SIMILAR PATTERNS OF AMINO ACIDS FOR 6FBV_D_FI8D1904_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ayz UBIQUITIN-CONJUGATIN
G ENZYME RAD6

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 MET A  39
ILE A  40
VAL A  35
GLU A  58
 None
 1.17A 6fbvC-1ayzA:
0.7		 6fbvC-1ayzA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0z PROTEIN
(PHOSPHOGLUCOSE
ISOMERASE)

(Geobacillus
stearothermophilus) 		PF00342
(PGI) 		4 ILE A 199
THR A 173
VAL A 172
SER A 140
 None
 0.98A 6fbvC-1b0zA:
0.0		 6fbvC-1b0zA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1btn BETA-SPECTRIN

(Mus musculus) 		PF15410
(PH_9) 		4 MET A  96
ILE A 100
VAL A  26
LYS A  39
 None
 1.15A 6fbvC-1btnA:
0.0		 6fbvC-1btnA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d6h CHALCONE SYNTHASE

(Medicago sativa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 ILE A 246
GLN A 244
THR A 169
VAL A 170
 None
 0.90A 6fbvC-1d6hA:
0.0		 6fbvC-1d6hA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ds9 OUTER ARM DYNEIN

(Chlamydomonas
reinhardtii) 		PF12799
(LRR_4) 		4 MET A  33
ILE A  34
VAL A  21
GLU A  15
 None
 1.08A 6fbvC-1ds9A:
0.0		 6fbvC-1ds9A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e59 PHOSPHOGLYCERATE
MUTASE

(Escherichia
coli) 		PF00300
(His_Phos_1) 		4 ILE A 179
THR A   3
VAL A   2
GLU A 216
 None
 1.02A 6fbvC-1e59A:
undetectable		 6fbvC-1e59A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fl2 ALKYL HYDROPEROXIDE
REDUCTASE SUBUNIT F

(Escherichia
coli) 		PF07992
(Pyr_redox_2) 		4 ILE A 498
THR A 252
VAL A 253
GLU A 265
 None
FAD  A 522 (-3.5A)
None
None
 1.07A 6fbvC-1fl2A:
0.0		 6fbvC-1fl2A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ftp MUSCLE FATTY ACID
BINDING PROTEIN

(Schistocerca
gregaria) 		PF00061
(Lipocalin) 		4 THR A  87
VAL A  95
LYS A  93
SER A  84
 None
 1.13A 6fbvC-1ftpA:
2.1		 6fbvC-1ftpA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus) 		PF01896
(DNA_primase_S) 		4 ILE A 131
THR A 284
VAL A 285
GLU A 168
 None
 1.14A 6fbvC-1g71A:
0.0		 6fbvC-1g71A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltd FLAVOCYTOCHROME B2

(Saccharomyces
cerevisiae) 		PF00173
(Cyt-b5)
PF01070
(FMN_dh) 		4 ILE A 227
GLN A 252
THR A 280
VAL A 281
 None
FMN  A 570 (-3.0A)
FMN  A 570 (-3.3A)
None
 0.96A 6fbvC-1ltdA:
undetectable		 6fbvC-1ltdA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mty METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylococcus
capsulatus) 		PF02964
(MeMO_Hyd_G) 		4 ILE G 122
THR G  94
VAL G  95
SER G  89
 None
 1.06A 6fbvC-1mtyG:
undetectable		 6fbvC-1mtyG:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pk6 COMPLEMENT C1Q
SUBCOMPONENT, A
CHAIN PRECURSOR
COMPLEMENT C1Q
SUBCOMPONENT, C
CHAIN PRECURSOR

(Homo sapiens;
Homo sapiens) 		PF00386
(C1q)
PF00386
(C1q) 		4 GLN A 177
THR A 171
LYS C 170
GLU A 148
 CA  B   1 (-3.2A)
None
None
None
 0.98A 6fbvC-1pk6A:
undetectable		 6fbvC-1pk6A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qcw FLAVOCYTOCHROME B2

(Saccharomyces
cerevisiae) 		PF01070
(FMN_dh) 		4 ILE A 227
GLN A 252
THR A 280
VAL A 281
 None
FNS  A 570 (-3.3A)
FNS  A 570 (-2.8A)
None
 1.05A 6fbvC-1qcwA:
undetectable		 6fbvC-1qcwA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3t ALCOHOL
DEHYDROGENASE ALPHA
CHAIN

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ILE A 143
THR A  59
VAL A  58
SER A 117
 None
 1.10A 6fbvC-1u3tA:
undetectable		 6fbvC-1u3tA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1umf CHORISMATE SYNTHASE

(Helicobacter
pylori) 		PF01264
(Chorismate_synt) 		4 ILE A 248
VAL A 149
GLU A 151
SER A 152
 None
 0.90A 6fbvC-1umfA:
undetectable		 6fbvC-1umfA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v61 RAC/CDC42 GUANINE
NUCLEOTIDE EXCHANGE
FACTOR (GEF) 6

(Mus musculus) 		PF00169
(PH) 		4 MET A 118
GLN A 120
VAL A  28
SER A  54
 None
 1.17A 6fbvC-1v61A:
undetectable		 6fbvC-1v61A:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x25 HYPOTHETICAL UPF0076
PROTEIN ST0811

(Sulfurisphaera
tokodaii) 		PF01042
(Ribonuc_L-PSP) 		4 ILE A  57
VAL A  22
LYS A  -1
SER A 123
 None
 1.08A 6fbvC-1x25A:
undetectable		 6fbvC-1x25A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x2b PROLINE
IMINOPEPTIDASE

(Serratia
marcescens) 		PF00561
(Abhydrolase_1) 		4 THR A 207
VAL A 208
GLU A 204
SER A 201
 None
None
STX  A 401 (-3.1A)
None
 1.09A 6fbvC-1x2bA:
undetectable		 6fbvC-1x2bA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT

(Pseudomonas
putida) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		4 ILE A 392
GLN A 264
THR A 294
VAL A 304
 None
 1.15A 6fbvC-1z01A:
undetectable		 6fbvC-1z01A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6r MLC PROTEIN

(Escherichia
coli) 		PF00480
(ROK) 		4 ILE A 151
VAL A 110
GLU A 112
SER A 113
 None
 0.90A 6fbvC-1z6rA:
0.8		 6fbvC-1z6rA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a1d STAPHYLOCOAGULASE

(Staphylococcus
aureus) 		PF08764
(Coagulase) 		4 ILE D  39
GLN D  37
THR D 122
GLU D  69
 None
 1.09A 6fbvC-2a1dD:
undetectable		 6fbvC-2a1dD:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c08 SH3-CONTAINING
GRB2-LIKE PROTEIN 2

(Rattus
norvegicus) 		PF03114
(BAR) 		4 MET A 207
ILE A 209
THR A  43
VAL A  42
 None
 0.92A 6fbvC-2c08A:
undetectable		 6fbvC-2c08A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n3e MAJOR AMPULLATE
SPIDROIN 1

(Latrodectus
hesperus) 		PF16763
(Spidroin_N) 		4 ILE A  43
THR A  88
VAL A  87
SER A  27
 None
 0.98A 6fbvC-2n3eA:
undetectable		 6fbvC-2n3eA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oml RIBOSOMAL LARGE
SUBUNIT
PSEUDOURIDINE
SYNTHASE E

(Escherichia
coli) 		PF00849
(PseudoU_synth_2) 		4 ILE A 195
GLN A 112
THR A 165
GLU A 114
 None
 1.15A 6fbvC-2omlA:
undetectable		 6fbvC-2omlA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qc3 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Mycobacterium
tuberculosis) 		PF00698
(Acyl_transf_1) 		4 ILE A  95
GLN A  60
VAL A 189
SER A  11
 None
ACY  A 500 ( 4.7A)
None
None
 1.13A 6fbvC-2qc3A:
0.1		 6fbvC-2qc3A:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzi UNCHARACTERIZED
PROTEIN

(Streptococcus
thermophilus) 		PF08860
(DUF1827) 		4 ILE A  73
THR A  85
VAL A  86
GLU A  93
 None
 1.16A 6fbvC-2qziA:
undetectable		 6fbvC-2qziA:
6.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xd7 CORE HISTONE
MACRO-H2A.2

(Homo sapiens) 		PF01661
(Macro) 		4 ILE A 274
THR A 330
VAL A 329
GLU A 291
 None
 1.00A 6fbvC-2xd7A:
undetectable		 6fbvC-2xd7A:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yy8 UPF0106 PROTEIN
PH0461

(Pyrococcus
horikoshii) 		PF01994
(Trm56) 		4 ILE A  34
THR A  18
VAL A  17
GLU A 134
 None
None
None
MTA  A 400 (-4.0A)
 0.95A 6fbvC-2yy8A:
undetectable		 6fbvC-2yy8A:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0v SH3-CONTAINING
GRB2-LIKE PROTEIN 3

(Homo sapiens) 		PF03114
(BAR) 		4 ILE A 117
GLN A 114
THR A  50
VAL A  51
 None
 1.16A 6fbvC-2z0vA:
undetectable		 6fbvC-2z0vA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5r BENZALACETONE
SYNTHASE

(Rheum palmatum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 ILE A 239
GLN A 237
THR A 162
VAL A 163
 None
 0.89A 6fbvC-3a5rA:
0.2		 6fbvC-3a5rA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aux DNA DOUBLE-STRAND
BREAK REPAIR RAD50
ATPASE

(Methanocaldococcus
jannaschii) 		PF13476
(AAA_23) 		4 ILE A  27
THR A 949
VAL A 950
GLU A 947
 None
MG  A1050 (-3.0A)
None
None
 0.95A 6fbvC-3auxA:
undetectable		 6fbvC-3auxA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8v PUTATIVE
ACETYLTRANSFERASE

(Desulfovibrio
alaskensis) 		no annotation 4 ILE A 359
THR A 164
VAL A 165
SER A 161
 None
 1.17A 6fbvC-3c8vA:
undetectable		 6fbvC-3c8vA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e4f AMINOGLYCOSIDE
N3-ACETYLTRANSFERASE

(Bacillus
anthracis) 		PF02522
(Antibiotic_NAT) 		4 ILE A  65
THR A 144
VAL A 145
GLU A 141
 None
 1.02A 6fbvC-3e4fA:
undetectable		 6fbvC-3e4fA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebv CHINITASE A

(Streptomyces
coelicolor) 		PF00704
(Glyco_hydro_18) 		4 ILE A  80
THR A   8
VAL A   7
SER A 272
 None
 1.14A 6fbvC-3ebvA:
undetectable		 6fbvC-3ebvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Salmonella
enterica) 		PF00171
(Aldedh) 		4 THR A 209
VAL A 232
LYS A 230
GLU A 234
 None
None
None
NAD  A 463 (-4.1A)
 0.88A 6fbvC-3efvA:
undetectable		 6fbvC-3efvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gs9 PROTEIN GP18

(Listeria
monocytogenes) 		PF06605
(Prophage_tail) 		4 ILE A  17
VAL A  69
LYS A  71
GLU A  67
 None
None
None
MLY  A  12 ( 3.6A)
 1.14A 6fbvC-3gs9A:
undetectable		 6fbvC-3gs9A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm3 UNCHARACTERIZED
PROTEIN

(Parabacteroides
distasonis) 		PF12979
(DUF3863)
PF12980
(DUF3864) 		4 MET A 176
ILE A 175
GLU A  63
SER A  65
 None
 0.96A 6fbvC-3lm3A:
0.4		 6fbvC-3lm3A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lza PUTATIVE SNOAL-LIKE
POLYKETIDE CYCLASE

(Shewanella
denitrificans) 		PF12680
(SnoaL_2) 		4 ILE A  69
GLN A 141
THR A 127
VAL A 126
 None
 1.04A 6fbvC-3lzaA:
undetectable		 6fbvC-3lzaA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN

(Marinobacter
hydrocarbonoclasticus) 		PF04073
(tRNA_edit)
PF08668
(HDOD) 		4 MET A 253
ILE A 193
VAL A 222
SER A 216
 None
 1.09A 6fbvC-3memA:
undetectable		 6fbvC-3memA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA

(Vibrio cholerae) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 ILE B  23
GLN B 248
THR B 105
GLU B 108
 None
 1.17A 6fbvC-3o8qB:
undetectable		 6fbvC-3o8qB:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqn CATABOLITE CONTROL
PROTEIN A
PHOSPHOCARRIER
PROTEIN HPR

(Bacillus
subtilis;
Bacillus
subtilis) 		PF00356
(LacI)
PF13377
(Peripla_BP_3)
no annotation 		4 MET A 303
ILE A  83
THR S  20
VAL S  21
 None
 1.12A 6fbvC-3oqnA:
undetectable		 6fbvC-3oqnA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ot5 UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Listeria
monocytogenes) 		PF02350
(Epimerase_2) 		4 ILE A 364
THR A 176
GLU A 121
SER A 151
 None
 1.06A 6fbvC-3ot5A:
undetectable		 6fbvC-3ot5A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ozx RNASE L INHIBITOR

(Sulfolobus
solfataricus) 		PF00005
(ABC_tran) 		4 ILE A 522
THR A 513
VAL A 512
GLU A 369
 None
 1.05A 6fbvC-3ozxA:
undetectable		 6fbvC-3ozxA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pb0 DIHYDRODIPICOLINATE
SYNTHASE

(Thermotoga
maritima) 		PF00701
(DHDPS) 		4 GLN A 169
THR A 173
VAL A 174
LYS A 178
 None
 0.87A 6fbvC-3pb0A:
undetectable		 6fbvC-3pb0A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pbk FATTY ACYL-ADENYLATE
LIGASE

(Escherichia
coli) 		PF00501
(AMP-binding) 		4 GLN A 498
THR A 496
VAL A 495
GLU A 499
 None
 1.15A 6fbvC-3pbkA:
undetectable		 6fbvC-3pbkA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3phf ENVELOPE
GLYCOPROTEIN H

(Human
gammaherpesvirus
4) 		no annotation 4 THR A 326
VAL A 327
GLU A 324
SER A 321
 None
 1.08A 6fbvC-3phfA:
0.5		 6fbvC-3phfA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhi DNA-BINDING PROTEIN
HU

(Bacillus
anthracis) 		PF00216
(Bac_DNA_binding) 		4 GLN A  18
THR A  22
VAL A  23
GLU A  20
 None
 0.81A 6fbvC-3rhiA:
undetectable		 6fbvC-3rhiA:
6.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tzg HYPOTHETICAL PROTEIN
BVU_2266

(Bacteroides
vulgatus) 		no annotation 4 ILE A  72
THR A 118
VAL A 119
GLU A  98
 None
 1.16A 6fbvC-3tzgA:
undetectable		 6fbvC-3tzgA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v64 LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 4

(Rattus
norvegicus) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 ILE C 676
GLN C 674
VAL C 635
SER C 652
 None
 0.98A 6fbvC-3v64C:
undetectable		 6fbvC-3v64C:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vwc SERINE PROTEASE
INHIBITOR 1

(Coprinopsis
cinerea) 		PF16850
(Inhibitor_I66) 		4 GLN A  90
THR A  99
VAL A 100
SER A   2
 None
 1.15A 6fbvC-3vwcA:
undetectable		 6fbvC-3vwcA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdo MFS TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 ILE A 451
THR A 442
VAL A 441
GLU A 419
 None
 0.70A 6fbvC-3wdoA:
undetectable		 6fbvC-3wdoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cit VANADIUM-DEPENDENT
HALOPEROXIDASE

(Zobellia
galactanivorans) 		PF01569
(PAP2) 		4 ILE A 287
THR A  41
VAL A  40
SER A  55
 None
 1.05A 6fbvC-4citA:
0.0		 6fbvC-4citA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4duu PLASMINOGEN

(Homo sapiens) 		PF00024
(PAN_1)
PF00051
(Kringle)
PF00089
(Trypsin) 		4 ILE A 754
THR A 591
VAL A 577
SER A 594
 None
 1.13A 6fbvC-4duuA:
undetectable		 6fbvC-4duuA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1l ACETOACETYL-COA
THIOLASE 2

(Clostridioides
difficile) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 ILE A  71
THR A  83
VAL A  84
LYS A  86
 None
IOD  A 402 (-4.6A)
IOD  A 408 ( 4.6A)
IOD  A 408 (-3.4A)
 1.16A 6fbvC-4e1lA:
undetectable		 6fbvC-4e1lA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fuv PORIN PROTEIN
ASSOCIATED WITH
IMIPENEM RESISTANCE

(Acinetobacter
baumannii) 		no annotation 4 GLN A 125
THR A 188
VAL A 187
SER A 119
 None
 1.03A 6fbvC-4fuvA:
undetectable		 6fbvC-4fuvA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6x GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Catenulispora
acidiphila) 		PF00903
(Glyoxalase) 		4 ILE A 122
VAL A  28
GLU A  17
SER A  18
 None
 0.90A 6fbvC-4g6xA:
undetectable		 6fbvC-4g6xA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k2x POLYKETIDE
OXYGENASE/HYDROXYLAS
E

(Streptomyces
rimosus) 		PF01494
(FAD_binding_3) 		4 ILE A 338
GLN A 306
THR A  50
VAL A  51
 None
 0.97A 6fbvC-4k2xA:
undetectable		 6fbvC-4k2xA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m00 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		PF05345
(He_PIG) 		4 GLN A 565
THR A 497
LYS A 514
SER A 494
 None
 1.06A 6fbvC-4m00A:
undetectable		 6fbvC-4m00A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mla CYTOKININ OXIDASE 2

(Zea mays) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		4 GLN A 189
THR A 201
VAL A 200
SER A 208
 IPA  A 603 (-4.4A)
IPA  A 603 ( 4.5A)
None
None
 1.16A 6fbvC-4mlaA:
undetectable		 6fbvC-4mlaA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnm CHITINASE A

(Cycas revoluta) 		PF00704
(Glyco_hydro_18) 		4 ILE A 179
THR A 172
VAL A 171
GLU A 122
 EDO  A 401 ( 4.8A)
None
None
None
 1.17A 6fbvC-4mnmA:
undetectable		 6fbvC-4mnmA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ox9 16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE

(Escherichia
coli) 		PF02390
(Methyltransf_4) 		4 ILE Y 150
THR Y 139
VAL Y 138
SER Y 208
 None
 1.16A 6fbvC-4ox9Y:
undetectable		 6fbvC-4ox9Y:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2m MAJOR FACILITATOR
SUPERFAMILY MFS_1

(Escherichia
coli) 		no annotation 4 ILE A  64
THR A  55
VAL A  54
GLU A  32
 None
 1.10A 6fbvC-4q2mA:
undetectable		 6fbvC-4q2mA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8g PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Saccharomyces
cerevisiae) 		PF13423
(UCH_1) 		4 ILE A 722
THR A 666
VAL A 667
GLU A 653
 None
 1.03A 6fbvC-4q8gA:
undetectable		 6fbvC-4q8gA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q8h PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Saccharomyces
cerevisiae) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		4 ILE A 722
THR A 666
VAL A 667
GLU A 653
 None
 1.12A 6fbvC-4q8hA:
undetectable		 6fbvC-4q8hA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmj GLUCOSE-6-PHOSPHATE
ISOMERASE

(Colias
eurytheme) 		PF00342
(PGI) 		4 ILE A 157
THR A 172
VAL A 171
SER A 288
 None
 1.16A 6fbvC-4wmjA:
undetectable		 6fbvC-4wmjA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr7 PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Saccharomyces
cerevisiae) 		no annotation 4 ILE G 722
THR G 666
VAL G 667
GLU G 653
 None
 1.05A 6fbvC-4xr7G:
undetectable		 6fbvC-4xr7G:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zem TRANSLATION
INITIATION FACTOR
EIF2B-LIKE
PROTEIN,TRANSLATION
INITIATION FACTOR
EIF2B-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF01008
(IF-2B) 		4 ILE A 295
GLN A 214
GLU A 212
SER A 209
 None
 1.03A 6fbvC-4zemA:
undetectable		 6fbvC-4zemA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6g PORE DOMAIN OF
POTASSIUM CHANNEL
SUBFAMILY T MEMBER 1

(Gallus gallus) 		PF07885
(Ion_trans_2) 		4 MET B 313
ILE B 312
THR B 290
VAL B 289
 None
 0.89A 6fbvC-5a6gB:
undetectable		 6fbvC-5a6gB:
5.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b86 TUMOR NECROSIS
FACTOR ALPHA-INDUCED
PROTEIN 2

(Mus musculus) 		PF06046
(Sec6) 		4 GLN A 326
THR A 322
VAL A 321
GLU A 389
 None
 1.17A 6fbvC-5b86A:
undetectable		 6fbvC-5b86A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5caj UPF0246 PROTEIN YAAA

(Escherichia
coli) 		PF03883
(H2O2_YaaD) 		4 ILE A 133
VAL A 117
LYS A 154
SER A   6
 None
None
None
CL  A 301 (-3.3A)
 1.11A 6fbvC-5cajA:
undetectable		 6fbvC-5cajA:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cer BD0816

(Bdellovibrio
bacteriovorus) 		PF02113
(Peptidase_S13) 		4 ILE A 103
THR A  65
VAL A  62
SER A 278
 None
 0.93A 6fbvC-5cerA:
undetectable		 6fbvC-5cerA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dll AMINOPEPTIDASE N

(Francisella
tularensis) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		4 ILE A 379
THR A 386
VAL A 387
SER A 370
 None
 1.03A 6fbvC-5dllA:
undetectable		 6fbvC-5dllA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3t PHOSPHATIDYLINOSITOL
-4-PHOSPHATE
5-KINASE, TYPE I,
ALPHA

(Danio rerio) 		PF01504
(PIP5K) 		4 ILE A 218
VAL A  92
GLU A  94
SER A  95
 None
 0.67A 6fbvC-5e3tA:
undetectable		 6fbvC-5e3tA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e8h GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE 3,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00348
(polyprenyl_synt) 		4 ILE A 157
THR A 134
VAL A 135
GLU A 131
 None
 1.17A 6fbvC-5e8hA:
undetectable		 6fbvC-5e8hA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evm FUSION GLYCOPROTEIN
F0

(Nipah
henipavirus) 		PF00523
(Fusion_gly) 		4 ILE A 323
THR A  43
VAL A  42
GLU A 295
 None
 1.02A 6fbvC-5evmA:
undetectable		 6fbvC-5evmA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f3q PUTATIVE
UNCHARACTERIZED
PROTEIN

(Entamoeba
histolytica) 		no annotation 4 ILE A 169
THR A  88
VAL A  89
SER A  82
 None
 0.86A 6fbvC-5f3qA:
undetectable		 6fbvC-5f3qA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE

(Oceanobacillus
iheyensis) 		PF01661
(Macro) 		4 ILE A  93
THR A  89
VAL A  73
GLU A  72
 None
 1.17A 6fbvC-5fudA:
undetectable		 6fbvC-5fudA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gy2 FLAGELLIN

(Bacillus
subtilis) 		PF00669
(Flagellin_N)
PF00700
(Flagellin_C) 		4 ILE C 122
THR C  94
VAL C  95
GLU C  92
 None
 0.84A 6fbvC-5gy2C:
undetectable		 6fbvC-5gy2C:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hh9 PVDN

(Pseudomonas
aeruginosa) 		PF00266
(Aminotran_5) 		4 ILE A 336
THR A 357
VAL A 356
SER A 205
 None
None
None
PLP  A 501 (-2.6A)
 1.01A 6fbvC-5hh9A:
undetectable		 6fbvC-5hh9A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikj CRYPTIC LOCI
REGULATOR 2

(Schizosaccharomyces
pombe) 		PF10383
(Clr2)
PF16761
(Clr2_transil) 		4 ILE A  66
GLN A  64
THR A 352
VAL A 353
 None
 1.17A 6fbvC-5ikjA:
undetectable		 6fbvC-5ikjA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k95 GTP CYCLOHYDROLASE
FOLE2

(Neisseria
gonorrhoeae) 		PF02649
(GCHY-1) 		4 ILE A 181
VAL A 236
GLU A 238
SER A 239
 None
 0.67A 6fbvC-5k95A:
undetectable		 6fbvC-5k95A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF12859
(ANAPC1) 		4 ILE A1464
THR A1507
VAL A1506
GLU A1455
 None
 0.95A 6fbvC-5lcwA:
undetectable		 6fbvC-5lcwA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nmi CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL

(Bos taurus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 THR A 372
VAL A 375
GLU A  28
SER A  27
 None
 1.17A 6fbvC-5nmiA:
undetectable		 6fbvC-5nmiA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osb PROTON-GATED ION
CHANNEL,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1

(Mus musculus;
Gloeobacter
violaceus) 		no annotation 4 MET A 235
ILE A 234
THR A 264
SER A 269
 None
 0.90A 6fbvC-5osbA:
undetectable		 6fbvC-5osbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5teb RECOGNITION OF
PERONOSPORA
PARASITICA 1

(Arabidopsis
thaliana) 		PF01582
(TIR) 		4 MET A 169
ILE A 168
VAL A 214
SER A 159
 None
 0.97A 6fbvC-5tebA:
1.4		 6fbvC-5tebA:
9.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tw1 DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Mycolicibacterium
smegmatis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF10385
(RNA_pol_Rpb2_45) 		4 ILE C1043
GLN C1045
THR C1087
LYS C1092
 None
 1.09A 6fbvC-5tw1C:
44.1		 6fbvC-5tw1C:
91.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tw1 DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Mycolicibacterium
smegmatis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF10385
(RNA_pol_Rpb2_45) 		4 ILE C1043
GLN C1045
THR C1087
VAL C1088
 None
 0.95A 6fbvC-5tw1C:
44.1		 6fbvC-5tw1C:
91.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8s CELL DIVISION
CONTROL PROTEIN 45

(Saccharomyces
cerevisiae) 		PF02724
(CDC45) 		4 ILE E 255
GLN E 254
THR E 147
VAL E 148
 None
 1.12A 6fbvC-5u8sE:
undetectable		 6fbvC-5u8sE:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc5 CHS2 CHALCONE
SYNTHASE

(Malus domestica) 		no annotation 4 ILE A 246
GLN A 244
THR A 169
VAL A 170
 None
 0.86A 6fbvC-5uc5A:
undetectable		 6fbvC-5uc5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uc7 ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(environmental
samples) 		PF00202
(Aminotran_3) 		4 ILE A 265
VAL A  96
GLU A 104
SER A 289
 None
None
TAR  A 501 (-3.9A)
None
 1.12A 6fbvC-5uc7A:
undetectable		 6fbvC-5uc7A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uin FORMYLTRANSFERASE

(Salmonella
enterica) 		PF00551
(Formyl_trans_N)
PF13637
(Ank_4) 		4 MET A 243
ILE A 242
VAL A 266
SER A 238
 None
 0.98A 6fbvC-5uinA:
undetectable		 6fbvC-5uinA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vog PUTATIVE
PHOSPHORIBOSYLTRANSF
ERASE

(Neisseria
gonorrhoeae) 		PF00156
(Pribosyltran) 		4 ILE A  34
THR A 105
VAL A 104
GLU A 107
 None
EDO  A 202 ( 3.4A)
G4P  A 203 (-4.6A)
None
 1.06A 6fbvC-5vogA:
undetectable		 6fbvC-5vogA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8q BIS3 BIPHENYL
SYNTHASE

(Malus domestica) 		no annotation 4 ILE A 241
GLN A 239
THR A 164
VAL A 165
 None
 0.86A 6fbvC-5w8qA:
0.3		 6fbvC-5w8qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu3 SPECKLE TARGETED
PIP5K1A-REGULATED
POLY(A) POLYMERASE

(Homo sapiens) 		PF03828
(PAP_assoc) 		4 ILE A 635
THR A 811
VAL A 810
GLU A 807
 None
 0.99A 6fbvC-5wu3A:
undetectable		 6fbvC-5wu3A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x32 N-ACYLGLUCOSAMINE
2-EPIMERASE

(Marinomonas
mediterranea) 		no annotation 4 ILE A 359
THR A 381
GLU A 316
SER A 317
 None
 1.15A 6fbvC-5x32A:
undetectable		 6fbvC-5x32A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtb NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
6, MITOCHONDRIAL

(Homo sapiens) 		PF10276
(zf-CHCC) 		4 GLN T 118
THR T 109
GLU T  79
SER T  78
 None
 1.06A 6fbvC-5xtbT:
undetectable		 6fbvC-5xtbT:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyb -

(-) 		no annotation 4 ILE A 177
THR A 146
GLU A 184
SER A 183
 None
 1.11A 6fbvC-5xybA:
undetectable		 6fbvC-5xybA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ztp CARBONIC ANHYDRASE

(Glaciozyma
antarctica) 		no annotation 4 GLN A  77
THR A 151
VAL A 152
GLU A  84
 None
 1.12A 6fbvC-5ztpA:
undetectable		 6fbvC-5ztpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3n NLEG5-1

(Escherichia
coli) 		no annotation 4 ILE A  77
THR A  95
VAL A  96
GLU A  93
 None
 0.89A 6fbvC-6b3nA:
undetectable		 6fbvC-6b3nA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6u GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1

(Homo sapiens) 		no annotation 4 MET B 236
ILE B 235
THR B 265
SER B 270
 None
 0.77A 6fbvC-6d6uB:
undetectable		 6fbvC-6d6uB:
15.87