SIMILAR PATTERNS OF AMINO ACIDS FOR 6G1P_B_ACTB403
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8v | MATURE CAPSIDPROTEIN BETA (Pariacoto virus) |
PF01829(Peptidase_A6) | 3 | PHE A 81ARG A 160GLN A 320 | None | 1.10A | 6g1pB-1f8vA:0.0 | 6g1pB-1f8vA:23.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iah | TRANSIENT RECEPTORPOTENTIAL-RELATEDPROTEIN (Mus musculus) |
PF02816(Alpha_kinase) | 3 | PHE A1791ARG A1671GLN A1675 | None | 1.17A | 6g1pB-1iahA:undetectable | 6g1pB-1iahA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmc | PROTEIN (REPLICATIONPROTEIN A (RPA)) (Homo sapiens) |
PF01336(tRNA_anti-codon)PF16900(REPA_OB_2) | 3 | PHE A 415ARG A 412GLN A 420 | None | 1.02A | 6g1pB-1jmcA:undetectable | 6g1pB-1jmcA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8f | ENDOGLUCANASE (Melanocarpusalbomyces) |
PF02015(Glyco_hydro_45) | 3 | PHE A 41ARG A 19GLN A 26 | None | 1.10A | 6g1pB-1l8fA:undetectable | 6g1pB-1l8fA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpo | MALTOPORIN (Escherichiacoli) |
PF02264(LamB) | 3 | PHE A 23ARG A 405GLN A 21 | None | 0.79A | 6g1pB-1mpoA:undetectable | 6g1pB-1mpoA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n76 | LACTOFERRIN (Homo sapiens) |
PF00405(Transferrin) | 3 | PHE A 20ARG A 24GLN A 23 | None | 0.93A | 6g1pB-1n76A:0.0 | 6g1pB-1n76A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nd7 | WW DOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00632(HECT) | 3 | PHE A 891ARG A 893GLN A 871 | None | 1.03A | 6g1pB-1nd7A:0.0 | 6g1pB-1nd7A:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ohf | NUDAURELIA CAPENSISOMEGA VIRUS CAPSIDPROTEIN (Nudaureliacapensis omegavirus) |
PF03566(Peptidase_A21) | 3 | PHE A 491ARG A 495GLN A 324 | None | 1.17A | 6g1pB-1ohfA:0.0 | 6g1pB-1ohfA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r6m | RIBONUCLEASE PH (Pseudomonasaeruginosa) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 3 | PHE A 230ARG A 234GLN A 233 | None | 1.08A | 6g1pB-1r6mA:undetectable | 6g1pB-1r6mA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tlv | TRANSCRIPTIONANTITERMINATOR LICT (Bacillussubtilis) |
PF00874(PRD) | 3 | PHE A 210ARG A 214GLN A 213 | None | 1.15A | 6g1pB-1tlvA:0.0 | 6g1pB-1tlvA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w4t | ARYLAMINEN-ACETYLTRANSFERASE (Pseudomonasaeruginosa) |
PF00797(Acetyltransf_2) | 3 | PHE A 228ARG A 240GLN A 230 | None | 1.10A | 6g1pB-1w4tA:0.0 | 6g1pB-1w4tA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xls | ORPHAN NUCLEARRECEPTOR NR1I3 (Mus musculus) |
PF00104(Hormone_recep) | 3 | PHE E 145ARG E 146GLN E 144 | None | 1.18A | 6g1pB-1xlsE:0.3 | 6g1pB-1xlsE:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv9 | ORPHAN NUCLEARRECEPTOR NR1I3 (Homo sapiens) |
PF00104(Hormone_recep) | 3 | PHE B 135ARG B 136GLN B 134 | None | 1.03A | 6g1pB-1xv9B:0.0 | 6g1pB-1xv9B:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z14 | VP2 (Rodentprotoparvovirus1) |
PF00740(Parvo_coat) | 3 | PHE A 338ARG A 407GLN A 340 | None | 1.00A | 6g1pB-1z14A:undetectable | 6g1pB-1z14A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z1n | SIXTEEN HEMECYTOCHROME (Desulfovibriogigas) |
PF02085(Cytochrom_CIII)PF14522(Cytochrome_C7) | 3 | PHE X 487ARG X 490GLN X 488 | None | 1.14A | 6g1pB-1z1nX:0.0 | 6g1pB-1z1nX:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5u | COLICIN E3 (Escherichiacoli) |
PF03515(Cloacin)PF09000(Cytotoxic)PF11570(E2R135) | 3 | PHE A 375ARG A 377GLN A 374 | None | 1.16A | 6g1pB-2b5uA:undetectable | 6g1pB-2b5uA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cly | ATP SYNTHASE BCHAIN, MITOCHONDRIAL (Bos taurus) |
PF05405(Mt_ATP-synt_B) | 3 | PHE A 125ARG A 129GLN A 128 | None | 0.74A | 6g1pB-2clyA:undetectable | 6g1pB-2clyA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7c | RAB11FAMILY-INTERACTINGPROTEIN 3 (Homo sapiens) |
PF09457(RBD-FIP) | 3 | PHE C 732ARG C 733GLN C 735 | None | 0.99A | 6g1pB-2d7cC:undetectable | 6g1pB-2d7cC:10.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dn0 | ZINC FINGERS ANDHOMEOBOXES PROTEIN 3 (Homo sapiens) |
PF00046(Homeobox) | 3 | PHE A 32ARG A 60GLN A 31 | None | 1.14A | 6g1pB-2dn0A:undetectable | 6g1pB-2dn0A:12.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f1z | UBIQUITINCARBOXYL-TERMINALHYDROLASE 7 (Homo sapiens) |
PF00443(UCH)PF00917(MATH) | 3 | PHE A 234ARG A 239GLN A 230 | None | 1.16A | 6g1pB-2f1zA:undetectable | 6g1pB-2f1zA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3t | TRAFFICKING PROTEINPARTICLE COMPLEXSUBUNIT 6A (Homo sapiens) |
PF04051(TRAPP) | 3 | PHE B 42ARG B 43GLN B 46 | None | 0.92A | 6g1pB-2j3tB:undetectable | 6g1pB-2j3tB:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kgl | MESODERM DEVELOPMENTCANDIDATE 2 (Mus musculus) |
PF10185(Mesd) | 3 | PHE A 112ARG A 111GLN A 110 | None | 1.11A | 6g1pB-2kglA:undetectable | 6g1pB-2kglA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2moq | IRON-REGULATEDSURFACE DETERMINANTPROTEIN B (Staphylococcusaureus) |
PF05031(NEAT) | 3 | PHE A 194ARG A 130GLN A 193 | None | 1.17A | 6g1pB-2moqA:undetectable | 6g1pB-2moqA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2moq | IRON-REGULATEDSURFACE DETERMINANTPROTEIN B (Staphylococcusaureus) |
PF05031(NEAT) | 3 | PHE A 242ARG A 130GLN A 193 | None | 0.99A | 6g1pB-2moqA:undetectable | 6g1pB-2moqA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mpr | MALTOPORIN (Salmonellaenterica) |
PF02264(LamB) | 3 | PHE A 23ARG A 411GLN A 21 | None | 0.91A | 6g1pB-2mprA:undetectable | 6g1pB-2mprA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odp | COMPLEMENT C2 (Homo sapiens) |
PF00089(Trypsin)PF00092(VWA) | 3 | PHE A 713ARG A 714GLN A 716 | None | 1.18A | 6g1pB-2odpA:undetectable | 6g1pB-2odpA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbp | ENOYL-COA HYDRATASESUBUNIT I (Geobacilluskaustophilus) |
PF00378(ECH_1) | 3 | PHE A 255ARG A 51GLN A 200 | None | 1.06A | 6g1pB-2pbpA:undetectable | 6g1pB-2pbpA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q0f | RNA URIDYLYLTRANSFERASE (Trypanosomabrucei) |
PF03828(PAP_assoc) | 3 | PHE A 247ARG A 202GLN A 201 | None | 1.09A | 6g1pB-2q0fA:undetectable | 6g1pB-2q0fA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5j | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus9) |
PF00500(Late_protein_L1) | 3 | PHE A 305ARG A 336GLN A 155 | None | 1.18A | 6g1pB-2r5jA:undetectable | 6g1pB-2r5jA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5j | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus9) |
PF00500(Late_protein_L1) | 3 | PHE A 462ARG A 466GLN A 461 | None | 1.04A | 6g1pB-2r5jA:undetectable | 6g1pB-2r5jA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5k | MAJOR CAPSID PROTEINL1 (Alphapapillomavirus10) |
PF00500(Late_protein_L1) | 3 | PHE A 458ARG A 462GLN A 457 | None | 1.06A | 6g1pB-2r5kA:undetectable | 6g1pB-2r5kA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wss | ATP SYNTHASE SUBUNITB, MITOCHONDRIAL (Bos taurus) |
PF05405(Mt_ATP-synt_B) | 3 | PHE T 125ARG T 129GLN T 128 | None | 1.09A | 6g1pB-2wssT:undetectable | 6g1pB-2wssT:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x40 | BETA-GLUCOSIDASE (Thermotoganeapolitana) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 3 | PHE A 559ARG A 124GLN A 170 | None | 1.15A | 6g1pB-2x40A:undetectable | 6g1pB-2x40A:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xf2 | CATALASE (Penicilliumjanthinellum) |
PF00199(Catalase)PF06628(Catalase-rel) | 3 | PHE A 681ARG A 684GLN A 656 | None | 0.98A | 6g1pB-2xf2A:undetectable | 6g1pB-2xf2A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjc | CGMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 3 | PHE A 736ARG A 740GLN A 827 | None | 1.14A | 6g1pB-3bjcA:undetectable | 6g1pB-3bjcA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5l | REGULATORY PROTEINRECX (Lactobacillusreuteri) |
PF02631(RecX) | 3 | PHE A 36ARG A 37GLN A 35 | None | 1.12A | 6g1pB-3d5lA:undetectable | 6g1pB-3d5lA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 ALPHACHAIN (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF14710(Nitr_red_alph_N) | 3 | PHE A 996ARG A 997GLN A1000 | None | 1.11A | 6g1pB-3egwA:undetectable | 6g1pB-3egwA:13.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5t | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Corynebacteriumglutamicum) |
PF00356(LacI)PF13377(Peripla_BP_3) | 3 | PHE A 256ARG A 252GLN A 253 | None | 1.13A | 6g1pB-3h5tA:undetectable | 6g1pB-3h5tA:24.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hq9 | CYTOCHROME C551PEROXIDASE (Geobactersulfurreducens) |
PF00034(Cytochrom_C)PF03150(CCP_MauG) | 3 | PHE A 115ARG A 268GLN A 114 | BU3 A 350 ( 4.2A)HEM A 400 (-4.3A)BU3 A 350 (-4.1A) | 1.00A | 6g1pB-3hq9A:undetectable | 6g1pB-3hq9A:24.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3inn | PANTOTHENATESYNTHETASE (Brucellamelitensis) |
PF02569(Pantoate_ligase) | 3 | PHE A 62ARG A 121GLN A 61 | UNX A 303 ( 4.0A)UNX A 303 ( 3.3A)ATP A 300 (-3.1A) | 1.17A | 6g1pB-3innA:undetectable | 6g1pB-3innA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2v | PREC/CORE PROTEIN (Hepatitis Bvirus) |
no annotation | 3 | PHE C 24ARG C 98GLN C 99 | None | 1.03A | 6g1pB-3j2vC:undetectable | 6g1pB-3j2vC:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kew | DHHA1 DOMAIN PROTEIN (Clostridiumperfringens) |
PF01411(tRNA-synt_2c)PF07973(tRNA_SAD) | 3 | PHE A 38ARG A 89GLN A 44 | None | 0.83A | 6g1pB-3kewA:undetectable | 6g1pB-3kewA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krm | INSULIN-LIKE GROWTHFACTOR 2MRNA-BINDING PROTEIN1 (Homo sapiens) |
PF00013(KH_1) | 3 | PHE A 464ARG A 551GLN A 547 | None | 1.17A | 6g1pB-3krmA:undetectable | 6g1pB-3krmA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l7g | XAA-PRO DIPEPTIDASE (Alteromonas sp.) |
PF00557(Peptidase_M24) | 3 | PHE A 230ARG A 232GLN A 197 | None | 0.93A | 6g1pB-3l7gA:undetectable | 6g1pB-3l7gA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmm | UNCHARACTERIZEDPROTEIN (Corynebacteriumdiphtheriae) |
PF04326(AlbA_2)PF13749(HATPase_c_4) | 3 | PHE A 110ARG A 106GLN A 107 | None | 1.12A | 6g1pB-3lmmA:undetectable | 6g1pB-3lmmA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mca | ELONGATION FACTOR 1ALPHA-LIKE PROTEIN (Schizosaccharomycespombe) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3) | 3 | PHE A 505ARG A 546GLN A 503 | None | 0.87A | 6g1pB-3mcaA:undetectable | 6g1pB-3mcaA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ovk | AMINOPEPTIDASE P,XAA-PRO DIPEPTIDASE (Streptococcuspyogenes) |
PF01321(Creatinase_N) | 3 | PHE A 4ARG A 8GLN A 7 | None | 1.00A | 6g1pB-3ovkA:undetectable | 6g1pB-3ovkA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p30 | 1281 FAB HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 3 | PHE H 63ARG H 66GLN H 62 | None | 1.11A | 6g1pB-3p30H:undetectable | 6g1pB-3p30H:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3shq | UBLCP1 (Drosophilamelanogaster) |
PF00240(ubiquitin)PF03031(NIF) | 3 | PHE A 35ARG A 36GLN A 39 | None | 1.16A | 6g1pB-3shqA:undetectable | 6g1pB-3shqA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3swx | PROBABLE ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 3 | PHE A 258ARG A 51GLN A 203 | None | 0.85A | 6g1pB-3swxA:undetectable | 6g1pB-3swxA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uk2 | PANTOTHENATESYNTHETASE (Burkholderiathailandensis) |
PF02569(Pantoate_ligase) | 3 | PHE A 58ARG A 118GLN A 57 | NoneMLT A 284 (-3.3A)EDO A 285 ( 3.0A) | 1.17A | 6g1pB-3uk2A:undetectable | 6g1pB-3uk2A:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uy4 | PANTOTHENATESYNTHETASE (Campylobacterjejuni) |
PF02569(Pantoate_ligase) | 3 | PHE A 61ARG A 120GLN A 60 | NonePAU A 302 (-3.1A)PAU A 302 (-2.9A) | 1.18A | 6g1pB-3uy4A:undetectable | 6g1pB-3uy4A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 3 | PHE A 666ARG A 716GLN A 575 | None | 1.05A | 6g1pB-3w9iA:undetectable | 6g1pB-3w9iA:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zgb | PHOSPHOENOLPYRUVATECARBOXYLASE (Flaveriapringlei) |
PF00311(PEPcase) | 3 | PHE A 682ARG A 683GLN A 686 | None | 1.15A | 6g1pB-3zgbA:undetectable | 6g1pB-3zgbA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq3 | OBP3 PROTEIN (Rattusnorvegicus) |
PF00061(Lipocalin) | 3 | PHE A 39ARG A 175GLN A 62 | None | 1.16A | 6g1pB-3zq3A:undetectable | 6g1pB-3zq3A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b2q | ATP SYNTHASE SUBUNITB, MITOCHONDRIAL (Bos taurus) |
PF05405(Mt_ATP-synt_B) | 3 | PHE T 125ARG T 129GLN T 128 | None | 0.73A | 6g1pB-4b2qT:undetectable | 6g1pB-4b2qT:17.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bpl | IMPORTIN SUBUNITALPHA-1A (Oryza sativa) |
PF00514(Arm)PF16186(Arm_3) | 3 | PHE A 123ARG A 126GLN A 122 | None | 1.07A | 6g1pB-4bplA:undetectable | 6g1pB-4bplA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e0t | CYCLIC DIPEPTIDEN-PRENYLTRANSFERASE (Aspergillusfumigatus) |
PF11991(Trp_DMAT) | 3 | PHE A 146ARG A 148GLN A 204 | None | 1.16A | 6g1pB-4e0tA:undetectable | 6g1pB-4e0tA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f0l | AMIDOHYDROLASE (Brucellaabortus) |
PF01979(Amidohydro_1) | 3 | PHE A 83ARG A 87GLN A 241 | None | 1.00A | 6g1pB-4f0lA:undetectable | 6g1pB-4f0lA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmk | POLIOVIRUSRECEPTOR-RELATEDPROTEIN 2 (Mus musculus) |
PF07686(V-set)PF08205(C2-set_2) | 3 | PHE A 93ARG A 97GLN A 92 | None | 1.14A | 6g1pB-4fmkA:undetectable | 6g1pB-4fmkA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzw | 1,2-EPOXYPHENYLACETYL-COA ISOMERASE (Escherichiacoli) |
PF00378(ECH_1) | 3 | PHE C 259ARG C 49GLN C 204 | None | 1.18A | 6g1pB-4fzwC:undetectable | 6g1pB-4fzwC:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g0r | CAPSID PROTEIN VP1 (Rodentprotoparvovirus1) |
PF00740(Parvo_coat) | 3 | PHE A 344ARG A 413GLN A 346 | None | 0.93A | 6g1pB-4g0rA:undetectable | 6g1pB-4g0rA:18.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g59 | M152 PROTEIN (Muridbetaherpesvirus1) |
PF11624(M157) | 3 | PHE C 78ARG C 77GLN C 75 | None | 0.92A | 6g1pB-4g59C:undetectable | 6g1pB-4g59C:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7e | UREASE (Cajanus cajan) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 3 | PHE B 124ARG B 68GLN B 69 | None | 1.17A | 6g1pB-4g7eB:undetectable | 6g1pB-4g7eB:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gvb | KP6 KILLER TOXINSUBUNIT BETA (Ustilago maydisvirus P6) |
no annotation | 3 | PHE B 45ARG B 47GLN B 75 | None | 0.84A | 6g1pB-4gvbB:undetectable | 6g1pB-4gvbB:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hf7 | PUTATIVEACYLHYDROLASE (Bacteroidesthetaiotaomicron) |
PF13472(Lipase_GDSL_2) | 3 | PHE A 93ARG A 96GLN A 92 | None | 1.17A | 6g1pB-4hf7A:undetectable | 6g1pB-4hf7A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hst | GLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE ALPHA CHAINGLUTARYL-7-AMINOCEPHALOSPORANIC ACIDACYLASE BETA CHAIN (Pseudomonas;Pseudomonas) |
PF01804(Penicil_amidase)PF01804(Penicil_amidase) | 3 | PHE A 170ARG A 174GLN B 373 | None | 1.05A | 6g1pB-4hstA:undetectable | 6g1pB-4hstA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ivn | TRANSCRIPTIONALREGULATOR (Vibriovulnificus) |
PF01380(SIS)PF01418(HTH_6) | 3 | PHE A 38ARG A 71GLN A 37 | None | 1.02A | 6g1pB-4ivnA:undetectable | 6g1pB-4ivnA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcd | MAJOR CAPSID PROTEINVP1 (Humanpolyomavirus 2) |
PF00718(Polyoma_coat) | 3 | PHE A 67ARG A 161GLN A 179 | None | 0.77A | 6g1pB-4jcdA:undetectable | 6g1pB-4jcdA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l6r | SOLUBLE CYTOCHROMEB562 AND GLUCAGONRECEPTOR CHIMERA (Escherichiacoli;Homo sapiens) |
PF00002(7tm_2)PF07361(Cytochrom_B562) | 3 | PHE A 303ARG A 308GLN A 232 | None | 0.98A | 6g1pB-4l6rA:undetectable | 6g1pB-4l6rA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lc3 | PUTATIVEUDP-4-AMINO-4-DEOXY-L-ARABINOSE--OXOGLUTARATEAMINOTRANSFERASE (Burkholderiacenocepacia) |
PF01041(DegT_DnrJ_EryC1) | 3 | PHE A 253ARG A 257GLN A 256 | None | 1.18A | 6g1pB-4lc3A:undetectable | 6g1pB-4lc3A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mj0 | VP1 CAPSID PROTEIN (Humanpolyomavirus 1) |
PF00718(Polyoma_coat) | 3 | PHE A 75ARG A 169GLN A 187 | None | 0.76A | 6g1pB-4mj0A:undetectable | 6g1pB-4mj0A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 3 | PHE A 486ARG A 249GLN A 214 | None | 1.01A | 6g1pB-4nmeA:undetectable | 6g1pB-4nmeA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oe5 | DELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF00171(Aldedh) | 3 | PHE A 449ARG A 399GLN A 346 | None | 1.10A | 6g1pB-4oe5A:undetectable | 6g1pB-4oe5A:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASEDNA-DIRECTED RNAPOLYMERASE SUBUNIT N (Thermococcuskodakarensis;Thermococcuskodakarensis) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF01194(RNA_pol_N) | 3 | PHE B 724ARG N 47GLN B 722 | None | 0.95A | 6g1pB-4qiwB:undetectable | 6g1pB-4qiwB:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbo | PUTATIVE HOMEOBOXPROTEIN NANOGP8 (Homo sapiens) |
PF00046(Homeobox) | 3 | PHE A 143ARG A 147GLN A 117 | None | 1.16A | 6g1pB-4rboA:undetectable | 6g1pB-4rboA:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u6u | COG5 (Kluyveromyceslactis) |
PF10392(COG5) | 3 | PHE B 244ARG B 312GLN B 311 | None | 1.16A | 6g1pB-4u6uB:undetectable | 6g1pB-4u6uB:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwo | ORGANOPHOSPHATEANHYDROLASE/PROLIDASE (Alteromonas sp.) |
PF00557(Peptidase_M24) | 3 | PHE A 230ARG A 232GLN A 197 | None | 0.99A | 6g1pB-4zwoA:undetectable | 6g1pB-4zwoA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3y | THERMOLYSIN (Bacillusthermoproteolyticus) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 3 | PHE A 63ARG A 11GLN A 17 | None | 1.02A | 6g1pB-5a3yA:undetectable | 6g1pB-5a3yA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5anb | ELONGATION FACTOR TUGTP-BINDINGDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF14492(EFG_II) | 3 | PHE K1065ARG K1088GLN K 978 | None | 0.86A | 6g1pB-5anbK:undetectable | 6g1pB-5anbK:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bn4 | V-TYPE ATP SYNTHASEALPHA CHAINNEQ263 (Nanoarchaeumequitans;Nanoarchaeumequitans) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N)PF16886(ATP-synt_ab_Xtn)PF00006(ATP-synt_ab) | 3 | PHE A 225ARG B 326GLN B 302 | NoneANP A 601 (-3.0A)None | 0.95A | 6g1pB-5bn4A:undetectable | 6g1pB-5bn4A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c91 | E3 UBIQUITIN-PROTEINLIGASE NEDD4 (Homo sapiens) |
PF00632(HECT) | 3 | PHE A 868ARG A 870GLN A 848 | None | 1.13A | 6g1pB-5c91A:undetectable | 6g1pB-5c91A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cfc | VP1 (Cardiovirus B) |
no annotation | 3 | PHE A 35ARG A 32GLN A 30 | None | 1.16A | 6g1pB-5cfcA:undetectable | 6g1pB-5cfcA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cq9 | SECRETED EFFECTORPROTEIN SOPD2 (Salmonellaenterica) |
PF11047(SopD) | 3 | PHE A 223ARG A 216GLN A 228 | None | 1.13A | 6g1pB-5cq9A:undetectable | 6g1pB-5cq9A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f70 | HEPATITIS A VIRUSCELLULAR RECEPTOR 1 (Homo sapiens) |
PF07686(V-set) | 3 | PHE A 36ARG A 87GLN A 39 | None | 0.78A | 6g1pB-5f70A:undetectable | 6g1pB-5f70A:13.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5foe | GDP-FUCOSE PROTEINO-FUCOSYLTRANSFERASE2,THROMBOSPONDIN-1 (Caenorhabditiselegans;Homo sapiens) |
PF00090(TSP_1)PF10250(O-FucT) | 3 | PHE A 386ARG A 387GLN A 389 | None | 0.94A | 6g1pB-5foeA:1.6 | 6g1pB-5foeA:24.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gmh | TOLL-LIKE RECEPTOR 7 (Macaca mulatta) |
PF00560(LRR_1)PF13306(LRR_5)PF13855(LRR_8) | 3 | PHE A 420ARG A 422GLN A 419 | NoneSO4 A 917 (-3.9A)None | 1.13A | 6g1pB-5gmhA:undetectable | 6g1pB-5gmhA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hpk | E3 UBIQUITIN-PROTEINLIGASE NEDD4-LIKE (Homo sapiens) |
PF00632(HECT) | 3 | PHE A 923ARG A 925GLN A 903 | None | 0.98A | 6g1pB-5hpkA:undetectable | 6g1pB-5hpkA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibx | TRIOSEPHOSPHATEISOMERASE (Streptococcuspneumoniae) |
PF00121(TIM) | 3 | PHE A 6ARG A 208GLN A 210 | None | 1.01A | 6g1pB-5ibxA:undetectable | 6g1pB-5ibxA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxf | ASP/GLU-SPECIFICDIPEPTIDYL-PEPTIDASE (Flavobacteriumpsychrophilum) |
PF10459(Peptidase_S46) | 3 | PHE A 560ARG A 558GLN A 18 | None | 1.09A | 6g1pB-5jxfA:undetectable | 6g1pB-5jxfA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ku5 | SENSOR KINASE CUSS (Escherichiacoli) |
no annotation | 3 | PHE A 43ARG A 149GLN A 46 | AG A 202 (-3.2A)NoneNone | 1.17A | 6g1pB-5ku5A:undetectable | 6g1pB-5ku5A:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m3x | ANGIOTENSINOGEN (Homo sapiens) |
no annotation | 3 | PHE A 79ARG A 83GLN A 330 | None | 0.90A | 6g1pB-5m3xA:undetectable | 6g1pB-5m3xA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkk | MULTIDRUG RESISTANCEABC TRANSPORTERATP-BINDING ANDPERMEASE PROTEIN (Thermusthermophilus) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 3 | PHE A 597ARG A 594GLN A 598 | None | 1.17A | 6g1pB-5mkkA:undetectable | 6g1pB-5mkkA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | 40S RIBOSOMALPROTEIN SA (Trypanosomacruzi) |
no annotation | 3 | PHE f 91ARG f 88GLN f 95 | None | 1.13A | 6g1pB-5optf:undetectable | 6g1pB-5optf:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | RIBOSOMAL PROTEINS19, PUTATIVE (Trypanosomacruzi) |
no annotation | 3 | PHE o 39ARG o 62GLN o 41 | NoneNone A E2031 ( 3.7A) | 1.10A | 6g1pB-5opto:undetectable | 6g1pB-5opto:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tj7 | NEDD4-LIKE E3UBIQUITIN-PROTEINLIGASE WWP2 (Homo sapiens) |
PF00397(WW)PF00632(HECT) | 3 | PHE A 839ARG A 841GLN A 819 | None | 1.10A | 6g1pB-5tj7A:undetectable | 6g1pB-5tj7A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tw7 | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Neisseriagonorrhoeae) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 3 | PHE A 444ARG A 256GLN A 442 | None | 1.14A | 6g1pB-5tw7A:undetectable | 6g1pB-5tw7A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xnl | CYTOCHROME B559SUBUNIT ALPHA (Pisum sativum) |
PF00283(Cytochrom_B559)PF00284(Cytochrom_B559a) | 3 | PHE E 56ARG E 60GLN E 61 | None | 1.13A | 6g1pB-5xnlE:undetectable | 6g1pB-5xnlE:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b3r | PIEZO-TYPEMECHANOSENSITIVE IONCHANNEL COMPONENT 1 (Mus musculus) |
no annotation | 3 | PHE A2272ARG A2377GLN A2275 | None | 1.09A | 6g1pB-6b3rA:undetectable | 6g1pB-6b3rA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eid | ARCHAEAL-TYPE OPSIN2 (Chlamydomonasreinhardtii) |
no annotation | 3 | PHE A 102ARG A 115GLN A 117 | None | 1.18A | 6g1pB-6eidA:undetectable | 6g1pB-6eidA:23.02 |