 None
None
None
FAD  A 522 (-3.6A)
 1.18A 6gtqA-3gdnA:
1.8		 6gtqA-3gdnA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gri DIHYDROOROTASE

(Staphylococcus
aureus) 		PF01979
(Amidohydro_1) 		4 LEU A 332
THR A 328
THR A 302
GLY A 325
 None
 1.19A 6gtqA-3griA:
0.5		 6gtqA-3griA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iac GLUCURONATE
ISOMERASE

(Salmonella
enterica) 		PF02614
(UxaC) 		4 LEU A  74
THR A  80
THR A  76
GLY A  77
 None
 1.16A 6gtqA-3iacA:
undetectable		 6gtqA-3iacA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3imi HIT FAMILY PROTEIN

(Bacillus
anthracis) 		PF01230
(HIT) 		4 LEU A 106
THR A  43
THR A  39
GLY A  41
 None
 0.99A 6gtqA-3imiA:
2.8		 6gtqA-3imiA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3keh GLUCOCEREBROSIDASE

(Homo sapiens) 		PF02055
(Glyco_hydro_30)
PF17189
(Glyco_hydro_30C) 		4 LEU A  66
THR A 471
THR A  63
GLY A  62
 None
 1.13A 6gtqA-3kehA:
undetectable		 6gtqA-3kehA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kqf ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00378
(ECH_1) 		4 LEU A 132
THR A 115
THR A 135
GLY A 112
 None
 1.29A 6gtqA-3kqfA:
undetectable		 6gtqA-3kqfA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l5o UNCHARACTERIZED
PROTEIN FROM DUF364
FAMILY

(Desulfitobacterium
hafniense) 		PF04016
(DUF364)
PF13938
(DUF4213) 		4 LEU A 198
THR A 203
THR A 248
GLY A 219
 None
None
None
EDO  A 307 (-4.1A)
 1.11A 6gtqA-3l5oA:
undetectable		 6gtqA-3l5oA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7x PUTATIVE HIT-LIKE
PROTEIN INVOLVED IN
CELL-CYCLE
REGULATION

(Streptococcus
mutans) 		PF01230
(HIT) 		4 LEU A 102
THR A  39
THR A  35
GLY A  37
 None
 0.97A 6gtqA-3l7xA:
2.2		 6gtqA-3l7xA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m9v FAD-DEPENDENT
OXIDOREDUCTASE

(Actinomadura
kijaniata) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LEU A 104
THR A  66
THR A 109
GLY A 107
 None
None
TYD  A 901 (-4.0A)
None
 1.25A 6gtqA-3m9vA:
undetectable		 6gtqA-3m9vA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nsj PERFORIN-1

(Mus musculus) 		PF00168
(C2)
PF01823
(MACPF) 		4 LEU A 534
THR A 532
THR A 529
GLY A 530
 None
 1.14A 6gtqA-3nsjA:
undetectable		 6gtqA-3nsjA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o1h PERIPLASMIC PROTEIN
TORT

(Vibrio
parahaemolyticus) 		PF00532
(Peripla_BP_1) 		4 LEU B 122
THR B  96
THR B 118
GLY B  95
 None
 1.20A 6gtqA-3o1hB:
undetectable		 6gtqA-3o1hB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgk UREASE SUBUNIT BETA
2

(Helicobacter
mustelae) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 LEU C 194
THR C 172
THR C 170
GLY C 159
 None
None
KCX  C 218 ( 3.4A)
None
 1.15A 6gtqA-3qgkC:
0.0		 6gtqA-3qgkC:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r1w CARBONIC ANHYDRASE

(unidentified) 		PF00132
(Hexapep) 		4 LEU A 112
THR A  95
THR A 169
GLY A 171
 None
 1.28A 6gtqA-3r1wA:
undetectable		 6gtqA-3r1wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rih SHORT CHAIN
DEHYDROGENASE OR
REDUCTASE

(Mycobacteroides
abscessus) 		PF13561
(adh_short_C2) 		4 LEU A  76
THR A  25
THR A  28
GLY A  26
 None
 1.13A 6gtqA-3rihA:
undetectable		 6gtqA-3rihA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr6 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacteroides
abscessus) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 LEU A   3
THR A 176
THR A 141
GLY A 139
 None
 1.21A 6gtqA-3rr6A:
undetectable		 6gtqA-3rr6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos taurus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 LEU C 900
CYH C 901
THR C 903
GLY C 868
 None
 0.97A 6gtqA-3sr6C:
undetectable		 6gtqA-3sr6C:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vue GRANULE-BOUND STARCH
SYNTHASE 1,
CHLOROPLASTIC/AMYLOP
LASTIC

(Oryza sativa) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		4 LEU A 478
THR A 499
CYH A 501
THR A 518
 None
 1.18A 6gtqA-3vueA:
undetectable		 6gtqA-3vueA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wjp HYDROGENASE
EXPRESSION/FORMATION
PROTEIN HYPE

(Thermococcus
kodakarensis) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 LEU A  85
THR A  57
THR A  46
GLY A  44
 None
 1.16A 6gtqA-3wjpA:
undetectable		 6gtqA-3wjpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wst PROTEIN ARGININE
N-METHYLTRANSFERASE
7

(Caenorhabditis
elegans) 		PF13649
(Methyltransf_25) 		4 LEU A 511
THR A  75
THR A 107
GLY A  76
 None
 1.20A 6gtqA-3wstA:
undetectable		 6gtqA-3wstA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2o YMDB
PHOSPHODIESTERASE

(Bacillus
subtilis) 		PF13277
(YmdB) 		4 LEU A 234
THR A 199
THR A 232
GLY A  14
 None
 1.08A 6gtqA-4b2oA:
undetectable		 6gtqA-4b2oA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bps FKBO

(Streptomyces
hygroscopicus) 		no annotation 4 LEU A 326
THR A  64
THR A  46
GLY A  45
 None
 1.25A 6gtqA-4bpsA:
undetectable		 6gtqA-4bpsA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cnk L-AMINO ACID OXIDASE

(Streptococcus
cristatus) 		PF03486
(HI0933_like) 		4 LEU A 349
THR A 381
THR A 161
GLY A 361
 None
None
None
FAD  A1392 (-3.2A)
 1.26A 6gtqA-4cnkA:
undetectable		 6gtqA-4cnkA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dia 2-PYRONE-4,6-DICARBA
XYLATE HYDROLASE

(Sphingomonas
paucimobilis) 		PF04909
(Amidohydro_2) 		4 THR A 247
CYH A 214
THR A 213
GLY A 246
 None
 1.18A 6gtqA-4diaA:
undetectable		 6gtqA-4diaA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f3n UNCHARACTERIZED ACR,
COG1565 SUPERFAMILY

(Burkholderia
thailandensis) 		PF02636
(Methyltransf_28) 		4 LEU A 345
THR A 102
THR A 351
GLY A 349
 None
 1.21A 6gtqA-4f3nA:
0.0		 6gtqA-4f3nA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 LEU B 876
THR B 871
THR B 693
GLY B 691
 None
 1.17A 6gtqA-4f92B:
undetectable		 6gtqA-4f92B:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j35 PHOSPHOTRIESTERASE,
PUTATIVE

(Deinococcus
radiodurans) 		PF02126
(PTE) 		4 LEU A 231
THR A 237
THR A 239
GLY A 233
 None
 1.22A 6gtqA-4j35A:
undetectable		 6gtqA-4j35A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ls9 DHH FAMILY PROTEIN

(Mycolicibacterium
smegmatis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 LEU A 178
THR A 156
THR A 183
GLY A 181
 None
 1.12A 6gtqA-4ls9A:
undetectable		 6gtqA-4ls9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mgg MUCONATE LACTONIZING
ENZYME

(Labrenzia
aggregata) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 222
THR A 196
THR A 199
GLY A 197
 None
None
None
MG  A 403 (-4.0A)
 1.27A 6gtqA-4mggA:
undetectable		 6gtqA-4mggA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3i P DOMAIN OF VP1

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 LEU A 352
THR A 337
THR A 382
GLY A 381
 None
 1.27A 6gtqA-4p3iA:
undetectable		 6gtqA-4p3iA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3z COPN

(Chlamydia
pneumoniae) 		PF07201
(HrpJ) 		4 LEU A 260
THR A 211
THR A 214
GLY A 212
 None
 1.18A 6gtqA-4p3zA:
undetectable		 6gtqA-4p3zA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfz 5-CARBOXYMETHYL-2-HY
DROXYMUCONATE
DELTA-ISOMERASE

(Mycolicibacterium
smegmatis) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 LEU A  24
THR A 194
THR A 159
GLY A 157
 None
 1.14A 6gtqA-4pfzA:
undetectable		 6gtqA-4pfzA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2b ENDO-1,4-BETA-D-GLUC
ANASE

(Pseudomonas
putida) 		PF01270
(Glyco_hydro_8) 		4 LEU A 156
THR A 176
THR A 225
GLY A 175
 None
 1.24A 6gtqA-4q2bA:
undetectable		 6gtqA-4q2bA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02153
(PDH) 		4 LEU A 162
THR A  96
THR A 149
GLY A 122
 None
 1.12A 6gtqA-4wjiA:
undetectable		 6gtqA-4wjiA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1t PERFORIN-1

(Mus musculus) 		PF00168
(C2) 		4 LEU A 534
THR A 532
THR A 529
GLY A 530
 None
 1.12A 6gtqA-4y1tA:
undetectable		 6gtqA-4y1tA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5avp L-RIBOSE ISOMERASE

(Geodermatophilus
obscurus) 		no annotation 4 LEU A  73
CYH A  95
THR A 211
GLY A  93
 None
 1.26A 6gtqA-5avpA:
undetectable		 6gtqA-5avpA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cio PYRROLOQUINOLINE
QUINONE BIOSYNTHESIS
PROTEIN PQQF

(Serratia sp.
FS14) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 LEU A 391
THR A 235
THR A 407
GLY A 409
 None
 0.98A 6gtqA-5cioA:
undetectable		 6gtqA-5cioA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5n MONOOXYGENASE

(Micromonospora
sp. TP-A0468) 		PF05368
(NmrA) 		4 LEU A  35
THR A  11
THR A  14
GLY A  12
 None
None
NAD  A 301 (-3.7A)
NAD  A 301 (-3.4A)
 1.21A 6gtqA-5f5nA:
undetectable		 6gtqA-5f5nA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hh3 OXYA PROTEIN

(Actinoplanes
teichomyceticus) 		PF00067
(p450) 		4 LEU A 153
CYH A 150
THR A 146
GLY A 233
 None
None
None
HEM  A 401 (-3.4A)
 1.22A 6gtqA-5hh3A:
undetectable		 6gtqA-5hh3A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Homo sapiens;
Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 LEU A 626
THR A 634
THR A 630
GLY A 405
 None
 1.27A 6gtqA-5i4eA:
undetectable		 6gtqA-5i4eA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1s OXIDOREDUCTASE,
ZINC-BINDING
DEHYDROGENASE FAMILY

(Myxococcus
xanthus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 THR A 292
CYH A 149
THR A 150
GLY A 152
 None
ZN  A 402 (-2.3A)
None
None
 1.26A 6gtqA-5k1sA:
undetectable		 6gtqA-5k1sA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k95 GTP CYCLOHYDROLASE
FOLE2

(Neisseria
gonorrhoeae) 		PF02649
(GCHY-1) 		4 LEU A  51
THR A  58
THR A  48
GLY A  22
 None
 1.20A 6gtqA-5k95A:
0.9		 6gtqA-5k95A:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzy GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT A

(Myxococcus
xanthus) 		PF01144
(CoA_trans) 		4 LEU A  53
THR A 182
THR A  24
GLY A  26
 None
 1.18A 6gtqA-5mzyA:
undetectable		 6gtqA-5mzyA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 4 LEU B 331
THR B 378
THR B 381
GLY B 374
 None
 1.29A 6gtqA-5nd1B:
undetectable		 6gtqA-5nd1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t95 PREPHENATE
DEHYDROGENASE 1

(Glycine max) 		PF02153
(PDH) 		4 LEU A 212
THR A 211
THR A 206
GLY A 208
 None
 1.22A 6gtqA-5t95A:
undetectable		 6gtqA-5t95A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txr 5-AMINOLEVULINATE
SYNTHASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		no annotation 4 LEU B 472
THR B 469
THR B 465
GLY B 467
 None
None
None
FMT  B 603 ( 3.9A)
 0.95A 6gtqA-5txrB:
undetectable		 6gtqA-5txrB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uyt ICE-BINDING PROTEIN

(Flavobacteriaceae
bacterium
3519-10) 		no annotation 4 LEU A 157
THR A 127
THR A 110
GLY A 108
 None
 1.26A 6gtqA-5uytA:
undetectable		 6gtqA-5uytA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5y PROBABLE ATP-BINDING
COMPONENT OF ABC
TRANSPORTER

(Pseudomonas
aeruginosa) 		no annotation 4 LEU B 201
CYH B 204
THR B 206
GLY B 219
 None
 1.22A 6gtqA-5x5yB:
undetectable		 6gtqA-5x5yB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjj MULTI DRUG EFFLUX
TRANSPORTER

(Camelina sativa) 		PF01554
(MatE) 		4 LEU A  91
THR A  90
CYH A  92
GLY A  86
 None
 1.11A 6gtqA-5xjjA:
undetectable		 6gtqA-5xjjA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtc NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
2

(Homo sapiens) 		no annotation 4 LEU i  44
THR i 122
THR i 125
GLY i 127
 None
 1.28A 6gtqA-5xtci:
undetectable		 6gtqA-5xtci:
21.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5xun ACETYLTRANSFERASE

(Klebsiella
pneumoniae) 		PF13673
(Acetyltransf_10) 		4 LEU A  45
THR A  64
THR A  93
GLY A  95
 None
None
None
ACO  A 201 (-4.8A)
 0.30A 6gtqA-5xunA:
24.7		 6gtqA-5xunA:
65.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e4e -

(-) 		no annotation 4 LEU A  85
THR A  39
THR A   1
GLY A  87
 None
 1.28A 6gtqA-6e4eA:
undetectable		 6gtqA-6e4eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8y THREONYLCARBAMOYL-AM
P SYNTHASE

(Pyrococcus
abyssi) 		no annotation 4 LEU A  97
THR A 182
THR A  35
GLY A 198
 None
None
THR  A 401 (-3.0A)
None
 1.23A 6gtqA-6f8yA:
undetectable		 6gtqA-6f8yA:
undetectable