SIMILAR PATTERNS OF AMINO ACIDS FOR 6F32_B_ACTB602

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1air PECTATE LYASE C

(Dickeya
chrysanthemi) 		PF00544
(Pec_lyase_C) 		4 ASN A 232
TYR A 230
VAL A 227
THR A 206
 None
 1.36A 6f32B-1airA:
undetectable		 6f32B-1airA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bl5 ISOCITRATE
DEHYDROGENASE

(Escherichia
coli) 		PF00180
(Iso_dh) 		4 TYR A 296
VAL A 276
VAL A 225
THR A 226
 None
 1.34A 6f32B-1bl5A:
undetectable		 6f32B-1bl5A:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cz3 DIHYDROFOLATE
REDUCTASE

(Thermotoga
maritima) 		PF00186
(DHFR_1) 		4 ASN A  40
TYR A  94
VAL A  42
VAL A  86
 None
 1.46A 6f32B-1cz3A:
undetectable		 6f32B-1cz3A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ev1 ECHOVIRUS 1
ECHOVIRUS 1

(Enterovirus B;
Enterovirus B) 		PF00073
(Rhv)
PF00073
(Rhv) 		4 ASN 3 219
VAL 1  43
VAL 1  18
THR 1  17
 None
 1.06A 6f32B-1ev13:
undetectable		 6f32B-1ev13:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fw8 PHOSPHOGLYCERATE
KINASE

(Saccharomyces
cerevisiae) 		PF00162
(PGK) 		4 TYR A 122
VAL A 261
VAL A 295
THR A 294
 None
 1.43A 6f32B-1fw8A:
undetectable		 6f32B-1fw8A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gfn MATRIX PORIN OUTER
MEMBRANE PROTEIN F

(Escherichia
coli) 		PF00267
(Porin_1) 		4 ASN A 101
TYR A 102
VAL A 136
VAL A 104
 None
 1.38A 6f32B-1gfnA:
undetectable		 6f32B-1gfnA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1he3 BILIVERDIN IX BETA
REDUCTASE

(Homo sapiens) 		PF13460
(NAD_binding_10) 		4 TYR A 194
VAL A 107
VAL A 149
THR A 199
 None
 1.46A 6f32B-1he3A:
5.5		 6f32B-1he3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hvy THYMIDYLATE SYNTHASE

(Homo sapiens) 		PF00303
(Thymidylat_synt) 		4 ASN A 260
TYR A 258
VAL A 313
THR A  51
 None
UMP  A 314 ( 4.4A)
None
None
 1.20A 6f32B-1hvyA:
undetectable		 6f32B-1hvyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyh L-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Weissella
confusa) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ASN A 275
TYR A 286
VAL A 295
THR A 299
 None
 1.42A 6f32B-1hyhA:
3.7		 6f32B-1hyhA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hyh L-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Weissella
confusa) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 TYR A 193
VAL A 204
VAL A 209
THR A 208
 None
 1.25A 6f32B-1hyhA:
3.7		 6f32B-1hyhA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hze RIBOFLAVIN SYNTHASE
ALPHA CHAIN

(Escherichia
coli) 		PF00677
(Lum_binding) 		4 ASN A  55
VAL A  25
VAL A  51
THR A  52
 None
 1.29A 6f32B-1hzeA:
undetectable		 6f32B-1hzeA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1imv PIGMENT
EPITHELIUM-DERIVED
FACTOR

(Homo sapiens) 		PF00079
(Serpin) 		4 TYR A 212
VAL A 221
VAL A 219
THR A 218
 None
 1.43A 6f32B-1imvA:
undetectable		 6f32B-1imvA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus B;
Enterovirus B) 		PF00073
(Rhv)
PF00073
(Rhv) 		4 ASN C 218
VAL A  43
VAL A  18
THR A  17
 None
 1.04A 6f32B-1mqtC:
undetectable		 6f32B-1mqtC:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 ASN A 306
TYR A 302
VAL A 293
THR A 300
 None
 1.36A 6f32B-1qhoA:
undetectable		 6f32B-1qhoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpg 3-PHOSPHOGLYCERATE
KINASE

(Saccharomyces
cerevisiae) 		PF00162
(PGK) 		4 TYR A 193
VAL A 332
VAL A 366
THR A 365
 None
 1.39A 6f32B-1qpgA:
undetectable		 6f32B-1qpgA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu2 ISOLEUCYL-TRNA
SYNTHETASE

(Staphylococcus
aureus) 		PF00133
(tRNA-synt_1)
PF06827
(zf-FPG_IleRS)
PF08264
(Anticodon_1) 		4 ASN A 311
VAL A 309
VAL A 241
THR A 326
 None
 1.16A 6f32B-1qu2A:
undetectable		 6f32B-1qu2A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rkr AZURIN-I

(Achromobacter
xylosoxidans) 		PF00127
(Copper-bind) 		4 ASN A  47
TYR A  72
VAL A  49
VAL A  60
 None
 1.24A 6f32B-1rkrA:
undetectable		 6f32B-1rkrA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb8 WBPP

(Pseudomonas
aeruginosa) 		PF01370
(Epimerase) 		4 ASN A 241
TYR A 323
VAL A 265
VAL A 325
 None
 1.14A 6f32B-1sb8A:
4.0		 6f32B-1sb8A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5c CENTROMERIC PROTEIN
E

(Homo sapiens) 		PF00225
(Kinesin) 		4 TYR A  94
VAL A 105
VAL A  62
THR A  59
 ADP  A 600 (-3.5A)
None
None
None
 1.16A 6f32B-1t5cA:
undetectable		 6f32B-1t5cA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbl PECTATE LYASE 47

(Bacillus sp.
TS-47) 		PF00544
(Pec_lyase_C) 		4 ASN A 299
TYR A 297
VAL A 294
THR A 273
 None
 1.39A 6f32B-1vblA:
undetectable		 6f32B-1vblA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vm7 RIBOKINASE

(Thermotoga
maritima) 		PF00294
(PfkB) 		4 TYR A  76
VAL A   7
VAL A  60
THR A  61
 None
 1.32A 6f32B-1vm7A:
3.4		 6f32B-1vm7A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wom SIGMA FACTOR SIGB
REGULATION PROTEIN
RSBQ

(Bacillus
subtilis) 		PF12697
(Abhydrolase_6) 		4 ASN A 127
TYR A 133
VAL A 226
THR A 225
 None
 1.37A 6f32B-1womA:
undetectable		 6f32B-1womA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wou THIOREDOXIN -RELATED
PROTEIN, 14 KDA

(Homo sapiens) 		PF06110
(DUF953) 		4 VAL A 106
LYS A 104
VAL A  90
THR A  91
 None
 1.44A 6f32B-1wouA:
undetectable		 6f32B-1wouA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhn CELLULAR REPRESSOR
OF E1A-STIMULATED
GENES

(Homo sapiens) 		PF13883
(Pyrid_oxidase_2) 		4 ASN A  84
TYR A  86
VAL A 120
THR A 119
 None
 1.09A 6f32B-1xhnA:
undetectable		 6f32B-1xhnA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y71 KINASE-ASSOCIATED
PROTEIN B

(Bacillus cereus) 		PF08810
(KapB) 		4 TYR A  15
VAL A  36
VAL A  34
THR A  71
 None
 1.20A 6f32B-1y71A:
undetectable		 6f32B-1y71A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yis ADENYLOSUCCINATE
LYASE

(Caenorhabditis
elegans) 		PF00206
(Lyase_1) 		4 ASN A 145
VAL A 148
VAL A 365
THR A 362
 None
 1.27A 6f32B-1yisA:
undetectable		 6f32B-1yisA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2epk N-ACETYL-BETA-D-GLUC
OSAMINIDASE

(Streptococcus
gordonii) 		PF00728
(Glyco_hydro_20) 		4 TYR X 309
VAL X 369
VAL X 371
THR X 372
 None
 1.30A 6f32B-2epkX:
undetectable		 6f32B-2epkX:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f86 HYPOTHETICAL PROTEIN
K11E8.1D

(Caenorhabditis
elegans) 		PF08332
(CaMKII_AD) 		4 TYR B 431
VAL B 419
VAL B 354
THR B 357
 None
 1.29A 6f32B-2f86B:
undetectable		 6f32B-2f86B:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ft7 AZURIN

(Pseudomonas
aeruginosa) 		PF00127
(Copper-bind) 		4 ASN A  47
TYR A  72
VAL A  49
VAL A  60
 None
 1.42A 6f32B-2ft7A:
undetectable		 6f32B-2ft7A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5p GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
1

(Kluyveromyces
marxianus) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 ASN O 313
TYR O 311
VAL O 175
THR O 174
 None
 1.33A 6f32B-2i5pO:
2.5		 6f32B-2i5pO:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv0 ISOCITRATE
DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF00180
(Iso_dh) 		4 TYR A 290
VAL A 270
VAL A 218
THR A 219
 None
 1.39A 6f32B-2iv0A:
undetectable		 6f32B-2iv0A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4g HYALURONOGLUCOSAMINI
DASE

(Bacteroides
thetaiotaomicron) 		PF02838
(Glyco_hydro_20b)
PF07555
(NAGidase) 		4 ASN A 431
TYR A 435
VAL A 346
VAL A 342
 None
None
None
NB1  A1590 ( 4.9A)
 1.22A 6f32B-2j4gA:
undetectable		 6f32B-2j4gA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n67 HEMOLYSIN II

(Bacillus cereus) 		no annotation 4 ASN B  42
TYR B  45
VAL B  72
THR B  71
 None
 1.17A 6f32B-2n67B:
undetectable		 6f32B-2n67B:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o04 PECTATE LYASE

(Bacillus
subtilis) 		PF00544
(Pec_lyase_C) 		4 ASN A 293
TYR A 291
VAL A 288
THR A 267
 None
 1.41A 6f32B-2o04A:
undetectable		 6f32B-2o04A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rcb GLUTAMATE [NMDA]
RECEPTOR SUBUNIT 3B

(Rattus
norvegicus) 		PF10613
(Lig_chan-Glu_bd) 		4 TYR A  95
VAL A  10
VAL A 119
THR A 120
 DSN  A 901 (-3.3A)
None
None
None
 1.31A 6f32B-2rcbA:
undetectable		 6f32B-2rcbA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2re3 UNCHARACTERIZED
PROTEIN

(Ruegeria
pomeroyi) 		PF06938
(DUF1285) 		4 ASN A  37
VAL A  86
VAL A  80
THR A  81
 None
None
None
GOL  A 194 ( 4.5A)
 1.21A 6f32B-2re3A:
undetectable		 6f32B-2re3A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v95 CORTICOSTEROID-BINDI
NG GLOBULIN

(Rattus
norvegicus) 		PF00079
(Serpin) 		4 TYR A 192
VAL A 201
VAL A 199
THR A 198
 None
 1.31A 6f32B-2v95A:
undetectable		 6f32B-2v95A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoy RBAM17540

(Bacillus
amyloliquefaciens) 		PF03067
(LPMO_10) 		4 ASN A 198
TYR A  30
VAL A  67
VAL A  60
 None
 1.09A 6f32B-2yoyA:
undetectable		 6f32B-2yoyA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c3n DIHYDROOROTATE
DEHYDROGENASE

(Trypanosoma
cruzi) 		PF01180
(DHO_dh) 		4 ASN A 234
TYR A 170
VAL A 195
VAL A 198
 ASN  A 234 ( 0.6A)
TYR  A 170 (-1.3A)
VAL  A 195 (-0.6A)
VAL  A 198 ( 0.6A)
 1.27A 6f32B-3c3nA:
undetectable		 6f32B-3c3nA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cp7 ALKALINE SERINE
PROTEASE AL20

(Nesterenkonia
aethiopica) 		PF13365
(Trypsin_2) 		4 TYR A 211
VAL A  77
VAL A  96
THR A  35
 None
 1.17A 6f32B-3cp7A:
undetectable		 6f32B-3cp7A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvo METHYLTRANSFERASE-LI
KE PROTEIN OF
UNKNOWN FUNCTION

(Ruegeria
pomeroyi) 		no annotation 4 ASN A  82
VAL A  84
VAL A 113
THR A 116
 EDO  A 212 (-3.8A)
None
None
EDO  A 212 ( 3.9A)
 1.17A 6f32B-3cvoA:
3.4		 6f32B-3cvoA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dms ISOCITRATE
DEHYDROGENASE [NADP]

(Burkholderia
pseudomallei) 		PF00180
(Iso_dh) 		4 TYR A 298
VAL A 278
VAL A 227
THR A 228
 None
 1.36A 6f32B-3dmsA:
undetectable		 6f32B-3dmsA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ecf NTF2-LIKE PROTEIN

(Trichormus
variabilis) 		PF16247
(DUF4904) 		4 TYR A  88
VAL A  55
VAL A  59
THR A  82
 None
UNL  A 200 ( 4.7A)
None
None
 1.09A 6f32B-3ecfA:
undetectable		 6f32B-3ecfA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fj7 MAJOR ANTIGENIC
PEPTIDE PEB3

(Campylobacter
jejuni) 		PF13531
(SBP_bac_11) 		4 TYR A 233
VAL A  49
VAL A  47
THR A  45
 None
 1.34A 6f32B-3fj7A:
undetectable		 6f32B-3fj7A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gms PUTATIVE
NADPH:QUINONE
REDUCTASE

(Bacillus
thuringiensis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 TYR A 190
VAL A 173
VAL A 203
THR A 202
 None
 1.38A 6f32B-3gmsA:
4.1		 6f32B-3gmsA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5p NUCLEOPORIN NUP170

(Saccharomyces
cerevisiae) 		PF03177
(Nucleoporin_C) 		4 TYR A1060
VAL A1051
VAL A1108
THR A1111
 None
 1.46A 6f32B-3i5pA:
undetectable		 6f32B-3i5pA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 4

(Thermus
thermophilus) 		PF00346
(Complex1_49kDa) 		4 ASN 4  78
TYR 4  81
VAL 4 368
THR 4  69
 None
 1.35A 6f32B-3i9v4:
undetectable		 6f32B-3i9v4:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j26 MINOR VIRION PROTEIN

(Mimivirus-dependent
virus Sputnik) 		no annotation 4 TYR N 130
VAL N 125
VAL N 127
THR N 128
 None
 1.32A 6f32B-3j26N:
undetectable		 6f32B-3j26N:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mml ALLOPHANATE
HYDROLASE SUBUNIT 2
ALLOPHANATE
HYDROLASE SUBUNIT 1

(Mycolicibacterium
smegmatis;
Mycolicibacterium
smegmatis) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		4 TYR B 134
VAL B  43
VAL A 254
THR A 255
 None
 1.33A 6f32B-3mmlB:
undetectable		 6f32B-3mmlB:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum) 		PF00106
(adh_short)
PF13561
(adh_short_C2) 		4 ASN A 177
TYR A 246
VAL A 159
THR A 160
 None
 1.40A 6f32B-3o26A:
4.5		 6f32B-3o26A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohn OUTER MEMBRANE USHER
PROTEIN FIMD

(Escherichia
coli) 		PF00577
(Usher) 		4 ASN A 149
TYR A 649
VAL A 151
THR A 263
 None
 1.36A 6f32B-3ohnA:
undetectable		 6f32B-3ohnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohn OUTER MEMBRANE USHER
PROTEIN FIMD

(Escherichia
coli) 		PF00577
(Usher) 		4 ASN A 165
TYR A 163
VAL A 266
THR A 267
 None
 1.30A 6f32B-3ohnA:
undetectable		 6f32B-3ohnA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oo9 ABC TRANSPORTER
BINDING PROTEIN ACBH

(Actinoplanes
sp. SE50/110) 		PF01547
(SBP_bac_1) 		4 TYR A 310
VAL A  49
VAL A  47
THR A  45
 None
 1.35A 6f32B-3oo9A:
undetectable		 6f32B-3oo9A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ASN A 231
TYR A  68
VAL A 209
VAL A 211
 None
 1.42A 6f32B-3szeA:
undetectable		 6f32B-3szeA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1

(Bos taurus) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF08282
(Hydrolase_3)
PF13246
(Cation_ATPase) 		4 ASN A 910
TYR A 762
VAL A 843
VAL A 768
 None
 1.30A 6f32B-3tlmA:
undetectable		 6f32B-3tlmA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uif SULFONATE ABC
TRANSPORTER,
PERIPLASMIC
SULFONATE-BINDING
PROTEIN SSUA

(Methylobacillus
flagellatus) 		PF09084
(NMT1) 		4 ASN A 269
TYR A 272
VAL A  44
VAL A  39
 None
 1.42A 6f32B-3uifA:
undetectable		 6f32B-3uifA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0l GLUCOKINASE

(Xenopus laevis) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 ASN A 197
VAL A 200
VAL A 246
THR A 248
 None
 1.37A 6f32B-3w0lA:
undetectable		 6f32B-3w0lA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wj9 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2A

(Schizosaccharomyces
pombe) 		PF08662
(eIF2A) 		4 TYR A 244
VAL A 195
VAL A 218
THR A 233
 None
 1.36A 6f32B-3wj9A:
undetectable		 6f32B-3wj9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zcw KINESIN-LIKE PROTEIN
KIF11

(Homo sapiens) 		PF00225
(Kinesin) 		4 ASN A  98
VAL A  93
VAL A 241
THR A 242
 None
 1.23A 6f32B-3zcwA:
undetectable		 6f32B-3zcwA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bqi ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC

(Arabidopsis
thaliana) 		PF00343
(Phosphorylase) 		4 ASN A 638
VAL A 650
VAL A 610
THR A 609
 None
 1.29A 6f32B-4bqiA:
undetectable		 6f32B-4bqiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eyo EXTRACELLULAR
LIGAND-BINDING
RECEPTOR

(Rhodopseudomonas
palustris) 		PF13458
(Peripla_BP_6) 		4 ASN A 110
VAL A 106
VAL A 127
THR A 128
 None
 1.27A 6f32B-4eyoA:
undetectable		 6f32B-4eyoA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fn5 ELONGATION FACTOR G
1

(Pseudomonas
aeruginosa) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF03764
(EFG_IV)
PF14492
(EFG_II) 		4 VAL A 353
LYS A 354
VAL A 391
THR A 392
 None
 1.41A 6f32B-4fn5A:
undetectable		 6f32B-4fn5A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3n DNA GYRASE SUBUNIT A

(Mycobacterium
tuberculosis) 		PF03989
(DNA_gyraseA_C) 		4 TYR A 534
VAL A 560
VAL A 518
THR A 519
 None
 1.46A 6f32B-4g3nA:
undetectable		 6f32B-4g3nA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gx0 TRKA DOMAIN PROTEIN

(Geobacter
sulfurreducens) 		PF02080
(TrkA_C)
PF02254
(TrkA_N)
PF07885
(Ion_trans_2) 		4 TYR A 179
VAL A 177
VAL A 159
THR A 160
 None
 1.31A 6f32B-4gx0A:
5.1		 6f32B-4gx0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		4 ASN A 365
TYR A 363
VAL A 360
THR A 339
 None
 1.43A 6f32B-4hwvA:
undetectable		 6f32B-4hwvA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu2 CELLULOSE-BINDING
PROTEIN

(Ruminococcus
flavefaciens) 		no annotation 4 TYR B 118
VAL B  21
VAL B 115
THR B 116
 None
 1.45A 6f32B-4iu2B:
undetectable		 6f32B-4iu2B:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kcd GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 3A

(Rattus
norvegicus) 		PF10613
(Lig_chan-Glu_bd) 		4 TYR A  97
VAL A  10
VAL A 121
THR A 122
 None
 1.26A 6f32B-4kcdA:
undetectable		 6f32B-4kcdA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ldc DOUBLE C2-LIKE
DOMAIN-CONTAINING
PROTEIN BETA

(Rattus
norvegicus) 		PF00168
(C2) 		4 TYR A 309
VAL A 371
VAL A 353
THR A 354
 None
 1.42A 6f32B-4ldcA:
undetectable		 6f32B-4ldcA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lr2 BIS(5'-ADENOSYL)-TRI
PHOSPHATASE ENPP4

(Homo sapiens) 		PF01663
(Phosphodiest) 		4 ASN A 386
TYR A 304
VAL A 368
VAL A  65
 NAG  A 501 (-1.8A)
NAG  A 501 (-4.3A)
None
None
 1.38A 6f32B-4lr2A:
undetectable		 6f32B-4lr2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lvo SUBTILISIN-LIKE
SERINE PROTEASE

(Plasmodium
falciparum) 		PF00082
(Peptidase_S8) 		4 TYR A 580
VAL A 553
VAL A 549
THR A 548
 None
 1.33A 6f32B-4lvoA:
undetectable		 6f32B-4lvoA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m8r HYPOTHETICAL PROTEIN

(Bacteroides
caccae) 		PF16023
(DUF4784) 		4 TYR A 429
VAL A 440
VAL A 405
THR A 404
 None
 1.01A 6f32B-4m8rA:
undetectable		 6f32B-4m8rA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6z SERINE
HYDROXYMETHYLTRANSFE
RASE

(Plasmodium
falciparum) 		PF00464
(SHMT) 		4 ASN A 156
TYR A 160
VAL A 319
THR A 320
 None
 1.37A 6f32B-4o6zA:
undetectable		 6f32B-4o6zA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oud TYROSYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00579
(tRNA-synt_1b) 		5 ASN B 125
TYR B 127
VAL B 101
VAL B  97
THR B  96
 ASN  B 125 ( 0.6A)
TYR  B 127 ( 1.3A)
VAL  B 101 ( 0.6A)
VAL  B  97 ( 0.6A)
THR  B  96 ( 0.8A)
 1.46A 6f32B-4oudB:
2.9		 6f32B-4oudB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ov6 PROPROTEIN
CONVERTASE
SUBTILISIN/KEXIN
TYPE 9

(Homo sapiens) 		PF00082
(Peptidase_S8) 		4 TYR B 183
VAL B 200
VAL B 202
THR B 203
 None
 1.45A 6f32B-4ov6B:
undetectable		 6f32B-4ov6B:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pju COHESIN SUBUNIT SA-2

(Homo sapiens) 		PF08514
(STAG) 		4 ASN A 412
VAL A 376
LYS A 372
THR A 406
 None
 1.37A 6f32B-4pjuA:
undetectable		 6f32B-4pjuA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5t LIPOPROTEIN

(Streptococcus
mutans) 		PF03180
(Lipoprotein_9) 		4 ASN A  93
TYR A  89
VAL A 104
THR A 105
 None
 1.20A 6f32B-4q5tA:
undetectable		 6f32B-4q5tA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqo METHANOL
DEHYDROGENASE
PROTEIN, LARGE
SUBUNIT

(Methylococcus
capsulatus) 		no annotation 4 TYR B 401
VAL B 382
LYS B 377
VAL B 385
 None
 1.44A 6f32B-4tqoB:
undetectable		 6f32B-4tqoB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y4r BIFUNCTIONAL
LYSINE-SPECIFIC
DEMETHYLASE AND
HISTIDYL-HYDROXYLASE
NO66

(Homo sapiens) 		PF08007
(Cupin_4) 		4 TYR A 615
VAL A 596
VAL A 536
THR A 622
 None
 1.41A 6f32B-4y4rA:
undetectable		 6f32B-4y4rA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y93 NON-SPECIFIC
PROTEIN-TYROSINE
KINASE,NON-SPECIFIC
PROTEIN-TYROSINE
KINASE

(Bos taurus) 		PF00169
(PH)
PF00779
(BTK)
PF07714
(Pkinase_Tyr) 		4 ASN A 135
TYR A 134
VAL A  58
VAL A  34
 None
 1.26A 6f32B-4y93A:
undetectable		 6f32B-4y93A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zk6 QUINOLINATE SYNTHASE
A

(Pyrococcus
horikoshii) 		PF02445
(NadA) 		4 ASN A 128
VAL A 132
VAL A 107
THR A 123
 None
 1.43A 6f32B-4zk6A:
undetectable		 6f32B-4zk6A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
MOLYBDOPTERIN-BINDIN
G SUBUNIT

(Sulfurisphaera
tokodaii) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 TYR A 588
VAL A 406
VAL A 408
THR A 681
 None
 1.35A 6f32B-4zohA:
undetectable		 6f32B-4zohA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		4 TYR A 102
VAL A  29
VAL A  96
THR A  97
 None
 1.38A 6f32B-5a29A:
undetectable		 6f32B-5a29A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6b N-ACETYL-BETA-D-GLUC
OSAMINIDASE

(Streptococcus
pneumoniae) 		PF00728
(Glyco_hydro_20) 		4 TYR D 308
VAL D 368
VAL D 370
THR D 371
 OAN  D1627 (-4.3A)
None
None
None
 1.33A 6f32B-5a6bD:
undetectable		 6f32B-5a6bD:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e37 EF-HAND
DOMAIN-CONTAINING
THIOREDOXIN

(Chlamydomonas
reinhardtii) 		PF00085
(Thioredoxin)
PF13499
(EF-hand_7) 		4 ASN A 224
VAL A 260
VAL A 262
THR A 209
 ASN  A 224 ( 0.6A)
VAL  A 260 ( 0.6A)
VAL  A 262 ( 0.5A)
THR  A 209 ( 0.9A)
 1.26A 6f32B-5e37A:
undetectable		 6f32B-5e37A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e5u RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE GAMMA
CONTACTIN-6

(Mus musculus;
Mus musculus) 		PF00194
(Carb_anhydrase)
PF13927
(Ig_3) 		4 ASN A 119
LYS B 228
VAL A 299
THR A 290
 None
 1.41A 6f32B-5e5uA:
undetectable		 6f32B-5e5uA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fm2 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 TYR A 752
VAL A 725
VAL A 755
THR A 754
 None
 1.34A 6f32B-5fm2A:
undetectable		 6f32B-5fm2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT ZETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		4 TYR z 355
VAL z 214
VAL z 367
THR z 368
 None
 1.44A 6f32B-5gw5z:
undetectable		 6f32B-5gw5z:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h53 SKELETAL MUSCLE
MYOSIN HEAVY CHAIN
MYHC-EO/IIL

(Oryctolagus
cuniculus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		4 ASN A 625
TYR A 626
VAL A 442
THR A 443
 None
 1.34A 6f32B-5h53A:
undetectable		 6f32B-5h53A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kjz CAMP-DEPENDENT
PROTEIN KINASE TYPE
I-ALPHA REGULATORY
SUBUNIT

(Homo sapiens) 		PF00027
(cNMP_binding) 		4 ASN A 374
TYR A 373
VAL A 377
VAL A 315
 GOL  A 402 (-4.2A)
PCG  A 401 (-3.8A)
None
PCG  A 401 (-4.5A)
 1.04A 6f32B-5kjzA:
undetectable		 6f32B-5kjzA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l51 (-)-MENTHONE:(+)-NEO
MENTHOL REDUCTASE

(Mentha x
piperita) 		PF00106
(adh_short)
PF13561
(adh_short_C2) 		4 ASN A 185
TYR A 254
VAL A 167
THR A 168
 None
 1.42A 6f32B-5l51A:
4.4		 6f32B-5l51A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tfl CADHERIN-23

(Mus musculus) 		no annotation 4 TYR A 760
VAL A 855
VAL A 774
THR A 775
 None
 1.37A 6f32B-5tflA:
undetectable		 6f32B-5tflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tro PENICILLIN-BINDING
PROTEIN 1

(Staphylococcus
aureus) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 ASN A 532
TYR A 566
VAL A 536
THR A 516
 None
 1.25A 6f32B-5troA:
undetectable		 6f32B-5troA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tv2 ELONGATION FACTOR G

(Vibrio
vulnificus) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 VAL A 351
LYS A 352
VAL A 389
THR A 390
 None
 1.14A 6f32B-5tv2A:
undetectable		 6f32B-5tv2A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ty0 ELONGATION FACTOR G

(Legionella
pneumophila) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 VAL A 349
LYS A 350
VAL A 387
THR A 388
 None
 1.14A 6f32B-5ty0A:
undetectable		 6f32B-5ty0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wze AMINOPEPTIDASE P

(Pseudomonas
aeruginosa) 		no annotation 4 ASN A 297
VAL A 383
VAL A 420
THR A 422
 None
 1.28A 6f32B-5wzeA:
undetectable		 6f32B-5wzeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmr SERINE
HYDROXYMETHYLTRANSFE
RASE

(Plasmodium
vivax) 		no annotation 4 ASN A 156
TYR A 160
VAL A 319
THR A 320
 None
 1.35A 6f32B-5xmrA:
undetectable		 6f32B-5xmrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt7 -

(-) 		no annotation 4 ASN A  66
TYR A  91
VAL A  68
VAL A  79
 None
 1.42A 6f32B-5yt7A:
undetectable		 6f32B-5yt7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f34 AMINO ACID
TRANSPORTER

(Geobacillus
kaustophilus) 		no annotation 4 ASN A 184
VAL A 188
LYS A 191
THR A 316
 None
 1.46A 6f32B-6f34A:
undetectable		 6f32B-6f34A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 ASN A1794
TYR A1808
LYS A2055
VAL A2076
 None
 1.39A 6f32B-6fb3A:
undetectable		 6f32B-6fb3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fg9 -

(-) 		no annotation 4 TYR A 273
VAL A 246
VAL A 250
THR A 267
 None
 1.38A 6f32B-6fg9A:
undetectable		 6f32B-6fg9A:
undetectable