SIMILAR PATTERNS OF AMINO ACIDS FOR 6F3M_B_ADNB502_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amu | GRAMICIDINSYNTHETASE 1 (Brevibacillusbrevis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | GLN A 356THR A 31THR A 334LEU A 210 | None | 1.40A | 6f3mB-1amuA:2.4 | 6f3mB-1amuA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l4i | SFAE PROTEIN (Escherichiacoli) |
PF00345(PapD_N)PF02753(PapD_C) | 4 | GLN A 170THR A 146THR A 151LEU A 114 | None | 1.37A | 6f3mB-1l4iA:undetectable | 6f3mB-1l4iA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lfp | HYPOTHETICAL PROTEINAQ_1575 (Aquifexaeolicus) |
PF01709(Transcrip_reg) | 4 | GLN A 55THR A 51THR A 175LEU A 187 | None | 1.46A | 6f3mB-1lfpA:undetectable | 6f3mB-1lfpA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ml4 | ASPARTATETRANSCARBAMOYLASE (Pyrococcusabyssi) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | GLN A 138THR A 137THR A 49LEU A 60 | PAL A 385 (-4.7A)NoneNoneNone | 1.47A | 6f3mB-1ml4A:9.7 | 6f3mB-1ml4A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pem | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2ALPHA CHAIN (Salmonellaenterica) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF08343(RNR_N) | 4 | GLN A 158THR A 161THR A 110LEU A 103 | None | 1.38A | 6f3mB-1pemA:undetectable | 6f3mB-1pemA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wd3 | ALPHA-L-ARABINOFURANOSIDASE B (Aspergilluskawachii) |
PF05270(AbfB)PF09206(ArabFuran-catal) | 4 | GLN A 103THR A 144THR A 37LEU A 52 | None | 1.24A | 6f3mB-1wd3A:undetectable | 6f3mB-1wd3A:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzo | HPCE (Thermusthermophilus) |
PF01557(FAA_hydrolase) | 4 | GLN A 167THR A 185THR A 124LEU A 212 | None | 1.34A | 6f3mB-1wzoA:undetectable | 6f3mB-1wzoA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zvs | MHC CLASS I ANTIGEN (Macaca mulatta) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 218THR A 216THR A 187LEU A 266 | None | 1.41A | 6f3mB-1zvsA:undetectable | 6f3mB-1zvsA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a81 | CARB (Pectobacteriumcarotovorum) |
PF00378(ECH_1) | 4 | GLN A 220THR A 221THR A 148LEU A 91 | None | 1.07A | 6f3mB-2a81A:undetectable | 6f3mB-2a81A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | GLN A1126THR A1398THR A1268LEU A1483 | None | 1.35A | 6f3mB-2b39A:undetectable | 6f3mB-2b39A:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cc0 | ACETYL-XYLANESTERASE (Streptomyceslividans) |
PF01522(Polysacc_deac_1) | 4 | GLN A 170THR A 171THR A 161LEU A 26 | None | 1.47A | 6f3mB-2cc0A:undetectable | 6f3mB-2cc0A:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6b | ADENOSINE KINASE (Homo sapiens) |
PF00294(PfkB) | 4 | GLN A 266THR A 271THR A 248LEU A 197 | None | 1.50A | 6f3mB-2i6bA:4.8 | 6f3mB-2i6bA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2puq | TISSUE FACTOR (Homo sapiens) |
PF01108(Tissue_fac)PF09294(Interfer-bind) | 4 | GLN T 190THR T 203THR T 106LEU T 143 | None | 1.24A | 6f3mB-2puqT:undetectable | 6f3mB-2puqT:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rk5 | PUTATIVE HEMOLYSIN (Streptococcusmutans) |
PF03471(CorC_HlyC) | 4 | GLN A 3THR A 19THR A 29LEU A 70 | None | 1.35A | 6f3mB-2rk5A:undetectable | 6f3mB-2rk5A:12.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xt0 | HALOALKANEDEHALOGENASE (Plesiocystispacifica) |
PF00561(Abhydrolase_1) | 4 | GLN A 236THR A 235THR A 241LEU A 130 | None | 1.34A | 6f3mB-2xt0A:6.5 | 6f3mB-2xt0A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3any | ETHANOLAMINEAMMONIA-LYASE HEAVYCHAIN (Escherichiacoli) |
PF06751(EutB) | 4 | GLN A 405THR A 366THR A 325LEU A 379 | None | 1.22A | 6f3mB-3anyA:undetectable | 6f3mB-3anyA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bgk | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcusmutans) |
PF01256(Carb_kinase) | 4 | GLN A 146THR A 144THR A 150LEU A 96 | None | 1.48A | 6f3mB-3bgkA:6.8 | 6f3mB-3bgkA:20.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 73THR A 74THR A 219LEU A 407 | ADN A 500 (-3.6A)ADN A 500 (-4.5A)NAD A 550 ( 2.8A)NAD A 550 (-4.2A) | 0.59A | 6f3mB-3ce6A:52.2 | 6f3mB-3ce6A:48.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0m | PEPTIDE METHIONINESULFOXIDE REDUCTASEMSRA/MSRB 1 (Streptococcuspneumoniae) |
PF01625(PMSR)PF01641(SelR) | 4 | GLN A 35THR A 47THR A 52LEU A 128 | None | 1.30A | 6f3mB-3e0mA:undetectable | 6f3mB-3e0mA:21.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 56THR A 57THR A 156LEU A 343 | ADN A 438 (-3.8A)ADN A 438 (-4.6A)NAD A 439 ( 3.0A)NAD A 439 ( 4.0A) | 0.56A | 6f3mB-3g1uA:54.7 | 6f3mB-3g1uA:55.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 66THR A 67THR A 200LEU A 385 | RAB A 602 (-3.9A)RAB A 602 (-4.5A)NAD A 601 ( 2.9A)NAD A 601 ( 4.1A) | 0.48A | 6f3mB-3glqA:53.9 | 6f3mB-3glqA:50.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 56THR A 57THR A 156LEU A 343 | ADN A 439 (-3.6A)ADN A 439 (-4.7A)NAD A 438 (-3.8A)NAD A 438 (-4.0A) | 0.40A | 6f3mB-3h9uA:56.8 | 6f3mB-3h9uA:56.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ip1 | ALCOHOLDEHYDROGENASE,ZINC-CONTAINING (Thermotogamaritima) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLN A 74THR A 75THR A 87LEU A 93 | None | 1.38A | 6f3mB-3ip1A:4.9 | 6f3mB-3ip1A:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jts | MHC CLASS IMAMU-A*02 (Macaca mulatta) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 218THR A 216THR A 187LEU A 266 | None | 1.33A | 6f3mB-3jtsA:undetectable | 6f3mB-3jtsA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kyo | MHC CLASS I ANTIGEN (Homo sapiens) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 218THR A 216THR A 187LEU A 266 | None | 1.46A | 6f3mB-3kyoA:undetectable | 6f3mB-3kyoA:20.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 59THR A 60THR A 193LEU A 378 | K A 2 ( 3.3A)ADN A 500 (-4.6A)NAD A 550 ( 3.0A)NAD A 550 (-4.3A) | 0.47A | 6f3mB-3n58A:54.2 | 6f3mB-3n58A:53.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 66THR A 67THR A 206LEU A 395 | ADE A 506 (-3.8A)ADE A 506 (-4.5A)NAD A 501 (-2.8A)NAD A 501 (-4.2A) | 0.29A | 6f3mB-3oneA:51.5 | 6f3mB-3oneA:47.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pl1 | PYRAZINAMIDASE/NICOTINAMIDASE PNCA(PZASE) (Mycobacteriumtuberculosis) |
PF00857(Isochorismatase) | 4 | GLN A 141THR A 142THR A 160LEU A 172 | None | 1.38A | 6f3mB-3pl1A:3.2 | 6f3mB-3pl1A:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | GLN C 209THR C 172THR C 491LEU C 506 | None | 1.46A | 6f3mB-3qgkC:undetectable | 6f3mB-3qgkC:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rha | PUTRESCINE OXIDASE (Paenarthrobacteraurescens) |
PF01593(Amino_oxidase) | 4 | GLN A 217THR A 46THR A 21LEU A 77 | NoneFDA A 483 ( 4.2A)NoneNone | 1.20A | 6f3mB-3rhaA:2.4 | 6f3mB-3rhaA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rw9 | SPERMIDINE SYNTHASE (Homo sapiens) |
PF01564(Spermine_synth)PF17284(Spermine_synt_N) | 4 | GLN A 245THR A 237THR A 72LEU A 33 | None | 1.44A | 6f3mB-3rw9A:5.1 | 6f3mB-3rw9A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2s | PUTATIVEPYRAZINAMIDASE/NICOTINAMIDASE (Streptococcusmutans) |
PF00857(Isochorismatase) | 4 | GLN A 150THR A 125THR A 140LEU A 173 | None | 1.39A | 6f3mB-3s2sA:3.5 | 6f3mB-3s2sA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x27 | CUCUMOPINE SYNTHASE (Marinactinosporathermotolerans) |
no annotation | 4 | GLN A 168THR A 171THR A 263LEU A 219 | None | 1.27A | 6f3mB-3x27A:undetectable | 6f3mB-3x27A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a73 | L-LACTATEDEHYDROGENASE (Thermusthermophilus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLN A 147THR A 146THR A 165LEU A 289 | None | 1.44A | 6f3mB-4a73A:5.3 | 6f3mB-4a73A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hsu | LYSINE-SPECIFICHISTONE DEMETHYLASE1B (Homo sapiens) |
PF01593(Amino_oxidase)PF04433(SWIRM)PF07496(zf-CW) | 4 | GLN A 141THR A 143THR A 160LEU A 153 | None | 1.42A | 6f3mB-4hsuA:2.9 | 6f3mB-4hsuA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lcy | HLA CLASS IHISTOCOMPATIBILITYANTIGEN, B-46 ALPHACHAIN (Homo sapiens) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 218THR A 216THR A 187LEU A 266 | NoneNone NA A 301 (-2.9A)None | 1.37A | 6f3mB-4lcyA:undetectable | 6f3mB-4lcyA:21.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lvc | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE(SAHASE) (Bradyrhizobiumelkanii) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 62THR A 63THR A 198LEU A 383 | NH4 A 502 ( 3.1A)ADN A 501 (-4.5A)NAD A 503 ( 2.9A)NAD A 503 ( 3.9A) | 0.17A | 6f3mB-4lvcA:53.5 | 6f3mB-4lvcA:53.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | GLN A 159THR A 229THR A 235LEU A 168 | None | 1.43A | 6f3mB-4n6kA:undetectable | 6f3mB-4n6kA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvm | CITRATE SYNTHASE (Mycobacteriumtuberculosis) |
PF00285(Citrate_synt) | 4 | GLN A 111THR A 195THR A 204LEU A 389 | None | 1.19A | 6f3mB-4tvmA:undetectable | 6f3mB-4tvmA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u0g | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT 2 (Mycobacteriumtuberculosis) |
PF00574(CLP_protease) | 4 | GLN A 136THR A 183THR A 167LEU A 86 | NoneNoneNoneZIL A 301 ( 4.3A) | 1.47A | 6f3mB-4u0gA:undetectable | 6f3mB-4u0gA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xjx | HSDR (Escherichiacoli) |
PF04313(HSDR_N)PF04851(ResIII)PF12008(EcoR124_C) | 4 | GLN A 249THR A 252THR A 209LEU A 40 | None | 1.49A | 6f3mB-4xjxA:2.6 | 6f3mB-4xjxA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y4r | BIFUNCTIONALLYSINE-SPECIFICDEMETHYLASE ANDHISTIDYL-HYDROXYLASENO66 (Homo sapiens) |
PF08007(Cupin_4) | 4 | GLN A 540THR A 515THR A 307LEU A 205 | None | 1.49A | 6f3mB-4y4rA:undetectable | 6f3mB-4y4rA:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1n | MHC CLASS I ANTIGEN (Canis lupus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 219THR A 217THR A 188LEU A 267 | None | 1.40A | 6f3mB-5f1nA:undetectable | 6f3mB-5f1nA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g23 | TYPE-IV LIKE PILINTTHA1219 (Thermusthermophilus) |
no annotation | 4 | GLN A 84THR A 107THR A 231LEU A 178 | None | 1.45A | 6f3mB-5g23A:undetectable | 6f3mB-5g23A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gza | PROTEIN O-MANNOSEKINASE (Danio rerio) |
PF07714(Pkinase_Tyr) | 4 | GLN A 212THR A 209THR A 277LEU A 246 | MG A 403 (-2.6A)NoneNoneNone | 1.39A | 6f3mB-5gzaA:undetectable | 6f3mB-5gzaA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u47 | PENICILLIN BINDINGPROTEIN 2X (Streptococcusthermophilus) |
PF00905(Transpeptidase)PF03717(PBP_dimer)PF03793(PASTA) | 4 | GLN A 484THR A 303THR A 297LEU A 270 | None | 1.34A | 6f3mB-5u47A:undetectable | 6f3mB-5u47A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w5f | TAIL TUBE PROTEINGP19 (Enterobacteriaphage T4 sensulato) |
PF06841(Phage_T4_gp19) | 4 | GLN A 35THR A 33THR A 39LEU A 157 | None | 1.39A | 6f3mB-5w5fA:undetectable | 6f3mB-5w5fA:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 4 | GLN A1189THR A1185THR A1093LEU A1116 | None | 1.45A | 6f3mB-5welA:4.2 | 6f3mB-5welA:19.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | GLN A 62THR A 63THR A 162LEU A 349 | ADN A 501 (-3.8A)ADN A 501 (-4.5A)NAD A 500 ( 2.9A)NAD A 500 ( 4.3A) | 0.59A | 6f3mB-6aphA:58.1 | 6f3mB-6aphA:56.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 4 | GLN A 60THR A 61THR A 160LEU A 347 | NA A 503 ( 3.2A)ADN A 501 (-4.6A)NAD A 502 ( 2.8A)NAD A 502 (-3.9A) | 0.18A | 6f3mB-6gbnA:57.5 | 6f3mB-6gbnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gmb | HYDROXYACID OXIDASE1 (Homo sapiens) |
no annotation | 4 | GLN A 350THR A 60THR A 64LEU A 304 | None | 1.05A | 6f3mB-6gmbA:undetectable | 6f3mB-6gmbA:11.34 |