SIMILAR PATTERNS OF AMINO ACIDS FOR 6GP2_A_DAHA126
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a7j | PHOSPHORIBULOKINASE (Rhodobactersphaeroides) |
PF00485(PRK) | 5 | PHE A 84GLY A 88ILE A 7PHE A 44ILE A 39 | None | 0.87A | 6gp2A-1a7jA:undetectable | 6gp2A-1a7jA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ecx | AMINOTRANSFERASE (Thermotogamaritima) |
PF00266(Aminotran_5) | 5 | PHE A 299GLY A 304ILE A 349ILE A 369ILE A 372 | None | 1.06A | 6gp2A-1ecxA:undetectable | 6gp2A-1ecxA:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eww | ANTIFREEZE PROTEIN (Choristoneurafumiferana) |
PF05264(CfAFP) | 5 | PHE A 87SER A 52GLY A 54ILE A 82ILE A 64 | None | 0.99A | 6gp2A-1ewwA:undetectable | 6gp2A-1ewwA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8r | L-AMINO ACID OXIDASE (Calloselasmarhodostoma) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 0.99A | 6gp2A-1f8rA:undetectable | 6gp2A-1f8rA:10.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g0d | PROTEIN-GLUTAMINEGAMMA-GLUTAMYLTRANSFERASE (Pagrus major) |
PF00868(Transglut_N)PF00927(Transglut_C)PF01841(Transglut_core) | 5 | PHE A 189LEU A 192ASP A 205GLY A 63ILE A 105 | None | 0.95A | 6gp2A-1g0dA:undetectable | 6gp2A-1g0dA:7.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g71 | DNA PRIMASE (Pyrococcusfuriosus) |
PF01896(DNA_primase_S) | 5 | SER A 73GLY A 38PHE A 39ILE A 24ILE A 28 | None | 1.05A | 6gp2A-1g71A:undetectable | 6gp2A-1g71A:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8x | MYOSIN II HEAVYCHAIN FUSED TOALPHA-ACTININ 3 (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF00435(Spectrin)PF02736(Myosin_N) | 5 | LEU A 529ASP A 530GLY A 519ILE A 517PHE A 466 | None | 0.92A | 6gp2A-1g8xA:undetectable | 6gp2A-1g8xA:6.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jx2 | MYOSIN-2 HEAVYCHAIN,DYNAMIN-A (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | LEU A 540ASP A 541GLY A 530ILE A 528PHE A 477 | None | 0.86A | 6gp2A-1jx2A:undetectable | 6gp2A-1jx2A:5.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77ILE A 118PHE A 176ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNone | 0.63A | 6gp2A-1kgpA:41.5 | 6gp2A-1kgpA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ASP A 77SER A 114ILE A 118ILE A 195ILE A 198 | NoneNoneNone MN A1001 (-2.7A)NoneNoneNoneNone | 0.62A | 6gp2A-1kgpA:41.5 | 6gp2A-1kgpA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kgp | RIBONUCLEOTIDEREDUCTASE PROTEINR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ILE A 118PHE A 119PHE A 176ILE A 195ILE A 198 | None | 0.63A | 6gp2A-1kgpA:41.5 | 6gp2A-1kgpA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kru | GALACTOSIDEO-ACETYLTRANSFERASE (Escherichiacoli) |
PF00132(Hexapep)PF12464(Mac)PF14602(Hexapep_2) | 5 | LEU A 88ILE A 51PHE A 36ILE A 78ILE A 76 | None | 1.06A | 6gp2A-1kruA:undetectable | 6gp2A-1kruA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogq | POLYGALACTURONASEINHIBITING PROTEIN (Phaseolusvulgaris) |
PF08263(LRRNT_2) | 6 | LEU A 141GLY A 170PHE A 194PHE A 156ILE A 154ILE A 145 | None | 1.13A | 6gp2A-1ogqA:undetectable | 6gp2A-1ogqA:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pc3 | PHOSPHATE-BINDINGPROTEIN 1 (Mycobacteriumtuberculosis) |
PF12849(PBP_like_2) | 6 | PHE A 312LEU A 309THR A 308ILE A 58PHE A 49ILE A 79 | None | 1.46A | 6gp2A-1pc3A:undetectable | 6gp2A-1pc3A:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 6 | THR A 81SER A 121ILE A 125PHE A 212ILE A 231ILE A 234 | None | 0.82A | 6gp2A-1pm2A:29.1 | 6gp2A-1pm2A:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qqj | FUMARYLACETOACETATEHYDROLASE (Mus musculus) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 230GLY A 349ILE A 351PHE A 405ILE A 297 | None CA A 420 ( 4.5A)NoneNoneNone | 1.02A | 6gp2A-1qqjA:undetectable | 6gp2A-1qqjA:11.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 60LEU A 63THR A 64ASP A 67ILE A 108PHE A 109PHE A 166ILE A 185ILE A 188 | NoneNoneNone FE A 400 (-3.0A)NoneNoneNoneNoneNone | 0.58A | 6gp2A-1r2fA:42.0 | 6gp2A-1r2fA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r2f | PROTEIN(RIBONUCLEOTIDEREDUCTASE R2) (Salmonellaenterica) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 60LEU A 63THR A 64ASP A 67SER A 104ILE A 108PHE A 109ILE A 185ILE A 188 | NoneNoneNone FE A 400 (-3.0A)NoneNoneNoneNoneNone | 0.59A | 6gp2A-1r2fA:42.0 | 6gp2A-1r2fA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1suh | EPITHELIAL CADHERIN (Mus musculus) |
PF00028(Cadherin) | 5 | LEU A 21GLY A 58ILE A 53ILE A 96ILE A 7 | None | 1.04A | 6gp2A-1suhA:undetectable | 6gp2A-1suhA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdk | L-AMINO ACID OXIDASE (Gloydius halys) |
PF01593(Amino_oxidase) | 5 | PHE A 381LEU A 384ASP A 385ILE A 327ILE A 392 | None | 0.90A | 6gp2A-1tdkA:undetectable | 6gp2A-1tdkA:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 6 | PHE A 65LEU A 68THR A 66ILE A 113PHE A 114ILE A 190 | None | 1.49A | 6gp2A-1uzrA:40.5 | 6gp2A-1uzrA:26.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 65LEU A 68THR A 69ASP A 72SER A 109ILE A 113ILE A 190ILE A 193 | NoneNoneNone FE A1292 (-2.5A)NoneNoneNoneNone | 0.53A | 6gp2A-1uzrA:40.5 | 6gp2A-1uzrA:26.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 65LEU A 68THR A 69ASP A 72SER A 109ILE A 113PHE A 171ILE A 193 | NoneNoneNone FE A1292 (-2.5A)NoneNoneNoneNone | 0.63A | 6gp2A-1uzrA:40.5 | 6gp2A-1uzrA:26.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 65LEU A 68THR A 69SER A 109ILE A 113PHE A 114ILE A 190ILE A 193 | None | 0.44A | 6gp2A-1uzrA:40.5 | 6gp2A-1uzrA:26.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uzr | RIBONUCLEOTIDEREDUCTASE R2-2 SMALLSUBUNIT (Mycobacteriumtuberculosis) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 65LEU A 68THR A 69SER A 109ILE A 113PHE A 114PHE A 171ILE A 193 | None | 0.56A | 6gp2A-1uzrA:40.5 | 6gp2A-1uzrA:26.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v33 | DNA PRIMASE SMALLSUBUNIT (Pyrococcushorikoshii) |
PF01896(DNA_primase_S) | 5 | SER A 73GLY A 38PHE A 39ILE A 24ILE A 28 | None | 1.06A | 6gp2A-1v33A:undetectable | 6gp2A-1v33A:10.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfi | UNKNOWN PROTEIN (Arabidopsisthaliana) |
PF01937(DUF89) | 5 | LEU A 237GLY A 229ILE A 159ILE A 316ILE A 217 | None | 0.97A | 6gp2A-1xfiA:undetectable | 6gp2A-1xfiA:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6o | ISHP608 TRANSPOSASE (Helicobacterpylori) |
PF01797(Y1_Tnp) | 5 | PHE A 80GLY A 76ILE A 71PHE A 75ILE A 21 | None | 1.03A | 6gp2A-2a6oA:undetectable | 6gp2A-2a6oA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bm3 | SCAFFOLDING DOCKERINBINDING PROTEIN A (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 73GLY A 69ILE A 116PHE A 36ILE A 30 | None | 0.93A | 6gp2A-2bm3A:undetectable | 6gp2A-2bm3A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g28 | PYRUVATEDEHYDROGENASE E1COMPONENT (Escherichiacoli) |
PF00456(Transketolase_N) | 5 | PHE A 532LEU A 531GLY A 562ILE A 537ILE A 519 | None | 0.97A | 6gp2A-2g28A:undetectable | 6gp2A-2g28A:9.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gb4 | THIOPURINES-METHYLTRANSFERASE (Mus musculus) |
PF05724(TPMT) | 5 | PHE A 61GLY A 139ILE A 138ILE A 130ILE A 164 | NoneNoneNoneSAH A 300 (-4.5A)None | 1.08A | 6gp2A-2gb4A:undetectable | 6gp2A-2gb4A:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwm | 65 KDA VIRULENCEPROTEIN (Salmonellaenterica) |
PF03496(ADPrib_exo_Tox) | 5 | LEU A 427THR A 426GLY A 405ILE A 409PHE A 443 | None | 0.89A | 6gp2A-2gwmA:undetectable | 6gp2A-2gwmA:15.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ifa | HYPOTHETICAL PROTEINSMU.260 (Streptococcusmutans) |
PF00881(Nitroreductase) | 5 | PHE A 176GLY A 144ILE A 143ILE A 32ILE A 134 | None | 0.99A | 6gp2A-2ifaA:undetectable | 6gp2A-2ifaA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jdx | PROTEIN(L-ARGININE:GLYCINEAMIDINOTRANSFERASE) (Homo sapiens) |
no annotation | 5 | PHE A 383GLY A 387ILE A 388ILE A 311ILE A 315 | None | 1.03A | 6gp2A-2jdxA:undetectable | 6gp2A-2jdxA:12.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mjp | PYROPHOSPHATASE (Methanocaldococcusjannaschii) |
PF01725(Ham1p_like) | 5 | LEU A 28ILE A 21PHE A 185ILE A 70ILE A 11 | None | 0.85A | 6gp2A-2mjpA:undetectable | 6gp2A-2mjpA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rcc | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillushalodurans) |
PF00268(Ribonuc_red_sm) | 5 | LEU A 84SER A 124PHE A 193ILE A 212ILE A 215 | None | 0.85A | 6gp2A-2rccA:27.4 | 6gp2A-2rccA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vdw | VACCINIA VIRUSCAPPING ENZYME D1SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL) | 6 | LEU A 700THR A 701PHE A 780PHE A 659ILE A 654ILE A 597 | None | 1.15A | 6gp2A-2vdwA:undetectable | 6gp2A-2vdwA:13.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y9e | MYOSIN-2 (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF02736(Myosin_N) | 5 | LEU X 529ASP X 530GLY X 519ILE X 517PHE X 466 | None | 0.99A | 6gp2A-2y9eX:undetectable | 6gp2A-2y9eX:7.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhe | SEC-ALKYL SULFATASE (Pseudomonas sp.DSM 6611) |
PF00753(Lactamase_B)PF14863(Alkyl_sulf_dimr)PF14864(Alkyl_sulf_C) | 5 | LEU A 261THR A 260GLY A 190ILE A 192PHE A 210 | None | 0.91A | 6gp2A-2yheA:undetectable | 6gp2A-2yheA:8.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0r | UBIQUITINTHIOESTERASE OTU1 (Saccharomycescerevisiae) |
PF02338(OTU) | 5 | LEU A 138GLY A 182ILE A 192PHE A 130ILE A 129 | None | 0.90A | 6gp2A-3c0rA:undetectable | 6gp2A-3c0rA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e74 | ALLANTOINASE (Escherichiacoli) |
PF01979(Amidohydro_1) | 5 | PHE A 388GLY A 10ILE A 7ILE A 30ILE A 33 | None | 1.05A | 6gp2A-3e74A:undetectable | 6gp2A-3e74A:10.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9k | KYNURENINASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU A 368THR A 365GLY A 400ILE A 405ILE A 390 | None | 0.96A | 6gp2A-3e9kA:undetectable | 6gp2A-3e9kA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ege | PUTATIVEMETHYLTRANSFERASEFROM ANTIBIOTICBIOSYNTHESIS PATHWAY (Trichormusvariabilis) |
PF08241(Methyltransf_11) | 5 | LEU A 101SER A 208GLY A 206ILE A 207PHE A 130 | None | 1.04A | 6gp2A-3egeA:undetectable | 6gp2A-3egeA:16.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5o | TRANSCRIPTIONALREGULATOR GNTR (Chromobacteriumviolaceum) |
PF13377(Peripla_BP_3) | 5 | LEU A 86GLY A 306ILE A 92ILE A 105ILE A 77 | None | 1.04A | 6gp2A-3h5oA:undetectable | 6gp2A-3h5oA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | PHE A 174LEU A 171GLY A 207ILE A 208ILE A 247 | None | 0.95A | 6gp2A-3i04A:undetectable | 6gp2A-3i04A:7.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzp | PUTATIVE DIGUANYLATECYCLASE/PHOSPHODIESTERASE (Listeriamonocytogenes) |
PF00563(EAL) | 5 | LEU A 96ILE A 137PHE A 63ILE A 77ILE A 103 | None | 0.92A | 6gp2A-3kzpA:undetectable | 6gp2A-3kzpA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604THR A 471GLY A 599ILE A 603ILE A 457 | None | 0.88A | 6gp2A-3lk6A:undetectable | 6gp2A-3lk6A:8.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 5 | LEU A 73ASP A 77PHE A 176ILE A 195ILE A 198 | NoneMN3 A1001 (-2.2A)NoneNoneNone | 0.85A | 6gp2A-3mjoA:40.6 | 6gp2A-3mjoA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 8 | PHE A 70LEU A 73THR A 74ILE A 118PHE A 119PHE A 176ILE A 195ILE A 198 | None | 0.59A | 6gp2A-3mjoA:40.6 | 6gp2A-3mjoA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjo | RIBONUCLEOTIDEREDUCTASE SUBUNITR2F (Corynebacteriumammoniagenes) |
PF00268(Ribonuc_red_sm) | 7 | PHE A 70LEU A 73THR A 74SER A 114ILE A 118ILE A 195ILE A 198 | None | 0.54A | 6gp2A-3mjoA:40.6 | 6gp2A-3mjoA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n00 | REV-ERBA-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 545THR A 541ILE A 299PHE A 300ILE A 457 | None | 1.02A | 6gp2A-3n00A:undetectable | 6gp2A-3n00A:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 7 | PHE B 60LEU B 63ASP B 67ILE B 108PHE B 166ILE B 185ILE B 188 | NoneNone MN B 320 (-2.8A)NoneNoneNoneNone | 0.66A | 6gp2A-3n3bB:41.1 | 6gp2A-3n3bB:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 7 | PHE B 60LEU B 63ASP B 67SER B 104ILE B 108ILE B 185ILE B 188 | NoneNone MN B 320 (-2.8A)NoneNoneNoneNone | 0.73A | 6gp2A-3n3bB:41.1 | 6gp2A-3n3bB:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3b | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2SUBUNIT BETA (Escherichiacoli) |
no annotation | 8 | PHE B 60LEU B 63THR B 64ILE B 108PHE B 109PHE B 166ILE B 185ILE B 188 | None | 0.56A | 6gp2A-3n3bB:41.1 | 6gp2A-3n3bB:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3njx | RHAMNOGALACTURONASEB (Aspergillusaculeatus) |
PF09284(RhgB_N)PF14683(CBM-like)PF14686(fn3_3) | 5 | LEU A 506GLY A 420ILE A 419ILE A 481ILE A 403 | None | 1.07A | 6gp2A-3njxA:undetectable | 6gp2A-3njxA:9.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojl | CAP5O (Staphylococcusaureus) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | LEU A 221THR A 222GLY A 251ILE A 247ILE A 236 | None | 0.96A | 6gp2A-3ojlA:undetectable | 6gp2A-3ojlA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sun | DNA POLYMERASE (Escherichiavirus RB69) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | PHE A 841GLY A 807ILE A 846ILE A 858ILE A 815 | None | 1.04A | 6gp2A-3sunA:undetectable | 6gp2A-3sunA:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsw | TIGHT JUNCTIONPROTEIN ZO-1 (Homo sapiens) |
PF00595(PDZ)PF00625(Guanylate_kin)PF07653(SH3_2) | 5 | LEU A 549THR A 548ASP A 547GLY A 440ILE A 445 | None | 1.06A | 6gp2A-3tswA:undetectable | 6gp2A-3tswA:10.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wuy | NITRILASE (Synechocystissp. PCC 6803) |
PF00795(CN_hydrolase) | 5 | LEU A 106GLY A 127PHE A 51ILE A 49ILE A 38 | None | 1.05A | 6gp2A-3wuyA:undetectable | 6gp2A-3wuyA:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2p | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C) | 6 | PHE A 358LEU A 354GLY A 361PHE A 369ILE A 368ILE A 341 | None | 1.41A | 6gp2A-4a2pA:2.1 | 6gp2A-4a2pA:9.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2q | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 6 | PHE A 358LEU A 354GLY A 361PHE A 369ILE A 368ILE A 341 | None | 1.33A | 6gp2A-4a2qA:undetectable | 6gp2A-4a2qA:6.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2w | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 6 | PHE A 358LEU A 354GLY A 361PHE A 369ILE A 368ILE A 341 | None | 1.26A | 6gp2A-4a2wA:undetectable | 6gp2A-4a2wA:5.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 6 | LEU A 58THR A 59ASP A 62ILE A 103PHE A 169ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNone | 0.77A | 6gp2A-4bmrA:37.8 | 6gp2A-4bmrA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 7 | LEU A 58THR A 59ASP A 62SER A 99ILE A 103ILE A 188ILE A 191 | NoneNoneFE2 A1323 (-2.4A)NoneNoneNoneNone | 0.75A | 6gp2A-4bmrA:37.8 | 6gp2A-4bmrA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 6 | LEU A 58THR A 59ILE A 103PHE A 104ILE A 188ILE A 191 | None | 0.49A | 6gp2A-4bmrA:37.8 | 6gp2A-4bmrA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmr | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillus cereus) |
PF00268(Ribonuc_red_sm) | 6 | LEU A 58THR A 59ILE A 103PHE A 104PHE A 169ILE A 191 | None | 0.64A | 6gp2A-4bmrA:37.8 | 6gp2A-4bmrA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ckb | MRNA-CAPPING ENZYMECATALYTIC SUBUNIT (Vaccinia virus) |
PF03291(Pox_MCEL)PF10640(Pox_ATPase-GT) | 6 | LEU A 700THR A 701PHE A 780PHE A 659ILE A 654ILE A 597 | None | 1.13A | 6gp2A-4ckbA:undetectable | 6gp2A-4ckbA:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7q | RALF,PROLINE/BETAINETRANSPORTER (Legionellapneumophila;Rickettsiaprowazekii) |
PF01369(Sec7) | 5 | THR A 215ASP A 213ILE A 316PHE A 233ILE A 205 | None | 1.04A | 6gp2A-4d7qA:undetectable | 6gp2A-4d7qA:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 7 | LEU A 62ASP A 66SER A 104ILE A 108PHE A 172ILE A 191ILE A 194 | None MN A 402 (-2.3A)NoneNoneNoneNoneNone | 0.79A | 6gp2A-4dr0A:37.9 | 6gp2A-4dr0A:12.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dr0 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Bacillussubtilis) |
PF00268(Ribonuc_red_sm) | 8 | LEU A 62THR A 63SER A 104ILE A 108PHE A 109PHE A 172ILE A 191ILE A 194 | None | 0.62A | 6gp2A-4dr0A:37.9 | 6gp2A-4dr0A:12.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fd0 | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidescaccae) |
PF07523(Big_3)PF13306(LRR_5) | 5 | PHE A 294GLY A 268ILE A 267PHE A 332ILE A 318 | NoneSO4 A 512 ( 4.3A)NoneNoneNone | 1.02A | 6gp2A-4fd0A:undetectable | 6gp2A-4fd0A:11.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 87GLY A 106ILE A 82ILE A 96ILE A 119 | None | 0.97A | 6gp2A-4fs7A:undetectable | 6gp2A-4fs7A:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 6 | PHE A 133GLY A 152ILE A 128PHE A 161ILE A 142ILE A 164 | None | 1.41A | 6gp2A-4fs7A:undetectable | 6gp2A-4fs7A:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fs7 | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF13306(LRR_5) | 5 | PHE A 336GLY A 355ILE A 331ILE A 345ILE A 368 | None | 0.82A | 6gp2A-4fs7A:undetectable | 6gp2A-4fs7A:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdu | AEROTOLERANCE-RELATED MEMBRANE PROTEIN (Bacteroidesfragilis) |
PF00092(VWA) | 5 | ASP A 129GLY A 132ILE A 94ILE A 283ILE A 287 | None | 0.85A | 6gp2A-4jduA:undetectable | 6gp2A-4jduA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 59LEU A 62ASP A 66SER A 103ILE A 107PHE A 108PHE A 165ILE A 184ILE A 187 | NoneNone MN A 402 (-2.8A)NoneNoneNoneNoneNoneNone | 0.66A | 6gp2A-4n83A:37.8 | 6gp2A-4n83A:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n83 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASESUBUNIT BETA (Streptococcussanguinis) |
PF00268(Ribonuc_red_sm) | 9 | PHE A 59LEU A 62THR A 63SER A 103ILE A 107PHE A 108PHE A 165ILE A 184ILE A 187 | None | 0.54A | 6gp2A-4n83A:37.8 | 6gp2A-4n83A:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ouq | UNCHARACTERIZEDPROTEIN (Bacteroidesfragilis) |
PF16022(DUF4783) | 5 | PHE A 71THR A 67PHE A 32ILE A 107ILE A 123 | None | 0.92A | 6gp2A-4ouqA:undetectable | 6gp2A-4ouqA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p5w | CALCIUM-BINDINGMITOCHONDRIALCARRIER PROTEINARALAR2,CALCIUM-BINDING MITOCHONDRIALCARRIER PROTEINARALAR2 (Homo sapiens) |
no annotation | 5 | THR A 265GLY A 222ILE A 271PHE A 254ILE A 233 | None | 0.96A | 6gp2A-4p5wA:undetectable | 6gp2A-4p5wA:12.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9d | BENZOYLFORMATEDECARBOXYLASE (Mycolicibacteriumsmegmatis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | LEU A 385THR A 381GLY A 433ILE A 432PHE A 397 | NoneNoneFMT A 603 (-3.3A)NoneNone | 0.95A | 6gp2A-4q9dA:undetectable | 6gp2A-4q9dA:8.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qku | HYDROLASE (Burkholderiacenocepacia) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 245GLY A 364ILE A 366PHE A 420ILE A 312 | None | 0.99A | 6gp2A-4qkuA:undetectable | 6gp2A-4qkuA:10.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rhm | ARGINASE (Trypanosomabrucei) |
PF00491(Arginase) | 5 | LEU A 28GLY A 263PHE A 45ILE A 292ILE A 296 | None | 1.06A | 6gp2A-4rhmA:undetectable | 6gp2A-4rhmA:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxs | VIRION EGRESSPROTEIN UL34 (Humanalphaherpesvirus1) |
PF04541(Herpes_U34) | 5 | LEU A 85GLY A 109ILE A 111ILE A 153ILE A 87 | None | 1.04A | 6gp2A-4zxsA:undetectable | 6gp2A-4zxsA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aex | AMMONIUM TRANSPORTERMEP2 (Saccharomycescerevisiae) |
PF00909(Ammonium_transp) | 5 | LEU A 56GLY A 142ILE A 49ILE A 297ILE A 347 | None | 1.05A | 6gp2A-5aexA:undetectable | 6gp2A-5aexA:10.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d7a | TRAF2 ANDNCK-INTERACTINGPROTEIN KINASE (Homo sapiens) |
PF00069(Pkinase) | 5 | LEU A 283THR A 280GLY A 140ILE A 137ILE A 289 | LEU A 283 ( 0.6A)THR A 280 ( 0.8A)GLY A 140 ( 0.0A)ILE A 137 ( 0.7A)ILE A 289 ( 0.7A) | 1.08A | 6gp2A-5d7aA:undetectable | 6gp2A-5d7aA:12.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ekp | UNCHARACTERIZEDGLYCOSYLTRANSFERASESLL0501 (Synechocystissp. PCC 6803) |
no annotation | 5 | PHE C 22LEU C 25ILE C 63ILE C 9ILE C 7 | None | 1.06A | 6gp2A-5ekpC:undetectable | 6gp2A-5ekpC:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | PHE A 168LEU A 173SER A 218GLY A 192ILE A 191 | None | 0.98A | 6gp2A-5gr8A:undetectable | 6gp2A-5gr8A:8.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h5b | THYMIDYLATE KINASE (Aquifexaeolicus) |
no annotation | 5 | LEU B 24ILE B 185PHE B 182ILE B 3ILE B 87 | None | 1.07A | 6gp2A-5h5bB:undetectable | 6gp2A-5h5bB:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h80 | CARBOXYLASE (Deinococcusradiodurans) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | PHE A 364LEU A 382GLY A 422ILE A 420PHE A 377 | None | 1.07A | 6gp2A-5h80A:undetectable | 6gp2A-5h80A:8.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hiu | GTPASEACTIVATOR-LIKEPROTEIN (Chaetomiumthermophilum) |
PF11864(DUF3384) | 6 | PHE A 207LEU A 210THR A 211GLY A 276ILE A 274ILE A 262 | PHE A 207 ( 1.3A)LEU A 210 ( 0.5A)THR A 211 ( 0.8A)GLY A 276 ( 0.0A)ILE A 274 ( 0.7A)ILE A 262 ( 0.7A) | 0.95A | 6gp2A-5hiuA:undetectable | 6gp2A-5hiuA:10.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huq | LACTATE RACEMIZATIONOPERON PROTEIN LARA (Lactobacillusplantarum) |
PF09861(DUF2088) | 5 | SER A 250GLY A 249ILE A 247ILE A 82ILE A 237 | None | 0.93A | 6gp2A-5huqA:undetectable | 6gp2A-5huqA:10.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j4r | WELO5 (Hapalosiphonwelwitschii) |
no annotation | 5 | PHE A 120ILE A 192PHE A 47PHE A 106ILE A 152 | None | 1.08A | 6gp2A-5j4rA:undetectable | 6gp2A-5j4rA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0y | CELLULOSOMEANCHORING PROTEINCOHESIN REGION (Ruminiclostridiumthermocellum) |
PF00963(Cohesin) | 5 | LEU A 85GLY A 81ILE A 128PHE A 48ILE A 42 | NoneP6G A 205 (-3.6A)P6G A 205 (-4.9A)NoneNone | 0.90A | 6gp2A-5m0yA:undetectable | 6gp2A-5m0yA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mso | CARBOXYLIC ACIDREDUCTASE (Mycobacteriummarinum) |
PF07993(NAD_binding_4) | 5 | LEU A1071ILE A1085PHE A1002ILE A1006ILE A1161 | None | 0.93A | 6gp2A-5msoA:undetectable | 6gp2A-5msoA:5.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 5 | ASP A 254SER A 628GLY A 727ILE A 731ILE A 626 | None | 1.00A | 6gp2A-5nd1A:undetectable | 6gp2A-5nd1A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5szs | SPIKE GLYCOPROTEIN (HumancoronavirusNL63) |
PF01600(Corona_S1)PF01601(Corona_S2) | 5 | LEU A 151THR A 159ILE A 144ILE A 89ILE A 105 | None | 1.00A | 6gp2A-5szsA:undetectable | 6gp2A-5szsA:4.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti1 | FUMARYLACETOACETATEHYDROLASE (Paraburkholderiaxenovorans) |
PF01557(FAA_hydrolase)PF09298(FAA_hydrolase_N) | 5 | LEU A 249GLY A 368ILE A 370PHE A 424ILE A 316 | None MG A 501 ( 4.7A)NoneNoneNone | 0.97A | 6gp2A-5ti1A:undetectable | 6gp2A-5ti1A:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ucd | NAD(P)-DEPENDENTBENZALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00171(Aldedh) | 5 | LEU A 127GLY A 132ILE A 134ILE A 159ILE A 142 | None | 0.92A | 6gp2A-5ucdA:undetectable | 6gp2A-5ucdA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uco | 2,4,6-TRIHYDROXYBENZOPHENONE SYNTHASE (Hypericumandrosaemum) |
no annotation | 5 | PHE A 73LEU A 75THR A 76ILE A 34PHE A 201 | None | 1.00A | 6gp2A-5ucoA:undetectable | 6gp2A-5ucoA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z2g | L-AMINO ACID OXIDASE (Naja atra) |
no annotation | 5 | PHE A 398LEU A 401ASP A 402ILE A 344ILE A 409 | None | 0.94A | 6gp2A-5z2gA:undetectable | 6gp2A-5z2gA:18.09 |