SIMILAR PATTERNS OF AMINO ACIDS FOR 6EU9_D_READ601

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bsg BETA LACTAMASE

(Streptomyces
albus) 		PF13354
(Beta-lactamase2) 		4 VAL A 279
LEU A 231
GLY A  45
GLY A 248
 None
 0.78A 6eu9D-1bsgA:
0.0		 6eu9D-1bsgA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ci9 PROTEIN
(CARBOXYLESTERASE)

(Burkholderia
gladioli) 		PF00144
(Beta-lactamase) 		4 VAL A 204
GLY A 273
LEU A  73
GLY A 279
 None
 0.68A 6eu9D-1ci9A:
0.0		 6eu9D-1ci9A:
12.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1exx RETINOIC ACID
RECEPTOR GAMMA-2

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 LEU A 268
PHE A 288
LEU A 294
LEU A 307
GLY A 393
 961  A 450 ( 4.9A)
961  A 450 (-4.6A)
None
961  A 450 (-4.8A)
961  A 450 ( 4.0A)
 0.60A 6eu9D-1exxA:
28.9		 6eu9D-1exxA:
43.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fc4 2-AMINO-3-KETOBUTYRA
TE CONENZYME A
LIGASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 VAL A 288
LEU A 277
GLY A 216
GLY A 251
 None
 0.75A 6eu9D-1fc4A:
0.0		 6eu9D-1fc4A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvh FLAVOHEMOPROTEIN

(Escherichia
coli) 		PF00042
(Globin)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 LEU A 345
LEU A 275
GLY A 270
LEU A 361
 None
 0.81A 6eu9D-1gvhA:
0.6		 6eu9D-1gvhA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hvy THYMIDYLATE SYNTHASE

(Homo sapiens) 		PF00303
(Thymidylat_synt) 		4 VAL A 134
LEU A 118
GLY A  94
GLY A 129
 None
 0.80A 6eu9D-1hvyA:
0.0		 6eu9D-1hvyA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pqu ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Haemophilus
influenzae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A  16
LEU A 328
GLY A 326
GLY A 167
 None
None
None
CYS  A1374 (-3.1A)
 0.71A 6eu9D-1pquA:
0.0		 6eu9D-1pquA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqj FUMARYLACETOACETATE
HYDROLASE

(Mus musculus) 		PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N) 		4 LEU A  67
PHE A  50
LEU A  88
GLY A  20
 None
 0.80A 6eu9D-1qqjA:
undetectable		 6eu9D-1qqjA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1siq GLUTARYL-COA
DEHYDROGENASE

(Homo sapiens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 PHE A 133
LEU A 246
GLY A 240
GLY A 112
 None
 0.78A 6eu9D-1siqA:
undetectable		 6eu9D-1siqA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wde PROBABLE DIPHTHINE
SYNTHASE

(Aeropyrum
pernix) 		PF00590
(TP_methylase) 		4 VAL A 240
GLY A 243
LEU A 182
GLY A 187
 None
 0.62A 6eu9D-1wdeA:
undetectable		 6eu9D-1wdeA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xew SMC PROTEIN

(Pyrococcus
furiosus) 		PF02463
(SMC_N) 		4 LEU X 127
PHE Y1093
GLY X  43
GLY X  52
 None
 0.80A 6eu9D-1xewX:
undetectable		 6eu9D-1xewX:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xv2 HYPOTHETICAL
PROTEIN, SIMILAR TO
ALPHA-ACETOLACTATE
DECARBOXYLASE

(Staphylococcus
aureus) 		PF03306
(AAL_decarboxy) 		4 PHE A  48
LEU A  29
GLY A  67
GLY A  21
 None
 0.76A 6eu9D-1xv2A:
undetectable		 6eu9D-1xv2A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z2i MALATE DEHYDROGENASE

(Agrobacterium
tumefaciens) 		PF02615
(Ldh_2) 		5 PHE A 343
LEU A  58
GLY A  54
LEU A  14
GLY A 332
 None
 1.49A 6eu9D-1z2iA:
undetectable		 6eu9D-1z2iA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aeu HYPOTHETICAL PROTEIN
MJ0158

(Methanocaldococcus
jannaschii) 		PF03841
(SelA) 		4 PHE A 176
GLY A 216
LEU A 237
GLY A 232
 None
 0.74A 6eu9D-2aeuA:
undetectable		 6eu9D-2aeuA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1f THREONINE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00291
(PALP) 		4 VAL A 235
LEU A 224
GLY A 230
GLY A 305
 None
 0.67A 6eu9D-2d1fA:
undetectable		 6eu9D-2d1fA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dgk GLUTAMATE
DECARBOXYLASE BETA

(Escherichia
coli) 		PF00282
(Pyridoxal_deC) 		4 PHE A 331
LEU A 107
GLY A 248
GLY A 125
 None
None
None
PLP  A1500 (-3.5A)
 0.72A 6eu9D-2dgkA:
undetectable		 6eu9D-2dgkA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Staphylococcus
aureus) 		PF01425
(Amidase) 		4 LEU A 122
GLY A  73
LEU A 118
GLY A 120
 None
 0.79A 6eu9D-2f2aA:
undetectable		 6eu9D-2f2aA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp4 6-PHOSPHOGLUCONATE
DEHYDRATASE

(Shewanella
oneidensis) 		PF00920
(ILVD_EDD) 		4 VAL A 282
LEU A  24
GLY A 315
GLY A 164
 None
 0.69A 6eu9D-2gp4A:
undetectable		 6eu9D-2gp4A:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxd DCTP DEAMINASE,
DUMP-FORMING

(Methanocaldococcus
jannaschii) 		PF00692
(dUTPase) 		4 LEU A 106
PHE A  22
GLY A  28
LEU A   3
 None
 0.67A 6eu9D-2hxdA:
undetectable		 6eu9D-2hxdA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k7q FILAMIN-A

(Homo sapiens) 		PF00630
(Filamin) 		4 VAL A2050
LEU A2057
GLY A2079
LEU A2082
 None
 0.65A 6eu9D-2k7qA:
undetectable		 6eu9D-2k7qA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lpv FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Aedes aegypti) 		PF00254
(FKBP_C) 		4 LEU A  31
GLY A  29
LEU A  75
GLY A  59
 None
 0.81A 6eu9D-2lpvA:
undetectable		 6eu9D-2lpvA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rgj FLAVIN-CONTAINING
MONOOXYGENASE

(Pseudomonas
aeruginosa) 		PF01494
(FAD_binding_3) 		4 VAL A  31
LEU A 308
GLY A  27
GLY A 330
 None
 0.75A 6eu9D-2rgjA:
undetectable		 6eu9D-2rgjA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6r IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
SUBUNIT HISF

(Thermotoga
maritima) 		PF00977
(His_biosynth) 		4 VAL A  13
LEU A  31
GLY A  29
GLY A  24
 None
 0.71A 6eu9D-2w6rA:
undetectable		 6eu9D-2w6rA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6r IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
SUBUNIT HISF

(Thermotoga
maritima) 		PF00977
(His_biosynth) 		4 VAL A 139
LEU A 157
GLY A 155
GLY A 150
 None
 0.76A 6eu9D-2w6rA:
undetectable		 6eu9D-2w6rA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w87 ESTERASE D

(Cellvibrio
japonicus) 		PF03422
(CBM_6) 		4 VAL A 118
LEU A 128
GLY A  87
GLY A  77
 None
 0.76A 6eu9D-2w87A:
undetectable		 6eu9D-2w87A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wxz ANGIOTENSINOGEN

(Rattus
norvegicus) 		PF00079
(Serpin) 		4 LEU A 128
PHE A 245
GLY A 194
LEU A 150
 None
 0.78A 6eu9D-2wxzA:
undetectable		 6eu9D-2wxzA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x50 TRYPANOTHIONE
REDUCTASE

(Leishmania
infantum) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 PHE A 114
GLY A  13
LEU A  10
GLY A 127
 None
FAD  A1487 (-3.1A)
None
FAD  A1487 (-3.6A)
 0.70A 6eu9D-2x50A:
undetectable		 6eu9D-2x50A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x8u SERINE
PALMITOYLTRANSFERASE

(Sphingomonas
wittichii) 		PF00155
(Aminotran_1_2) 		4 VAL A 240
LEU A 264
GLY A 120
GLY A 251
 None
 0.67A 6eu9D-2x8uA:
undetectable		 6eu9D-2x8uA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7c TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN

(Escherichia
coli) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 PHE B 401
LEU B 162
GLY B 411
LEU B 334
 None
 0.81A 6eu9D-2y7cB:
undetectable		 6eu9D-2y7cB:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a24 ALPHA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF10566
(Glyco_hydro_97)
PF14508
(GH97_N)
PF14509
(GH97_C) 		4 LEU A  32
PHE A 146
LEU A 229
GLY A 122
 None
 0.66A 6eu9D-3a24A:
undetectable		 6eu9D-3a24A:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus) 		PF00148
(Oxidored_nitro) 		4 VAL A 162
GLY A 231
LEU A 226
GLY A 177
 None
 0.79A 6eu9D-3aeuA:
undetectable		 6eu9D-3aeuA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agf GLUTAMINASE 1

(Bacillus
subtilis) 		PF04960
(Glutaminase) 		4 VAL A  78
LEU A 155
GLY A 218
GLY A 274
 None
 0.77A 6eu9D-3agfA:
undetectable		 6eu9D-3agfA:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aoe GLUTAMATE
DEHYDROGENASE

(Thermus
thermophilus) 		no annotation 4 VAL E 222
LEU E 275
GLY E 287
GLY E 252
 None
 0.78A 6eu9D-3aoeE:
undetectable		 6eu9D-3aoeE:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnj CHOLESTEROL OXIDASE

(Streptomyces
sp. SA-COO) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 VAL A 299
LEU A 287
GLY A 293
GLY A 317
 None
None
FAD  A 510 ( 4.0A)
None
 0.74A 6eu9D-3cnjA:
undetectable		 6eu9D-3cnjA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f9r PHOSPHOMANNOMUTASE

(Trypanosoma
brucei) 		PF03332
(PMM) 		4 LEU A   6
LEU A  72
GLY A  45
GLY A  41
 None
 0.80A 6eu9D-3f9rA:
undetectable		 6eu9D-3f9rA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0u PUTATIVE ENOYL-COA
HYDRATASE

(Streptomyces
avermitilis) 		PF00378
(ECH_1) 		4 PHE A 264
LEU A 274
GLY A 120
GLY A  36
 None
None
DMS  A   1 (-3.3A)
None
 0.78A 6eu9D-3h0uA:
undetectable		 6eu9D-3h0uA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3is5 CALCIUM-DEPENDENT
PROTEIN KINASE

(Toxoplasma
gondii) 		PF00069
(Pkinase) 		4 LEU A 374
PHE A 309
LEU A 341
GLY A 299
 None
 0.68A 6eu9D-3is5A:
undetectable		 6eu9D-3is5A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m49 TRANSKETOLASE

(Bacillus
anthracis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 242
PHE A  62
LEU A  73
GLY A  67
 None
 0.74A 6eu9D-3m49A:
undetectable		 6eu9D-3m49A:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3of7 REGULATOR OF
CHROMOSOME
CONDENSATION

(Saccharomyces
cerevisiae) 		PF00415
(RCC1)
PF13540
(RCC1_2) 		4 LEU A 143
LEU A  97
GLY A  92
GLY A  54
 None
 0.53A 6eu9D-3of7A:
undetectable		 6eu9D-3of7A:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oft CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 PHE A 206
GLY A 234
LEU A 170
GLY A 167
 None
HEM  A 417 (-4.0A)
None
None
 0.75A 6eu9D-3oftA:
undetectable		 6eu9D-3oftA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oft CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 PHE A 206
GLY A 235
LEU A 170
GLY A 167
 None
HEM  A 417 (-3.5A)
None
None
 0.75A 6eu9D-3oftA:
undetectable		 6eu9D-3oftA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzr ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Vibrio cholerae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A  15
LEU A 325
GLY A 323
GLY A 165
 None
None
None
CYS  A 371 (-3.4A)
 0.76A 6eu9D-3pzrA:
undetectable		 6eu9D-3pzrA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rqa PUTATIVE
UNCHARACTERIZED
PROTEIN

(Xanthomonas
campestris) 		PF16823
(PilZ_2) 		5 VAL A 101
LEU A 173
LEU A 154
GLY A  29
LEU A 138
 None
 1.23A 6eu9D-3rqaA:
undetectable		 6eu9D-3rqaA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqz PUTATIVE
HYDROXYMETHYLGLUTARY
L-COA SYNTHASE

(Streptococcus
mutans) 		PF00195
(Chal_sti_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 LEU A  63
LEU A 284
GLY A 156
LEU A 136
 None
 0.75A 6eu9D-3sqzA:
undetectable		 6eu9D-3sqzA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tat TYROSINE
AMINOTRANSFERASE

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 VAL A 133
LEU A 251
GLY A 151
GLY A 115
 None
 0.77A 6eu9D-3tatA:
undetectable		 6eu9D-3tatA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tdn FLR SYMMETRIC
ALPHA-BETA TIM
BARREL

(synthetic
construct) 		PF00977
(His_biosynth) 		4 VAL A  13
LEU A  31
GLY A  29
GLY A  24
 None
 0.73A 6eu9D-3tdnA:
undetectable		 6eu9D-3tdnA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uw3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Burkholderia
thailandensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A  15
LEU A 329
GLY A 327
GLY A 165
 None
EDO  A 374 ( 4.6A)
None
None
 0.77A 6eu9D-3uw3A:
undetectable		 6eu9D-3uw3A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vwa CYTOPLASMIC EXPORT
PROTEIN 1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 195
PHE A  98
LEU A 106
GLY A 112
 None
 0.66A 6eu9D-3vwaA:
undetectable		 6eu9D-3vwaA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w9u PUTATIVE LIPASE

(Proteus
mirabilis) 		PF00561
(Abhydrolase_1) 		4 LEU A  83
LEU A 245
GLY A 181
LEU A 176
 None
 0.76A 6eu9D-3w9uA:
undetectable		 6eu9D-3w9uA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wgc L-ALLO-THREONINE
ALDOLASE

(Aeromonas
jandaei) 		PF01212
(Beta_elim_lyase) 		4 VAL A 187
GLY A 169
LEU A 208
GLY A  45
 None
 0.63A 6eu9D-3wgcA:
undetectable		 6eu9D-3wgcA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af1 PEPTIDE CHAIN
RELEASE FACTOR
SUBUNIT 1

(Halobacterium
salinarum) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		4 LEU A 265
PHE A 237
GLY A 209
GLY A 161
 None
 0.76A 6eu9D-4af1A:
undetectable		 6eu9D-4af1A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amm DYNE8

(Micromonospora
chersina) 		PF00698
(Acyl_transf_1) 		4 PHE A 529
LEU A 543
GLY A 538
GLY A 561
 None
 0.80A 6eu9D-4ammA:
undetectable		 6eu9D-4ammA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbw SIALIDASE
(NEURAMINIDASE)

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 LEU A 156
GLY A 207
LEU A 216
GLY A 245
 None
 0.65A 6eu9D-4bbwA:
undetectable		 6eu9D-4bbwA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cp6 CHOLINE BINDING
PROTEIN PCPA

(Streptococcus
pneumoniae) 		PF13306
(LRR_5) 		4 LEU A 342
PHE A 381
GLY A 371
LEU A 324
 None
 0.79A 6eu9D-4cp6A:
undetectable		 6eu9D-4cp6A:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czb NA(+)/H(+)
ANTIPORTER 1

(Methanocaldococcus
jannaschii) 		PF00999
(Na_H_Exchanger) 		4 LEU A  92
GLY A 323
LEU A 101
GLY A 125
 None
 0.76A 6eu9D-4czbA:
undetectable		 6eu9D-4czbA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4j ARGININE DEIMINASE

(Mycoplasma
penetrans) 		PF02274
(Amidinotransf) 		4 LEU A 416
PHE A 426
LEU A 431
GLY A 436
 None
 0.79A 6eu9D-4e4jA:
undetectable		 6eu9D-4e4jA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj6 GLYCOSIDE HYDROLASE
FAMILY 33, CANDIDATE
SIALIDASE

(Parabacteroides
distasonis) 		PF13859
(BNR_3)
PF14873
(BNR_assoc_N) 		4 LEU A 153
GLY A 203
LEU A 212
GLY A 241
 None
 0.77A 6eu9D-4fj6A:
undetectable		 6eu9D-4fj6A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iql ENOYL-(ACYL-CARRIER-
PROTEIN) REDUCTASE
II

(Porphyromonas
gingivalis) 		PF03060
(NMO) 		4 LEU A 221
GLY A 142
LEU A 276
GLY A 274
 None
NA  A 407 (-4.0A)
None
None
 0.75A 6eu9D-4iqlA:
undetectable		 6eu9D-4iqlA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9u TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKH

(Vibrio
parahaemolyticus) 		PF02386
(TrkH) 		4 LEU A 134
LEU A  12
GLY A  50
GLY A  84
 None
 0.73A 6eu9D-4j9uA:
undetectable		 6eu9D-4j9uA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k5r OXYGENASE

(Streptomyces
argillaceus) 		PF01494
(FAD_binding_3) 		5 VAL A  16
LEU A 288
GLY A 164
LEU A 175
GLY A 136
 None
 1.23A 6eu9D-4k5rA:
undetectable		 6eu9D-4k5rA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kc5 RHIE PROTEIN

(Paraburkholderia
rhizoxinica) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 PHE A3441
LEU A3395
GLY A3365
GLY A3286
 None
 0.76A 6eu9D-4kc5A:
undetectable		 6eu9D-4kc5A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4obw 2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF01209
(Ubie_methyltran) 		4 VAL A 173
LEU A 154
GLY A 123
GLY A 165
 None
 0.77A 6eu9D-4obwA:
undetectable		 6eu9D-4obwA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4otd SERINE/THREONINE-PRO
TEIN KINASE N1

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		4 PHE A 623
LEU A 618
LEU A 652
GLY A 633
 None
 0.79A 6eu9D-4otdA:
undetectable		 6eu9D-4otdA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0a E3 UBIQUITIN-PROTEIN
LIGASE RNF31

(Homo sapiens) 		PF09409
(PUB) 		4 VAL A 149
LEU A  56
GLY A 123
GLY A 115
 None
 0.78A 6eu9D-4p0aA:
undetectable		 6eu9D-4p0aA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppr PENICILLIN-BINDING
PROTEIN DACB1

(Mycobacterium
tuberculosis) 		PF00768
(Peptidase_S11) 		4 LEU A 309
GLY A 115
LEU A  74
GLY A  70
 None
 0.71A 6eu9D-4pprA:
undetectable		 6eu9D-4pprA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6k BNR/ASP-BOX REPEAT
PROTEIN

(Bacteroides
caccae) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 LEU A 172
GLY A 223
LEU A 232
GLY A 261
 None
 0.68A 6eu9D-4q6kA:
undetectable		 6eu9D-4q6kA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkr TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Arthrobacter
sp. FB24) 		PF13377
(Peripla_BP_3) 		4 LEU A 178
LEU A 290
GLY A 260
GLY A 249
 None
 0.76A 6eu9D-4rkrA:
undetectable		 6eu9D-4rkrA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rxm POSSIBLE SUGAR ABC
SUPERFAMILY ATP
BINDING CASSETTE
TRANSPORTER, BINDING
PROTEIN

(Mannheimia
haemolytica) 		PF13407
(Peripla_BP_4) 		4 LEU A 232
GLY A 235
LEU A 257
GLY A 241
 None
 0.79A 6eu9D-4rxmA:
undetectable		 6eu9D-4rxmA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzl RESTRICTION
ENDONUCLEASE LPNPI

(Legionella
pneumophila) 		no annotation 4 PHE A  80
LEU A  60
GLY A  84
GLY A  67
 None
 0.77A 6eu9D-4rzlA:
undetectable		 6eu9D-4rzlA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE

(Agrobacterium
tumefaciens) 		PF00701
(DHDPS) 		4 VAL A  99
GLY A 106
LEU A 109
GLY A  86
 None
 0.75A 6eu9D-4ur8A:
undetectable		 6eu9D-4ur8A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4woj ASPARTATE
SEMIALDEHYDE
DEHYDROGENASE

(Francisella
tularensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 VAL A  16
LEU A 321
GLY A 319
GLY A 166
 None
 0.72A 6eu9D-4wojA:
undetectable		 6eu9D-4wojA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgz ANTIZYME INHIBITOR 1
ORNITHINE
DECARBOXYLASE
ANTIZYME 1

(Homo sapiens) 		PF00278
(Orn_DAP_Arg_deC)
PF02100
(ODC_AZ)
PF02784
(Orn_Arg_deC_N) 		4 LEU B 187
LEU A 353
GLY A 355
LEU A 361
 None
 0.75A 6eu9D-4zgzB:
undetectable		 6eu9D-4zgzB:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah4 DNA POLYMERASE III
SUBUNIT BETA

(Mycolicibacterium
smegmatis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 LEU A  31
PHE A  20
LEU A  78
GLY A  42
 None
 0.78A 6eu9D-5ah4A:
undetectable		 6eu9D-5ah4A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ahm INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00478
(IMPDH) 		4 LEU A 334
LEU A 436
GLY A 344
GLY A 353
 None
 0.72A 6eu9D-5ahmA:
undetectable		 6eu9D-5ahmA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4n F-BOX ONLY PROTEIN 2

(Mus musculus) 		PF04300
(FBA) 		4 LEU A 222
LEU A 137
GLY A 133
LEU A 128
 None
 0.79A 6eu9D-5b4nA:
undetectable		 6eu9D-5b4nA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnt ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Pseudomonas
aeruginosa) 		no annotation 4 VAL C  16
LEU C 326
GLY C 324
GLY C 166
 None
 0.75A 6eu9D-5bntC:
undetectable		 6eu9D-5bntC:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by6 THYMIDYLATE SYNTHASE

(Trichinella
spiralis) 		PF00303
(Thymidylat_synt) 		4 VAL A 128
LEU A 112
GLY A  88
GLY A 123
 None
 0.81A 6eu9D-5by6A:
undetectable		 6eu9D-5by6A:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c91 E3 UBIQUITIN-PROTEIN
LIGASE NEDD4

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 529
GLY A 643
LEU A 651
GLY A 779
 None
 0.81A 6eu9D-5c91A:
undetectable		 6eu9D-5c91A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d4k POLYMERIC
IMMUNOGLOBULIN
RECEPTOR

(Homo sapiens) 		PF07686
(V-set) 		4 VAL A 292
LEU A 241
LEU A 326
GLY A 308
 None
 0.80A 6eu9D-5d4kA:
undetectable		 6eu9D-5d4kA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e26 PANTOTHENATE KINASE
2, MITOCHONDRIAL

(Homo sapiens) 		PF03630
(Fumble) 		4 VAL A 517
PHE A 550
GLY A 502
GLY A 544
 None
 0.76A 6eu9D-5e26A:
undetectable		 6eu9D-5e26A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE

(Bacillus
subtilis) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N)
PF07831
(PYNP_C) 		4 LEU A 306
GLY A 262
LEU A 296
GLY A 276
 LEU  A 306 ( 0.6A)
GLY  A 262 ( 0.0A)
LEU  A 296 ( 0.5A)
GLY  A 276 ( 0.0A)
 0.70A 6eu9D-5ep8A:
undetectable		 6eu9D-5ep8A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR

(Homo sapiens) 		PF09240
(IL6Ra-bind) 		4 VAL C 161
LEU C 129
LEU C 195
GLY C 191
 None
 0.76A 6eu9D-5fucC:
undetectable		 6eu9D-5fucC:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gll GLYCOSIDE HYDROLASE
FAMILY 43

(uncultured
bacterium) 		PF04616
(Glyco_hydro_43) 		4 PHE A 332
LEU A  49
GLY A 103
GLY A  65
 None
 0.74A 6eu9D-5gllA:
undetectable		 6eu9D-5gllA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gp4 GLUTAMATE
DECARBOXYLASE

(Lactobacillus
brevis) 		no annotation 4 PHE C 334
LEU C 109
GLY C 251
GLY C 125
 None
None
None
PLP  C 501 (-3.6A)
 0.80A 6eu9D-5gp4C:
undetectable		 6eu9D-5gp4C:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpk E3 UBIQUITIN-PROTEIN
LIGASE NEDD4-LIKE

(Homo sapiens) 		PF00632
(HECT) 		4 PHE A 584
GLY A 698
LEU A 706
GLY A 834
 None
 0.70A 6eu9D-5hpkA:
undetectable		 6eu9D-5hpkA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hz1 PROBABLE LRR
RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE
AT4G26540

(Arabidopsis
thaliana) 		PF13855
(LRR_8) 		4 PHE B 317
GLY B 307
LEU B 285
GLY B 259
 None
 0.68A 6eu9D-5hz1B:
undetectable		 6eu9D-5hz1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jcn OS09G0567300 PROTEIN

(Oryza sativa) 		PF07992
(Pyr_redox_2) 		4 LEU A 345
LEU A 429
GLY A 383
GLY A 361
 None
 0.81A 6eu9D-5jcnA:
undetectable		 6eu9D-5jcnA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liv CYTOCHROME P450
CYP260A1,CYTOCHROME
P450 CYP260A1

(Sorangium
cellulosum) 		PF00067
(p450) 		4 VAL A 432
PHE A 327
LEU A 330
GLY A 279
 None
None
None
GOL  A 502 ( 3.2A)
 0.79A 6eu9D-5livA:
2.1		 6eu9D-5livA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg8 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
6

(Schizosaccharomyces
pombe) 		no annotation 4 PHE B 631
LEU B 626
GLY B 645
GLY B 573
 None
 0.75A 6eu9D-5mg8B:
undetectable		 6eu9D-5mg8B:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu7 COATOMER SUBUNIT
BETA

(Chaetomium
thermophilum) 		PF01602
(Adaptin_N) 		4 VAL A 325
LEU A 356
LEU A 318
GLY A 282
 None
 0.74A 6eu9D-5mu7A:
undetectable		 6eu9D-5mu7A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oaf RUVB-LIKE 1

(Homo sapiens) 		no annotation 4 LEU A 355
GLY A 349
LEU A 307
GLY A  98
 None
 0.65A 6eu9D-5oafA:
undetectable		 6eu9D-5oafA:
26.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue7 PHOSPHOMANNOMUTASE

(Candida
albicans) 		PF03332
(PMM) 		4 LEU A  12
LEU A  77
GLY A  50
GLY A  46
 None
 0.78A 6eu9D-5ue7A:
undetectable		 6eu9D-5ue7A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w16 GLUTAMATE RACEMASE

(Thermus
thermophilus) 		no annotation 4 VAL A  97
LEU A 113
GLY A  17
GLY A 115
 None
 0.70A 6eu9D-5w16A:
undetectable		 6eu9D-5w16A:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bac ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Neisseria
gonorrhoeae) 		no annotation 4 VAL A  15
LEU A 326
GLY A 324
GLY A 166
 None
 0.69A 6eu9D-6bacA:
undetectable		 6eu9D-6bacA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE

(Klebsiella
pneumoniae) 		no annotation 4 PHE A  88
LEU A  59
GLY A 173
LEU A 199
 None
 0.77A 6eu9D-6blgA:
undetectable		 6eu9D-6blgA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MBH SUBUNIT
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT C
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT D

(Pyrococcus
furiosus) 		no annotation 4 LEU H 118
GLY G  86
LEU G  92
GLY E  85
 None
 0.76A 6eu9D-6cfwH:
undetectable		 6eu9D-6cfwH:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fx0 RETINOIC ACID
RECEPTOR GAMMA

(Homo sapiens) 		no annotation 4 LEU A 268
LEU A 294
LEU A 307
GLY A 393
 E9T  A 501 (-4.9A)
None
None
E9T  A 501 (-3.7A)
 0.46A 6eu9D-6fx0A:
28.6		 6eu9D-6fx0A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fx0 RETINOIC ACID
RECEPTOR GAMMA

(Homo sapiens) 		no annotation 4 LEU A 268
PHE A 288
LEU A 294
LEU A 307
 E9T  A 501 (-4.9A)
E9T  A 501 (-4.7A)
None
None
 0.63A 6eu9D-6fx0A:
28.6		 6eu9D-6fx0A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gh2 LAMINARIBIOSE
PHOSPHORYLASE

(Paenibacillus
sp. YM1) 		no annotation 4 PHE A 132
GLY A 310
LEU A 307
GLY A 217
 None
 0.72A 6eu9D-6gh2A:
undetectable		 6eu9D-6gh2A:
23.16