SIMILAR PATTERNS OF AMINO ACIDS FOR 6EXI_B_ADNB502

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n11 ANKYRIN

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		5 HIS A 673
GLN A 644
ASN A 665
LEU A 669
HIS A 640
 None
 1.40A 6exiB-1n11A:
undetectable		 6exiB-1n11A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v8b ADENOSYLHOMOCYSTEINA
SE

(Plasmodium
falciparum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		9 HIS A  54
THR A  56
LYS A 230
ASP A 234
ASN A 391
LEU A 392
HIS A 398
MET A 403
PHE A 407
 ADN  A 502 (-4.1A)
ADN  A 502 (-3.0A)
ADN  A 502 (-3.0A)
ADN  A 502 (-2.8A)
NAD  A 501 (-3.0A)
ADN  A 502 ( 4.9A)
ADN  A 502 ( 3.5A)
ADN  A 502 (-3.6A)
None
 0.71A 6exiB-1v8bA:
55.2		 6exiB-1v8bA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus) 		PF00343
(Phosphorylase) 		5 THR A 671
THR A 668
ASN A 284
LEU A 380
HIS A 571
 None
 1.16A 6exiB-2gj4A:
2.3		 6exiB-2gj4A:
7.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  69
THR A  71
GLN A  73
THR A  74
HIS A 363
LEU A 410
PHE A 425
 ADN  A 500 (-4.0A)
ADN  A 500 (-2.8A)
ADN  A 500 (-3.6A)
ADN  A 500 (-4.5A)
ADN  A 500 ( 3.7A)
ADN  A 500 ( 4.8A)
ADN  A 500 (-4.8A)
 1.03A 6exiB-3ce6A:
55.7		 6exiB-3ce6A:
60.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  69
THR A  71
GLN A  73
THR A  74
LYS A 248
ASP A 252
ASN A 409
LEU A 410
HIS A 416
MET A 421
PHE A 425
 ADN  A 500 (-4.0A)
ADN  A 500 (-2.8A)
ADN  A 500 (-3.6A)
ADN  A 500 (-4.5A)
ADN  A 500 (-2.8A)
ADN  A 500 (-2.7A)
NAD  A 550 (-3.0A)
ADN  A 500 ( 4.8A)
ADN  A 500 ( 3.6A)
ADN  A 500 (-3.7A)
ADN  A 500 (-4.8A)
 0.66A 6exiB-3ce6A:
55.7		 6exiB-3ce6A:
60.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g1u ADENOSYLHOMOCYSTEINA
SE

(Leishmania
major) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		9 HIS A  52
THR A  54
GLN A  56
THR A  57
ASN A 345
LEU A 346
HIS A 352
MET A 357
PHE A 361
 ADN  A 438 (-4.0A)
ADN  A 438 (-2.8A)
ADN  A 438 (-3.8A)
ADN  A 438 (-4.6A)
NAD  A 439 (-3.1A)
ADN  A 438 ( 4.8A)
ADN  A 438 ( 3.6A)
ADN  A 438 (-3.7A)
None
 0.18A 6exiB-3g1uA:
53.6		 6exiB-3g1uA:
71.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g1u ADENOSYLHOMOCYSTEINA
SE

(Leishmania
major) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  52
THR A  54
GLN A  56
THR A  57
HIS A 300
LEU A 346
PHE A 361
 ADN  A 438 (-4.0A)
ADN  A 438 (-2.8A)
ADN  A 438 (-3.8A)
ADN  A 438 (-4.6A)
ADN  A 438 ( 4.0A)
ADN  A 438 ( 4.8A)
None
 1.05A 6exiB-3g1uA:
53.6		 6exiB-3g1uA:
71.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3glq ADENOSYLHOMOCYSTEINA
SE

(Burkholderia
pseudomallei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  62
THR A  64
GLN A  66
THR A  67
HIS A 344
LEU A 388
PHE A 403
 RAB  A 602 (-3.8A)
RAB  A 602 (-2.7A)
RAB  A 602 (-3.9A)
RAB  A 602 (-4.5A)
RAB  A 602 ( 3.5A)
RAB  A 602 ( 4.7A)
None
 1.03A 6exiB-3glqA:
59.0		 6exiB-3glqA:
61.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3glq ADENOSYLHOMOCYSTEINA
SE

(Burkholderia
pseudomallei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  62
THR A  64
GLN A  66
THR A  67
LYS A 229
ASP A 233
ASN A 387
LEU A 388
HIS A 394
MET A 399
PHE A 403
 RAB  A 602 (-3.8A)
RAB  A 602 (-2.7A)
RAB  A 602 (-3.9A)
RAB  A 602 (-4.5A)
RAB  A 602 (-3.0A)
RAB  A 602 (-2.5A)
NAD  A 601 (-3.0A)
RAB  A 602 ( 4.7A)
NAD  A 601 ( 3.6A)
RAB  A 602 (-3.6A)
None
 0.64A 6exiB-3glqA:
59.0		 6exiB-3glqA:
61.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3gvp ADENOSYLHOMOCYSTEINA
SE 3

(Homo sapiens) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 HIS A 234
THR A 236
GLN A 238
THR A 239
LYS A 365
 None
 0.63A 6exiB-3gvpA:
42.6		 6exiB-3gvpA:
51.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9u ADENOSYLHOMOCYSTEINA
SE

(Trypanosoma
brucei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  52
THR A  54
GLN A  56
THR A  57
HIS A 300
LEU A 346
PHE A 361
 ADN  A 439 ( 4.7A)
ADN  A 439 (-2.7A)
ADN  A 439 (-3.6A)
ADN  A 439 (-4.7A)
None
ADN  A 439 ( 4.7A)
None
 1.05A 6exiB-3h9uA:
55.1		 6exiB-3h9uA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9u ADENOSYLHOMOCYSTEINA
SE

(Trypanosoma
brucei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  52
THR A  54
GLN A  56
THR A  57
LYS A 185
ASP A 189
ASN A 345
LEU A 346
HIS A 352
MET A 357
PHE A 361
 ADN  A 439 ( 4.7A)
ADN  A 439 (-2.7A)
ADN  A 439 (-3.6A)
ADN  A 439 (-4.7A)
NAD  A 438 ( 3.9A)
NAD  A 438 ( 4.4A)
NAD  A 438 (-2.9A)
ADN  A 439 ( 4.7A)
ADN  A 439 ( 3.3A)
ADN  A 439 ( 3.7A)
None
 0.70A 6exiB-3h9uA:
55.1		 6exiB-3h9uA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hv0 TRYPTOPHANYL-TRNA
SYNTHETASE

(Cryptosporidium
parvum) 		PF00579
(tRNA-synt_1b) 		5 THR A 305
GLN A 245
THR A 243
LEU A 302
HIS A 248
 None
 1.44A 6exiB-3hv0A:
2.6		 6exiB-3hv0A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n58 ADENOSYLHOMOCYSTEINA
SE

(Brucella
abortus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  55
THR A  57
GLN A  59
THR A  60
HIS A 337
LEU A 381
PHE A 396
 ADN  A 500 (-4.0A)
ADN  A 500 (-2.8A)
K  A   2 ( 3.3A)
ADN  A 500 (-4.6A)
ADN  A 500 ( 3.6A)
ADN  A 500 ( 4.8A)
None
 1.04A 6exiB-3n58A:
60.1		 6exiB-3n58A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n58 ADENOSYLHOMOCYSTEINA
SE

(Brucella
abortus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  55
THR A  57
GLN A  59
THR A  60
LYS A 222
ASP A 226
ASN A 380
LEU A 381
HIS A 387
MET A 392
PHE A 396
 ADN  A 500 (-4.0A)
ADN  A 500 (-2.8A)
K  A   2 ( 3.3A)
ADN  A 500 (-4.6A)
ADN  A 500 (-2.7A)
ADN  A 500 ( 2.6A)
NAD  A 550 (-3.0A)
ADN  A 500 ( 4.8A)
ADN  A 500 (-3.4A)
ADN  A 500 (-3.7A)
None
 0.65A 6exiB-3n58A:
60.1		 6exiB-3n58A:
14.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3one ADENOSYLHOMOCYSTEINA
SE

(Lupinus luteus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  62
THR A  64
GLN A  66
THR A  67
HIS A 350
LEU A 398
PHE A 413
 ADE  A 506 (-4.6A)
ADE  A 506 (-2.8A)
ADE  A 506 (-3.8A)
ADE  A 506 (-4.5A)
None
ADE  A 506 ( 4.7A)
ADE  A 506 (-4.9A)
 1.07A 6exiB-3oneA:
55.4		 6exiB-3oneA:
64.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3one ADENOSYLHOMOCYSTEINA
SE

(Lupinus luteus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  62
THR A  64
GLN A  66
THR A  67
LYS A 235
ASP A 239
ASN A 397
LEU A 398
HIS A 404
MET A 409
PHE A 413
 ADE  A 506 (-4.6A)
ADE  A 506 (-2.8A)
ADE  A 506 (-3.8A)
ADE  A 506 (-4.5A)
NAD  A 501 ( 4.2A)
NAD  A 501 ( 4.5A)
NAD  A 501 (-3.0A)
ADE  A 506 ( 4.7A)
ADE  A 506 (-3.4A)
ADE  A 506 (-3.8A)
ADE  A 506 (-4.9A)
 0.67A 6exiB-3oneA:
55.4		 6exiB-3oneA:
64.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lvc S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE)

(Bradyrhizobium
elkanii) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  58
THR A  60
GLN A  62
THR A  63
HIS A 342
LEU A 386
PHE A 401
 ADN  A 501 (-4.0A)
ADN  A 501 (-2.8A)
NH4  A 502 ( 3.1A)
ADN  A 501 (-4.5A)
ADN  A 501 ( 3.7A)
ADN  A 501 ( 4.7A)
ADN  A 501 (-4.8A)
 1.05A 6exiB-4lvcA:
63.5		 6exiB-4lvcA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lvc S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE)

(Bradyrhizobium
elkanii) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  58
THR A  60
GLN A  62
THR A  63
LYS A 227
ASP A 231
ASN A 385
LEU A 386
HIS A 392
MET A 397
PHE A 401
 ADN  A 501 (-4.0A)
ADN  A 501 (-2.8A)
NH4  A 502 ( 3.1A)
ADN  A 501 (-4.5A)
ADN  A 501 (-2.7A)
ADN  A 501 (-3.1A)
NAD  A 503 (-3.1A)
ADN  A 501 ( 4.7A)
ADN  A 501 (-3.5A)
ADN  A 501 (-3.7A)
ADN  A 501 (-4.8A)
 0.64A 6exiB-4lvcA:
63.5		 6exiB-4lvcA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5

(Sus scrofa) 		PF00149
(Metallophos) 		5 HIS A 195
THR A 198
ASP A  14
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 ( 3.1A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.30A 6exiB-5uq6A:
undetectable		 6exiB-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uq6 TARTRATE-RESISTANT
ACID PHOSPHATASE
TYPE 5

(Sus scrofa) 		PF00149
(Metallophos) 		5 HIS A 195
THR A 198
HIS A 223
ASN A  91
HIS A 186
 PO4  A 404 (-3.8A)
None
FE  A 402 (-3.4A)
PO4  A 404 ( 2.6A)
FE  A 403 ( 3.4A)
 1.34A 6exiB-5uq6A:
undetectable		 6exiB-5uq6A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5utu ADENOSYLHOMOCYSTEINA
SE

(Cryptosporidium
parvum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		10 HIS A  53
THR A  55
THR A  58
LYS A 241
ASP A 245
ASN A 403
LEU A 404
HIS A 410
MET A 415
PHE A 419
 SAH  A 502 (-4.0A)
SAH  A 502 (-2.7A)
SAH  A 502 (-4.2A)
SAH  A 502 (-2.9A)
SAH  A 502 (-2.8A)
NAD  A 501 (-2.9A)
SAH  A 502 ( 4.7A)
SAH  A 502 ( 3.5A)
SAH  A 502 (-3.6A)
SAH  A 502 (-4.8A)
 0.73A 6exiB-5utuA:
52.7		 6exiB-5utuA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v96 S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE

(Naegleria
fowleri) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		10 HIS A  59
THR A  61
THR A  64
LYS A 227
ASP A 231
ASN A 388
LEU A 389
HIS A 395
MET A 400
PHE A 404
 ADN  A 502 ( 3.9A)
ADN  A 502 (-2.9A)
ADN  A 502 (-4.4A)
ADN  A 502 (-2.9A)
ADN  A 502 (-2.8A)
NAD  A 501 (-3.1A)
ADN  A 502 ( 4.7A)
ADN  A 502 ( 3.4A)
ADN  A 502 (-3.8A)
ADN  A 502 (-4.9A)
 0.69A 6exiB-5v96A:
56.7		 6exiB-5v96A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4b ADENOSYLHOMOCYSTEINA
SE

(Homo sapiens) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  55
THR A  57
THR A  60
LYS A 186
ASP A 190
MET A 358
PHE A 362
 9W4  A 502 (-3.7A)
9W4  A 502 (-2.9A)
None
None
NAD  A 501 (-4.1A)
9W4  A 502 (-3.6A)
None
 1.16A 6exiB-5w4bA:
47.5		 6exiB-5w4bA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4b ADENOSYLHOMOCYSTEINA
SE

(Homo sapiens) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 LYS A 186
ASP A 190
ASN A 346
LEU A 344
HIS A 353
 None
NAD  A 501 (-4.1A)
NAD  A 501 (-3.1A)
NAD  A 501 (-4.0A)
NAD  A 501 (-4.5A)
 1.35A 6exiB-5w4bA:
47.5		 6exiB-5w4bA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4b ADENOSYLHOMOCYSTEINA
SE

(Homo sapiens) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		6 LYS A 186
ASP A 190
ASN A 346
LEU A 347
HIS A 353
MET A 358
 None
NAD  A 501 (-4.1A)
NAD  A 501 (-3.1A)
9W4  A 502 (-4.1A)
NAD  A 501 (-4.5A)
9W4  A 502 (-3.6A)
 1.12A 6exiB-5w4bA:
47.5		 6exiB-5w4bA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w4b ADENOSYLHOMOCYSTEINA
SE

(Homo sapiens) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		6 THR A  60
LYS A 186
ASP A 190
HIS A 353
MET A 358
PHE A 362
 None
None
NAD  A 501 (-4.1A)
NAD  A 501 (-4.5A)
9W4  A 502 (-3.6A)
None
 1.32A 6exiB-5w4bA:
47.5		 6exiB-5w4bA:
12.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6aph ADENOSYLHOMOCYSTEINA
SE

(Elizabethkingia
anophelis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		7 HIS A  58
THR A  60
GLN A  62
THR A  63
HIS A 306
LEU A 352
PHE A 367
 ADN  A 501 (-3.9A)
ADN  A 501 (-2.8A)
ADN  A 501 (-3.8A)
ADN  A 501 (-4.5A)
ADN  A 501 ( 3.7A)
ADN  A 501 ( 4.8A)
None
 1.04A 6exiB-6aphA:
29.7		 6exiB-6aphA:
69.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6aph ADENOSYLHOMOCYSTEINA
SE

(Elizabethkingia
anophelis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		11 HIS A  58
THR A  60
GLN A  62
THR A  63
LYS A 191
ASP A 195
ASN A 351
LEU A 352
HIS A 358
MET A 363
PHE A 367
 ADN  A 501 (-3.9A)
ADN  A 501 (-2.8A)
ADN  A 501 (-3.8A)
ADN  A 501 (-4.5A)
ADN  A 501 (-2.8A)
ADN  A 501 (-2.7A)
NAD  A 500 (-3.1A)
ADN  A 501 ( 4.8A)
ADN  A 501 ( 3.5A)
ADN  A 501 (-3.7A)
None
 0.65A 6exiB-6aphA:
29.7		 6exiB-6aphA:
69.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3m -

(-) 		no annotation 7 HIS B  61
THR B  63
GLN B  65
THR B  66
HIS B 323
LEU B 376
PHE B 391
 ADN  B 502 ( 4.0A)
ADN  B 502 (-2.8A)
K  B 504 ( 3.0A)
ADN  B 502 (-4.6A)
ZN  B 505 (-3.2A)
ADN  B 502 ( 4.8A)
ADN  B 502 (-4.9A)
 1.01A 6exiB-6f3mB:
51.2		 6exiB-6f3mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3m -

(-) 		no annotation 11 HIS B  61
THR B  63
GLN B  65
THR B  66
LYS B 194
ASP B 198
ASN B 375
LEU B 376
HIS B 382
MET B 387
PHE B 391
 ADN  B 502 ( 4.0A)
ADN  B 502 (-2.8A)
K  B 504 ( 3.0A)
ADN  B 502 (-4.6A)
ADN  B 502 (-2.8A)
ADN  B 502 (-2.7A)
NAD  B 501 (-3.0A)
ADN  B 502 ( 4.8A)
ADN  B 502 (-3.4A)
ADN  B 502 (-3.7A)
ADN  B 502 (-4.9A)
 0.68A 6exiB-6f3mB:
51.2		 6exiB-6f3mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-) 		no annotation 7 HIS A  56
THR A  58
GLN A  60
THR A  61
HIS A 304
LEU A 350
PHE A 365
 ADN  A 501 (-3.9A)
ADN  A 501 (-2.8A)
NA  A 503 ( 3.2A)
ADN  A 501 (-4.6A)
ADN  A 501 ( 3.6A)
ADN  A 501 ( 4.7A)
None
 1.03A 6exiB-6gbnA:
31.6		 6exiB-6gbnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-) 		no annotation 11 HIS A  56
THR A  58
GLN A  60
THR A  61
LYS A 189
ASP A 193
ASN A 349
LEU A 350
HIS A 356
MET A 361
PHE A 365
 ADN  A 501 (-3.9A)
ADN  A 501 (-2.8A)
NA  A 503 ( 3.2A)
ADN  A 501 (-4.6A)
ADN  A 501 (-2.9A)
ADN  A 501 (-2.7A)
NAD  A 502 (-3.1A)
ADN  A 501 ( 4.7A)
ADN  A 501 (-3.4A)
ADN  A 501 (-3.6A)
None
 0.65A 6exiB-6gbnA:
31.6		 6exiB-6gbnA:
undetectable