SIMILAR PATTERNS OF AMINO ACIDS FOR 6GBN_C_ADNC501_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bh6 | SUBTILISIN DY (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | GLN A 2THR A 3HIS A 67GLY A 83 | CA A 501 (-3.5A)NoneNoneNone | 1.19A | 6gbnC-1bh6A:4.7 | 6gbnC-1bh6A:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bxc | XYLOSE ISOMERASE (Thermuscaldophilus) |
PF01261(AP_endonuc_2) | 4 | GLN A 255THR A 16HIS A 284GLY A 247 | None | 1.21A | 6gbnC-1bxcA:2.2 | 6gbnC-1bxcA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c3l | SUBTILISIN-CARLSBERG (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | GLN A 2THR A 3HIS A 67GLY A 83 | CA A 282 (-3.3A)NoneNoneNone | 1.19A | 6gbnC-1c3lA:2.9 | 6gbnC-1c3lA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cfr | RESTRICTIONENDONUCLEASE (Citrobacterfreundii) |
PF07832(Bse634I) | 4 | GLN A 216THR A 221HIS A 182GLY A 226 | None | 1.08A | 6gbnC-1cfrA:undetectable | 6gbnC-1cfrA:24.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cjx | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Pseudomonasfluorescens) |
PF00903(Glyoxalase)PF14696(Glyoxalase_5) | 4 | GLN A 232THR A 163HIS A 240GLY A 317 | NoneACT A 631 ( 4.9A)FE2 A 629 (-3.3A)None | 1.22A | 6gbnC-1cjxA:undetectable | 6gbnC-1cjxA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddk | IMP-1 METALLOBETA-LACTAMASE (Pseudomonasaeruginosa) |
PF00753(Lactamase_B) | 4 | GLN A 212THR A 209THR A 140HIS A 77 | NoneNoneNone ZN A 500 (-3.4A) | 1.14A | 6gbnC-1ddkA:2.8 | 6gbnC-1ddkA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g3r | CELL DIVISIONINHIBITOR (Pyrococcusfuriosus) |
PF13614(AAA_31) | 4 | GLN A 77THR A 76THR A 20GLY A 210 | None | 1.00A | 6gbnC-1g3rA:2.8 | 6gbnC-1g3rA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hww | ALPHA-MANNOSIDASE II (Drosophilamelanogaster) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 4 | GLN A 249THR A 211THR A 806GLY A 402 | None | 1.22A | 6gbnC-1hwwA:undetectable | 6gbnC-1hwwA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ion | PROBABLE CELLDIVISION INHIBITORMIND (Pyrococcushorikoshii) |
PF13614(AAA_31) | 4 | GLN A 77THR A 76THR A 20GLY A 210 | None | 1.05A | 6gbnC-1ionA:undetectable | 6gbnC-1ionA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kg0 | GP42 PROTEIN (Humangammaherpesvirus4) |
no annotation | 4 | GLN C 219THR C 100THR C 104GLY C 113 | None | 0.93A | 6gbnC-1kg0C:undetectable | 6gbnC-1kg0C:16.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzh | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Aquifexaeolicus) |
PF01791(DeoC) | 4 | THR A 169THR A 215HIS A 220GLY A 161 | None | 1.17A | 6gbnC-1mzhA:2.8 | 6gbnC-1mzhA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pby | QUINOHEMOPROTEINAMINE DEHYDROGENASE60 KDA SUBUNIT (Paracoccusdenitrificans) |
PF09098(Dehyd-heme_bind)PF09099(Qn_am_d_aIII)PF09100(Qn_am_d_aIV)PF14930(Qn_am_d_aII) | 4 | GLN A 112THR A 66HIS A 62GLY A 35 | HEM A 992 (-3.1A)NoneNoneNone | 1.13A | 6gbnC-1pbyA:undetectable | 6gbnC-1pbyA:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q47 | SEMAPHORIN 3A (Mus musculus) |
PF01403(Sema) | 4 | GLN A 433THR A 432THR A 481GLY A 504 | None | 1.15A | 6gbnC-1q47A:undetectable | 6gbnC-1q47A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qqh | PAPILLOMAVIRUSTRANSCRIPTION FACTORE2 (Alphapapillomavirus7) |
PF00508(PPV_E2_N) | 4 | GLN A 115THR A 116THR A 104GLY A 113 | None | 1.21A | 6gbnC-1qqhA:undetectable | 6gbnC-1qqhA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s7s | H-2 CLASS IHISTOCOMPATIBILITYANTIGEN, K-B ALPHACHAIN (Mus musculus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 242THR A 233THR A 31GLY A 207 | None | 1.19A | 6gbnC-1s7sA:undetectable | 6gbnC-1s7sA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tuu | ACETATE KINASE (Methanosarcinathermophila) |
PF00871(Acetate_kinase) | 4 | THR A 329THR A 226HIS A 152GLY A 212 | NoneNoneNoneSO4 A 400 (-3.4A) | 1.15A | 6gbnC-1tuuA:undetectable | 6gbnC-1tuuA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 4 | GLN A 351THR A 329THR A 362GLY A 157 | None | 1.07A | 6gbnC-1u7gA:undetectable | 6gbnC-1u7gA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vpa | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATECYTIDYLYLTRANSFERASE (Thermotogamaritima) |
PF01128(IspD) | 4 | THR A 203THR A 157HIS A 101GLY A 10 | CTP A 500 ( 4.6A)NoneNoneCTP A 500 (-3.2A) | 1.20A | 6gbnC-1vpaA:2.3 | 6gbnC-1vpaA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zl6 | BOTULINUM NEUROTOXINTYPE E (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | THR A 231THR A 253HIS A 215GLY A 225 | NoneNone ZN A 422 ( 3.3A)None | 1.16A | 6gbnC-1zl6A:undetectable | 6gbnC-1zl6A:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c49 | SUGAR KINASE MJ0406 (Methanocaldococcusjannaschii) |
PF00294(PfkB) | 4 | THR A 214THR A 48HIS A 135GLY A 267 | ANP A1304 (-3.4A)NoneNoneNone | 1.19A | 6gbnC-2c49A:2.4 | 6gbnC-2c49A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2efl | FORMIN-BINDINGPROTEIN 1 (Homo sapiens) |
PF00611(FCH) | 4 | GLN A 214THR A 18HIS A 17GLY A 4 | None | 1.21A | 6gbnC-2eflA:undetectable | 6gbnC-2eflA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ice | COMPLEMENT C3 BETACHAIN (Homo sapiens) |
PF01835(A2M_N)PF07703(A2M_N_2) | 4 | GLN A 631THR A 632THR A 514HIS A 25 | None | 0.94A | 6gbnC-2iceA:undetectable | 6gbnC-2iceA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iir | ACETATE KINASE (Thermotogamaritima) |
PF00871(Acetate_kinase) | 4 | THR A 329THR A 225HIS A 151GLY A 211 | None | 1.12A | 6gbnC-2iirA:2.3 | 6gbnC-2iirA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ilx | 2',3'-CYCLIC-NUCLEOTIDE3'-PHOSPHODIESTERASE (Rattusnorvegicus) |
PF05881(CNPase) | 4 | THR A 164THR A 73HIS A 71GLY A 117 | None | 1.02A | 6gbnC-2ilxA:undetectable | 6gbnC-2ilxA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ip1 | TRYPTOPHANYL-TRNASYNTHETASE (Saccharomycescerevisiae) |
PF00579(tRNA-synt_1b) | 4 | THR A 116THR A 109HIS A 335GLY A 135 | None | 1.04A | 6gbnC-2ip1A:undetectable | 6gbnC-2ip1A:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nad | NAD-DEPENDENTFORMATEDEHYDROGENASE (Pseudomonas sp.101) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | THR A 220THR A 261HIS A 258GLY A 200 | NoneNAD A 394 (-4.4A)NAD A 394 (-4.4A)NAD A 394 (-3.4A) | 1.21A | 6gbnC-2nadA:5.6 | 6gbnC-2nadA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlz | CEPHALOSPORINACYLASE (Bacillushalodurans) |
PF01019(G_glu_transpept) | 4 | THR A 427THR A 78HIS A 83GLY A 424 | None | 1.21A | 6gbnC-2nlzA:undetectable | 6gbnC-2nlzA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvv | ACETYL-COAHYDROLASE/TRANSFERASE FAMILY PROTEIN (Porphyromonasgingivalis) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | GLN A 333THR A 107THR A 383HIS A 414 | GLN A 333 ( 0.6A)THR A 107 ( 0.8A)THR A 383 ( 0.8A)HIS A 414 ( 1.0A) | 1.02A | 6gbnC-2nvvA:undetectable | 6gbnC-2nvvA:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x98 | ALKALINE PHOSPHATASE (Halobacteriumsalinarum) |
PF00245(Alk_phosphatase) | 4 | GLN A 62THR A 166HIS A 170GLY A 307 | None MG A1477 ( 4.5A)PO4 A1474 (-4.5A)None | 1.17A | 6gbnC-2x98A:undetectable | 6gbnC-2x98A:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yew | E1 ENVELOPEGLYCOPROTEIN (Barmah Forestvirus) |
PF01589(Alpha_E1_glycop) | 4 | GLN B 204THR B 48THR B 53GLY B 195 | None | 1.11A | 6gbnC-2yewB:undetectable | 6gbnC-2yewB:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ak5 | HEMOGLOBIN-BINDINGPROTEASE HBP (Escherichiacoli) |
PF02395(Peptidase_S6) | 4 | GLN A 198THR A 197HIS A 125GLY A 194 | None | 1.17A | 6gbnC-3ak5A:undetectable | 6gbnC-3ak5A:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8p | CHAIN LENGTHDETERMINANT PROTEIN (Salmonellaenterica) |
PF02706(Wzz) | 4 | GLN A 145THR A 284THR A 120GLY A 143 | None | 1.09A | 6gbnC-3b8pA:undetectable | 6gbnC-3b8pA:19.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 73THR A 74THR A 219HIS A 363GLY A 415 | ADN A 500 (-3.6A)ADN A 500 (-4.5A)NAD A 550 ( 2.8A)ADN A 500 ( 3.7A)ADN A 500 ( 3.6A) | 0.19A | 6gbnC-3ce6A:55.7 | 6gbnC-3ce6A:54.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dci | ARYLESTERASE (Agrobacteriumfabrum) |
PF13472(Lipase_GDSL_2) | 4 | THR A 89THR A 193HIS A 23GLY A 8 | ACY A 220 ( 4.2A)NoneNoneNone | 1.15A | 6gbnC-3dciA:5.8 | 6gbnC-3dciA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dci | ARYLESTERASE (Agrobacteriumfabrum) |
PF13472(Lipase_GDSL_2) | 4 | THR A 89THR A 193HIS A 23GLY A 49 | ACY A 220 ( 4.2A)NoneNoneACY A 220 ( 3.8A) | 1.08A | 6gbnC-3dciA:5.8 | 6gbnC-3dciA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dyj | TALIN-1 (Mus musculus) |
no annotation | 4 | GLN A2077THR A2076THR A2140GLY A2065 | None | 1.19A | 6gbnC-3dyjA:undetectable | 6gbnC-3dyjA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e2d | ALKALINE PHOSPHATASE (Vibrio sp.G15-21) |
PF00245(Alk_phosphatase) | 4 | GLN A 18THR A 112HIS A 116GLY A 276 | None MG A 603 ( 4.8A)SO4 A 610 ( 4.8A)None | 1.22A | 6gbnC-3e2dA:undetectable | 6gbnC-3e2dA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fn9 | PUTATIVEBETA-GALACTOSIDASE (Bacteroidesfragilis) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 4 | GLN A 253THR A 254THR A 187GLY A 251 | None | 1.15A | 6gbnC-3fn9A:undetectable | 6gbnC-3fn9A:20.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156HIS A 300GLY A 351 | ADN A 438 (-3.8A)ADN A 438 (-4.6A)NAD A 439 ( 3.0A)ADN A 438 ( 4.0A)ADN A 438 ( 3.8A) | 0.19A | 6gbnC-3g1uA:60.1 | 6gbnC-3g1uA:63.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gfb | L-THREONINE3-DEHYDROGENASE (Thermococcuskodakarensis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 292THR A 93HIS A 67GLY A 155 | NAD A 500 (-3.6A)NoneNoneNone | 1.13A | 6gbnC-3gfbA:2.9 | 6gbnC-3gfbA:22.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 200HIS A 344GLY A 393 | RAB A 602 (-3.9A)RAB A 602 (-4.5A)NAD A 601 ( 2.9A)RAB A 602 ( 3.5A)RAB A 602 ( 3.8A) | 0.17A | 6gbnC-3glqA:58.4 | 6gbnC-3glqA:59.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156HIS A 300GLY A 351 | ADN A 439 (-3.6A)ADN A 439 (-4.7A)NAD A 438 (-3.8A)NoneADN A 439 (-3.5A) | 0.34A | 6gbnC-3h9uA:62.1 | 6gbnC-3h9uA:65.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hx6 | TYPE 4 FIMBRIALBIOGENESIS PROTEINPILY1 (Pseudomonasaeruginosa) |
PF05567(Neisseria_PilC) | 4 | GLN A1056THR A1057THR A1004GLY A1119 | None | 1.08A | 6gbnC-3hx6A:undetectable | 6gbnC-3hx6A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3l | ALKYLHALIDASE CMLS (Streptomycesvenezuelae) |
PF04820(Trp_halogenase) | 4 | THR A 21THR A 50HIS A 309GLY A 15 | None | 1.21A | 6gbnC-3i3lA:4.1 | 6gbnC-3i3lA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3izy | TRANSLATIONINITIATION FACTORIF-2, MITOCHONDRIAL (Bos taurus) |
PF00009(GTP_EFTU)PF11987(IF-2) | 4 | GLN P 215THR P 214THR P 252GLY P 218 | None | 1.22A | 6gbnC-3izyP:undetectable | 6gbnC-3izyP:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbl | NLR FAMILY CARDDOMAIN-CONTAININGPROTEIN 4 (Mus musculus) |
no annotation | 4 | THR K 281THR K 337HIS K 443GLY K 425 | None | 1.07A | 6gbnC-3jblK:undetectable | 6gbnC-3jblK:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3khy | PROPIONATE KINASE (Francisellatularensis) |
PF00871(Acetate_kinase) | 4 | THR A 320THR A 218HIS A 146GLY A 204 | None | 1.04A | 6gbnC-3khyA:undetectable | 6gbnC-3khyA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lkj | CD40 LIGAND (Homo sapiens) |
PF00229(TNF) | 4 | GLN A 160THR A 254HIS A 249GLY A 158 | None | 1.10A | 6gbnC-3lkjA:undetectable | 6gbnC-3lkjA:15.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 59THR A 60THR A 193HIS A 337GLY A 386 | K A 2 ( 3.3A)ADN A 500 (-4.6A)NAD A 550 ( 3.0A)ADN A 500 ( 3.6A)ADN A 500 (-3.7A) | 0.17A | 6gbnC-3n58A:59.3 | 6gbnC-3n58A:60.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ohn | OUTER MEMBRANE USHERPROTEIN FIMD (Escherichiacoli) |
PF00577(Usher) | 4 | GLN A 516THR A 314THR A 506GLY A 502 | None | 1.11A | 6gbnC-3ohnA:undetectable | 6gbnC-3ohnA:19.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 206HIS A 350GLY A 403 | ADE A 506 (-3.8A)ADE A 506 (-4.5A)NAD A 501 (-2.8A)NoneADE A 506 ( 3.6A) | 0.15A | 6gbnC-3oneA:55.4 | 6gbnC-3oneA:58.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pxn | KINESIN-LIKE PROTEINNOD (Drosophilamelanogaster) |
PF00225(Kinesin) | 4 | THR A 286THR A 210HIS A 212GLY A 78 | None | 1.13A | 6gbnC-3pxnA:undetectable | 6gbnC-3pxnA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slc | ACETATE KINASE (Salmonellaenterica) |
PF00871(Acetate_kinase) | 4 | THR A 331THR A 228HIS A 154GLY A 214 | None | 1.08A | 6gbnC-3slcA:undetectable | 6gbnC-3slcA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uxf | FIMBRIAL SUBUNITTYPE 1 (Actinomycesoris) |
no annotation | 4 | GLN A 55THR A 56THR A 148GLY A 187 | None | 1.23A | 6gbnC-3uxfA:undetectable | 6gbnC-3uxfA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9r | ABSCISIC ACIDRECEPTOR PYL9 (Arabidopsisthaliana) |
PF10604(Polyketide_cyc2) | 4 | THR A 127THR A 35HIS A 25GLY A 14 | None | 1.16A | 6gbnC-3w9rA:undetectable | 6gbnC-3w9rA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbh | ALKALINE PHOSPHATASE (Halomonas sp.#593) |
PF00245(Alk_phosphatase) | 4 | GLN A 18THR A 112HIS A 116GLY A 272 | None MG A 501 ( 4.8A)NoneNone | 1.21A | 6gbnC-3wbhA:undetectable | 6gbnC-3wbhA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zi5 | RESTRICTIONENDONUCLEASE (Bacillus firmus) |
no annotation | 4 | GLN A 223THR A 219THR A 293GLY A 224 | None | 1.12A | 6gbnC-3zi5A:undetectable | 6gbnC-3zi5A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4axv | MPAA (Vibriocampbellii) |
PF04952(AstE_AspA) | 4 | THR A 102THR A 47HIS A 48GLY A 128 | NoneNone ZN A 301 (-3.2A)None | 1.10A | 6gbnC-4axvA:undetectable | 6gbnC-4axvA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bgu | MALATE DEHYDROGENASE (Haloferaxvolcanii) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLN A 45THR A 42THR A 69GLY A 14 | None | 1.14A | 6gbnC-4bguA:6.3 | 6gbnC-4bguA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccd | GALACTOCEREBROSIDASE (Mus musculus) |
PF02057(Glyco_hydro_59)PF17387(Glyco_hydro_59M) | 4 | GLN A 391THR A 449HIS A 330GLY A 352 | None | 1.05A | 6gbnC-4ccdA:undetectable | 6gbnC-4ccdA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnk | L-AMINO ACID OXIDASE (Streptococcuscristatus) |
PF03486(HI0933_like) | 4 | GLN A 156THR A 6THR A 348HIS A 389 | None | 1.17A | 6gbnC-4cnkA:2.1 | 6gbnC-4cnkA:23.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2c | CHIMERIC WZZB CHAINLENGTH DETERMINANTPROTEIN (Salmonellaenterica;Shigellaflexneri) |
no annotation | 4 | GLN A 145THR A 284THR A 120GLY A 143 | None | 1.11A | 6gbnC-4e2cA:undetectable | 6gbnC-4e2cA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwm | PROPIONATE KINASE (Salmonellaenterica) |
PF00871(Acetate_kinase) | 4 | THR A 324THR A 221HIS A 147GLY A 207 | NoneNoneNoneATP A 405 ( 3.4A) | 1.08A | 6gbnC-4fwmA:2.4 | 6gbnC-4fwmA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h0o | ACETATE KINASE (Entamoebahistolytica) |
PF00871(Acetate_kinase) | 4 | THR A 321THR A 217HIS A 146GLY A 203 | None | 1.18A | 6gbnC-4h0oA:undetectable | 6gbnC-4h0oA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hst | GLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE BETA CHAIN (Pseudomonas) |
PF01804(Penicil_amidase) | 4 | THR B 162THR B 170HIS B 224GLY B 190 | None | 1.22A | 6gbnC-4hstB:undetectable | 6gbnC-4hstB:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k11 | PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC (Homo sapiens) |
PF00017(SH2)PF00018(SH3_1)PF07714(Pkinase_Tyr) | 4 | GLN A 251THR A 252THR A 289GLY A 338 | NoneNoneNone0J9 A 601 (-4.0A) | 1.14A | 6gbnC-4k11A:undetectable | 6gbnC-4k11A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4loa | DE-NOVO DESIGNAMIDASE (syntheticconstruct) |
PF01202(SKI) | 4 | THR A 80THR A 134HIS A 130GLY A 14 | NoneNoneNone CL A 201 ( 4.7A) | 1.12A | 6gbnC-4loaA:undetectable | 6gbnC-4loaA:16.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lvc | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE(SAHASE) (Bradyrhizobiumelkanii) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 62THR A 63THR A 198HIS A 342GLY A 391 | NH4 A 502 ( 3.1A)ADN A 501 (-4.5A)NAD A 503 ( 2.9A)ADN A 501 ( 3.7A)ADN A 501 (-3.6A) | 0.10A | 6gbnC-4lvcA:58.5 | 6gbnC-4lvcA:60.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n4r | LPS-ASSEMBLY PROTEINLPTD (Salmonellaenterica) |
PF04453(OstA_C) | 4 | GLN A 583THR A 561THR A 547GLY A 606 | None | 1.21A | 6gbnC-4n4rA:undetectable | 6gbnC-4n4rA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nar | PUTATIVE URONATEISOMERASE (Thermotogamaritima) |
PF09861(DUF2088) | 4 | THR A 157THR A 284HIS A 73GLY A 150 | NoneNoneSO4 A 501 (-4.6A)ACT A 504 (-4.2A) | 1.15A | 6gbnC-4narA:2.6 | 6gbnC-4narA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubq | BETA-LACTAMASE (Acinetobacterbaumannii) |
no annotation | 4 | GLN A 213THR A 210THR A 141HIS A 78 | NoneNoneNone ZN A 301 (-3.4A) | 1.16A | 6gbnC-4ubqA:undetectable | 6gbnC-4ubqA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4j | PUTATIVE OXYGENASE (Amycolatopsisorientalis) |
PF01494(FAD_binding_3) | 4 | THR A 47THR A 333HIS A 280GLY A 43 | NoneNoneNoneFAD A 503 (-3.2A) | 0.96A | 6gbnC-4x4jA:3.0 | 6gbnC-4x4jA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xjx | HSDR (Escherichiacoli) |
PF04313(HSDR_N)PF04851(ResIII)PF12008(EcoR124_C) | 4 | THR A 346THR A 661HIS A 411GLY A 360 | None | 1.08A | 6gbnC-4xjxA:2.7 | 6gbnC-4xjxA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgv | FERREDOXIN RECEPTOR (Pectobacteriumatrosepticum) |
PF07715(Plug) | 4 | THR A 633THR A 670HIS A 119GLY A 561 | None | 1.11A | 6gbnC-4zgvA:undetectable | 6gbnC-4zgvA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zud | CHIMERA PROTEIN OFSOLUBLE CYTOCHROMEB562 AND TYPE-1ANGIOTENSIN IIRECEPTOR (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 4 | THR A 88THR A 287HIS A 256GLY A 22 | OLM A1201 ( 4.6A)NoneNoneNone | 1.21A | 6gbnC-4zudA:undetectable | 6gbnC-4zudA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ams | RIBOSOME ASSEMBLYPROTEIN SQT1 (Saccharomycescerevisiae) |
no annotation | 4 | GLN A 144THR A 93HIS A 95GLY A 141 | None | 1.09A | 6gbnC-5amsA:undetectable | 6gbnC-5amsA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3r | IMP-18 (Pseudomonasaeruginosa) |
no annotation | 4 | GLN A 230THR A 227THR A 158HIS A 95 | NoneNoneNone ZN A2001 ( 3.4A) | 1.17A | 6gbnC-5b3rA:2.7 | 6gbnC-5b3rA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6o | HOMOSERINEO-ACETYLTRANSFERASE (Corynebacteriumglutamicum) |
PF00561(Abhydrolase_1) | 4 | GLN A 88THR A 56THR A 17GLY A 90 | None | 1.03A | 6gbnC-5d6oA:4.8 | 6gbnC-5d6oA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eue | PUTATIVESPHINGOSINE-1-PHOSPHATE LYASE (Symbiobacteriumthermophilum) |
PF00282(Pyridoxal_deC) | 4 | GLN A 333THR A 349THR A 309GLY A 162 | None | 1.21A | 6gbnC-5eueA:2.5 | 6gbnC-5eueA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffn | ENZYME SUBTILASESUBTY FROM BACILLUSSP. TY145 (Bacillus sp.(in: Bacteria)) |
PF00082(Peptidase_S8) | 4 | GLN A 6THR A 5HIS A 75GLY A 84 | None | 1.18A | 6gbnC-5ffnA:3.3 | 6gbnC-5ffnA:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h0k | UNCHARACTERIZEDPROTEIN (Pedobacterheparinus) |
PF16265(DUF4918) | 4 | GLN A 37THR A 72THR A 84GLY A 92 | None | 1.18A | 6gbnC-5h0kA:undetectable | 6gbnC-5h0kA:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i68 | ALCOHOL OXIDASE 1 (Komagataellapastoris) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | THR A 270THR A 565HIS A 309GLY A 427 | None | 1.07A | 6gbnC-5i68A:undetectable | 6gbnC-5i68A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k0w | CLASS BCARBAPENEMASE GOB-18 (Elizabethkingiameningoseptica) |
PF00753(Lactamase_B) | 4 | THR A 144THR A 176HIS A 175GLY A 69 | NoneNone ZN A 302 (-3.3A)None | 1.06A | 6gbnC-5k0wA:undetectable | 6gbnC-5k0wA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5z | PARA (Sulfolobus sp.NOB8H2) |
PF13614(AAA_31) | 4 | THR A 206THR A 142HIS A 9GLY A 202 | None | 1.20A | 6gbnC-5k5zA:3.7 | 6gbnC-5k5zA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o8f | GAMMA-AMINOBUTYRICACID RECEPTORSUBUNITBETA-3,GAMMA-AMINOBUTYRIC ACID RECEPTORSUBUNITALPHA-5,GAMMA-AMINOBUTYRIC ACID RECEPTORSUBUNIT ALPHA-5 (Homo sapiens) |
no annotation | 4 | GLN A 65THR A 60HIS A 107GLY A 127 | None | 1.23A | 6gbnC-5o8fA:undetectable | 6gbnC-5o8fA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT BTUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDD (Methanothermobactersp. CaT2;Methanothermobacterwolfeii) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | THR B 372THR B 114HIS B 290GLY D 81 | NoneMGD B 503 ( 3.9A)MGD B 504 (-3.5A)None | 1.09A | 6gbnC-5t5iB:undetectable | 6gbnC-5t5iB:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u5i | HTPA REDUCTASE (Selaginellamoellendorffii) |
no annotation | 4 | GLN A 172THR A 181HIS A 244GLY A 223 | None | 1.22A | 6gbnC-5u5iA:8.2 | 6gbnC-5u5iA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uc7 | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE (environmentalsamples) |
PF00202(Aminotran_3) | 4 | GLN A 179THR A 139HIS A 145GLY A 219 | None | 1.11A | 6gbnC-5uc7A:undetectable | 6gbnC-5uc7A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xh9 | EXTRACELLULARINVERTASE (Aspergilluskawachii) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | THR A 253THR A 307HIS A 147GLY A 220 | None | 1.16A | 6gbnC-5xh9A:undetectable | 6gbnC-5xh9A:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xii | PROLYL-TRNASYNTHETASE (PRORS) (Toxoplasmagondii) |
no annotation | 4 | GLN A 586THR A 492THR A 541GLY A 563 | None | 1.06A | 6gbnC-5xiiA:2.7 | 6gbnC-5xiiA:11.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xip | PROLYL-TRNASYNTHETASE, PUTATIVE (Eimeria tenella) |
no annotation | 4 | GLN A 506THR A 412THR A 461GLY A 483 | None | 1.21A | 6gbnC-5xipA:undetectable | 6gbnC-5xipA:10.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xtd | NADH DEHYDROGENASE[UBIQUINONE] 1 ALPHASUBCOMPLEX SUBUNIT9, MITOCHONDRIAL (Homo sapiens) |
PF01370(Epimerase) | 4 | GLN J 341THR J 343HIS J 72GLY J 339 | None | 1.15A | 6gbnC-5xtdJ:undetectable | 6gbnC-5xtdJ:23.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 62THR A 63THR A 162HIS A 306GLY A 357 | ADN A 501 (-3.8A)ADN A 501 (-4.5A)NAD A 500 ( 2.9A)ADN A 501 ( 3.7A)ADN A 501 (-3.6A) | 0.11A | 6gbnC-6aphA:66.5 | 6gbnC-6aphA:77.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6l | V-TYPE PROTON ATPASESUBUNIT A, VACUOLARISOFORM (Saccharomycescerevisiae) |
no annotation | 4 | GLN A 35THR A 32THR A 348GLY A 96 | None | 1.19A | 6gbnC-6c6lA:undetectable | 6gbnC-6c6lA:9.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6con | COA-TRANSFERASESUBUNIT BETA (Mycobacteriumtuberculosis) |
no annotation | 4 | GLN B 222THR B 223HIS B 141GLY B 200 | None | 1.19A | 6gbnC-6conB:2.8 | 6gbnC-6conB:11.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dw1 | - (-) |
no annotation | 4 | GLN E 65THR E 60HIS E 107GLY E 127 | None | 1.15A | 6gbnC-6dw1E:undetectable | 6gbnC-6dw1E:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eub | ANGIOPOIETIN-RELATEDPROTEIN 4 (Homo sapiens) |
no annotation | 4 | THR A 393THR A 382HIS A 356GLY A 377 | NoneNone1PE A 501 ( 4.3A)None | 1.21A | 6gbnC-6eubA:undetectable | 6gbnC-6eubA:10.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | GLN B 65THR B 66THR B 165HIS B 323GLY B 381 | K B 504 ( 3.0A)ADN B 502 (-4.6A)NAD B 501 ( 2.8A) ZN B 505 (-3.2A)ADN B 502 ( 3.7A) | 0.16A | 6gbnC-6f3mB:57.6 | 6gbnC-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f8z | ALPHA-1,2-MANNOSIDASE, PUTATIVE (Bacteroidesthetaiotaomicron) |
no annotation | 4 | GLN A 318THR A 315HIS A 592GLY A 90 | None | 1.05A | 6gbnC-6f8zA:undetectable | 6gbnC-6f8zA:10.92 |