SIMILAR PATTERNS OF AMINO ACIDS FOR 6G2P_A_TRPA502_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c9k ADENOSYLCOBINAMIDE
KINASE

(Salmonella
enterica) 		PF02283
(CobU) 		4 HIS A  15
LEU A  78
VAL A 130
TRP A 169
 None
 1.26A 6g2pA-1c9kA:
undetectable		 6g2pA-1c9kA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgp ARISTOLOCHENE
SYNTHASE

(Penicillium
roqueforti) 		no annotation 4 ARG A 132
LEU A 113
TYR A 129
VAL A 110
 None
 1.28A 6g2pA-1dgpA:
undetectable		 6g2pA-1dgpA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1h BOTULINUM NEUROTOXIN
TYPE A LIGHT CHAIN

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 ARG B 263
TYR B 285
LEU B 283
TYR B 341
 None
 1.24A 6g2pA-1e1hB:
undetectable		 6g2pA-1e1hB:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I GAMMA
SUBUNIT

(Methanopyrus
kandleri) 		PF02240
(MCR_gamma) 		4 ARG C 107
LEU C 235
TYR C   9
VAL C 238
 None
 1.32A 6g2pA-1e6vC:
undetectable		 6g2pA-1e6vC:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ea9 CYCLOMALTODEXTRINASE

(Bacillus sp.
(in: Bacteria)) 		PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C) 		4 HIS C 180
LEU C 460
TYR C 134
VAL C 458
 None
 1.25A 6g2pA-1ea9C:
undetectable		 6g2pA-1ea9C:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8r L-AMINO ACID OXIDASE

(Calloselasma
rhodostoma) 		PF01593
(Amino_oxidase) 		4 ARG A  71
LEU A 316
TYR A 321
VAL A 299
 FAD  A 527 (-4.0A)
None
None
None
 0.96A 6g2pA-1f8rA:
31.9		 6g2pA-1f8rA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9x M32 CARBOXYPEPTIDASE

(Pyrococcus
furiosus) 		PF02074
(Peptidase_M32) 		4 TYR A 276
HIS A 298
LEU A 278
VAL A 249
 None
 1.22A 6g2pA-1k9xA:
undetectable		 6g2pA-1k9xA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqo NICOTINAMIDE
MONONUCLEOTIDE
ADENYLYL TRANSFERASE

(Homo sapiens) 		PF01467
(CTP_transf_like) 		5 ARG A  40
TYR A  34
HIS A 211
LEU A  11
VAL A   9
 None
 1.43A 6g2pA-1kqoA:
undetectable		 6g2pA-1kqoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ojz ADP-RIBOSYLTRANSFERA
SE

(Staphylococcus
aureus) 		PF03496
(ADPrib_exo_Tox) 		4 TYR A  91
LEU A 122
TYR A 131
VAL A 194
 None
 1.35A 6g2pA-1ojzA:
undetectable		 6g2pA-1ojzA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uik ALPHA PRIME SUBUNIT
OF BETA-CONGLYCININ

(Glycine max) 		PF00190
(Cupin_1) 		4 TYR A 247
HIS A 203
TYR A 209
VAL A 168
 None
 1.29A 6g2pA-1uikA:
undetectable		 6g2pA-1uikA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Salmonella
enterica) 		PF00483
(NTP_transferase) 		4 TYR A  65
LEU A  99
VAL A  97
TRP A  95
 None
 1.33A 6g2pA-1wvcA:
undetectable		 6g2pA-1wvcA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwe COMPLEMENT C5

(Homo sapiens) 		PF01759
(NTR) 		4 TYR A1541
LEU A1563
TYR A1619
VAL A1545
 None
 1.24A 6g2pA-1xweA:
undetectable		 6g2pA-1xweA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE, A
SUBUNIT
PARTICULATE METHANE
MONOOXYGENASE
SUBUNIT C2

(Methylococcus
capsulatus;
Methylococcus
capsulatus) 		PF02461
(AMO)
PF04896
(AmoC) 		4 TYR B  83
LEU B  26
TYR C 246
VAL B  29
 None
 1.16A 6g2pA-1yewB:
undetectable		 6g2pA-1yewB:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yis ADENYLOSUCCINATE
LYASE

(Caenorhabditis
elegans) 		PF00206
(Lyase_1) 		4 ARG A 333
TYR A 120
LEU A 251
VAL A 248
 None
 1.38A 6g2pA-1yisA:
undetectable		 6g2pA-1yisA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yq2 BETA-GALACTOSIDASE

(Arthrobacter
sp. C2-2) 		PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 ARG A  42
TYR A  71
LEU A 183
VAL A 185
 None
 1.40A 6g2pA-1yq2A:
undetectable		 6g2pA-1yq2A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z26 ARGONAUTE

(Pyrococcus
furiosus) 		PF02171
(Piwi)
PF12212
(PAZ_siRNAbind) 		4 TYR A 272
HIS A 173
LEU A 155
TYR A 122
 None
 1.40A 6g2pA-1z26A:
undetectable		 6g2pA-1z26A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7n PROBABLE
NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Helicobacter
pylori) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 TYR A 222
LEU A 232
TYR A 227
VAL A 206
 None
 1.32A 6g2pA-2b7nA:
undetectable		 6g2pA-2b7nA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bvg 6-HYDROXY-D-NICOTINE
OXIDASE

(Paenarthrobacter
nicotinovorans) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 ARG A 104
TYR A 172
LEU A 163
VAL A 195
 None
None
None
FAD  A 600 (-3.9A)
 1.02A 6g2pA-2bvgA:
undetectable		 6g2pA-2bvgA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyc TYROSYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00579
(tRNA-synt_1b) 		4 TYR A  97
LEU A  83
TYR A  45
VAL A 371
 None
 1.36A 6g2pA-2cycA:
1.2		 6g2pA-2cycA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d28 TYPE II SECRETION
ATPASE XPSE

(Xanthomonas
campestris) 		PF05157
(T2SSE_N) 		4 ARG C 137
TYR C 114
LEU C  64
VAL C 134
 None
 1.36A 6g2pA-2d28C:
undetectable		 6g2pA-2d28C:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ffj CONSERVED
HYPOTHETICAL PROTEIN

(Archaeoglobus
fulgidus) 		PF01937
(DUF89) 		4 ARG A  14
LEU A  65
TYR A  71
VAL A  61
 SO4  A 290 (-2.7A)
None
SO4  A 290 ( 4.9A)
None
 1.21A 6g2pA-2ffjA:
2.2		 6g2pA-2ffjA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjs USG-1 PROTEIN
HOMOLOG

(Pseudomonas
aeruginosa) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 TYR A 335
HIS A 334
LEU A 327
VAL A 110
 None
 1.30A 6g2pA-2hjsA:
5.0		 6g2pA-2hjsA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3e G-RICH

(Carassius
auratus) 		PF05881
(CNPase) 		4 TYR A 196
HIS A  42
LEU A 194
VAL A 187
 None
 1.23A 6g2pA-2i3eA:
undetectable		 6g2pA-2i3eA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jh3 RIBOSOMAL PROTEIN
S2-RELATED PROTEIN

(Deinococcus
radiodurans) 		PF01903
(CbiX) 		4 ARG A 263
LEU A   6
TYR A  39
VAL A  68
 None
 1.13A 6g2pA-2jh3A:
undetectable		 6g2pA-2jh3A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jtf PHD FINGER PROTEIN
20-LIKE 1

(Homo sapiens) 		PF02820
(MBT) 		4 ARG A  64
LEU A  44
VAL A  45
TRP A  50
 None
 1.38A 6g2pA-2jtfA:
undetectable		 6g2pA-2jtfA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbr URIDINE
DIPHOSPHO-N-ACETYLEN
OLPYRUVYLGLUCOSAMINE
REDUCTASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 ARG A  66
LEU A  44
VAL A  62
TRP A   8
 None
FAD  A 401 (-4.5A)
None
None
 0.89A 6g2pA-2mbrA:
undetectable		 6g2pA-2mbrA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfx UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN

(Ruegeria sp.
TM1040) 		PF02627
(CMD) 		4 HIS A  92
LEU A  40
TYR A 185
VAL A  39
 None
 0.96A 6g2pA-2pfxA:
undetectable		 6g2pA-2pfxA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyx TRYPTOPHAN
HALOGENASE

(Shewanella
frigidimarina) 		PF04820
(Trp_halogenase) 		4 TYR A 169
LEU A 514
TYR A 167
VAL A 517
 None
 1.23A 6g2pA-2pyxA:
10.2		 6g2pA-2pyxA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhg CELLULOSE-BINDING
PROTEIN

(Saccharophagus
degradans) 		PF07632
(DUF1593) 		4 ARG A 545
TYR A 715
HIS A 808
TRP A 709
 None
 1.24A 6g2pA-2yhgA:
undetectable		 6g2pA-2yhgA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yx0 RADICAL SAM ENZYME

(Pyrococcus
horikoshii) 		PF04055
(Radical_SAM)
PF08608
(Wyosine_form) 		4 ARG A 265
LEU A 243
TYR A 309
VAL A 241
 None
 1.27A 6g2pA-2yx0A:
undetectable		 6g2pA-2yx0A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zm2 6-AMINOHEXANOATE-DIM
ER HYDROLASE

(Flavobacterium
sp.) 		PF00144
(Beta-lactamase) 		4 TYR A 198
HIS A   9
LEU A 144
VAL A 141
 None
 1.26A 6g2pA-2zm2A:
undetectable		 6g2pA-2zm2A:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b0h NITRITE REDUCTASE

(Nicotiana
tabacum) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 LEU A 276
TYR A 246
VAL A 261
TRP A 225
 None
 1.28A 6g2pA-3b0hA:
undetectable		 6g2pA-3b0hA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjr PUTATIVE
CARBOXYLESTERASE

(Lactobacillus
plantarum) 		PF07859
(Abhydrolase_3) 		4 HIS A 117
LEU A  80
TYR A  42
VAL A  83
 None
 1.18A 6g2pA-3bjrA:
undetectable		 6g2pA-3bjrA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1l PUTATIVE ANTIOXIDANT
DEFENSE PROTEIN
MLR4105

(Mesorhizobium
japonicum) 		PF02627
(CMD) 		4 HIS A  89
LEU A  37
TYR A 182
VAL A  36
 PEG  A 188 (-4.4A)
PEG  A 190 ( 4.9A)
None
PEG  A 188 ( 4.5A)
 1.04A 6g2pA-3c1lA:
undetectable		 6g2pA-3c1lA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		4 ARG A 310
TYR A 157
LEU A 144
TYR A  83
 AVD  A 833 (-4.0A)
None
None
None
 1.36A 6g2pA-3cemA:
2.7		 6g2pA-3cemA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dse BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 ARG A 264
TYR A 286
LEU A 284
TYR A 342
 None
 1.39A 6g2pA-3dseA:
undetectable		 6g2pA-3dseA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzc UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Vibrio cholerae) 		PF02350
(Epimerase_2) 		4 ARG A  41
HIS A  40
LEU A  68
VAL A  71
 None
 1.12A 6g2pA-3dzcA:
undetectable		 6g2pA-3dzcA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g8a RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G

(Thermus
thermophilus) 		PF02527
(GidB) 		4 ARG A 133
TYR A 152
HIS A 148
LEU A  87
 None
 1.29A 6g2pA-3g8aA:
2.1		 6g2pA-3g8aA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hs0 COBRA VENOM FACTOR

(Naja kaouthia) 		PF01759
(NTR)
PF07677
(A2M_recep) 		4 ARG C1587
HIS C1590
LEU C1507
TYR C1559
 None
 1.27A 6g2pA-3hs0C:
undetectable		 6g2pA-3hs0C:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF10

(Schizosaccharomyces
pombe) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF03764
(EFG_IV)
PF16004
(EFTUD2) 		4 TYR B 589
LEU B 524
TYR B 465
VAL B 580
 None
 1.33A 6g2pA-3jb9B:
undetectable		 6g2pA-3jb9B:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2w BETAINE-ALDEHYDE
DEHYDROGENASE

(Pseudoalteromonas
atlantica) 		PF00171
(Aldedh) 		4 HIS A 345
LEU A 377
TYR A 372
VAL A 354
 None
 1.35A 6g2pA-3k2wA:
undetectable		 6g2pA-3k2wA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kez PUTATIVE SUGAR
BINDING PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ARG A 357
LEU A 327
TYR A 260
VAL A 337
 None
 1.02A 6g2pA-3kezA:
undetectable		 6g2pA-3kezA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ks4 POLYMERASE COFACTOR
VP35

(Reston
ebolavirus) 		PF02097
(Filo_VP35) 		4 ARG A 301
LEU A 231
VAL A 314
TRP A 313
 None
 1.28A 6g2pA-3ks4A:
undetectable		 6g2pA-3ks4A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7g XAA-PRO DIPEPTIDASE

(Alteromonas sp.) 		PF00557
(Peptidase_M24) 		4 TYR A 128
HIS A  34
LEU A 119
VAL A 115
 None
 1.18A 6g2pA-3l7gA:
undetectable		 6g2pA-3l7gA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxu TRIPEPTIDYL-PEPTIDAS
E 2

(Drosophila
melanogaster) 		PF00082
(Peptidase_S8)
PF12580
(TPPII)
PF12583
(TPPII_N) 		4 ARG X 333
TYR X 486
LEU X 475
VAL X 472
 None
 1.32A 6g2pA-3lxuX:
undetectable		 6g2pA-3lxuX:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m4x NOL1/NOP2/SUN FAMILY
PROTEIN

(Enterococcus
faecium) 		PF01189
(Methyltr_RsmB-F)
PF13636
(Methyltranf_PUA)
PF17125
(Methyltr_RsmF_N)
PF17126
(RsmF_methylt_CI) 		4 LEU A 401
TYR A 411
VAL A 426
TRP A 425
 None
 1.38A 6g2pA-3m4xA:
1.8		 6g2pA-3m4xA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbr GLUTAMINE
CYCLOTRANSFERASE

(Xanthomonas
campestris) 		PF05096
(Glu_cyclase_2) 		4 TYR X 139
LEU X 131
VAL X  92
TRP X  94
 None
 1.09A 6g2pA-3mbrX:
undetectable		 6g2pA-3mbrX:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3px2 N-METHYLTRANSFERASE

(Streptomyces
fradiae) 		PF13649
(Methyltransf_25) 		4 TYR A  22
HIS A  26
TYR A  14
VAL A 192
 SAH  A 263 (-4.6A)
T3Q  A 301 (-4.1A)
SAH  A 263 ( 3.9A)
None
 1.00A 6g2pA-3px2A:
undetectable		 6g2pA-3px2A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2h A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 1

(Homo sapiens) 		PF01421
(Reprolysin) 		4 HIS A  87
LEU A 103
TYR A  98
VAL A  13
 MG  A 610 (-3.7A)
None
None
None
 1.33A 6g2pA-3q2hA:
undetectable		 6g2pA-3q2hA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rva ORGANOPHOSPHORUS
ACID ANHYDROLASE

(Alteromonas
macleodii) 		PF00557
(Peptidase_M24) 		4 TYR A 128
HIS A  34
LEU A 119
VAL A 115
 None
 1.14A 6g2pA-3rvaA:
undetectable		 6g2pA-3rvaA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wd8 TYPE III POLYKETIDE
SYNTHASE QUINOLONE
SYNTHASE

(Citrus x
microcarpa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 TYR A  40
LEU A  77
TYR A  36
VAL A  72
 None
 1.32A 6g2pA-3wd8A:
undetectable		 6g2pA-3wd8A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wy2 ALPHA-GLUCOSIDASE

(Halomonas sp.
H11) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 TYR A  14
LEU A 453
TYR A  41
VAL A 449
 None
 0.78A 6g2pA-3wy2A:
undetectable		 6g2pA-3wy2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23

(Clostridium
botulinum;
Homo sapiens) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		4 ARG A 264
TYR A 286
LEU A 284
TYR A 342
 None
 1.29A 6g2pA-3zusA:
undetectable		 6g2pA-3zusA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b4o EPIMERASE FAMILY
PROTEIN SDR39U1

(Homo sapiens) 		PF01370
(Epimerase)
PF08338
(DUF1731) 		4 TYR A 277
LEU A 215
TYR A 279
VAL A 155
 None
 1.18A 6g2pA-4b4oA:
2.3		 6g2pA-4b4oA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqi ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC

(Arabidopsis
thaliana) 		PF00343
(Phosphorylase) 		4 ARG A 315
TYR A 160
LEU A 147
TYR A  86
 None
 1.33A 6g2pA-4bqiA:
0.7		 6g2pA-4bqiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fc2 POLY(ADP-RIBOSE)
GLYCOHYDROLASE

(Mus musculus) 		PF05028
(PARG_cat) 		4 TYR A 950
LEU A 924
TYR A 946
VAL A 921
 None
 1.07A 6g2pA-4fc2A:
undetectable		 6g2pA-4fc2A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fg8 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 ARG A  41
TYR A  85
LEU A  93
TYR A  20
 None
 1.40A 6g2pA-4fg8A:
undetectable		 6g2pA-4fg8A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g34 EUKARYOTIC
TRANSLATION
INITIATION FACTOR
2-ALPHA KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 ARG A1026
TYR A 989
LEU A1057
VAL A1033
 None
 1.35A 6g2pA-4g34A:
undetectable		 6g2pA-4g34A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gha POLYMERASE COFACTOR
VP35

(Marburg
marburgvirus) 		PF02097
(Filo_VP35) 		4 ARG A 301
LEU A 231
VAL A 314
TRP A 313
 U  I   2 ( 4.5A)
None
None
None
 1.05A 6g2pA-4ghaA:
undetectable		 6g2pA-4ghaA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gn1 RAS-ASSOCIATED AND
PLECKSTRIN HOMOLOGY
DOMAINS-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00169
(PH)
PF00788
(RA) 		4 ARG A 501
LEU A 297
TYR A 357
VAL A 293
 None
 1.29A 6g2pA-4gn1A:
undetectable		 6g2pA-4gn1A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hh2 TRANSCRIPTIONAL
REGULATOR, PPSR

(Rhodobacter
sphaeroides) 		PF13188
(PAS_8)
PF13426
(PAS_9) 		4 TYR A 102
HIS A  90
VAL A  35
TRP A  53
 None
 1.22A 6g2pA-4hh2A:
undetectable		 6g2pA-4hh2A:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpk COLLAGENASE

(Hathewaya
histolytica) 		PF04151
(PPC) 		4 TYR A 994
LEU A 946
TYR A 996
VAL A 978
 None
 1.24A 6g2pA-4hpkA:
undetectable		 6g2pA-4hpkA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lir NUCLEOPORIN NUP53

(Homo sapiens) 		PF05172
(Nup35_RRM) 		4 TYR A 215
LEU A 225
TYR A 196
VAL A 240
 None
 1.31A 6g2pA-4lirA:
undetectable		 6g2pA-4lirA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbg CAAX
FARNESYLTRANSFERASE
BETA SUBUNIT RAM1

(Aspergillus
fumigatus) 		PF00432
(Prenyltrans) 		4 TYR B 436
HIS B 370
LEU B 164
TYR B 156
 None
 1.13A 6g2pA-4mbgB:
undetectable		 6g2pA-4mbgB:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfz DBV8 PROTEIN

(Nonomuraea
gerenzanensis) 		no annotation 4 TYR A 113
LEU A 143
TYR A 109
VAL A  50
 None
 1.37A 6g2pA-4mfzA:
undetectable		 6g2pA-4mfzA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nz5 DEACETYLASE DA1

(Vibrio cholerae) 		PF01522
(Polysacc_deac_1) 		4 TYR A 335
HIS A 227
LEU A 352
VAL A 357
 None
 1.35A 6g2pA-4nz5A:
2.5		 6g2pA-4nz5A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onq DNA
METHYLTRANSFERASE

(Nicotiana
tabacum) 		PF00145
(DNA_methylase) 		4 TYR A 292
HIS A 335
LEU A 474
VAL A 473
 None
 0.98A 6g2pA-4onqA:
undetectable		 6g2pA-4onqA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onz PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
ovatus) 		PF04041
(Glyco_hydro_130) 		4 ARG A 259
TYR A 285
LEU A 310
VAL A 318
 None
 1.18A 6g2pA-4onzA:
undetectable		 6g2pA-4onzA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oz5 BACILLUS SUBTILIS
HMOB

(Bacillus
subtilis) 		PF03992
(ABM) 		4 TYR A 162
LEU A 116
TYR A   7
VAL A 114
 None
 1.28A 6g2pA-4oz5A:
undetectable		 6g2pA-4oz5A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pv4 PROLINE
AMINOPEPTIDASE P II

(Yersinia pestis) 		PF00557
(Peptidase_M24)
PF05195
(AMP_N) 		4 ARG A   9
TYR A 266
LEU A 354
VAL A 378
 None
 1.30A 6g2pA-4pv4A:
undetectable		 6g2pA-4pv4A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q38 PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24

(Actinoplanes
teichomyceticus) 		no annotation 4 TYR A 113
LEU A 143
TYR A 109
VAL A  50
 None
 1.33A 6g2pA-4q38A:
undetectable		 6g2pA-4q38A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rg1 C9ORF114

(Homo sapiens) 		PF02598
(Methyltrn_RNA_3) 		4 ARG A 265
TYR A 283
LEU A  75
VAL A 109
 None
 1.19A 6g2pA-4rg1A:
2.0		 6g2pA-4rg1A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwq SULFUR OXIDATION
PROTEIN SOXB

(Thermus
thermophilus) 		PF02872
(5_nucleotid_C) 		4 TYR A 383
LEU A 395
TYR A 389
VAL A 553
 None
 1.24A 6g2pA-4uwqA:
undetectable		 6g2pA-4uwqA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6q GLUCOSYLTRANSFERASE

(Streptococcus
agalactiae) 		no annotation 4 ARG A 179
TYR A 242
LEU A 247
VAL A 229
 UDP  A 402 ( 3.6A)
None
None
None
 1.33A 6g2pA-4w6qA:
undetectable		 6g2pA-4w6qA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8y CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 ARG A 275
TYR A  11
LEU A 134
VAL A 137
 None
 1.24A 6g2pA-4w8yA:
undetectable		 6g2pA-4w8yA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd0 1-(5-PHOSPHORIBOSYL)
-5-[(5-PHOSPHORIBOSY
LAMINO)METHYLIDENEAM
INO]
IMIDAZOLE-4-CARBOXAM
IDE ISOMERASE

(Paenarthrobacter
aurescens) 		PF00977
(His_biosynth) 		4 LEU A 113
TYR A 168
VAL A 156
TRP A 154
 None
 1.30A 6g2pA-4wd0A:
undetectable		 6g2pA-4wd0A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xdo LYSINE-SPECIFIC
DEMETHYLASE 4C

(Homo sapiens) 		PF02373
(JmjC)
PF02375
(JmjN) 		4 ARG A 297
LEU A 159
TYR A 197
VAL A 158
 None
 1.30A 6g2pA-4xdoA:
undetectable		 6g2pA-4xdoA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xii CHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 HIS A  77
LEU A 448
TYR A 440
VAL A 127
 None
 1.39A 6g2pA-4xiiA:
undetectable		 6g2pA-4xiiA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yla AROMATIC
PRENYLTRANSFERASE

(Marinactinospora
thermotolerans) 		PF11991
(Trp_DMAT) 		4 TYR A 125
HIS A 160
LEU A 141
VAL A 140
 None
 1.08A 6g2pA-4ylaA:
undetectable		 6g2pA-4ylaA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwo ORGANOPHOSPHATE
ANHYDROLASE/PROLIDAS
E

(Alteromonas sp.) 		PF00557
(Peptidase_M24) 		4 TYR A 128
HIS A  34
LEU A 119
VAL A 115
 None
 1.17A 6g2pA-4zwoA:
undetectable		 6g2pA-4zwoA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0s LIN0857 PROTEIN

(Listeria
innocua) 		PF04041
(Glyco_hydro_130) 		4 ARG A 238
TYR A 264
LEU A 280
VAL A 288
 None
 0.99A 6g2pA-5b0sA:
undetectable		 6g2pA-5b0sA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpv POLYMERASE COFACTOR
VP35

(Zaire
ebolavirus) 		PF02097
(Filo_VP35) 		4 ARG A 312
LEU A 242
VAL A 325
TRP A 324
 None
 1.13A 6g2pA-5bpvA:
undetectable		 6g2pA-5bpvA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eco GLUTATHIONE
S-TRANSFERASE U20

(Arabidopsis
thaliana) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 TYR B  73
HIS B  59
LEU B  23
VAL B  28
 None
 1.30A 6g2pA-5ecoB:
undetectable		 6g2pA-5ecoB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5efr BAMA-BAMD FUSION
PROTEIN

(Rhodothermus
marinus) 		PF07244
(POTRA)
PF13525
(YfiO) 		4 ARG A1212
TYR A1171
LEU A1176
TYR A1190
 None
 1.38A 6g2pA-5efrA:
undetectable		 6g2pA-5efrA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1y MCCC FAMILY PROTEIN

(Bacillus cereus) 		PF02016
(Peptidase_S66) 		4 TYR A 115
HIS A 313
TYR A 134
VAL A 219
 None
 1.29A 6g2pA-5f1yA:
undetectable		 6g2pA-5f1yA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5a GLUTATHIONE
S-TRANSFERASE U25

(Arabidopsis
thaliana) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 TYR A  73
HIS A  59
LEU A  23
VAL A  28
 None
 1.21A 6g2pA-5g5aA:
undetectable		 6g2pA-5g5aA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5f TAU CLASS
GLUTATHIONE
S-TRANSFERASE

(Mangifera
indica) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 TYR A  74
HIS A  60
LEU A  24
VAL A  29
 None
 1.20A 6g2pA-5g5fA:
undetectable		 6g2pA-5g5fA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hh3 OXYA PROTEIN

(Actinoplanes
teichomyceticus) 		PF00067
(p450) 		4 ARG A 171
HIS A 168
VAL A 137
TRP A 142
 None
 1.36A 6g2pA-5hh3A:
undetectable		 6g2pA-5hh3A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iku COLLAGENASE

(Hathewaya
histolytica) 		PF04151
(PPC) 		4 TYR A 994
LEU A 946
TYR A 996
VAL A 978
 None
 1.27A 6g2pA-5ikuA:
undetectable		 6g2pA-5ikuA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN

(Populus
trichocarpa) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 TYR A  74
HIS A  60
LEU A  24
VAL A  29
 None
 1.21A 6g2pA-5j4uA:
undetectable		 6g2pA-5j4uA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j4u GLUTATHIONE
TRANSFERASE FAMILY
PROTEIN

(Populus
trichocarpa) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 TYR A 186
LEU A 191
TYR A 145
VAL A 196
 None
 1.34A 6g2pA-5j4uA:
undetectable		 6g2pA-5j4uA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbr SERINE/THREONINE-PRO
TEIN KINASE PAK 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 464
LEU A 473
VAL A 436
TRP A 448
 None
 0.91A 6g2pA-5kbrA:
undetectable		 6g2pA-5kbrA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lrb ALPHA-1,4 GLUCAN
PHOSPHORYLASE

(Hordeum vulgare) 		PF00343
(Phosphorylase) 		4 ARG A 359
TYR A 204
LEU A 191
TYR A 130
 None
 1.34A 6g2pA-5lrbA:
0.9		 6g2pA-5lrbA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o84 GLUTATHIONE
S-TRANSFERASE U23

(Arabidopsis
thaliana) 		no annotation 4 TYR A  73
HIS A  59
LEU A  23
VAL A  28
 None
 1.20A 6g2pA-5o84A:
undetectable		 6g2pA-5o84A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT B

(Methanothermococcus
thermolithotrophicus) 		PF02754
(CCG) 		4 TYR B  15
HIS B 235
LEU B 277
VAL B 284
 None
 1.00A 6g2pA-5odrB:
undetectable		 6g2pA-5odrB:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0s MEDIATOR COMPLEX
SUBUNIT 8
MEDIATOR COMPLEX
SUBUNIT 18

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF10232
(Med8)
PF09637
(Med18) 		4 ARG R  97
TYR R 141
HIS R 168
LEU H 188
 None
 1.24A 6g2pA-5u0sR:
undetectable		 6g2pA-5u0sR:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vm9 PROTEIN ARGONAUTE-3

(Homo sapiens) 		no annotation 4 ARG A 813
HIS A 817
TYR A 858
VAL A 630
 A  B   1 ( 4.9A)
None
None
None
 1.31A 6g2pA-5vm9A:
undetectable		 6g2pA-5vm9A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2j RNAP1

(Escherichia
virus N4) 		no annotation 4 LEU A 260
TYR A 211
VAL A 259
TRP A 176
 None
 1.38A 6g2pA-6c2jA:
undetectable		 6g2pA-6c2jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dip NOCTURNIN

(Homo sapiens) 		no annotation 4 ARG A 127
TYR A 348
LEU A 132
VAL A 130
 None
 0.92A 6g2pA-6dipA:
undetectable		 6g2pA-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6esd FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA

(Chromobacterium
violaceum) 		no annotation 6 ARG B  64
TYR B 143
HIS B 163
TYR B 309
VAL B 363
TRP B 397
 CL  B 502 ( 3.6A)
None
CL  B 502 ( 4.9A)
None
None
FAD  B 501 (-4.9A)
 0.44A 6g2pA-6esdB:
63.1		 6g2pA-6esdB:
undetectable