SIMILAR PATTERNS OF AMINO ACIDS FOR 6FGD_A_ACTA806_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4x PROTEIN
(2-HYDROXY-6-OXO-6-P
HENYLHEXA-2,4-DIENOA
TE HYDROLASE)

(Rhodococcus
jostii) 		PF12697
(Abhydrolase_6) 		4 MET A 111
GLY A  36
HIS A  35
GLY A 112
 None
 1.34A 6fgdA-1c4xA:
2.9		 6fgdA-1c4xA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jjf ENDO-1,4-BETA-XYLANA
SE Z

(Ruminiclostridium
thermocellum) 		PF00756
(Esterase) 		4 MET A 173
GLY A  89
HIS A  88
GLY A 174
 PT  A 288 (-2.7A)
None
None
None
 1.46A 6fgdA-1jjfA:
2.1		 6fgdA-1jjfA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 MET A 269
GLY A 268
HIS A 276
GLY A 270
 None
None
CU  A1049 ( 3.1A)
None
 1.37A 6fgdA-1kcwA:
undetectable		 6fgdA-1kcwA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5t DIHYDRODIPICOLINATE
SYNTHASE

(Escherichia
coli) 		PF00701
(DHDPS) 		4 MET A 195
GLY A 199
HIS A 200
GLY A 201
 None
 1.01A 6fgdA-1s5tA:
undetectable		 6fgdA-1s5tA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v7v CHITOBIOSE
PHOSPHORYLASE

(Vibrio
proteolyticus) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 MET A 693
GLY A 694
HIS A 612
GLY A 634
 None
 1.47A 6fgdA-1v7vA:
undetectable		 6fgdA-1v7vA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvg CDP-GLUCOSE
4,6-DEHYDRATASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		4 MET A  89
GLY A  18
HIS A  19
GLY A  24
 APR  A 400 (-4.9A)
APR  A 400 (-3.2A)
None
None
 1.23A 6fgdA-1wvgA:
1.6		 6fgdA-1wvgA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zef ALKALINE PHOSPHATASE

(Homo sapiens) 		PF00245
(Alk_phosphatase) 		4 MET A  44
GLY A  43
HIS A 358
GLY A  45
 None
ZN  A 902 ( 4.9A)
ZN  A 902 (-3.2A)
None
 1.34A 6fgdA-1zefA:
undetectable		 6fgdA-1zefA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1w ENDOU PROTEIN

(Xenopus laevis) 		PF09412
(XendoU) 		4 MET A 175
GLY A 176
HIS A 178
GLY A 166
 None
 1.36A 6fgdA-2c1wA:
undetectable		 6fgdA-2c1wA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cuk GLYCERATE
DEHYDROGENASE/GLYOXY
LATE REDUCTASE

(Thermus
thermophilus) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 MET A 152
GLY A 156
HIS A 200
GLY A 151
 None
 1.43A 6fgdA-2cukA:
3.7		 6fgdA-2cukA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qxt LIPASE

(Bacillus
subtilis) 		PF01674
(Lipase_2) 		4 MET A  78
GLY A  11
HIS A  10
GLY A  79
 None
 1.30A 6fgdA-2qxtA:
5.4		 6fgdA-2qxtA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x98 ALKALINE PHOSPHATASE

(Halobacterium
salinarum) 		PF00245
(Alk_phosphatase) 		4 MET A  58
GLY A  57
HIS A 347
GLY A  59
 None
None
ZN  A1476 ( 3.1A)
None
 1.36A 6fgdA-2x98A:
undetectable		 6fgdA-2x98A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x98 ALKALINE PHOSPHATASE

(Halobacterium
salinarum) 		PF00245
(Alk_phosphatase) 		4 MET A  58
GLY A  57
HIS A 347
GLY A 345
 None
None
ZN  A1476 ( 3.1A)
None
 0.99A 6fgdA-2x98A:
undetectable		 6fgdA-2x98A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE

(Escherichia
coli) 		PF01380
(SIS) 		4 MET A  57
GLY A  58
HIS A  62
GLY A  56
 None
 1.12A 6fgdA-2xhzA:
3.3		 6fgdA-2xhzA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a52 COLD-ACTIVE ALKALINE
PHOSPHATASE

(Shewanella sp.
AP1) 		PF00245
(Alk_phosphatase) 		4 MET A  11
GLY A  10
HIS A 270
GLY A   8
 None
None
ZN  A1001 (-4.8A)
None
 1.42A 6fgdA-3a52A:
2.5		 6fgdA-3a52A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a52 COLD-ACTIVE ALKALINE
PHOSPHATASE

(Shewanella sp.
AP1) 		PF00245
(Alk_phosphatase) 		4 MET A  11
GLY A  10
HIS A 270
GLY A  12
 None
None
ZN  A1001 (-4.8A)
None
 1.40A 6fgdA-3a52A:
2.5		 6fgdA-3a52A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b5q PUTATIVE SULFATASE
YIDJ

(Bacteroides
thetaiotaomicron) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 MET A 304
GLY A 285
HIS A  25
GLY A 287
 None
 1.18A 6fgdA-3b5qA:
undetectable		 6fgdA-3b5qA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 MET A 553
GLY A 554
HIS A 627
GLY A 616
 None
 1.40A 6fgdA-3bgaA:
undetectable		 6fgdA-3bgaA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cai POSSIBLE
AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00266
(Aminotran_5) 		4 MET A  28
GLY A  27
HIS A 218
GLY A 221
 None
 1.13A 6fgdA-3caiA:
undetectable		 6fgdA-3caiA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2d ALKALINE PHOSPHATASE

(Vibrio sp.
G15-21) 		PF00245
(Alk_phosphatase) 		4 MET A  14
GLY A  13
HIS A 316
GLY A  15
 None
None
ZN  A 602 ( 3.2A)
None
 1.34A 6fgdA-3e2dA:
undetectable		 6fgdA-3e2dA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flu DIHYDRODIPICOLINATE
SYNTHASE

(Neisseria
meningitidis) 		PF00701
(DHDPS) 		4 MET A 195
GLY A 199
HIS A 200
GLY A 201
 None
 1.00A 6fgdA-3fluA:
undetectable		 6fgdA-3fluA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		4 MET A 114
GLY A 113
HIS A 111
GLY A 127
 None
 1.48A 6fgdA-3k30A:
4.7		 6fgdA-3k30A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxy 4-HYDROXYTHREONINE-4
-PHOSPHATE
DEHYDROGENASE

(Yersinia pestis) 		PF04166
(PdxA) 		4 MET A 219
GLY A 220
HIS A 221
GLY A 214
 None
 1.46A 6fgdA-3lxyA:
undetectable		 6fgdA-3lxyA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdb KINESIN-LIKE PROTEIN
KIF13B

(Homo sapiens) 		PF00498
(FHA) 		4 MET A 486
GLY A 485
HIS A 538
GLY A 487
 None
UNX  A   1 ( 3.8A)
None
None
 1.45A 6fgdA-3mdbA:
undetectable		 6fgdA-3mdbA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4s FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 MET A 213
GLY A 214
HIS A 510
GLY A 210
 None
 1.28A 6fgdA-3p4sA:
2.7		 6fgdA-3p4sA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pko GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE

(Lactobacillus
brevis) 		PF00348
(polyprenyl_synt) 		4 MET A 118
GLY A 115
HIS A  86
GLY A  82
 None
 1.25A 6fgdA-3pkoA:
undetectable		 6fgdA-3pkoA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0z D-SERINE DEHYDRATASE

(Salmonella
enterica) 		PF00291
(PALP) 		4 MET A 426
GLY A 425
HIS A 108
GLY A 113
 None
None
EDO  A 452 (-3.9A)
None
 0.97A 6fgdA-3r0zA:
undetectable		 6fgdA-3r0zA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ss7 D-SERINE DEHYDRATASE

(Escherichia
coli) 		PF00291
(PALP) 		4 MET X 428
GLY X 427
HIS X 110
GLY X 115
 None
 0.94A 6fgdA-3ss7X:
undetectable		 6fgdA-3ss7X:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t2y SULFIDE-QUINONE
REDUCTASE, PUTATIVE

(Acidithiobacillus
ferrooxidans) 		PF07992
(Pyr_redox_2) 		4 MET A 360
GLY A 361
HIS A 388
GLY A 364
 LMT  A 501 ( 3.7A)
None
None
None
 0.96A 6fgdA-3t2yA:
4.8		 6fgdA-3t2yA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttf TRANSCRIPTIONAL
REGULATORY PROTEIN

(Escherichia
coli) 		PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 MET A 506
GLY A 505
HIS A 476
GLY A 507
 None
 1.20A 6fgdA-3ttfA:
2.5		 6fgdA-3ttfA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v9a ESTERASE/LIPASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		4 MET A  80
GLY A  81
HIS A  74
GLY A  76
 None
 1.48A 6fgdA-3v9aA:
3.2		 6fgdA-3v9aA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbh ALKALINE PHOSPHATASE

(Halomonas sp.
#593) 		PF00245
(Alk_phosphatase) 		4 MET A  14
GLY A  13
HIS A 312
GLY A  11
 None
None
ZN  A 505 (-3.1A)
None
 1.43A 6fgdA-3wbhA:
undetectable		 6fgdA-3wbhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbh ALKALINE PHOSPHATASE

(Halomonas sp.
#593) 		PF00245
(Alk_phosphatase) 		4 MET A  14
GLY A  13
HIS A 312
GLY A  15
 None
None
ZN  A 505 (-3.1A)
None
 1.37A 6fgdA-3wbhA:
undetectable		 6fgdA-3wbhA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gc5 DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL

(Mus musculus) 		PF00398
(RrnaAD) 		4 MET A 266
GLY A 265
HIS A 261
GLY A 263
 None
 1.25A 6fgdA-4gc5A:
undetectable		 6fgdA-4gc5A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krf PROTEIN ARGONAUTE-1

(Homo sapiens) 		PF02170
(PAZ)
PF02171
(Piwi)
PF08699
(ArgoL1)
PF16486
(ArgoN)
PF16487
(ArgoMid)
PF16488
(ArgoL2) 		4 MET A 540
GLY A 539
HIS A 847
GLY A 534
 None
 1.41A 6fgdA-4krfA:
5.2		 6fgdA-4krfA:
19.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4u90 GEPHYRIN

(Rattus
norvegicus) 		PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C) 		4 MET A 351
GLY A 352
HIS A 476
GLY A 478
 None
 0.22A 6fgdA-4u90A:
50.7		 6fgdA-4u90A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uob ENDONUCLEASE III-3

(Deinococcus
radiodurans) 		PF00730
(HhH-GPD) 		4 MET A 252
GLY A 297
HIS A 296
GLY A 293
 None
None
SF4  A1329 ( 4.7A)
None
 1.44A 6fgdA-4uobA:
undetectable		 6fgdA-4uobA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzn GENOME POLYPROTEIN

(Hepatovirus A) 		no annotation 4 MET A 929
GLY A 928
HIS A 927
GLY A 889
 None
 1.42A 6fgdA-4wznA:
undetectable		 6fgdA-4wznA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xeu TRANSKETOLASE

(Pseudomonas
aeruginosa) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 MET A  31
GLY A  28
HIS A  26
GLY A 247
 None
 1.42A 6fgdA-4xeuA:
3.7		 6fgdA-4xeuA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8z UNCHARACTERIZED
PROTEIN

(Ruminiclostridium
thermocellum) 		no annotation 4 MET A 188
GLY A 101
HIS A 100
GLY A 189
 None
 1.27A 6fgdA-4z8zA:
3.8		 6fgdA-4z8zA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoy SQT1

(Chaetomium
thermophilum) 		PF00400
(WD40) 		4 MET A 450
GLY A 506
HIS A 498
GLY A 449
 None
 1.48A 6fgdA-4zoyA:
undetectable		 6fgdA-4zoyA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zrs ESTERASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		4 MET A  79
GLY A  80
HIS A  73
GLY A  75
 None
None
None
SEB  A 151 ( 3.8A)
 1.45A 6fgdA-4zrsA:
3.7		 6fgdA-4zrsA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b5z PTLCIB4 H88A MUTANT

(Phaeodactylum
tricornutum) 		no annotation 4 MET A  85
GLY A  83
HIS A 218
GLY A  87
 None
 1.41A 6fgdA-5b5zA:
undetectable		 6fgdA-5b5zA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxu FERULIC ACID
ESTERASE AMCE1/FAE1A

(Anaeromyces
mucronatus) 		PF00756
(Esterase) 		4 MET A 157
GLY A  64
HIS A  63
GLY A 158
 None
 1.38A 6fgdA-5cxuA:
undetectable		 6fgdA-5cxuA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e5d PEPTIDE DEFORMYLASE

(Xanthomonas
oryzae) 		PF01327
(Pep_deformylase) 		4 MET A  39
GLY A  40
HIS A  43
GLY A  44
 None
 1.05A 6fgdA-5e5dA:
undetectable		 6fgdA-5e5dA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ie6 ZEARALENONE
HYDROLASE

(Clonostachys
rosea) 		PF00561
(Abhydrolase_1) 		4 MET A 241
GLY A 240
HIS A 248
GLY A 160
 None
 0.91A 6fgdA-5ie6A:
3.0		 6fgdA-5ie6A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcn UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF12146
(Hydrolase_4) 		4 MET A 150
GLY A  74
HIS A  73
GLY A 151
 None
 1.46A 6fgdA-5lcnA:
3.6		 6fgdA-5lcnA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4c PROLYL
OLIGOPEPTIDASE

(Galerina
marginata) 		no annotation 4 MET A 700
GLY A 699
HIS A 698
GLY A 697
 None
 0.86A 6fgdA-5n4cA:
3.7		 6fgdA-5n4cA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n5n TUBULIN BETA CHAIN

(Homo sapiens) 		no annotation 4 MET B 149
GLY B 148
HIS B 107
GLY B 111
 None
 1.18A 6fgdA-5n5nB:
undetectable		 6fgdA-5n5nB:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9e HTH-TYPE
TRANSCRIPTIONAL
ACTIVATOR RHAR

(Bacteria
Latreille et
al. 1825) 		no annotation 4 MET A 123
GLY A 122
HIS A 162
GLY A 119
 None
 1.31A 6fgdA-5u9eA:
undetectable		 6fgdA-5u9eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE

(Pseudomonas
aeruginosa) 		no annotation 4 MET A  48
GLY A  49
HIS A  77
GLY A  43
 AMP  A 304 (-4.9A)
None
None
None
 1.49A 6fgdA-5zbkA:
2.5		 6fgdA-5zbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbl CYTOKININ RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE

(Corynebacterium
glutamicum) 		no annotation 4 MET A  55
GLY A  56
HIS A  84
GLY A  50
 None
 1.46A 6fgdA-5zblA:
3.1		 6fgdA-5zblA:
undetectable