SIMILAR PATTERNS OF AMINO ACIDS FOR 6GNG_A_QPSA601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c9w | CHO REDUCTASE (Cricetulusgriseus) |
PF00248(Aldo_ket_red) | 5 | GLY A 114VAL A 130GLY A 157ASN A 305GLN A 165 | None | 1.00A | 6gngA-1c9wA:undetectable | 6gngA-1c9wA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm3 | BIOSYNTHETICTHIOLASE ACETYLATEDAT CYS89 (Zoogloearamigera) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | GLY A 341VAL A 337GLY A 16ASN A 316ASN A 327 | None | 1.12A | 6gngA-1dm3A:undetectable | 6gngA-1dm3A:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e4o | MALTODEXTRINPHOSPHORYLASE (Escherichiacoli) |
PF00343(Phosphorylase) | 5 | GLY A 113LEU A 115ASP A 307HIS A 309ASN A 449 | GLC A 997 (-3.3A)GLC A 997 (-3.8A)GLC A 997 (-3.6A)GLC A 996 (-4.0A)GLC A 998 (-3.3A) | 0.59A | 6gngA-1e4oA:23.1 | 6gngA-1e4oA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp2 | ISOFLAVONEO-METHYLTRANSFERASE (Medicago sativa) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 5 | LEU A 345THR A 201GLY A 200ASP A 194ASP A 288 | NoneNoneNoneSAH A1699 ( 4.6A)None | 1.18A | 6gngA-1fp2A:2.2 | 6gngA-1fp2A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gkr | NON-ATP DEPENDENTL-SELECTIVEHYDANTOINASE (Paenarthrobacteraurescens) |
PF01979(Amidohydro_1) | 5 | GLY A 444LEU A 117THR A 431GLY A 430ASP A 388 | None | 1.16A | 6gngA-1gkrA:2.7 | 6gngA-1gkrA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i78 | PROTEASE VII (Escherichiacoli) |
PF01278(Omptin) | 5 | THR A 184GLY A 185LEU A 128GLY A 67ASN A 122 | None | 1.19A | 6gngA-1i78A:undetectable | 6gngA-1i78A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8a | ENDO-1,4-BETA-XYLANASE A (Thermotogamaritima) |
PF06452(CBM9_1) | 5 | GLY A 88THR A 109GLY A 108ASP A 169ASN A 173 | NoneNoneBGC A 189 ( 4.3A)NoneNone | 1.04A | 6gngA-1i8aA:undetectable | 6gngA-1i8aA:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcx | DIHYDROPYRIMIDINASERELATED PROTEIN-1 (Mus musculus) |
PF01979(Amidohydro_1) | 5 | THR A 74GLY A 332THR A 101GLY A 100ASN A 356 | None | 1.20A | 6gngA-1kcxA:undetectable | 6gngA-1kcxA:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kny | KANAMYCINNUCLEOTIDYLTRANSFERASE (Staphylococcusaureus) |
PF07827(KNTase_C) | 5 | GLY A 173VAL A 191THR A 238GLY A 242HIS A 181 | None | 1.14A | 6gngA-1knyA:undetectable | 6gngA-1knyA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kol | FORMALDEHYDEDEHYDROGENASE (Pseudomonasputida) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 133LEU A 65VAL A 6GLY A 120ASP A 49 | None | 1.15A | 6gngA-1kolA:3.9 | 6gngA-1kolA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kxh | ALPHA-AMYLASE (Pseudoalteromonashaloplanktis) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C) | 5 | THR A 221VAL A 197GLY A 270ASP A 84ASN A 174 | CL A 900 ( 4.4A)NoneNoneNoneACR A 598 (-3.2A) | 1.16A | 6gngA-1kxhA:undetectable | 6gngA-1kxhA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lfw | PEPV (Lactobacillusdelbrueckii) |
PF01546(Peptidase_M20) | 5 | GLY A 116VAL A 91GLY A 110ASP A 107GLN A 430 | None | 1.12A | 6gngA-1lfwA:3.2 | 6gngA-1lfwA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nd7 | WW DOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00632(HECT) | 5 | GLY A 860LEU A 858THR A 851GLY A 852GLN A 805 | None | 0.98A | 6gngA-1nd7A:undetectable | 6gngA-1nd7A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p9b | ADENYLOSUCCINATESYNTHETASE (Plasmodiumfalciparum) |
PF00709(Adenylsucc_synt) | 5 | THR A 242GLY A 241VAL A 326ASN A 232ASN A 330 | NoneNoneNoneIMO A1601 (-3.7A)None | 1.07A | 6gngA-1p9bA:undetectable | 6gngA-1p9bA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rzv | GLYCOGEN SYNTHASE 1 (Agrobacteriumtumefaciens) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 7 | THR A 16GLY A 17LEU A 19VAL A 22ASP A 103ASP A 138ASN A 246 | None | 0.76A | 6gngA-1rzvA:40.5 | 6gngA-1rzvA:28.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v47 | ATP SULFURYLASE (Thermusthermophilus) |
PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | THR A 23GLY A 24LEU A 21VAL A 29ASP A 17 | None | 1.18A | 6gngA-1v47A:3.5 | 6gngA-1v47A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 6 | GLY A 134LEU A 136ASP A 283ASP A 339HIS A 341ASN A 484 | PO4 A1900 (-3.7A)NoneNoneNoneNoneNone | 0.99A | 6gngA-1ygpA:20.7 | 6gngA-1ygpA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yzy | HYPOTHETICAL PROTEINHI1011 (Haemophilusinfluenzae) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | THR A 217GLY A 218LEU A 222THR A 163GLY A 164 | None | 1.12A | 6gngA-1yzyA:undetectable | 6gngA-1yzyA:23.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2avd | CATECHOL-O-METHYLTRANSFERASE (Homo sapiens) |
PF01596(Methyltransf_3) | 5 | LEU A 77THR A 111GLY A 110ASP A 185ASP A 83 | NoneNoneSAM A 501 (-3.4A)SAM A 501 (-3.4A)None | 1.03A | 6gngA-2avdA:3.5 | 6gngA-2avdA:16.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2azq | CATECHOL1,2-DIOXYGENASE (Pseudomonasputida) |
PF00775(Dioxygenase_C)PF04444(Dioxygenase_N) | 5 | GLY A 195VAL A 192GLY A 76HIS A 222ASN A 238 | NoneNoneNone FE A 400 (-3.2A)None | 1.04A | 6gngA-2azqA:undetectable | 6gngA-2azqA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 5 | GLY A 113LEU A 115ASP A 248ASP A 296ASN A 437 | PO4 A1794 (-3.5A)NoneNoneNoneFMT A1799 (-3.5A) | 1.01A | 6gngA-2c4mA:22.4 | 6gngA-2c4mA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 5 | GLY A 113LEU A 115ASP A 296HIS A 298ASN A 437 | PO4 A1794 (-3.5A)NoneNoneNoneFMT A1799 (-3.5A) | 0.80A | 6gngA-2c4mA:22.4 | 6gngA-2c4mA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cev | PROTEIN (ARGINASE) ([Bacillus]caldovelox) |
PF00491(Arginase) | 5 | THR A 105GLY A 104VAL A 71GLY A 117HIS A 99 | NoneNoneNoneNone MN A 301 ( 3.2A) | 1.08A | 6gngA-2cevA:2.6 | 6gngA-2cevA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cx9 | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | THR A 160LEU A 95VAL A 169GLY A 83ASN A 93 | None | 1.10A | 6gngA-2cx9A:undetectable | 6gngA-2cx9A:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e8y | AMYX PROTEIN (Bacillussubtilis) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 5 | LEU A 451VAL A 511THR A 441GLY A 369ASP A 465 | None | 1.04A | 6gngA-2e8yA:undetectable | 6gngA-2e8yA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gdu | SUCROSEPHOSPHORYLASE (Bifidobacteriumadolescentis) |
PF00128(Alpha-amylase)PF09244(DUF1964) | 5 | LEU A 341GLY A 197ASP A 50ASN A 347GLN A 232 | SUC A2064 (-4.7A)NoneSUC A2064 (-2.6A)NoneSUC A2064 (-2.7A) | 0.97A | 6gngA-2gduA:undetectable | 6gngA-2gduA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gj4 | GLYCOGENPHOSPHORYLASE,MUSCLE FORM (Oryctolaguscuniculus) |
PF00343(Phosphorylase) | 5 | GLY A 134LEU A 136ASP A 339HIS A 341ASN A 484 | PLR A 940 (-3.6A)NoneNoneNoneNone | 0.88A | 6gngA-2gj4A:21.8 | 6gngA-2gj4A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k2s | MICRONEMAL PROTEIN 1 (Toxoplasmagondii) |
PF11476(TgMIC1) | 5 | GLY A 74LEU A 19VAL A 125THR A 51GLY A 52 | None | 1.20A | 6gngA-2k2sA:undetectable | 6gngA-2k2sA:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o96 | 26S PROTEASOMENON-ATPASEREGULATORY SUBUNIT 7 (Homo sapiens) |
PF01398(JAB) | 5 | GLY A 27THR A 97GLY A 98ASP A 125GLN A 32 | None | 1.16A | 6gngA-2o96A:undetectable | 6gngA-2o96A:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qk4 | TRIFUNCTIONAL PURINEBIOSYNTHETIC PROTEINADENOSINE-3 (Homo sapiens) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 5 | GLY A 73THR A 39GLY A 38ASN A 290GLN A 299 | None | 0.99A | 6gngA-2qk4A:4.8 | 6gngA-2qk4A:24.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3e | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Pseudomonasaeruginosa) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | THR A 112GLY A 308VAL A 305GLY A 185ASP A 180 | None | 1.08A | 6gngA-2x3eA:undetectable | 6gngA-2x3eA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 5 | GLY A 134LEU A 136ASP A 339HIS A 341ASN A 484 | PLP A 832 (-3.6A)NBG A 1 (-4.1A)NoneNoneNBG A 1 (-3.3A) | 0.89A | 6gngA-3cemA:22.2 | 6gngA-3cemA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | THR A 16ASP A 137HIS A 139ASN A 162ASN A 246 | None | 1.00A | 6gngA-3d1jA:40.8 | 6gngA-3d1jA:29.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 7 | THR A 16GLY A 17LEU A 19VAL A 22ASP A 137HIS A 139ASN A 246 | None | 0.77A | 6gngA-3d1jA:40.8 | 6gngA-3d1jA:29.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 5 | THR A 433GLY A 432VAL A 397THR A 529GLY A 527 | None | 1.18A | 6gngA-3eqnA:undetectable | 6gngA-3eqnA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gp6 | PROTEIN PAGP (Escherichiacoli) |
PF07017(PagP) | 5 | GLY A 88THR A 137GLY A 132ASP A 61ASN A 65 | SDS A 163 ( 4.7A)NoneSDS A 166 (-3.3A)NoneNone | 1.16A | 6gngA-3gp6A:undetectable | 6gngA-3gp6A:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4x | PHOSPHATIDYLINOSITOL-SPECIFICPHOSPHOLIPASE C1 (Streptomycesantibioticus) |
PF16670(PI-PLC-C1) | 5 | THR A 209GLY A 133GLY A 237ASP A 260ASP A 62 | NoneNoneNoneEOH A 358 (-4.1A)None | 1.14A | 6gngA-3h4xA:undetectable | 6gngA-3h4xA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hl0 | MALEYLACETATEREDUCTASE (Agrobacteriumfabrum) |
PF00465(Fe-ADH) | 5 | GLY A 234THR A 138GLY A 129HIS A 174ASN A 185 | None | 1.03A | 6gngA-3hl0A:3.8 | 6gngA-3hl0A:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hu5 | ISOCHORISMATASEFAMILY PROTEIN (Desulfovibriovulgaris) |
PF00857(Isochorismatase) | 5 | GLY A 88VAL A 92GLY A 64ASP A 66ASP A 15 | None | 0.94A | 6gngA-3hu5A:5.3 | 6gngA-3hu5A:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hu5 | ISOCHORISMATASEFAMILY PROTEIN (Desulfovibriovulgaris) |
PF00857(Isochorismatase) | 5 | THR A 86GLY A 88VAL A 92GLY A 64ASP A 66 | None | 1.19A | 6gngA-3hu5A:5.3 | 6gngA-3hu5A:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzt | CALCIUM-DEPENDENTPROTEIN KINASE 3 (Toxoplasmagondii) |
PF00069(Pkinase)PF13499(EF-hand_7) | 5 | GLY A 276VAL A 287GLY A 490ASP A 280GLN A 363 | None | 0.89A | 6gngA-3hztA:undetectable | 6gngA-3hztA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khj | INOSINE-5-MONOPHOSPHATE DEHYDROGENASE (Cryptosporidiumparvum) |
PF00478(IMPDH) | 5 | GLY A 67LEU A 45VAL A 345THR A 36GLY A 208 | None | 1.17A | 6gngA-3khjA:undetectable | 6gngA-3khjA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kl4 | SIGNAL RECOGNITION54 KDA PROTEIN (Sulfolobussolfataricus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 5 | GLY A 293LEU A 292VAL A 288THR A 14GLY A 15 | None | 1.17A | 6gngA-3kl4A:2.4 | 6gngA-3kl4A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krn | PROTEIN C14A4.5,CONFIRMED BYTRANSCRIPT EVIDENCE (Caenorhabditiselegans) |
PF01138(RNase_PH) | 5 | GLY A 129LEU A 156GLY A 97ASP A 100ASN A 71 | None | 1.15A | 6gngA-3krnA:undetectable | 6gngA-3krnA:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l01 | GLGA GLYCOGENSYNTHASE (Pyrococcusabyssi) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | GLY A 16LEU A 18ASP A 128HIS A 130ASN A 217 | CL A5703 ( 3.9A)GOL A6500 ( 4.3A)GOL A6500 (-3.2A)GOL A6502 ( 3.8A)None | 0.99A | 6gngA-3l01A:34.6 | 6gngA-3l01A:26.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l01 | GLGA GLYCOGENSYNTHASE (Pyrococcusabyssi) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | GLY A 17LEU A 18ASP A 128HIS A 130ASN A 217 | CL A5703 (-4.7A)GOL A6500 ( 4.3A)GOL A6500 (-3.2A)GOL A6502 ( 3.8A)None | 0.93A | 6gngA-3l01A:34.6 | 6gngA-3l01A:26.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3si9 | DIHYDRODIPICOLINATESYNTHASE (Bartonellahenselae) |
PF00701(DHDPS) | 5 | GLY A 191LEU A 189THR A 108ASN A 200GLN A 178 | None | 1.08A | 6gngA-3si9A:undetectable | 6gngA-3si9A:23.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vue | GRANULE-BOUND STARCHSYNTHASE 1,CHLOROPLASTIC/AMYLOPLASTIC (Oryza sativa) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 7 | THR A 98GLY A 99LEU A 101VAL A 104HIS A 236ASN A 353GLN A 412 | NoneSO4 A 704 (-3.2A)NoneNoneNoneNoneSO4 A 704 ( 3.7A) | 0.78A | 6gngA-3vueA:47.9 | 6gngA-3vueA:46.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3vue | GRANULE-BOUND STARCHSYNTHASE 1,CHLOROPLASTIC/AMYLOPLASTIC (Oryza sativa) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 8 | THR A 98LEU A 101VAL A 104ASP A 234HIS A 236ASN A 265ASN A 353GLN A 412 | NoneNoneNoneNoneNoneSO4 A 704 ( 4.2A)NoneSO4 A 704 ( 3.7A) | 0.78A | 6gngA-3vueA:47.9 | 6gngA-3vueA:46.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wy7 | 8-AMINO-7-OXONONANOATE SYNTHASE (Mycolicibacteriumsmegmatis) |
PF00155(Aminotran_1_2) | 5 | GLY A 214LEU A 216VAL A 219THR A 232GLY A 104 | None | 1.07A | 6gngA-3wy7A:2.1 | 6gngA-3wy7A:24.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zeu | PROBABLE TRNATHREONYLCARBAMOYLADENOSINE BIOSYNTHESISPROTEIN GCP (Salmonellaenterica) |
PF00814(Peptidase_M22) | 5 | THR B 258GLY B 259LEU B 255THR B 146GLY B 147 | None | 1.04A | 6gngA-3zeuB:2.5 | 6gngA-3zeuB:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyv | AOX3 (Mus musculus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | GLY A 373LEU A 372VAL A 416GLY A 465HIS A 358 | NoneNoneNoneNoneFAD A3005 (-3.8A) | 0.81A | 6gngA-3zyvA:undetectable | 6gngA-3zyvA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bqi | ALPHA-GLUCANPHOSPHORYLASE 2,CYTOSOLIC (Arabidopsisthaliana) |
PF00343(Phosphorylase) | 5 | GLY A 137LEU A 139ASP A 341HIS A 343ASN A 487 | PLP A 901 ( 4.2A)NoneNoneNoneNone | 0.84A | 6gngA-4bqiA:22.4 | 6gngA-4bqiA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bqi | ALPHA-GLUCANPHOSPHORYLASE 2,CYTOSOLIC (Arabidopsisthaliana) |
PF00343(Phosphorylase) | 5 | GLY A 137LEU A 139GLY A 287ASP A 341HIS A 343 | PLP A 901 ( 4.2A)NoneNoneNoneNone | 1.08A | 6gngA-4bqiA:22.4 | 6gngA-4bqiA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dza | LYSINE RACEMASE (Proteusmirabilis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 5 | GLY A 98VAL A 136GLY A 79ASP A 81ASN A 101 | None | 1.04A | 6gngA-4dzaA:undetectable | 6gngA-4dzaA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i7u | DIHYDRODIPICOLINATESYNTHASE (Agrobacteriumsp. H13-3) |
PF00701(DHDPS) | 5 | GLY A 187LEU A 185THR A 104ASN A 196GLN A 174 | None | 1.07A | 6gngA-4i7uA:undetectable | 6gngA-4i7uA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igm | 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDEDECARBOXYLASE (Homo sapiens) |
PF04909(Amidohydro_2) | 5 | THR A 116GLY A 115LEU A 100THR A 89ASN A 98 | None | 1.15A | 6gngA-4igmA:undetectable | 6gngA-4igmA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jlw | GLUTATHIONE-INDEPENDENT FORMALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 134LEU A 66VAL A 7GLY A 121ASP A 50 | None | 1.15A | 6gngA-4jlwA:2.8 | 6gngA-4jlwA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jn6 | ACETALDEHYDEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF01118(Semialdhyde_dh)PF09290(AcetDehyd-dimer) | 5 | GLY B 129THR B 163GLY B 162ASN B 123ASN B 112 | None | 0.91A | 6gngA-4jn6B:3.2 | 6gngA-4jn6B:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l22 | PHOSPHORYLASE (Streptococcusmutans) |
PF00343(Phosphorylase) | 5 | GLY A 104LEU A 106ASP A 279HIS A 281ASN A 413 | None | 0.73A | 6gngA-4l22A:23.1 | 6gngA-4l22A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8j | L-CARNITINE/GAMMA-BUTYROBETAINEANTIPORTER (Proteusmirabilis) |
PF02028(BCCT) | 5 | THR A 206GLY A 205LEU A 202VAL A 22GLN A 330 | None | 1.12A | 6gngA-4m8jA:undetectable | 6gngA-4m8jA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mju | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 5 | GLY A 193VAL A 214THR A 135GLY A 137ASN A 216 | None | 1.16A | 6gngA-4mjuA:undetectable | 6gngA-4mjuA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n03 | ABC-TYPEBRANCHED-CHAIN AMINOACID TRANSPORTSYSTEMS PERIPLASMICCOMPONENT-LIKEPROTEIN (Thermomonosporacurvata) |
PF13458(Peripla_BP_6) | 5 | THR A 353GLY A 356LEU A 357THR A 36GLY A 37 | None | 1.16A | 6gngA-4n03A:2.2 | 6gngA-4n03A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nf2 | ORNITHINECARBAMOYLTRANSFERASE (Bacillusanthracis) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 171VAL A 167THR A 207GLY A 208ASN A 165 | NoneNoneNoneNoneNVA A 402 (-3.8A) | 1.18A | 6gngA-4nf2A:2.1 | 6gngA-4nf2A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pet | EXTRACELLULARSOLUTE-BINDINGPROTEIN, FAMILY 7 (Colwelliapsychrerythraea) |
PF03480(DctP) | 5 | GLY A 185LEU A 188THR A 244GLY A 243ASN A 316 | NoneNonePYR A 402 ( 4.1A)NoneNone | 1.12A | 6gngA-4petA:undetectable | 6gngA-4petA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rsm | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Mycolicibacteriumsmegmatis) |
PF13407(Peripla_BP_4) | 5 | THR A 335GLY A 336LEU A 333VAL A 291GLY A 342 | None | 1.20A | 6gngA-4rsmA:3.5 | 6gngA-4rsmA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uph | SULFATASE (SULFURICESTER HYDROLASE)PROTEIN (Agrobacteriumtumefaciens) |
PF00884(Sulfatase)PF16347(DUF4976) | 5 | GLY A 51LEU A 53VAL A 368GLY A 306ASP A 302 | None | 1.16A | 6gngA-4uphA:undetectable | 6gngA-4uphA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wwv | AMINOPEPTIDASE FROMFAMILY M42 (Desulfurococcusamylolyticus) |
PF05343(Peptidase_M42) | 5 | THR A 320GLY A 319VAL A 316THR A 239ASP A 184 | None | 1.16A | 6gngA-4wwvA:undetectable | 6gngA-4wwvA:25.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zht | BIFUNCTIONALUDP-N-ACETYLGLUCOSAMINE2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE (Homo sapiens) |
PF02350(Epimerase_2) | 5 | GLY A 299LEU A 218VAL A 216GLY A 140ASP A 143 | NoneUDP A 501 (-4.3A)NoneNoneNone | 1.12A | 6gngA-4zhtA:14.1 | 6gngA-4zhtA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ahk | ACETOLACTATESYNTHASE II, LARGESUBUNIT (Pseudomonasprotegens) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | GLY A 448VAL A 470THR A 83GLY A 84GLN A 454 | TPP A 700 (-3.7A)NoneNoneNoneNone | 1.19A | 6gngA-5ahkA:2.2 | 6gngA-5ahkA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7i | CRISPR-ASSOCIATEDNUCLEASE/HELICASECAS3 SUBTYPEI-F/YPEST (Pseudomonasaeruginosa) |
no annotation | 5 | GLY A 451VAL A 574GLY A 886ASN A 430GLN A 847 | NoneNoneNoneNoneADP A1103 (-3.7A) | 1.11A | 6gngA-5b7iA:undetectable | 6gngA-5b7iA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bsz | N-METHYLTRANSFERASE (Streptoalloteichussp. ATCC 53650) |
PF13649(Methyltransf_25) | 5 | GLY A 140LEU A 142VAL A 240GLY A 103ASP A 101 | None | 1.13A | 6gngA-5bszA:undetectable | 6gngA-5bszA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cer | BD0816BD3460 (Bdellovibriobacteriovorus) |
PF02113(Peptidase_S13)PF12796(Ank_2) | 5 | THR A 346GLY A 347GLY A 335ASN B 106ASN A 350 | None | 1.16A | 6gngA-5cerA:undetectable | 6gngA-5cerA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gin | FIBRILLARIN-LIKERRNA/TRNA2'-O-METHYLTRANSFERASE (Sulfolobussolfataricus) |
PF01269(Fibrillarin) | 5 | THR E 89GLY E 88VAL E 114GLY E 63ASP E 220 | A I 6 ( 3.5A)NoneNoneNone G I 5 ( 3.8A) | 0.99A | 6gngA-5ginE:2.5 | 6gngA-5ginE:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikp | GLYCOGENPHOSPHORYLASE, BRAINFORM (Homo sapiens) |
PF00343(Phosphorylase) | 5 | GLY A 134LEU A 136ASP A 339HIS A 341ASN A 484 | PLP A 901 ( 4.1A)NoneNoneNoneNone | 0.73A | 6gngA-5ikpA:21.5 | 6gngA-5ikpA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE GAMMASUBUNIT (Aromatoleumaromaticum) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 5 | GLY B 19THR B 312GLY B 310ASP B 308ASP B 23 | None | 1.12A | 6gngA-5l9wB:2.7 | 6gngA-5l9wB:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lrb | ALPHA-1,4 GLUCANPHOSPHORYLASE (Hordeum vulgare) |
PF00343(Phosphorylase) | 5 | GLY A 181LEU A 183ASP A 383HIS A 385ASN A 613 | PLP A1002 ( 4.3A)GLC A1001 (-4.3A)NoneNoneGLC A1001 (-3.8A) | 0.79A | 6gngA-5lrbA:22.4 | 6gngA-5lrbA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lrb | ALPHA-1,4 GLUCANPHOSPHORYLASE (Hordeum vulgare) |
PF00343(Phosphorylase) | 5 | GLY A 181LEU A 183GLY A 331ASP A 383HIS A 385 | PLP A1002 ( 4.3A)GLC A1001 (-4.3A)NoneNoneNone | 1.10A | 6gngA-5lrbA:22.4 | 6gngA-5lrbA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lta | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE PRP43 (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | LEU A 90THR A 78GLY A 79ASP A 71ASN A 99 | None | 1.17A | 6gngA-5ltaA:undetectable | 6gngA-5ltaA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | 2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN2,4-DIACETYLPHLOROGLUCINOL BIOSYNTHESISPROTEIN PHLC (Pseudomonasprotegens) |
no annotation | 5 | GLY C 249VAL B 94THR C 256GLY B 49ASP B 98 | None | 0.96A | 6gngA-5mg5C:undetectable | 6gngA-5mg5C:9.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oei | UNCHARACTERIZEDPROTEIN FAMILYUPF0065:TAT PATHWAYSIGNAL (Rhodopseudomonaspalustris) |
no annotation | 5 | GLY A 103VAL A 45THR A 174GLY A 175ASP A 215 | NoneNoneOOG A 401 (-3.1A)NoneOOG A 401 ( 4.7A) | 1.05A | 6gngA-5oeiA:2.1 | 6gngA-5oeiA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol2 | ACYL-COADEHYDROGENASE (Clostridioidesdifficile) |
no annotation | 5 | THR C 157LEU C 92VAL C 166THR C 81GLY C 80 | FAD C 401 (-3.7A)NoneNoneNoneNone | 1.15A | 6gngA-5ol2C:undetectable | 6gngA-5ol2C:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy0 | PHOTOSYSTEM I P700CHLOROPHYLL AAPOPROTEIN A1PHOTOSYSTEM IREACTION CENTERSUBUNIT II (Synechocystissp. PCC 6803) |
no annotation | 5 | GLY 4 46VAL 1 422GLY 1 569ASP 1 417GLN 4 71 | None | 1.13A | 6gngA-5oy04:undetectable | 6gngA-5oy04:9.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5th5 | 7-CARBOXY-7-DEAZAGUANINE SYNTHASE (Bacillussubtilis) |
PF04055(Radical_SAM)PF13394(Fer4_14) | 5 | THR A 234GLY A 238LEU A 236GLY A 208GLN A 200 | None | 1.13A | 6gngA-5th5A:2.8 | 6gngA-5th5A:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tlc | DIBENZOTHIOPHENEDESULFURIZATIONENZYME A (Bacillussubtilis) |
PF00296(Bac_luciferase) | 5 | GLY A 60VAL A 137GLY A 78HIS A 316ASN A 135 | None | 1.18A | 6gngA-5tlcA:undetectable | 6gngA-5tlcA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5up2 | N-METHYL-D-ASPARTATERECEPTOR SUBUNITNR2A (Xenopus laevis) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | GLY B 498LEU B 399VAL B 397THR B 519GLY B 520 | None | 1.06A | 6gngA-5up2B:undetectable | 6gngA-5up2B:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vfr | 26S PROTEASOMENON-ATPASEREGULATORY SUBUNIT1126S PROTEASOMEREGULATORY SUBUNIT6B (Homo sapiens) |
no annotation | 5 | GLY X 273LEU X 275GLY D 169ASP D 171ASP X 240 | None | 0.98A | 6gngA-5vfrX:undetectable | 6gngA-5vfrX:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vld | HISTIDINOLDEHYDROGENASE,CHLOROPLASTIC (Medicagotruncatula) |
PF00815(Histidinol_dh) | 5 | GLY A 248VAL A 254GLY A 217ASN A 197ASN A 251 | NoneNAD A 502 ( 4.9A)NoneNoneNAD A 502 (-3.2A) | 1.14A | 6gngA-5vldA:undetectable | 6gngA-5vldA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITDNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF00623(RNA_pol_Rpb1_2)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 6 | GLY A 662LEU A 659THR A 540GLY A 575ASN A 655ASN B 834 | None | 1.41A | 6gngA-5xogA:undetectable | 6gngA-5xogA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | LEU B 373GLY B 58ASP B 138HIS B 323ASN B 378 | NAD B 501 ( 3.9A)NoneNone ZN B 505 (-3.2A)None | 1.18A | 6gngA-6f3mB:6.3 | 6gngA-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fwf | NITRIC-OXIDEREDUCTASE (Neisseriameningitidis) |
no annotation | 5 | THR A 301GLY A 298LEU A 297VAL A 293GLY A 70 | HEM A1002 (-4.4A)HEM A1002 (-3.4A)NoneNoneNone | 1.17A | 6gngA-6fwfA:undetectable | 6gngA-6fwfA:9.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gne | - (-) |
no annotation | 5 | GLY A 41LEU A 43VAL A 46ASP A 132ASN A 277 | ADP A 601 ( 3.8A)ACR A 602 ( 4.7A)ACR A 602 (-4.9A)NoneACR A 602 (-3.3A) | 0.84A | 6gngA-6gneA:42.2 | 6gngA-6gneA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gne | - (-) |
no annotation | 7 | GLY A 41LEU A 43VAL A 46ASP A 161ASN A 191ASN A 277GLN A 336 | ADP A 601 ( 3.8A)ACR A 602 ( 4.7A)ACR A 602 (-4.9A)ACR A 602 (-3.4A)ACR A 602 (-4.9A)ACR A 602 (-3.3A)ACR A 602 (-3.1A) | 0.53A | 6gngA-6gneA:42.2 | 6gngA-6gneA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gne | - (-) |
no annotation | 5 | GLY A 42LEU A 43ASP A 161ASN A 191GLN A 336 | ADP A 601 ( 3.2A)ACR A 602 ( 4.7A)ACR A 602 (-3.4A)ACR A 602 (-4.9A)ACR A 602 (-3.1A) | 0.91A | 6gngA-6gneA:42.2 | 6gngA-6gneA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gnf | - (-) |
no annotation | 6 | GLY A 19LEU A 20ASP A 151HIS A 153ASN A 182GLN A 342 | ADP A 601 ( 3.3A)QPS A 602 (-4.3A)QPS A 602 (-3.3A)QPS A 602 (-3.9A)QPS A 602 (-4.4A)QPS A 602 (-3.2A) | 0.88A | 6gngA-6gnfA:54.4 | 6gngA-6gnfA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gnf | - (-) |
no annotation | 10 | THR A 17GLY A 18LEU A 20VAL A 23ASP A 108ASP A 151HIS A 153ASN A 182ASN A 283GLN A 342 | QPS A 602 (-3.2A)ADP A 601 ( 3.8A)QPS A 602 (-4.3A)NoneQPS A 602 ( 2.5A)QPS A 602 (-3.3A)QPS A 602 (-3.9A)QPS A 602 (-4.4A)QPS A 602 (-3.4A)QPS A 602 (-3.2A) | 0.41A | 6gngA-6gnfA:54.4 | 6gngA-6gnfA:undetectable |