SIMILAR PATTERNS OF AMINO ACIDS FOR 6F3M_B_ADNB502_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1amu GRAMICIDIN
SYNTHETASE 1


(Brevibacillus
brevis)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
4 GLN A 356
THR A  31
THR A 334
LEU A 210
None
1.40A 6f3mB-1amuA:
2.4
6f3mB-1amuA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l4i SFAE PROTEIN

(Escherichia
coli)
PF00345
(PapD_N)
PF02753
(PapD_C)
4 GLN A 170
THR A 146
THR A 151
LEU A 114
None
1.37A 6f3mB-1l4iA:
undetectable
6f3mB-1l4iA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfp HYPOTHETICAL PROTEIN
AQ_1575


(Aquifex
aeolicus)
PF01709
(Transcrip_reg)
4 GLN A  55
THR A  51
THR A 175
LEU A 187
None
1.46A 6f3mB-1lfpA:
undetectable
6f3mB-1lfpA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ml4 ASPARTATE
TRANSCARBAMOYLASE


(Pyrococcus
abyssi)
PF00185
(OTCace)
PF02729
(OTCace_N)
4 GLN A 138
THR A 137
THR A  49
LEU A  60
PAL  A 385 (-4.7A)
None
None
None
1.47A 6f3mB-1ml4A:
9.7
6f3mB-1ml4A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pem RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 2
ALPHA CHAIN


(Salmonella
enterica)
PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF08343
(RNR_N)
4 GLN A 158
THR A 161
THR A 110
LEU A 103
None
1.38A 6f3mB-1pemA:
undetectable
6f3mB-1pemA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wd3 ALPHA-L-ARABINOFURAN
OSIDASE B


(Aspergillus
kawachii)
PF05270
(AbfB)
PF09206
(ArabFuran-catal)
4 GLN A 103
THR A 144
THR A  37
LEU A  52
None
1.24A 6f3mB-1wd3A:
undetectable
6f3mB-1wd3A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzo HPCE

(Thermus
thermophilus)
PF01557
(FAA_hydrolase)
4 GLN A 167
THR A 185
THR A 124
LEU A 212
None
1.34A 6f3mB-1wzoA:
undetectable
6f3mB-1wzoA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvs MHC CLASS I ANTIGEN

(Macaca mulatta)
PF00129
(MHC_I)
PF07654
(C1-set)
4 GLN A 218
THR A 216
THR A 187
LEU A 266
None
1.41A 6f3mB-1zvsA:
undetectable
6f3mB-1zvsA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a81 CARB

(Pectobacterium
carotovorum)
PF00378
(ECH_1)
4 GLN A 220
THR A 221
THR A 148
LEU A  91
None
1.07A 6f3mB-2a81A:
undetectable
6f3mB-2a81A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus)
PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
4 GLN A1126
THR A1398
THR A1268
LEU A1483
None
1.35A 6f3mB-2b39A:
undetectable
6f3mB-2b39A:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cc0 ACETYL-XYLAN
ESTERASE


(Streptomyces
lividans)
PF01522
(Polysacc_deac_1)
4 GLN A 170
THR A 171
THR A 161
LEU A  26
None
1.47A 6f3mB-2cc0A:
undetectable
6f3mB-2cc0A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6b ADENOSINE KINASE

(Homo sapiens)
PF00294
(PfkB)
4 GLN A 266
THR A 271
THR A 248
LEU A 197
None
1.50A 6f3mB-2i6bA:
4.8
6f3mB-2i6bA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2puq TISSUE FACTOR

(Homo sapiens)
PF01108
(Tissue_fac)
PF09294
(Interfer-bind)
4 GLN T 190
THR T 203
THR T 106
LEU T 143
None
1.24A 6f3mB-2puqT:
undetectable
6f3mB-2puqT:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rk5 PUTATIVE HEMOLYSIN

(Streptococcus
mutans)
PF03471
(CorC_HlyC)
4 GLN A   3
THR A  19
THR A  29
LEU A  70
None
1.35A 6f3mB-2rk5A:
undetectable
6f3mB-2rk5A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt0 HALOALKANE
DEHALOGENASE


(Plesiocystis
pacifica)
PF00561
(Abhydrolase_1)
4 GLN A 236
THR A 235
THR A 241
LEU A 130
None
1.34A 6f3mB-2xt0A:
6.5
6f3mB-2xt0A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3any ETHANOLAMINE
AMMONIA-LYASE HEAVY
CHAIN


(Escherichia
coli)
PF06751
(EutB)
4 GLN A 405
THR A 366
THR A 325
LEU A 379
None
1.22A 6f3mB-3anyA:
undetectable
6f3mB-3anyA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN


(Streptococcus
mutans)
PF01256
(Carb_kinase)
4 GLN A 146
THR A 144
THR A 150
LEU A  96
None
1.48A 6f3mB-3bgkA:
6.8
6f3mB-3bgkA:
20.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ce6 ADENOSYLHOMOCYSTEINA
SE


(Mycobacterium
tuberculosis)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  73
THR A  74
THR A 219
LEU A 407
ADN  A 500 (-3.6A)
ADN  A 500 (-4.5A)
NAD  A 550 ( 2.8A)
NAD  A 550 (-4.2A)
0.59A 6f3mB-3ce6A:
52.2
6f3mB-3ce6A:
48.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0m PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB 1


(Streptococcus
pneumoniae)
PF01625
(PMSR)
PF01641
(SelR)
4 GLN A  35
THR A  47
THR A  52
LEU A 128
None
1.30A 6f3mB-3e0mA:
undetectable
6f3mB-3e0mA:
21.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g1u ADENOSYLHOMOCYSTEINA
SE


(Leishmania
major)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  56
THR A  57
THR A 156
LEU A 343
ADN  A 438 (-3.8A)
ADN  A 438 (-4.6A)
NAD  A 439 ( 3.0A)
NAD  A 439 ( 4.0A)
0.56A 6f3mB-3g1uA:
54.7
6f3mB-3g1uA:
55.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3glq ADENOSYLHOMOCYSTEINA
SE


(Burkholderia
pseudomallei)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  66
THR A  67
THR A 200
LEU A 385
RAB  A 602 (-3.9A)
RAB  A 602 (-4.5A)
NAD  A 601 ( 2.9A)
NAD  A 601 ( 4.1A)
0.48A 6f3mB-3glqA:
53.9
6f3mB-3glqA:
50.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h9u ADENOSYLHOMOCYSTEINA
SE


(Trypanosoma
brucei)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  56
THR A  57
THR A 156
LEU A 343
ADN  A 439 (-3.6A)
ADN  A 439 (-4.7A)
NAD  A 438 (-3.8A)
NAD  A 438 (-4.0A)
0.40A 6f3mB-3h9uA:
56.8
6f3mB-3h9uA:
56.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ip1 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING


(Thermotoga
maritima)
PF00107
(ADH_zinc_N)
PF08240
(ADH_N)
4 GLN A  74
THR A  75
THR A  87
LEU A  93
None
1.38A 6f3mB-3ip1A:
4.9
6f3mB-3ip1A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jts MHC CLASS I
MAMU-A*02


(Macaca mulatta)
PF00129
(MHC_I)
PF07654
(C1-set)
4 GLN A 218
THR A 216
THR A 187
LEU A 266
None
1.33A 6f3mB-3jtsA:
undetectable
6f3mB-3jtsA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyo MHC CLASS I ANTIGEN

(Homo sapiens)
PF00129
(MHC_I)
PF07654
(C1-set)
4 GLN A 218
THR A 216
THR A 187
LEU A 266
None
1.46A 6f3mB-3kyoA:
undetectable
6f3mB-3kyoA:
20.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3n58 ADENOSYLHOMOCYSTEINA
SE


(Brucella
abortus)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  59
THR A  60
THR A 193
LEU A 378
K  A   2 ( 3.3A)
ADN  A 500 (-4.6A)
NAD  A 550 ( 3.0A)
NAD  A 550 (-4.3A)
0.47A 6f3mB-3n58A:
54.2
6f3mB-3n58A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3one ADENOSYLHOMOCYSTEINA
SE


(Lupinus luteus)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  66
THR A  67
THR A 206
LEU A 395
ADE  A 506 (-3.8A)
ADE  A 506 (-4.5A)
NAD  A 501 (-2.8A)
NAD  A 501 (-4.2A)
0.29A 6f3mB-3oneA:
51.5
6f3mB-3oneA:
47.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pl1 PYRAZINAMIDASE/NICOT
INAMIDASE PNCA
(PZASE)


(Mycobacterium
tuberculosis)
PF00857
(Isochorismatase)
4 GLN A 141
THR A 142
THR A 160
LEU A 172
None
1.38A 6f3mB-3pl1A:
3.2
6f3mB-3pl1A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgk UREASE SUBUNIT BETA
2


(Helicobacter
mustelae)
PF00449
(Urease_alpha)
PF01979
(Amidohydro_1)
4 GLN C 209
THR C 172
THR C 491
LEU C 506
None
1.46A 6f3mB-3qgkC:
undetectable
6f3mB-3qgkC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rha PUTRESCINE OXIDASE

(Paenarthrobacter
aurescens)
PF01593
(Amino_oxidase)
4 GLN A 217
THR A  46
THR A  21
LEU A  77
None
FDA  A 483 ( 4.2A)
None
None
1.20A 6f3mB-3rhaA:
2.4
6f3mB-3rhaA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rw9 SPERMIDINE SYNTHASE

(Homo sapiens)
PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N)
4 GLN A 245
THR A 237
THR A  72
LEU A  33
None
1.44A 6f3mB-3rw9A:
5.1
6f3mB-3rw9A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s2s PUTATIVE
PYRAZINAMIDASE/NICOT
INAMIDASE


(Streptococcus
mutans)
PF00857
(Isochorismatase)
4 GLN A 150
THR A 125
THR A 140
LEU A 173
None
1.39A 6f3mB-3s2sA:
3.5
6f3mB-3s2sA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x27 CUCUMOPINE SYNTHASE

(Marinactinospora
thermotolerans)
no annotation 4 GLN A 168
THR A 171
THR A 263
LEU A 219
None
1.27A 6f3mB-3x27A:
undetectable
6f3mB-3x27A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a73 L-LACTATE
DEHYDROGENASE


(Thermus
thermophilus)
PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C)
4 GLN A 147
THR A 146
THR A 165
LEU A 289
None
1.44A 6f3mB-4a73A:
5.3
6f3mB-4a73A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B


(Homo sapiens)
PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW)
4 GLN A 141
THR A 143
THR A 160
LEU A 153
None
1.42A 6f3mB-4hsuA:
2.9
6f3mB-4hsuA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcy HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-46 ALPHA
CHAIN


(Homo sapiens)
PF00129
(MHC_I)
PF07654
(C1-set)
4 GLN A 218
THR A 216
THR A 187
LEU A 266
None
None
NA  A 301 (-2.9A)
None
1.37A 6f3mB-4lcyA:
undetectable
6f3mB-4lcyA:
21.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lvc S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE)


(Bradyrhizobium
elkanii)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  62
THR A  63
THR A 198
LEU A 383
NH4  A 502 ( 3.1A)
ADN  A 501 (-4.5A)
NAD  A 503 ( 2.9A)
NAD  A 503 ( 3.9A)
0.17A 6f3mB-4lvcA:
53.5
6f3mB-4lvcA:
53.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6k TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT


(Desulfovibrio
salexigens)
PF03480
(DctP)
4 GLN A 159
THR A 229
THR A 235
LEU A 168
None
1.43A 6f3mB-4n6kA:
undetectable
6f3mB-4n6kA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvm CITRATE SYNTHASE

(Mycobacterium
tuberculosis)
PF00285
(Citrate_synt)
4 GLN A 111
THR A 195
THR A 204
LEU A 389
None
1.19A 6f3mB-4tvmA:
undetectable
6f3mB-4tvmA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0g ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2


(Mycobacterium
tuberculosis)
PF00574
(CLP_protease)
4 GLN A 136
THR A 183
THR A 167
LEU A  86
None
None
None
ZIL  A 301 ( 4.3A)
1.47A 6f3mB-4u0gA:
undetectable
6f3mB-4u0gA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xjx HSDR

(Escherichia
coli)
PF04313
(HSDR_N)
PF04851
(ResIII)
PF12008
(EcoR124_C)
4 GLN A 249
THR A 252
THR A 209
LEU A  40
None
1.49A 6f3mB-4xjxA:
2.6
6f3mB-4xjxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4r BIFUNCTIONAL
LYSINE-SPECIFIC
DEMETHYLASE AND
HISTIDYL-HYDROXYLASE
NO66


(Homo sapiens)
PF08007
(Cupin_4)
4 GLN A 540
THR A 515
THR A 307
LEU A 205
None
1.49A 6f3mB-4y4rA:
undetectable
6f3mB-4y4rA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1n MHC CLASS I ANTIGEN

(Canis lupus)
PF00129
(MHC_I)
PF07654
(C1-set)
4 GLN A 219
THR A 217
THR A 188
LEU A 267
None
1.40A 6f3mB-5f1nA:
undetectable
6f3mB-5f1nA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g23 TYPE-IV LIKE PILIN
TTHA1219


(Thermus
thermophilus)
no annotation 4 GLN A  84
THR A 107
THR A 231
LEU A 178
None
1.45A 6f3mB-5g23A:
undetectable
6f3mB-5g23A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gza PROTEIN O-MANNOSE
KINASE


(Danio rerio)
PF07714
(Pkinase_Tyr)
4 GLN A 212
THR A 209
THR A 277
LEU A 246
MG  A 403 (-2.6A)
None
None
None
1.39A 6f3mB-5gzaA:
undetectable
6f3mB-5gzaA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u47 PENICILLIN BINDING
PROTEIN 2X


(Streptococcus
thermophilus)
PF00905
(Transpeptidase)
PF03717
(PBP_dimer)
PF03793
(PASTA)
4 GLN A 484
THR A 303
THR A 297
LEU A 270
None
1.34A 6f3mB-5u47A:
undetectable
6f3mB-5u47A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5f TAIL TUBE PROTEIN
GP19


(Enterobacteria
phage T4 sensu
lato)
PF06841
(Phage_T4_gp19)
4 GLN A  35
THR A  33
THR A  39
LEU A 157
None
1.39A 6f3mB-5w5fA:
undetectable
6f3mB-5w5fA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN


(Mus musculus;
Rattus
norvegicus)
PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF07803
(GSG-1)
PF10613
(Lig_chan-Glu_bd)
4 GLN A1189
THR A1185
THR A1093
LEU A1116
None
1.45A 6f3mB-5welA:
4.2
6f3mB-5welA:
19.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6aph ADENOSYLHOMOCYSTEINA
SE


(Elizabethkingia
anophelis)
PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase)
4 GLN A  62
THR A  63
THR A 162
LEU A 349
ADN  A 501 (-3.8A)
ADN  A 501 (-4.5A)
NAD  A 500 ( 2.9A)
NAD  A 500 ( 4.3A)
0.59A 6f3mB-6aphA:
58.1
6f3mB-6aphA:
56.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-)
no annotation 4 GLN A  60
THR A  61
THR A 160
LEU A 347
NA  A 503 ( 3.2A)
ADN  A 501 (-4.6A)
NAD  A 502 ( 2.8A)
NAD  A 502 (-3.9A)
0.18A 6f3mB-6gbnA:
57.5
6f3mB-6gbnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gmb HYDROXYACID OXIDASE
1


(Homo sapiens)
no annotation 4 GLN A 350
THR A  60
THR A  64
LEU A 304
None
1.05A 6f3mB-6gmbA:
undetectable
6f3mB-6gmbA:
11.34