SIMILAR PATTERNS OF AMINO ACIDS FOR 6FGD_A_ACTA824_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aor ALDEHYDE FERREDOXIN
OXIDOREDUCTASE

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 LEU A 551
ASP A 428
PRO A 429
ARG A 430
 None
 1.06A 6fgdA-1aorA:
undetectable		 6fgdA-1aorA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dyp KAPPA-CARRAGEENASE

(Pseudoalteromonas
carrageenovora) 		PF00722
(Glyco_hydro_16) 		4 LEU A 169
ASP A 213
PRO A 214
ARG A 215
 None
 1.10A 6fgdA-1dypA:
undetectable		 6fgdA-1dypA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1h BOTULINUM NEUROTOXIN
TYPE A LIGHT CHAIN

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A  93
ASP A 215
PRO A 216
ARG A  96
 None
 1.43A 6fgdA-1e1hA:
undetectable		 6fgdA-1e1hA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3d [NIFE] HYDROGENASE
LARGE SUBUNIT

(Desulfovibrio
desulfuricans) 		PF00374
(NiFeSe_Hases) 		4 LEU B  86
ASP B  59
PRO B  60
ARG B  61
 None
 1.37A 6fgdA-1e3dB:
undetectable		 6fgdA-1e3dB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f82 BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 385
ASP A 222
PRO A 223
ARG A  97
 None
 1.02A 6fgdA-1f82A:
undetectable		 6fgdA-1f82A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g3r CELL DIVISION
INHIBITOR

(Pyrococcus
furiosus) 		PF13614
(AAA_31) 		4 LEU A 125
ASP A  97
PRO A  98
ARG A  99
 None
 0.73A 6fgdA-1g3rA:
1.2		 6fgdA-1g3rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i71 APOLIPOPROTEIN(A)

(Homo sapiens) 		PF00051
(Kringle) 		4 LEU A  45
ASP A  54
PRO A  53
ARG A  35
 None
None
None
SO4  A 300 (-3.6A)
 1.30A 6fgdA-1i71A:
undetectable		 6fgdA-1i71A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ij9 VASCULAR CELL
ADHESION PROTEIN 1

(Homo sapiens) 		PF05790
(C2-set)
PF07679
(I-set) 		4 LEU A 175
ASP A 122
PRO A 120
ARG A 123
 None
 1.38A 6fgdA-1ij9A:
undetectable		 6fgdA-1ij9A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ion PROBABLE CELL
DIVISION INHIBITOR
MIND

(Pyrococcus
horikoshii) 		PF13614
(AAA_31) 		4 LEU A 125
ASP A  97
PRO A  98
ARG A  99
 None
 0.80A 6fgdA-1ionA:
undetectable		 6fgdA-1ionA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmy BILE-SALT-ACTIVATED
LIPASE

(Homo sapiens) 		PF00135
(COesterase) 		4 LEU A  65
ASP A 262
PRO A 263
ARG A 264
 None
 1.27A 6fgdA-1jmyA:
2.9		 6fgdA-1jmyA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfw CHITINASE B

(Arthrobacter
sp. TAD20) 		PF00704
(Glyco_hydro_18) 		4 LEU A 281
ASP A 294
PRO A 295
ARG A 296
 None
 1.02A 6fgdA-1kfwA:
undetectable		 6fgdA-1kfwA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lq2 BETA-D-GLUCAN
GLUCOHYDROLASE
ISOENZYME EXO1

(Hordeum vulgare) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 LEU A 499
ASP A 153
PRO A 154
ARG A 155
 None
 1.07A 6fgdA-1lq2A:
undetectable		 6fgdA-1lq2A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pv5 HYPOTHETICAL PROTEIN
YWQG

(Bacillus
subtilis) 		PF09234
(DUF1963) 		4 LEU A 255
ASP A 205
PRO A 206
ARG A 207
 None
 1.03A 6fgdA-1pv5A:
undetectable		 6fgdA-1pv5A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5m PROSTAGLANDIN-E2
9-REDUCTASE

(Oryctolagus
cuniculus) 		PF00248
(Aldo_ket_red) 		4 LEU A  94
ASP A 140
PRO A 124
ARG A  91
 None
 1.38A 6fgdA-1q5mA:
undetectable		 6fgdA-1q5mA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zb7 NEUROTOXIN

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A  95
ASP A 223
PRO A 224
ARG A  98
 None
 1.40A 6fgdA-1zb7A:
undetectable		 6fgdA-1zb7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zb7 NEUROTOXIN

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 385
ASP A 223
PRO A 224
ARG A  98
 None
 0.99A 6fgdA-1zb7A:
undetectable		 6fgdA-1zb7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcc GLYCEROPHOSPHODIESTE
R PHOSPHODIESTERASE

(Agrobacterium
fabrum) 		PF03009
(GDPD) 		4 LEU A 222
ASP A 226
PRO A 225
ARG A 224
 None
 1.20A 6fgdA-1zccA:
2.2		 6fgdA-1zccA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl6 BOTULINUM NEUROTOXIN
TYPE E

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 362
ASP A 204
PRO A 205
ARG A  92
 None
 0.95A 6fgdA-1zl6A:
undetectable		 6fgdA-1zl6A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aey FRUCTAN
1-EXOHYDROLASE IIA

(Cichorium
intybus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 LEU A 376
ASP A 464
PRO A 465
ARG A 466
 None
 1.10A 6fgdA-2aeyA:
undetectable		 6fgdA-2aeyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6x CITRATE SYNTHASE 1

(Bacillus
subtilis) 		PF00285
(Citrate_synt) 		4 LEU A  26
ASP A 259
PRO A 260
ARG A 261
 None
None
None
CIT  A1366 (-3.3A)
 1.13A 6fgdA-2c6xA:
undetectable		 6fgdA-2c6xA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ewo PUTATIVE AGMATINE
DEIMINASE

(Streptococcus
mutans) 		PF04371
(PAD_porph) 		4 LEU A 106
ASP A  13
PRO A  10
ARG A 114
 None
 1.15A 6fgdA-2ewoA:
2.5		 6fgdA-2ewoA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hp3 IDS-EPIMERASE

(Agrobacterium
tumefaciens) 		PF03972
(MmgE_PrpD) 		4 LEU A 348
ASP A 314
PRO A 315
ARG A 316
 None
 0.92A 6fgdA-2hp3A:
undetectable		 6fgdA-2hp3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2np0 BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 LEU A  94
ASP A 222
PRO A 223
ARG A  97
 None
 1.36A 6fgdA-2np0A:
undetectable		 6fgdA-2np0A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2np0 BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 LEU A 385
ASP A 222
PRO A 223
ARG A  97
 None
 0.93A 6fgdA-2np0A:
undetectable		 6fgdA-2np0A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nz9 BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N) 		4 LEU A  94
ASP A 216
PRO A 217
ARG A  97
 None
 1.40A 6fgdA-2nz9A:
undetectable		 6fgdA-2nz9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2om6 PROBABLE
PHOSPHOSERINE
PHOSPHATASE

(Pyrococcus
horikoshii) 		PF13419
(HAD_2) 		4 LEU A 155
ASP A  61
PRO A  62
ARG A  63
 None
 1.17A 6fgdA-2om6A:
2.1		 6fgdA-2om6A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq6 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  99
ASP A  60
PRO A  61
ARG A  62
 None
 1.38A 6fgdA-2qq6A:
2.2		 6fgdA-2qq6A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq6 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 103
ASP A  60
PRO A  61
ARG A  62
 None
 1.35A 6fgdA-2qq6A:
2.2		 6fgdA-2qq6A:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw THIOSULFATE
REDUCTASE

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 LEU A 622
ASP A 236
PRO A 237
ARG A 238
 MGD  A1766 (-3.9A)
MGD  A1766 (-2.6A)
MGD  A1766 (-4.4A)
MGD  A1766 (-3.5A)
 1.15A 6fgdA-2vpwA:
undetectable		 6fgdA-2vpwA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1j PUTATIVE SORTASE

(Streptococcus
pneumoniae) 		PF04203
(Sortase) 		4 LEU A 191
ASP A  58
PRO A  59
ARG A 202
 None
 1.11A 6fgdA-2w1jA:
undetectable		 6fgdA-2w1jA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqk 5'-NUCLEOTIDASE SURE

(Aquifex
aeolicus) 		PF01975
(SurE) 		4 LEU A  39
ASP A  36
PRO A  35
ARG A  37
 None
 1.28A 6fgdA-2wqkA:
4.4		 6fgdA-2wqkA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xqy ENVELOPE
GLYCOPROTEIN H

(Suid
alphaherpesvirus
1) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 LEU A 464
ASP A 486
PRO A 487
ARG A 461
 None
 1.17A 6fgdA-2xqyA:
undetectable		 6fgdA-2xqyA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr1 CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
100 KD SUBUNIT

(Methanosarcina
mazei) 		PF07521
(RMMBL)
PF07650
(KH_2)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		4 LEU A 156
ASP A  99
PRO A  98
ARG A 159
 None
 1.36A 6fgdA-2xr1A:
undetectable		 6fgdA-2xr1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ykf PROBABLE SENSOR
HISTIDINE KINASE
PDTAS

(Mycobacterium
tuberculosis) 		PF12282
(H_kinase_N) 		4 LEU A 259
ASP A 179
PRO A 175
ARG A 279
 None
 1.23A 6fgdA-2ykfA:
undetectable		 6fgdA-2ykfA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr5 PRO-ENZYME OF
L-PHENYLALANINE
OXIDASE

(Pseudomonas sp.
P-501) 		no annotation 4 LEU A 332
ASP A  35
PRO A  34
ARG A 329
 None
 1.42A 6fgdA-2yr5A:
3.6		 6fgdA-2yr5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana) 		PF00348
(polyprenyl_synt) 		4 LEU A 339
ASP A   9
PRO A  10
ARG A 342
 None
 1.26A 6fgdA-3aq0A:
undetectable		 6fgdA-3aq0A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayt PUTATIVE
UNCHARACTERIZED
PROTEIN TTHB071

(Thermus
thermophilus) 		PF01261
(AP_endonuc_2) 		4 LEU A   5
ASP A 227
PRO A 228
ARG A  18
 None
 1.42A 6fgdA-3aytA:
undetectable		 6fgdA-3aytA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejn SUSD HOMOLOG

(Bacteroides
fragilis) 		PF12771
(SusD-like_2) 		4 LEU A 382
ASP A 268
PRO A 269
ARG A 270
 None
 0.98A 6fgdA-3ejnA:
undetectable		 6fgdA-3ejnA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fii BOTULINUM NEUROTOXIN
TYPE F

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 380
ASP A 220
PRO A 221
ARG A  97
 None
 0.96A 6fgdA-3fiiA:
1.7		 6fgdA-3fiiA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxg RHAMNONATE
DEHYDRATASE

(Fusarium
graminearum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 143
ASP A 104
PRO A 105
ARG A 106
 None
 1.20A 6fgdA-3fxgA:
undetectable		 6fgdA-3fxgA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g05 TRNA URIDINE
5-CARBOXYMETHYLAMINO
METHYL MODIFICATION
ENZYME MNMG

(Escherichia
coli) 		PF01134
(GIDA)
PF13932
(GIDA_assoc) 		4 LEU A 417
ASP A 349
PRO A 350
ARG A 351
 None
 1.30A 6fgdA-3g05A:
3.2		 6fgdA-3g05A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g69 SORTASE C

(Streptococcus
pneumoniae) 		PF04203
(Sortase) 		4 LEU A 219
ASP A  86
PRO A  87
ARG A 230
 None
 1.02A 6fgdA-3g69A:
undetectable		 6fgdA-3g69A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igs N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE 2

(Salmonella
enterica) 		PF04131
(NanE) 		4 LEU A  77
ASP A  90
PRO A  86
ARG A  75
 None
None
None
SO4  A 236 ( 3.0A)
 1.32A 6fgdA-3igsA:
undetectable		 6fgdA-3igsA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ij3 CYTOSOL
AMINOPEPTIDASE

(Coxiella
burnetii) 		PF00883
(Peptidase_M17) 		4 LEU A 235
ASP A 292
PRO A 290
ARG A 289
 None
 1.19A 6fgdA-3ij3A:
undetectable		 6fgdA-3ij3A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k3q BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU B  94
ASP B 216
PRO B 217
ARG B  97
 None
 1.43A 6fgdA-3k3qB:
2.3		 6fgdA-3k3qB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE

(Pseudomonas
aeruginosa) 		PF01979
(Amidohydro_1) 		4 LEU A 186
ASP A 133
PRO A 134
ARG A 189
 None
 1.33A 6fgdA-3mduA:
undetectable		 6fgdA-3mduA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o0p SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		4 LEU A 217
ASP A  84
PRO A  85
ARG A 228
 None
 1.20A 6fgdA-3o0pA:
undetectable		 6fgdA-3o0pA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxu PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Burkholderia
pseudomallei) 		PF01467
(CTP_transf_like) 		4 LEU A 153
ASP A  11
PRO A  12
ARG A 132
 None
None
None
SO4  A 205 ( 4.9A)
 1.31A 6fgdA-3pxuA:
2.9		 6fgdA-3pxuA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qc2 GLYCOSYL HYDROLASE

(Bacteroides
ovatus) 		PF04041
(Glyco_hydro_130) 		4 LEU A 108
ASP A 145
PRO A 146
ARG A  92
 None
 1.08A 6fgdA-3qc2A:
undetectable		 6fgdA-3qc2A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r67 PUTATIVE GLYCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF04041
(Glyco_hydro_130) 		4 LEU A 105
ASP A 142
PRO A 143
ARG A  89
 None
EDO  A 382 ( 4.7A)
None
None
 1.10A 6fgdA-3r67A:
undetectable		 6fgdA-3r67A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE

(Parabacteroides
distasonis) 		PF04041
(Glyco_hydro_130) 		4 LEU A 113
ASP A 150
PRO A 151
ARG A  97
 None
 1.09A 6fgdA-3tawA:
undetectable		 6fgdA-3tawA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4y UNCHARACTERIZED
PROTEIN

(Desulfotomaculum
acetoxidans) 		PF10282
(Lactonase) 		4 LEU A 192
ASP A 265
PRO A 266
ARG A 267
 None
 0.88A 6fgdA-3u4yA:
undetectable		 6fgdA-3u4yA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0a NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		4 LEU B  85
ASP B 217
PRO B 218
ARG B  88
 None
 1.42A 6fgdA-3v0aB:
2.2		 6fgdA-3v0aB:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvo CRISPR-ASSOCIATED
PROTEIN, CSE1 FAMILY

(Thermobifida
fusca) 		PF09481
(CRISPR_Cse1) 		4 LEU A 288
ASP A 259
PRO A 254
ARG A 253
 None
 1.31A 6fgdA-3wvoA:
undetectable		 6fgdA-3wvoA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF01467
(CTP_transf_like) 		4 LEU A 153
ASP A  11
PRO A  12
ARG A 132
 None
None
None
ACO  A 201 ( 4.1A)
 1.24A 6fgdA-3x1jA:
2.8		 6fgdA-3x1jA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CMR4

(Archaeoglobus
fulgidus) 		PF03787
(RAMPs) 		4 LEU C  63
ASP C 101
PRO C 102
ARG C  59
 None
None
None
G  I   8 ( 4.9A)
 1.18A 6fgdA-3x1lC:
undetectable		 6fgdA-3x1lC:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zus BOTULINUM NEUROTOXIN
TYPE A,
SYNAPTOSOMAL-ASSOCIA
TED PROTEIN 23

(Clostridium
botulinum;
Homo sapiens) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		4 LEU A  94
ASP A 216
PRO A 217
ARG A  97
 None
 1.41A 6fgdA-3zusA:
undetectable		 6fgdA-3zusA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmn INOSITOL
POLYPHOSPHATE
5-PHOSPHATASE OCRL-1

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 LEU A 530
ASP A 270
PRO A 269
ARG A 241
 None
 1.39A 6fgdA-4cmnA:
undetectable		 6fgdA-4cmnA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpg LYSINE--TRNA LIGASE

(Homo sapiens) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 LEU A 210
ASP A 180
PRO A 208
ARG A  80
 None
 1.42A 6fgdA-4dpgA:
undetectable		 6fgdA-4dpgA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1h SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		4 LEU A 216
ASP A  84
PRO A  85
ARG A 227
 None
 1.19A 6fgdA-4g1hA:
undetectable		 6fgdA-4g1hA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1j SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		4 LEU A 223
ASP A  90
PRO A  91
ARG A 234
 None
 1.29A 6fgdA-4g1jA:
undetectable		 6fgdA-4g1jA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gni PUTATIVE HEAT SHOCK
PROTEIN

(Chaetomium
thermophilum) 		PF00012
(HSP70) 		4 LEU A 277
ASP A 266
PRO A 267
ARG A 268
 None
 1.28A 6fgdA-4gniA:
1.8		 6fgdA-4gniA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 LEU A 192
ASP A 429
PRO A 187
ARG A 221
 None
 1.37A 6fgdA-4gysA:
undetectable		 6fgdA-4gysA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ita SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Synechococcus
sp. PCC 7002) 		PF00171
(Aldedh) 		4 LEU A  89
ASP A 420
PRO A 421
ARG A 422
 None
 1.15A 6fgdA-4itaA:
2.9		 6fgdA-4itaA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ler PUTATIVE OUTER
MEMBRANE PROTEIN,
PROBABLY INVOLVED IN
NUTRIENT BINDING

(Bacteroides
vulgatus) 		PF12771
(SusD-like_2) 		4 LEU A 387
ASP A 273
PRO A 274
ARG A 275
 None
 0.92A 6fgdA-4lerA:
undetectable		 6fgdA-4lerA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ph0 BLV CAPSID

(Bovine leukemia
virus) 		PF00607
(Gag_p24) 		4 LEU A  54
ASP A  48
PRO A  49
ARG A 110
 None
 1.29A 6fgdA-4ph0A:
undetectable		 6fgdA-4ph0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qor CATALASE

(Bacillus
pumilus) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 LEU A 332
ASP A 280
PRO A 281
ARG A 138
 HEM  A 502 ( 4.2A)
None
None
None
 1.14A 6fgdA-4qorA:
undetectable		 6fgdA-4qorA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsz MALTOSE-BINDING
PERIPLASMIC PROTEIN,
JMJC
DOMAIN-CONTAINING
PROTEIN 7 CHIMERA

(Escherichia
coli;
Mus musculus) 		PF13416
(SBP_bac_8)
PF13621
(Cupin_8) 		4 LEU A 259
ASP A 202
PRO A 199
ARG A  21
 None
 1.20A 6fgdA-4qszA:
undetectable		 6fgdA-4qszA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1p L-ARABINOSE
ISOMERASE

(Geobacillus
kaustophilus) 		PF02610
(Arabinose_Isome)
PF11762
(Arabinose_Iso_C) 		4 LEU A 426
ASP A 383
PRO A 413
ARG A 424
 None
 1.38A 6fgdA-4r1pA:
5.7		 6fgdA-4r1pA:
21.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4u90 GEPHYRIN

(Rattus
norvegicus) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 LEU A 334
ASP A 651
PRO A 652
ARG A 653
 None
 0.28A 6fgdA-4u90A:
50.7		 6fgdA-4u90A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0i 4-AMINOBUTYRATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Sus scrofa) 		PF00202
(Aminotran_3) 		4 LEU A 103
ASP A 357
PRO A 358
ARG A 100
 None
 1.30A 6fgdA-4y0iA:
undetectable		 6fgdA-4y0iA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BOTULINUM NEUROTOXIN
TYPE E,
NONTOXIC-NONHEMAGGLU
TININ COMPONENT,
NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		4 LEU B  85
ASP B 184
PRO B 185
ARG B  88
 None
 1.43A 6fgdA-4zktB:
undetectable		 6fgdA-4zktB:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED

(Bacteroides
thetaiotaomicron) 		PF04041
(Glyco_hydro_130) 		4 LEU B 105
ASP B 142
PRO B 143
ARG B  89
 None
MAN  B1386 (-3.1A)
None
MAN  B1485 ( 2.7A)
 1.10A 6fgdA-5a7vB:
undetectable		 6fgdA-5a7vB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ayd BETA-1,4-MANNOOLIGOS
ACCHARIDE
PHOSPHORYLASE

(Ruminococcus
albus) 		PF04041
(Glyco_hydro_130) 		4 LEU A  77
ASP A 115
PRO A 116
ARG A  67
 None
 1.22A 6fgdA-5aydA:
undetectable		 6fgdA-5aydA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cnx AMINOPEPTIDASE YPDF

(Escherichia
coli) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 LEU A 318
ASP A 301
PRO A 302
ARG A 303
 None
 0.98A 6fgdA-5cnxA:
undetectable		 6fgdA-5cnxA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dkx ALPHA
GLUCOSIDASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110) 		4 LEU A 769
ASP A 787
PRO A 786
ARG A 822
 None
 1.11A 6fgdA-5dkxA:
undetectable		 6fgdA-5dkxA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ds0 PEPTIDASE M42

(Thaumarchaeota
archaeon SCGC
AB-539-E09) 		PF05343
(Peptidase_M42) 		4 LEU A 352
ASP A 231
PRO A  59
ARG A  58
 None
 1.44A 6fgdA-5ds0A:
3.3		 6fgdA-5ds0A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3x THERMOSTABLE
CARBOXYPEPTIDASE 1

(Fervidobacterium
islandicum) 		PF02074
(Peptidase_M32) 		4 LEU A 322
ASP A 186
PRO A 187
ARG A 245
 None
 1.23A 6fgdA-5e3xA:
undetectable		 6fgdA-5e3xA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hgq LYSINE--TRNA LIGASE

(Loa loa) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 LEU A 142
ASP A 112
PRO A 140
ARG A  12
 None
 1.36A 6fgdA-5hgqA:
undetectable		 6fgdA-5hgqA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp0 BETA-GLUCOSIDASE
BOGH3B

(Bacteroides
ovatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 LEU A 542
ASP A 189
PRO A 190
ARG A 191
 None
 1.22A 6fgdA-5jp0A:
3.0		 6fgdA-5jp0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jp0 BETA-GLUCOSIDASE
BOGH3B

(Bacteroides
ovatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 LEU A 623
ASP A 189
PRO A 190
ARG A 191
 None
 1.00A 6fgdA-5jp0A:
3.0		 6fgdA-5jp0A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kwl VP3

(Enterovirus C) 		PF00073
(Rhv) 		4 LEU 3  57
ASP 3  92
PRO 3  93
ARG 3  94
 None
 1.39A 6fgdA-5kwl3:
undetectable		 6fgdA-5kwl3:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5llt NICOTINATE-NUCLEOTID
E
ADENYLYLTRANSFERASE

(Plasmodium
falciparum) 		PF01467
(CTP_transf_like) 		4 LEU A 175
ASP A  14
PRO A  15
ARG A 172
 None
 1.36A 6fgdA-5lltA:
2.5		 6fgdA-5lltA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb9 PUTATIVE HEAT SHOCK
PROTEIN

(Chaetomium
thermophilum) 		PF00012
(HSP70) 		4 LEU A 277
ASP A 266
PRO A 267
ARG A 268
 None
 1.27A 6fgdA-5mb9A:
undetectable		 6fgdA-5mb9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n3u PHYCOCYANOBILIN
LYASE SUBUNIT BETA

(Nostoc sp. PCC
7120) 		no annotation 4 LEU B 126
ASP B  91
PRO B  92
ARG B  93
 None
 0.64A 6fgdA-5n3uB:
undetectable		 6fgdA-5n3uB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o64 REACTION CENTER
PROTEIN H CHAIN

(Blastochloris
viridis) 		PF03967
(PRCH)
PF05239
(PRC) 		4 LEU H 183
ASP H 151
PRO H 152
ARG H 153
 None
 1.13A 6fgdA-5o64H:
undetectable		 6fgdA-5o64H:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN

(Bacteroides
intestinalis) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 LEU A 532
ASP A 165
PRO A 166
ARG A 167
 None
 0.93A 6fgdA-5tf0A:
3.2		 6fgdA-5tf0A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2a AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Brucella canis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 146
ASP A 175
PRO A 172
ARG A 149
 None
 1.39A 6fgdA-5u2aA:
4.6		 6fgdA-5u2aA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2a AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Brucella canis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 269
ASP A 246
PRO A 247
ARG A 100
 None
 1.43A 6fgdA-5u2aA:
4.6		 6fgdA-5u2aA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uju NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Burkholderia
multivorans) 		PF00171
(Aldedh) 		4 LEU A 276
ASP A  90
PRO A  89
ARG A 279
 None
 1.43A 6fgdA-5ujuA:
4.6		 6fgdA-5ujuA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x4j UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		no annotation 4 LEU A 300
ASP A 289
PRO A 290
ARG A 291
 None
 1.15A 6fgdA-5x4jA:
5.5		 6fgdA-5x4jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 LEU A 530
ASP A 163
PRO A 164
ARG A 165
 None
 0.95A 6fgdA-5xxoA:
3.1		 6fgdA-5xxoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ylv POTASSIUM-TRANSPORTI
NG ATPASE SUBUNIT
BETA

(Sus scrofa) 		no annotation 4 LEU B 113
ASP B  87
PRO B  86
ARG B  85
 None
 1.25A 6fgdA-5ylvB:
undetectable		 6fgdA-5ylvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b2v SORB

(Sorangium
cellulosum) 		no annotation 4 LEU A 180
ASP A 219
PRO A 220
ARG A 221
 None
 1.12A 6fgdA-6b2vA:
undetectable		 6fgdA-6b2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b2v SORB

(Sorangium
cellulosum) 		no annotation 4 LEU A 184
ASP A 219
PRO A 220
ARG A 221
 None
 1.26A 6fgdA-6b2vA:
undetectable		 6fgdA-6b2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 4 LEU A 438
ASP A 488
PRO A 489
ARG A 490
 None
 0.95A 6fgdA-6bogA:
undetectable		 6fgdA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c29 PUTATIVE METAL
RESISTANCE PROTEIN

(Proteus
mirabilis) 		no annotation 4 LEU A 205
ASP A 233
PRO A 181
ARG A 173
 None
 1.35A 6fgdA-6c29A:
undetectable		 6fgdA-6c29A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eic MYCOBACTERIUM
TUBERCULOSIS
MONOGLYCERIDE LIPASE

(Mycobacterium
tuberculosis) 		no annotation 4 LEU C 129
ASP C 245
PRO C 217
ARG C 278
 None
 1.29A 6fgdA-6eicC:
3.6		 6fgdA-6eicC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8l -

(-) 		no annotation 4 LEU G 388
ASP G 434
PRO G 435
ARG G 436
 None
 0.73A 6fgdA-6f8lG:
undetectable		 6fgdA-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g72 NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT 8
NADH DEHYDROGENASE
[UBIQUINONE] 1 ALPHA
SUBCOMPLEX SUBUNIT
13

(Mus musculus;
Mus musculus) 		no annotation
no annotation 		4 LEU Z  83
ASP X  51
PRO X  52
ARG X  53
 None
 1.16A 6fgdA-6g72Z:
undetectable		 6fgdA-6g72Z:
undetectable