SIMILAR PATTERNS OF AMINO ACIDS FOR 6GQI_A_ACTA604_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0r PHOSDUCIN

(Bos taurus) 		PF02114
(Phosducin) 		4 ILE P 136
GLY P 194
TYR P 192
GLU P 130
 None
 1.10A 6gqiA-1a0rP:
1.2		 6gqiA-1a0rP:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ccw PROTEIN (GLUTAMATE
MUTASE)

(Clostridium
cochlearium) 		PF06368
(Met_asp_mut_E) 		4 ILE B 211
GLY B 202
TYR B 204
GLU B 205
 None
 0.91A 6gqiA-1ccwB:
0.4		 6gqiA-1ccwB:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgp ARISTOLOCHENE
SYNTHASE

(Penicillium
roqueforti) 		no annotation 4 ILE A 190
GLY A 194
TYR A 196
GLU A 192
 None
 0.81A 6gqiA-1dgpA:
undetectable		 6gqiA-1dgpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fps FARNESYL DIPHOSPHATE
SYNTHASE

(Gallus gallus) 		PF00348
(polyprenyl_synt) 		4 ILE A 255
GLY A 250
TYR A 252
GLU A 251
 None
 1.11A 6gqiA-1fpsA:
0.0		 6gqiA-1fpsA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gtk PORPHOBILINOGEN
DEAMINASE

(Escherichia
coli) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		4 PRO A 266
ILE A 271
GLY A 268
GLU A 138
 None
 1.08A 6gqiA-1gtkA:
0.9		 6gqiA-1gtkA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5y TRANSCRIPTIONAL
REGULATOR, BIOTIN
REPRESSOR FAMILY

(Thermotoga
maritima) 		PF02829
(3H)
PF08279
(HTH_11) 		4 PRO A 106
ILE A 111
GLY A 109
TYR A 108
 None
 1.04A 6gqiA-1j5yA:
0.0		 6gqiA-1j5yA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmt SPLICING FACTOR U2AF
35 KDA SUBUNIT
SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens;
Homo sapiens) 		PF00076
(RRM_1)
no annotation 		4 PRO B  95
TRP A 134
ILE B 102
GLY B  98
 None
None
HEZ  B 201 ( 4.7A)
None
 1.14A 6gqiA-1jmtB:
undetectable		 6gqiA-1jmtB:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l3i PRECORRIN-6Y
METHYLTRANSFERASE/PU
TATIVE DECARBOXYLASE

(Methanothermobacter
thermautotrophicus) 		PF13847
(Methyltransf_31) 		4 PRO A  16
ILE A   2
GLY A  46
GLU A  50
 SAH  A 801 (-4.3A)
None
SAH  A 801 (-3.2A)
None
 1.02A 6gqiA-1l3iA:
3.7		 6gqiA-1l3iA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mc8 FLAP ENDONUCLEASE-1

(Pyrococcus
horikoshii) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		4 PRO A 145
ILE A 326
GLY A 143
GLU A 294
 None
 1.06A 6gqiA-1mc8A:
undetectable		 6gqiA-1mc8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oaz THIOREDOXIN 1

(Escherichia
coli) 		PF00085
(Thioredoxin) 		4 PRO A  34
TRP A  31
ILE A  74
GLY A  88
 None
 1.10A 6gqiA-1oazA:
undetectable		 6gqiA-1oazA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obh LEUCYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2)
PF14795
(Leucyl-specific) 		4 PRO A  42
ILE A 105
GLY A  78
GLU A 124
 LMS  A1817 (-4.1A)
None
None
None
 0.93A 6gqiA-1obhA:
undetectable		 6gqiA-1obhA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wch PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 13

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 PRO A2255
ILE A2231
GLY A2261
TYR A2262
 None
 1.11A 6gqiA-1wchA:
undetectable		 6gqiA-1wchA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xb2 ELONGATION FACTOR
TS, MITOCHONDRIAL

(Bos taurus) 		PF00889
(EF_TS) 		4 PRO B 315
ILE B 307
GLY B 310
TYR B 312
 None
 1.11A 6gqiA-1xb2B:
undetectable		 6gqiA-1xb2B:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xe0 NUCLEOPHOSMIN

(Xenopus laevis) 		PF03066
(Nucleoplasmin) 		4 PRO A  99
ILE A 101
GLY A  66
GLU A  65
 None
 1.06A 6gqiA-1xe0A:
undetectable		 6gqiA-1xe0A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb6 (S)-ACETONE-CYANOHYD
RIN LYASE

(Hevea
brasiliensis) 		PF00561
(Abhydrolase_1) 		4 PRO A  60
ILE A  51
TYR A  57
GLU A  56
 None
 1.07A 6gqiA-1yb6A:
2.0		 6gqiA-1yb6A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybe NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Agrobacterium
tumefaciens) 		PF04095
(NAPRTase) 		4 PRO A 317
ILE A 319
GLY A 321
GLU A 323
 None
 1.12A 6gqiA-1ybeA:
undetectable		 6gqiA-1ybeA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5y APOPTOSIS REGULATOR
CED-9

(Caenorhabditis
elegans) 		PF00452
(Bcl-2)
PF02180
(BH4) 		4 TRP A 221
ILE A  80
GLY A  82
GLU A  81
 None
 0.96A 6gqiA-2a5yA:
undetectable		 6gqiA-2a5yA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buc DIPEPTIDYL PEPTIDASE
IV

(Sus scrofa) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 ILE A 594
GLY A 549
TYR A 670
GLU A 602
 None
 1.13A 6gqiA-2bucA:
undetectable		 6gqiA-2bucA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE

(Porphyromonas
gingivalis) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 ILE A 567
GLY A 520
TYR A 643
GLU A 575
 None
 0.95A 6gqiA-2d5lA:
undetectable		 6gqiA-2d5lA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5t ARCHAEAL
TRANSCRIPTIONAL
REGULATOR TRMB

(Thermococcus
litoralis) 		PF11495
(Regulator_TrmB) 		4 ILE X 336
GLY X 291
TYR X 273
GLU X 275
 None
 1.11A 6gqiA-2f5tX:
undetectable		 6gqiA-2f5tX:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fg9 5-NITROIMIDAZOLE
ANTIBIOTIC
RESISTANCE PROTEIN

(Bacteroides
thetaiotaomicron) 		PF12900
(Pyridox_ox_2) 		4 TRP A 139
ILE A  58
GLY A  52
GLU A  54
 None
 1.06A 6gqiA-2fg9A:
undetectable		 6gqiA-2fg9A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 TRP A 246
ILE A 481
GLY A 322
GLU A 321
 None
 1.04A 6gqiA-2gmhA:
7.4		 6gqiA-2gmhA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hh9 THIAMIN
PYROPHOSPHOKINASE

(Candida
albicans) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 PRO A 107
ILE A 132
GLY A 129
GLU A 126
 None
 0.83A 6gqiA-2hh9A:
undetectable		 6gqiA-2hh9A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lol ACYL CARRIER PROTEIN

(Rickettsia
prowazekii) 		PF00550
(PP-binding) 		4 ILE A  50
GLY A  55
TYR A  54
GLU A  51
 None
 1.02A 6gqiA-2lolA:
undetectable		 6gqiA-2lolA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oae DIPEPTIDYL PEPTIDASE
4

(Rattus
norvegicus) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 ILE A 595
GLY A 550
TYR A 671
GLU A 603
 None
 1.06A 6gqiA-2oaeA:
undetectable		 6gqiA-2oaeA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pbg 6-PHOSPHO-BETA-D-GAL
ACTOSIDASE

(Lactococcus
lactis) 		PF00232
(Glyco_hydro_1) 		4 PRO A 175
TRP A  34
TYR A  42
GLU A  39
 None
 1.08A 6gqiA-2pbgA:
undetectable		 6gqiA-2pbgA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pft EXOCYTOSIS PROTEIN

(Mus musculus) 		PF03081
(Exo70) 		4 ILE A 100
GLY A 114
TYR A 112
GLU A 111
 None
 1.08A 6gqiA-2pftA:
undetectable		 6gqiA-2pftA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ps2 PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Aspergillus
oryzae) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PRO A 137
GLY A 164
TYR A 162
GLU A 191
 None
 1.11A 6gqiA-2ps2A:
undetectable		 6gqiA-2ps2A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r66 GLYCOSYL
TRANSFERASE, GROUP 1

(Halothermothrix
orenii) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		4 PRO A 384
TRP A 428
GLY A 435
GLU A 433
 None
 1.09A 6gqiA-2r66A:
undetectable		 6gqiA-2r66A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rsv SERINE/THREONINE-PRO
TEIN KINASE VRK1

(Homo sapiens) 		PF00069
(Pkinase) 		4 PRO A 111
ILE A 168
GLY A 109
TYR A 167
 None
 0.89A 6gqiA-2rsvA:
undetectable		 6gqiA-2rsvA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v5n CATION-INDEPENDENT
MANNOSE-6-PHOSPHATE
RECEPTOR

(Homo sapiens) 		PF00878
(CIMR) 		4 PRO A1597
ILE A1572
GLY A1595
TYR A1606
 None
 1.14A 6gqiA-2v5nA:
undetectable		 6gqiA-2v5nA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vqa SLL1358 PROTEIN

(Synechocystis
sp. PCC 6803) 		PF00190
(Cupin_1) 		4 PRO A 124
TRP A 145
ILE A 231
GLY A 126
 None
 1.12A 6gqiA-2vqaA:
undetectable		 6gqiA-2vqaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9x POLYPHENOL OXIDASE

(Agaricus
bisporus) 		PF00264
(Tyrosinase) 		4 PRO A  64
ILE A  60
GLY A  62
TYR A  82
 None
 1.12A 6gqiA-2y9xA:
undetectable		 6gqiA-2y9xA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywb GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Thermus
thermophilus) 		PF00117
(GATase)
PF00958
(GMP_synt_C) 		4 PRO A 431
ILE A 401
GLY A 445
GLU A 484
 None
 0.97A 6gqiA-2ywbA:
2.2		 6gqiA-2ywbA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bq9 PREDICTED ROSSMANN
FOLD
NUCLEOTIDE-BINDING
DOMAIN-CONTAINING
PROTEIN

(Idiomarina
baltica) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 PRO A 189
ILE A 155
TYR A 160
GLU A 159
 None
None
None
GOL  A 463 ( 4.9A)
 0.97A 6gqiA-3bq9A:
undetectable		 6gqiA-3bq9A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cih PUTATIVE
ALPHA-RHAMNOSIDASE

(Bacteroides
thetaiotaomicron) 		PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		4 PRO A 225
GLY A 222
TYR A 616
GLU A 223
 None
 0.98A 6gqiA-3cihA:
undetectable		 6gqiA-3cihA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE

(Staphylococcus
epidermidis) 		PF01715
(IPPT) 		4 PRO A  63
ILE A  25
GLY A  61
GLU A  60
 None
 1.14A 6gqiA-3d3qA:
undetectable		 6gqiA-3d3qA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2b DNA-DIRECTED DNA
POLYMERASE III ALPHA
CHAIN

(Geobacillus
kaustophilus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 PRO A 984
GLY A 980
TYR A 982
GLU A 981
 None
 1.03A 6gqiA-3f2bA:
undetectable		 6gqiA-3f2bA:
19.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gwf CYCLOHEXANONE
MONOOXYGENASE

(Rhodococcus sp.
HI-31) 		PF00743
(FMO-like) 		5 PRO A 216
TRP A 273
ILE A 310
GLY A 335
TYR A 337
 None
 0.33A 6gqiA-3gwfA:
46.9		 6gqiA-3gwfA:
62.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdg UNCHARACTERIZED
PROTEIN

(Wolinella
succinogenes) 		PF00072
(Response_reg) 		4 PRO A  53
ILE A  74
GLY A  49
GLU A  45
 None
 0.91A 6gqiA-3hdgA:
2.8		 6gqiA-3hdgA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i3v PROBABLE SECRETED
SOLUTE-BINDING
LIPOPROTEIN

(Streptomyces
coelicolor) 		PF01547
(SBP_bac_1) 		4 PRO A 311
ILE A 175
GLY A 298
GLU A 296
 None
 1.04A 6gqiA-3i3vA:
undetectable		 6gqiA-3i3vA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ian CHITINASE

(Lactococcus
lactis) 		PF00704
(Glyco_hydro_18) 		4 PRO A 212
ILE A 166
GLY A 208
TYR A 210
 None
 1.05A 6gqiA-3ianA:
undetectable		 6gqiA-3ianA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl9 GLUTAMYL
AMINOPEPTIDASE

(Streptococcus
pneumoniae) 		PF05343
(Peptidase_M42) 		4 ILE A 282
GLY A 253
TYR A 284
GLU A 331
 None
 1.08A 6gqiA-3kl9A:
2.1		 6gqiA-3kl9A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
putida) 		PF07238
(PilZ)
PF07317
(YcgR) 		4 PRO A  33
ILE A  35
GLY A  83
GLU A  82
 None
 1.05A 6gqiA-3kyfA:
undetectable		 6gqiA-3kyfA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lov PROTOPORPHYRINOGEN
OXIDASE

(Exiguobacterium
sibiricum) 		PF01593
(Amino_oxidase) 		4 PRO A 155
ILE A 147
GLY A 150
TYR A 152
 None
 0.94A 6gqiA-3lovA:
4.8		 6gqiA-3lovA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8y PHOSPHOPENTOMUTASE

(Bacillus cereus) 		PF01676
(Metalloenzyme) 		4 PRO A 219
TRP A  90
ILE A  97
GLY A 221
 None
 1.11A 6gqiA-3m8yA:
undetectable		 6gqiA-3m8yA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n05 NH(3)-DEPENDENT
NAD(+) SYNTHETASE

(Streptomyces
avermitilis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 PRO A 245
ILE A 219
GLY A 250
GLU A 249
 None
 1.03A 6gqiA-3n05A:
2.7		 6gqiA-3n05A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nap CAPSID PROTEIN
CAPSID PROTEIN

(Triatoma virus;
Triatoma virus) 		PF08762
(CRPV_capsid)
PF00073
(Rhv) 		4 PRO C 261
ILE A  43
TYR C 116
GLU C 257
 None
 1.00A 6gqiA-3napC:
undetectable		 6gqiA-3napC:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q5e ATLASTIN-1

(Homo sapiens) 		PF02263
(GBP) 		4 PRO A 380
ILE A 374
GLY A 376
GLU A 373
 None
 1.14A 6gqiA-3q5eA:
undetectable		 6gqiA-3q5eA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rcy MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Roseovarius sp.
TM1035) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PRO A  13
TRP A  23
ILE A 337
GLY A  17
 None
 0.90A 6gqiA-3rcyA:
undetectable		 6gqiA-3rcyA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rks HYDROXYNITRILASE

(Manihot
esculenta) 		PF00561
(Abhydrolase_1) 		4 PRO A  60
ILE A  51
TYR A  57
GLU A  56
 None
 0.80A 6gqiA-3rksA:
undetectable		 6gqiA-3rksA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv6 ISOCHORISMATE
SYNTHASE/ISOCHORISMA
TE-PYRUVATE LYASE
MBTI

(Mycobacterium
tuberculosis) 		PF00425
(Chorismate_bind) 		4 PRO A 366
GLY A 370
TYR A 119
GLU A 372
 RVA  A 454 (-3.9A)
None
None
None
 1.10A 6gqiA-3rv6A:
undetectable		 6gqiA-3rv6A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4w MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Sulfitobacter
sp. NAS-14.1) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PRO A  13
TRP A  23
ILE A 337
GLY A  17
 None
 0.89A 6gqiA-3t4wA:
undetectable		 6gqiA-3t4wA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tnf LIDA

(Legionella
pneumophila) 		no annotation 4 TRP B 510
ILE B 513
TYR B 502
GLU B 508
 None
 1.09A 6gqiA-3tnfB:
undetectable		 6gqiA-3tnfB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ukf UDP-GALACTOPYRANOSE
MUTASE

(Aspergillus
fumigatus) 		PF13450
(NAD_binding_8) 		4 PRO A 307
TRP A 368
ILE A 330
GLY A 311
 None
 0.99A 6gqiA-3ukfA:
11.3		 6gqiA-3ukfA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnd TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Shewanella
frigidimarina) 		PF00290
(Trp_syntA) 		4 PRO A 209
ILE A 194
GLY A 228
GLU A 195
 None
 1.02A 6gqiA-3vndA:
undetectable		 6gqiA-3vndA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab4 XENOBIOTIC REDUCTASE
B

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		4 PRO A 315
ILE A 344
TYR A  42
GLU A  41
 None
 0.97A 6gqiA-4ab4A:
undetectable		 6gqiA-4ab4A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4arc LEUCINE--TRNA LIGASE

(Escherichia
coli) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 PRO A  42
ILE A 105
GLY A  78
GLU A 124
 LEU  A1001 ( 4.9A)
None
None
None
 1.11A 6gqiA-4arcA:
undetectable		 6gqiA-4arcA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bof ARGININE DEIMINASE

(Streptococcus
pyogenes) 		PF02274
(Amidinotransf) 		4 PRO A 200
ILE A 195
GLY A 203
TYR A 202
 None
 1.01A 6gqiA-4bofA:
undetectable		 6gqiA-4bofA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7g BETA-N-ACETYLHEXOSAM
INIDASE

(Streptomyces
coelicolor) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b) 		4 ILE A  10
GLY A 450
TYR A 168
GLU A 453
 None
 1.08A 6gqiA-4c7gA:
undetectable		 6gqiA-4c7gA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvu BETA-MANNOSIDASE

(Trichoderma
harzianum) 		PF00703
(Glyco_hydro_2) 		4 PRO A 833
TRP A 762
ILE A 377
GLY A 319
 None
 1.07A 6gqiA-4cvuA:
undetectable		 6gqiA-4cvuA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkb DEOXYURIDINE
TRIPHOSPHATASE

(Trypanosoma
brucei) 		PF08761
(dUTPase_2) 		4 PRO A 274
ILE A 214
GLY A 272
TYR A 268
 None
 1.11A 6gqiA-4dkbA:
undetectable		 6gqiA-4dkbA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwt THREONINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		4 PRO A 658
GLY A 710
TYR A 666
GLU A 711
 None
 1.14A 6gqiA-4hwtA:
3.1		 6gqiA-4hwtA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ix2 INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Vibrio cholerae) 		PF00478
(IMPDH) 		4 PRO A  45
ILE A 433
GLY A  68
GLU A  66
 None
 1.06A 6gqiA-4ix2A:
undetectable		 6gqiA-4ix2A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3z MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Jannaschia sp.
CCS1) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 PRO A  14
TRP A  24
ILE A 337
GLY A  18
 None
 0.92A 6gqiA-4j3zA:
undetectable		 6gqiA-4j3zA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnv THIOESTER-CONTAINING
PROTEIN I

(Anopheles
gambiae) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		4 PRO A 653
TRP A 633
ILE A 533
GLY A 530
 None
 1.08A 6gqiA-4lnvA:
undetectable		 6gqiA-4lnvA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npa PUTATIVE
UNCHARACTERIZED
PROTEIN

(Vibrio cholerae) 		PF03641
(Lysine_decarbox)
PF11892
(DUF3412)
PF14793
(DUF4478) 		4 PRO A 195
ILE A 161
TYR A 166
GLU A 165
 None
 0.87A 6gqiA-4npaA:
undetectable		 6gqiA-4npaA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nq8 PUTATIVE PERIPLASMIC
SUBSTRATE-BINDING
TRANSPORT PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		4 ILE A  51
GLY A  57
TYR A  59
GLU A  52
 None
 0.91A 6gqiA-4nq8A:
undetectable		 6gqiA-4nq8A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5f TYPE III
PANTOTHENATE KINASE

(Burkholderia
thailandensis) 		PF03309
(Pan_kinase) 		4 PRO A  47
TRP A  72
ILE A  68
GLY A  49
 None
 1.09A 6gqiA-4o5fA:
undetectable		 6gqiA-4o5fA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o96 TYPE III EFFECTOR
PROTEIN KINASE

(Escherichia
coli) 		no annotation 4 ILE A 222
GLY A 216
TYR A 257
GLU A 217
 None
 1.10A 6gqiA-4o96A:
undetectable		 6gqiA-4o96A:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psp ALPHA-FUCOSIDASE
GH29

(Fusarium
graminearum) 		PF01120
(Alpha_L_fucos)
PF16757
(Fucosidase_C) 		4 PRO A 142
ILE A  79
GLY A 146
TYR A 145
 None
 1.12A 6gqiA-4pspA:
undetectable		 6gqiA-4pspA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptf DNA POLYMERASE
EPSILON CATALYTIC
SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		4 PRO A 532
TRP A 841
ILE A 529
GLU A 173
 None
 1.10A 6gqiA-4ptfA:
undetectable		 6gqiA-4ptfA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rnw NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 PRO A  54
ILE A  83
TYR A 155
GLU A 154
 None
 1.04A 6gqiA-4rnwA:
undetectable		 6gqiA-4rnwA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s17 GLUTAMINE SYNTHETASE

(Bifidobacterium
adolescentis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 PRO A 399
ILE A 352
GLY A 308
TYR A 343
 None
 1.13A 6gqiA-4s17A:
undetectable		 6gqiA-4s17A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tmc OLD YELLOW ENZYME

(Kluyveromyces
marxianus) 		PF00724
(Oxidored_FMN) 		4 PRO A  48
TRP A  97
TYR A  57
GLU A  54
 None
 1.06A 6gqiA-4tmcA:
undetectable		 6gqiA-4tmcA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w5z CHITINASE 60

(Moritella
marina) 		PF00704
(Glyco_hydro_18) 		4 PRO A 203
ILE A 157
GLY A 199
TYR A 201
 None
 1.06A 6gqiA-4w5zA:
undetectable		 6gqiA-4w5zA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wn9 NITROGENASE
MOLYBDENUM-IRON
PROTEIN ALPHA CHAIN

(Clostridium
pasteurianum) 		PF00148
(Oxidored_nitro) 		4 PRO A  65
ILE A 218
GLY A 242
GLU A 215
 None
ICS  A 602 ( 4.9A)
None
None
 1.14A 6gqiA-4wn9A:
2.2		 6gqiA-4wn9A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ync NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 PRO A 354
ILE A 383
TYR A  56
GLU A  55
 None
 1.02A 6gqiA-4yncA:
undetectable		 6gqiA-4yncA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zef AMINO ACID ABC
TRANSPORTER AMINO
ACID-BINDING/PERMEAS
E

(Enterococcus
faecalis) 		PF00497
(SBP_bac_3) 		4 ILE A 475
GLY A 470
TYR A 472
GLU A 471
 None
 1.11A 6gqiA-4zefA:
undetectable		 6gqiA-4zefA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zu9 ELONGATION FACTOR
SELB

(Aquifex
aeolicus) 		PF00009
(GTP_EFTU)
PF09107
(SelB-wing_3) 		4 PRO A 501
ILE A 495
GLY A 499
GLU A 498
 None
 1.13A 6gqiA-4zu9A:
undetectable		 6gqiA-4zu9A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah5 LEUCINE--TRNA LIGASE

(Agrobacterium
tumefaciens) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1)
PF13603
(tRNA-synt_1_2) 		4 PRO A  40
ILE A 103
GLY A  76
GLU A 122
 LSS  A1818 (-4.3A)
None
None
None
 1.01A 6gqiA-5ah5A:
undetectable		 6gqiA-5ah5A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2

(Homo sapiens) 		PF01551
(Peptidase_M23) 		4 PRO A  51
ILE A  96
GLY A  99
GLU A 100
 None
 1.06A 6gqiA-5b0hA:
undetectable		 6gqiA-5b0hA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzc VRC01 FAB HEAVY
CHAIN

(Homo sapiens) 		no annotation 4 PRO H 108
ILE H  20
GLY H 106
TYR H  90
 None
 1.12A 6gqiA-5kzcH:
undetectable		 6gqiA-5kzcH:
18.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5m10 CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE

(Thermocrispum
municipale) 		PF07992
(Pyr_redox_2) 		5 PRO A 216
TRP A 273
ILE A 310
GLY A 335
TYR A 337
 GOL  A 607 ( 3.9A)
None
GOL  A 607 (-4.7A)
GOL  A 607 (-3.8A)
GOL  A 607 (-4.4A)
 0.24A 6gqiA-5m10A:
55.9		 6gqiA-5m10A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5min QUINOPROTEIN GLUCOSE
DEHYDROGENASE B

(Acinetobacter
calcoaceticus) 		no annotation 4 PRO A 414
TRP A  34
ILE A 411
TYR A 420
 None
 1.13A 6gqiA-5minA:
undetectable		 6gqiA-5minA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpt CITRININ POLYKETIDE
SYNTHASE

(Monascus
purpureus) 		PF08242
(Methyltransf_12) 		4 ILE A1882
GLY A1872
TYR A1871
GLU A1875
 None
 1.08A 6gqiA-5mptA:
undetectable		 6gqiA-5mptA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tdx ANCESTRAL
HYDROXYNITRILE LYASE
1

(synthetic
construct) 		no annotation 4 PRO A  60
ILE A  51
TYR A  57
GLU A  56
 None
 0.82A 6gqiA-5tdxA:
2.0		 6gqiA-5tdxA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhu MYCINAMICIN IV
HYDROXYLASE/EPOXIDAS
E

(Micromonospora
griseorubida) 		PF00067
(p450) 		4 PRO A  37
GLY A  40
TYR A  39
GLU A  71
 None
 1.09A 6gqiA-5uhuA:
undetectable		 6gqiA-5uhuA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj6 GLYCOSYL HYDROLASES
FAMILY 2, SUGAR
BINDING DOMAIN
PROTEIN

(Bacteroides
uniformis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF11721
(Malectin)
PF16355
(DUF4982) 		4 PRO A 518
GLY A 310
TYR A 566
GLU A 312
 None
 1.05A 6gqiA-5uj6A:
undetectable		 6gqiA-5uj6A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uze INOSINE-5'-MONOPHOSP
HATE
DEHYDROGENASE,INOSIN
E-5'-MONOPHOSPHATE
DEHYDROGENASE

(Clostridium
perfringens) 		PF00478
(IMPDH) 		4 PRO A  43
ILE A 427
GLY A  66
GLU A  64
 None
 1.00A 6gqiA-5uzeA:
undetectable		 6gqiA-5uzeA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4c THIOREDOXIN
REDUCTASE

(Cryptococcus
neoformans) 		no annotation 4 PRO A  56
ILE A 109
GLY A 106
GLU A 103
 None
 1.12A 6gqiA-5w4cA:
10.6		 6gqiA-5w4cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xl2 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 TRP A  80
ILE A  62
GLY A  57
GLU A  85
 None
 0.91A 6gqiA-5xl2A:
undetectable		 6gqiA-5xl2A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xl6 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		4 TRP A  80
ILE A  62
GLY A  57
GLU A  85
 None
 0.92A 6gqiA-5xl6A:
undetectable		 6gqiA-5xl6A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ywz SUN
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		no annotation 4 PRO A 826
ILE A 792
TYR A 903
GLU A 823
 None
 0.69A 6gqiA-5ywzA:
2.5		 6gqiA-5ywzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anz UNCHARACTERIZED
PROTEIN

(Neisseria
gonorrhoeae) 		no annotation 4 ILE A 103
GLY A  47
TYR A  67
GLU A  69
 None
 1.07A 6gqiA-6anzA:
undetectable		 6gqiA-6anzA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3r PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		no annotation 4 PRO A2346
ILE A2315
GLY A2311
GLU A2307
 None
 1.08A 6gqiA-6b3rA:
undetectable		 6gqiA-6b3rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd6 PHOTOLYASE PHRB

(Agrobacterium
tumefaciens) 		no annotation 4 TRP A 142
GLY A 316
TYR A 313
GLU A 312
 None
 1.11A 6gqiA-6dd6A:
undetectable		 6gqiA-6dd6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eot DIPEPTIDYL PEPTIDASE
8

(Homo sapiens) 		no annotation 4 TRP A 754
ILE A 867
GLY A 830
TYR A 860
 None
 1.10A 6gqiA-6eotA:
undetectable		 6gqiA-6eotA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2

(Mus musculus) 		no annotation 4 PRO A  57
ILE A  53
GLY A  55
GLU A 385
 None
 1.13A 6gqiA-6fv5A:
undetectable		 6gqiA-6fv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
9, MITOCHONDRIAL

(Mus musculus) 		no annotation 4 PRO P 114
ILE P 165
GLY P 152
GLU P 153
 None
 1.10A 6gqiA-6g2jP:
undetectable		 6gqiA-6g2jP:
undetectable