SIMILAR PATTERNS OF AMINO ACIDS FOR 6EQP_A_BUWA601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		6 TRP A  86
GLY A 122
SER A 203
TRP A 236
PHE A 338
TYR A 341
 None
 0.54A 6eqpA-1b41A:
57.2		 6eqpA-1b41A:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bev BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4

(Enterovirus E) 		PF00073
(Rhv) 		4 GLY 2 120
GLN 2 119
THR 3 120
TRP 2  71
 None
 1.16A 6eqpA-1bev2:
undetectable		 6eqpA-1bev2:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bxt PROTEIN
(STREPTOCOCCAL
SUPERANTIGEN)

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 GLY A 111
GLN A 154
THR A 152
PHE A  51
 None
 1.16A 6eqpA-1bxtA:
undetectable		 6eqpA-1bxtA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 GLY A 121
SER A 203
PHE A 338
TYR A 341
 None
 1.02A 6eqpA-1c2oA:
56.6		 6eqpA-1c2oA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		6 TRP A  86
GLY A 122
SER A 203
TRP A 236
PHE A 338
TYR A 341
 None
 0.43A 6eqpA-1c2oA:
56.6		 6eqpA-1c2oA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3d [NIFE] HYDROGENASE
LARGE SUBUNIT

(Desulfovibrio
desulfuricans) 		PF00374
(NiFeSe_Hases) 		4 GLY B 497
THR B 493
SER B  43
TYR B 336
 None
 1.14A 6eqpA-1e3dB:
undetectable		 6eqpA-1e3dB:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanopyrus
kandleri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		4 GLY B 131
GLN B 134
SER B 178
TYR B 165
 None
 1.14A 6eqpA-1e6vB:
undetectable		 6eqpA-1e6vB:
12.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		4 GLY A 118
SER A 200
PHE A 331
TYR A 334
 SAF  A1998 ( 3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.7A)
None
 0.66A 6eqpA-1gqrA:
61.0		 6eqpA-1gqrA:
46.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gqr ACETYLCHOLINESTERASE

(Tetronarce
californica) 		PF00135
(COesterase) 		6 TRP A  84
GLY A 119
SER A 200
TRP A 233
PHE A 331
TYR A 334
 SAF  A1998 (-3.8A)
EMM  A1999 (-3.5A)
EMM  A1999 ( 1.4A)
EMM  A1999 (-4.0A)
EMM  A1999 (-4.7A)
None
 0.59A 6eqpA-1gqrA:
61.0		 6eqpA-1gqrA:
46.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ijt FIBROBLAST GROWTH
FACTOR 4

(Homo sapiens) 		PF00167
(FGF) 		4 GLY A 105
GLN A  97
PHE A 202
TYR A  87
 None
 1.15A 6eqpA-1ijtA:
undetectable		 6eqpA-1ijtA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m4x PBCV-1 VIRUS CAPSID

(Paramecium
bursaria
Chlorella virus
1) 		PF04451
(Capsid_NCLDV)
PF16903
(Capsid_N) 		4 GLY A 185
GLN A 184
THR A  85
PHE A  52
 None
 1.03A 6eqpA-1m4xA:
undetectable		 6eqpA-1m4xA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mza PRO-GRANZYME K

(Homo sapiens) 		PF00089
(Trypsin) 		4 GLY A  43
THR A  54
TRP A 141
TYR A  35
 None
 0.97A 6eqpA-1mzaA:
undetectable		 6eqpA-1mzaA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n3y INTEGRIN ALPHA-X

(Homo sapiens) 		PF00092
(VWA) 		4 GLY A 139
GLN A 173
SER A 142
PHE A 300
 None
 0.92A 6eqpA-1n3yA:
3.2		 6eqpA-1n3yA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nzy 4-CHLOROBENZOYL
COENZYME A
DEHALOGENASE

(Pseudomonas sp.
CBS3) 		PF00378
(ECH_1) 		4 GLY B 117
THR B 146
SER B 122
PHE B  60
 None
BCA  B 272 (-4.3A)
None
None
 1.15A 6eqpA-1nzyB:
2.0		 6eqpA-1nzyB:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pkq (8-18C5) CHIMERIC
FAB, HEAVY CHAIN

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLY B  10
THR B 108
PHE B 146
TYR B 176
 None
 0.94A 6eqpA-1pkqB:
undetectable		 6eqpA-1pkqB:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qon ACETYLCHOLINESTERASE

(Drosophila
melanogaster) 		PF00135
(COesterase) 		4 GLY A 150
SER A 238
PHE A 371
TYR A 374
 I40  A 997 (-3.9A)
SO4  A 593 (-1.9A)
I40  A 997 (-4.9A)
I40  A 997 ( 3.9A)
 0.77A 6eqpA-1qonA:
59.8		 6eqpA-1qonA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qon ACETYLCHOLINESTERASE

(Drosophila
melanogaster) 		PF00135
(COesterase) 		7 TRP A  83
GLY A 151
THR A 154
SER A 238
TRP A 271
PHE A 371
TYR A 374
 I40  A 997 (-3.2A)
SO4  A 593 (-3.4A)
None
SO4  A 593 (-1.9A)
SO4  A 593 (-4.4A)
I40  A 997 (-4.9A)
I40  A 997 ( 3.9A)
 0.65A 6eqpA-1qonA:
59.8		 6eqpA-1qonA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu9 YJGF PROTEIN

(Escherichia
coli) 		PF01042
(Ribonuc_L-PSP) 		4 GLN A  32
THR A  29
PHE A  94
TYR A  91
 None
 0.86A 6eqpA-1qu9A:
undetectable		 6eqpA-1qu9A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5r LUKS-PV

(Staphylococcus
phage PVL) 		PF07968
(Leukocidin) 		4 GLY A 157
SER A 144
PHE A 206
TYR A 230
 None
 1.15A 6eqpA-1t5rA:
undetectable		 6eqpA-1t5rA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t77 LIPOPOLYSACCHARIDE-R
ESPONSIVE AND
BEIGE-LIKE ANCHOR
PROTEIN

(Homo sapiens) 		PF02138
(Beach)
PF14844
(PH_BEACH) 		4 GLY A2475
GLN A2476
THR A2448
PHE A2310
 None
 1.14A 6eqpA-1t77A:
undetectable		 6eqpA-1t77A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx0 HYPOTHETICAL PROTEIN
YSNE

(Bacillus
subtilis) 		PF00583
(Acetyltransf_1) 		4 GLY A  86
THR A  78
PHE A 127
TYR A 124
 None
 0.80A 6eqpA-1yx0A:
undetectable		 6eqpA-1yx0A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cas CANINE PARVOVIRUS
EMPTY CAPSID (STRAIN
D) VIRAL PROTEIN 2

(Carnivore
protoparvovirus
1) 		PF00740
(Parvo_coat) 		4 GLY A 381
GLN A 386
SER A 192
PHE A 197
 None
 1.17A 6eqpA-2casA:
undetectable		 6eqpA-2casA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gou OXIDOREDUCTASE,
FMN-BINDING

(Shewanella
oneidensis) 		PF00724
(Oxidored_FMN) 		4 GLY A  58
SER A  56
TRP A  83
TYR A 163
 FMN  A4401 (-3.7A)
None
None
None
 1.07A 6eqpA-2gouA:
2.2		 6eqpA-2gouA:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gtp REGULATOR OF
G-PROTEIN SIGNALING
1

(Homo sapiens) 		PF00615
(RGS) 		4 GLY C  82
GLN C  83
PHE C 177
TYR C 174
 None
 0.80A 6eqpA-2gtpC:
undetectable		 6eqpA-2gtpC:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gy7 ANGIOPOIETIN-2

(Homo sapiens) 		PF00147
(Fibrinogen_C) 		4 TRP A 339
GLY A 443
GLN A 336
PHE A 346
 None
 0.91A 6eqpA-2gy7A:
undetectable		 6eqpA-2gy7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0r NICOTINAMIDASE

(Saccharomyces
cerevisiae) 		PF00857
(Isochorismatase) 		4 GLY A 101
GLN A 103
THR A  99
SER A  19
 None
 1.11A 6eqpA-2h0rA:
undetectable		 6eqpA-2h0rA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbw 2,6-DIHYDROXY-PSEUDO
-OXYNICOTINE
HYDROLASE

(Paenarthrobacter
nicotinovorans) 		PF06500
(DUF1100) 		4 GLY A 146
GLN A 176
THR A 150
TYR A 261
 None
 1.16A 6eqpA-2jbwA:
15.2		 6eqpA-2jbwA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n52 SERINE PROTEASE
INHIBITOR KAZAL-TYPE
6

(Homo sapiens) 		PF00050
(Kazal_1) 		4 GLY A  47
GLN A  11
PHE A  38
TYR A  32
 None
 1.04A 6eqpA-2n52A:
undetectable		 6eqpA-2n52A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 GLY A 753
GLN A 754
SER A 703
PHE A 724
 None
 1.17A 6eqpA-2olsA:
undetectable		 6eqpA-2olsA:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2psy KALLIKREIN-5

(Homo sapiens) 		PF00089
(Trypsin) 		4 TRP A  51
GLY A  85
GLN A  84
SER A  88
 None
 1.11A 6eqpA-2psyA:
undetectable		 6eqpA-2psyA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8n LACTOSE PERMEASE

(Escherichia
coli) 		PF01306
(LacY_symp) 		4 GLY A 257
GLN A 256
THR A 253
PHE A 162
 None
 1.08A 6eqpA-2v8nA:
undetectable		 6eqpA-2v8nA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zy2 L-ASPARTATE
4-CARBOXYLYASE

(Pseudomonas sp.
ATCC 19121) 		PF00155
(Aminotran_1_2) 		4 GLY A 318
THR A 320
PHE A 292
TYR A 289
 None
None
None
PLP  A 900 (-4.0A)
 1.03A 6eqpA-2zy2A:
2.4		 6eqpA-2zy2A:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enk UDP-GLUCOSE
4-EPIMERASE

(Burkholderia
pseudomallei) 		PF16363
(GDP_Man_Dehyd) 		4 GLY A 153
GLN A 154
THR A 155
SER A 128
 None
None
None
UPG  A 342 (-2.7A)
 1.00A 6eqpA-3enkA:
3.2		 6eqpA-3enkA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evc RNA-DIRECTED RNA
POLYMERASE NS5

(Yellow fever
virus) 		PF01728
(FtsJ) 		4 THR A 236
SER A 212
PHE A  65
TYR A  70
 None
 1.16A 6eqpA-3evcA:
undetectable		 6eqpA-3evcA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f6t ASPARTATE
AMINOTRANSFERASE

(Lactobacillus
acidophilus) 		PF00155
(Aminotran_1_2) 		4 GLY A 315
THR A 317
PHE A 289
TYR A 286
 LLP  A 312 ( 4.6A)
None
LLP  A 312 ( 4.9A)
LLP  A 312 ( 4.6A)
 0.92A 6eqpA-3f6tA:
undetectable		 6eqpA-3f6tA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdd L-ASPARTATE-BETA-DEC
ARBOXYLASE

(Comamonas
testosteroni) 		PF00155
(Aminotran_1_2) 		4 GLY A 318
THR A 320
PHE A 292
TYR A 289
 None
None
None
PLP  A 534 (-4.6A)
 0.98A 6eqpA-3fddA:
undetectable		 6eqpA-3fddA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdu PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE

(Acinetobacter
baumannii) 		PF00378
(ECH_1) 		4 GLY A 151
GLN A 126
THR A 122
TYR A  40
 None
 1.01A 6eqpA-3fduA:
undetectable		 6eqpA-3fduA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd9 LAMINARIPENTAOSE-PRO
DUCING
BETA-1,3-GULUASE
(LPHASE)

(Streptomyces
matensis) 		PF16483
(Glyco_hydro_64) 		4 GLY A 372
GLN A 168
THR A 167
TYR A 232
 None
None
BGC  A   3 (-3.3A)
None
 1.12A 6eqpA-3gd9A:
undetectable		 6eqpA-3gd9A:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT

(Corynebacterium
diphtheriae) 		no annotation 4 GLY A 416
GLN A 358
SER A 212
PHE A 442
 None
 1.16A 6eqpA-3hr6A:
undetectable		 6eqpA-3hr6A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ive NUCLEOTIDASE

(Escherichia
coli) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		4 GLY A 473
THR A 475
SER A 419
PHE A 170
 None
 1.10A 6eqpA-3iveA:
undetectable		 6eqpA-3iveA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9q SHEATH

(Pseudomonas
aeruginosa) 		PF04984
(Phage_sheath_1)
PF17482
(Phage_sheath_1C) 		4 GLY A 100
GLN A 112
THR A 109
SER A  96
 None
 1.17A 6eqpA-3j9qA:
2.9		 6eqpA-3j9qA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m3i PUTATIVE
UNCHARACTERIZED
PROTEIN

(Leishmania
major) 		PF06172
(Cupin_5) 		4 GLY A 173
THR A  53
SER A  72
TYR A 176
 None
 1.16A 6eqpA-3m3iA:
undetectable		 6eqpA-3m3iA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rty PERIOD CIRCADIAN
PROTEIN

(Drosophila
melanogaster) 		PF00989
(PAS)
PF14598
(PAS_11) 		4 GLY A 447
GLN A 448
THR A 449
SER A 477
 None
 1.17A 6eqpA-3rtyA:
undetectable		 6eqpA-3rtyA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t20 CIS-ACONITATE PORIN
OPDH

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 GLY A   2
GLN A  48
THR A  47
SER A   7
 None
 1.04A 6eqpA-3t20A:
undetectable		 6eqpA-3t20A:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		4 GLY A1294
THR A1593
PHE A1447
TYR A1437
 None
 1.10A 6eqpA-4bedA:
undetectable		 6eqpA-4bedA:
4.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
ALPHA

(Methanothermobacter
marburgensis) 		PF00374
(NiFeSe_Hases) 		4 GLY A 275
GLN A 279
PHE A 365
TYR A 369
 None
 1.01A 6eqpA-4ci0A:
undetectable		 6eqpA-4ci0A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e7w GLYCOGEN SYNTHASE
KINASE 3

(Ustilago maydis) 		PF00069
(Pkinase) 		4 GLY A 234
GLN A 233
SER A 124
TYR A 202
 None
 1.13A 6eqpA-4e7wA:
undetectable		 6eqpA-4e7wA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ecn LEUCINE-RICH REPEAT
PROTEIN

(Bacteroides
thetaiotaomicron) 		PF14660
(DUF4458) 		4 GLY A 383
THR A 462
SER A 357
PHE A 394
 None
 1.00A 6eqpA-4ecnA:
undetectable		 6eqpA-4ecnA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fl0 AMINOTRANSFERASE
ALD1

(Arabidopsis
thaliana) 		PF00155
(Aminotran_1_2) 		4 GLY A 287
THR A 289
PHE A 257
TYR A 254
 None
None
None
PLP  A 501 (-4.5A)
 1.06A 6eqpA-4fl0A:
undetectable		 6eqpA-4fl0A:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdj NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 GLY A 351
GLN A 350
SER A 363
TYR A 281
 None
 1.17A 6eqpA-4gdjA:
undetectable		 6eqpA-4gdjA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdj NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 GLY A 351
GLN A 350
THR A 279
PHE A 374
 None
 1.10A 6eqpA-4gdjA:
undetectable		 6eqpA-4gdjA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ged ASCORBATE PEROXIDASE

(Leishmania
major) 		PF00141
(peroxidase) 		4 GLY A 145
THR A 292
SER A 119
TYR A 129
 None
 1.14A 6eqpA-4gedA:
undetectable		 6eqpA-4gedA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gl8 OLIGOPEPTIDE ABC
TRANSPORTER OPPAIV

(Borreliella
burgdorferi) 		PF00496
(SBP_bac_5) 		4 GLY A  56
THR A  52
SER A  59
TYR A 503
 None
 1.17A 6eqpA-4gl8A:
undetectable		 6eqpA-4gl8A:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iel GLUTATHIONE
S-TRANSFERASE,
N-TERMINAL DOMAIN
PROTEIN

(Burkholderia
ambifaria) 		PF13417
(GST_N_3) 		4 TRP A 108
GLY A 134
GLN A 130
PHE A 177
 None
 0.98A 6eqpA-4ielA:
undetectable		 6eqpA-4ielA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3y NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 GLY A 351
GLN A 350
THR A 279
PHE A 374
 None
 1.12A 6eqpA-4k3yA:
undetectable		 6eqpA-4k3yA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kav YHBX/YHJW/YIJP/YJDB
FAMILY PROTEIN

(Neisseria
meningitidis) 		PF00884
(Sulfatase) 		4 GLY A 454
GLN A 476
THR A 477
SER A 451
 None
 1.15A 6eqpA-4kavA:
undetectable		 6eqpA-4kavA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kws D-MANNONATE
DEHYDRATASE

(Chromohalobacter
salexigens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLY A 162
GLN A 151
THR A 126
TRP A 405
 None
 1.16A 6eqpA-4kwsA:
2.9		 6eqpA-4kwsA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l08 HYDROLASE,
ISOCHORISMATASE
FAMILY

(Pseudomonas
putida) 		no annotation 4 GLY B  32
THR B  40
SER B  30
TYR B  72
 None
 1.12A 6eqpA-4l08B:
undetectable		 6eqpA-4l08B:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7t NANU SIALIC ACID
BINDING PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 GLY A 314
GLN A 293
THR A 297
PHE A 362
 None
 1.10A 6eqpA-4l7tA:
undetectable		 6eqpA-4l7tA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN ALPHA-X

(Homo sapiens) 		PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 GLY A 352
GLN A 334
SER A 357
PHE A 371
 None
None
NAG  A1105 (-3.2A)
NAG  A1105 (-4.7A)
 0.93A 6eqpA-4nenA:
undetectable		 6eqpA-4nenA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nre ARACHIDONATE
15-LIPOXYGENASE B

(Homo sapiens) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 GLY A 432
GLN A 308
THR A 300
SER A 366
 None
 1.16A 6eqpA-4nreA:
undetectable		 6eqpA-4nreA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4om9 SERINE PROTEASE PET

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 GLY A 792
GLN A 791
SER A 814
PHE A 828
 None
 1.15A 6eqpA-4om9A:
undetectable		 6eqpA-4om9A:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfb C4-DICARBOXYLATE-BIN
DING PROTEIN

(Fusobacterium
nucleatum) 		PF03480
(DctP) 		4 GLN A  38
THR A  39
SER A 209
PHE A 112
 None
 0.98A 6eqpA-4pfbA:
undetectable		 6eqpA-4pfbA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q3k MGS-M1

(unidentified) 		PF00326
(Peptidase_S9)
PF07859
(Abhydrolase_3) 		4 GLY A  43
GLN A  45
SER A 113
TRP A 147
 F  A 302 (-3.4A)
None
F  A 302 (-2.5A)
PGE  A 303 ( 4.6A)
 0.97A 6eqpA-4q3kA:
18.6		 6eqpA-4q3kA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4y COXSACKIEVIRUS
CAPSID PROTEIN VP1
COXSACKIEVIRUS
CAPSID PROTEIN VP2

(Enterovirus C) 		PF00073
(Rhv) 		4 GLY 1  50
GLN 2 195
SER 1  52
TYR 2  35
 None
 0.84A 6eqpA-4q4y1:
undetectable		 6eqpA-4q4y1:
11.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qww ACETYLCHOLINESTERASE

(Bungarus
fasciatus) 		PF00135
(COesterase) 		4 GLY A 118
SER A 200
PHE A 331
TYR A 334
 None
 1.04A 6eqpA-4qwwA:
61.4		 6eqpA-4qwwA:
41.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qww ACETYLCHOLINESTERASE

(Bungarus
fasciatus) 		PF00135
(COesterase) 		6 TRP A  84
GLY A 119
SER A 200
TRP A 233
PHE A 331
TYR A 334
 None
 0.48A 6eqpA-4qwwA:
61.4		 6eqpA-4qwwA:
41.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rbn SUCROSE
SYNTHASE:GLYCOSYL
TRANSFERASES GROUP 1

(Nitrosomonas
europaea) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		4 GLN A  12
THR A   9
SER A  52
TYR A  25
 None
 1.11A 6eqpA-4rbnA:
3.7		 6eqpA-4rbnA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru1 MONOSACCHARIDE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT2 FAMILY

(Acidothermus
cellulolyticus) 		PF13407
(Peripla_BP_4) 		4 GLY A 193
GLN A 161
THR A 197
PHE A 259
 None
 0.96A 6eqpA-4ru1A:
2.8		 6eqpA-4ru1A:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		4 GLY A 734
GLN A 735
SER A 732
PHE A 768
 None
 1.02A 6eqpA-4uwaA:
undetectable		 6eqpA-4uwaA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ux8 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET

(Homo sapiens) 		PF00028
(Cadherin) 		4 TRP A 324
GLY A 344
THR A 328
PHE A 285
 None
 1.00A 6eqpA-4ux8A:
undetectable		 6eqpA-4ux8A:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xi2 TYROSINE-PROTEIN
KINASE BTK

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 GLY A 389
GLN A 459
THR A 387
SER A 394
 None
 0.86A 6eqpA-4xi2A:
undetectable		 6eqpA-4xi2A:
13.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xii CHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		5 GLY A 116
THR A 120
SER A 198
PHE A 329
TYR A 332
 40V  A1001 (-3.2A)
40V  A1001 ( 4.5A)
40V  A1001 (-3.1A)
40V  A1001 (-4.0A)
40V  A1001 (-3.8A)
 1.19A 6eqpA-4xiiA:
71.2		 6eqpA-4xiiA:
98.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xii CHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		8 TRP A  82
GLY A 117
GLN A 119
THR A 120
SER A 198
TRP A 231
PHE A 329
TYR A 332
 40V  A1001 (-3.3A)
40V  A1001 (-3.4A)
None
40V  A1001 ( 4.5A)
40V  A1001 (-3.1A)
40V  A1001 (-3.4A)
40V  A1001 (-4.0A)
40V  A1001 (-3.8A)
 0.40A 6eqpA-4xiiA:
71.2		 6eqpA-4xiiA:
98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y25 POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
EXPORT PROTEIN

(Escherichia
coli) 		no annotation 4 GLY A 747
GLN A 763
THR A 762
PHE A 744
 None
 0.99A 6eqpA-4y25A:
undetectable		 6eqpA-4y25A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yn1 FUSOLIN

(Anomala cuprea
entomopoxvirus) 		PF03067
(LPMO_10) 		4 GLY A 224
GLN A 216
PHE A 138
TYR A 196
 None
 0.86A 6eqpA-4yn1A:
undetectable		 6eqpA-4yn1A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yn2 FUSOLIN

(unidentified
entomopoxvirus) 		PF03067
(LPMO_10) 		4 GLY A 221
GLN A 213
PHE A 136
TYR A 193
 None
 0.80A 6eqpA-4yn2A:
undetectable		 6eqpA-4yn2A:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yn5 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE

(Bacillus sp.
JAMB750) 		PF02156
(Glyco_hydro_26) 		4 GLY A  68
GLN A 361
PHE A 396
TYR A 341
 None
 1.16A 6eqpA-4yn5A:
undetectable		 6eqpA-4yn5A:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a22 VESICULAR STOMATITIS
VIRUS L POLYMERASE

(Vesicular
stomatitis
virus) 		PF00946
(Mononeg_RNA_pol)
PF14314
(Methyltrans_Mon)
PF14318
(Mononeg_mRNAcap) 		4 GLY A1704
THR A1253
SER A1451
PHE A1387
 None
 1.14A 6eqpA-5a22A:
undetectable		 6eqpA-5a22A:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7m BETA-XYLOSIDASE

(Trichoderma
reesei) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 GLY A 325
GLN A 326
THR A 327
SER A 290
 None
 1.14A 6eqpA-5a7mA:
undetectable		 6eqpA-5a7mA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eo7 PREDICTED PROTEIN

(Aspergillus
oryzae) 		PF07938
(Fungal_lectin) 		4 GLY A   5
GLN A   7
THR A   3
PHE A  28
 None
 1.11A 6eqpA-5eo7A:
undetectable		 6eqpA-5eo7A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqi SOLUTE CARRIER
FAMILY 2,
FACILITATED GLUCOSE
TRANSPORTER MEMBER 1

(Homo sapiens) 		PF00083
(Sugar_tr) 		4 TRP A 388
GLY A 138
SER A  80
PHE A  26
 5RH  A 501 (-3.1A)
None
5RH  A 501 (-2.7A)
None
 1.04A 6eqpA-5eqiA:
undetectable		 6eqpA-5eqiA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ezo C12 FAB

(Plasmodium
falciparum) 		no annotation 4 GLY A 329
GLN A 281
THR A 331
SER A 345
 None
 1.05A 6eqpA-5ezoA:
undetectable		 6eqpA-5ezoA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq6 SUSC/RAGA FAMILY
TONB-LINKED OUTER
MEMBRANE PROTEIN

(Bacteroides
thetaiotaomicron) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 GLY B 563
THR B 543
TRP B 591
TYR B  42
 None
 1.07A 6eqpA-5fq6B:
undetectable		 6eqpA-5fq6B:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsa CYP51 VARIANT1

(Candida
albicans) 		PF00067
(p450) 		4 GLY A  65
GLN A  66
PHE A  72
TYR A  69
 X2N  A 590 ( 4.0A)
None
None
None
 1.10A 6eqpA-5fsaA:
undetectable		 6eqpA-5fsaA:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fxe EUGENOL OXIDASE

(Rhodococcus
jostii) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		4 GLY A 231
GLN A 178
THR A 179
TYR A 171
 None
GOL  A1529 (-3.3A)
None
None
 1.16A 6eqpA-5fxeA:
undetectable		 6eqpA-5fxeA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyn PUUMALA VIRUS GN
GLYCOPROTEIN

(Puumala
orthohantavirus) 		PF01567
(Hanta_G1) 		4 GLY A 351
GLN A 143
THR A  86
SER A 334
 None
NAG  A1382 ( 4.7A)
None
None
 1.03A 6eqpA-5fynA:
undetectable		 6eqpA-5fynA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsg PUTATIVE ABC
TRANSPORTER,
NUCLEOTIDE
BINDING/ATPASE
PROTEIN

(Klebsiella
pneumoniae) 		PF13407
(Peripla_BP_4) 		4 GLY A 157
GLN A 152
PHE A 147
TYR A 146
 None
 1.03A 6eqpA-5hsgA:
undetectable		 6eqpA-5hsgA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0u CAPSID PROTEIN VP1
CAPSID PROTEIN VP2

(Rhinovirus C) 		PF00073
(Rhv) 		4 GLY A  43
GLN C 192
SER A  45
TYR C  35
 None
 0.95A 6eqpA-5k0uA:
undetectable		 6eqpA-5k0uA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN

(Desulfovibrio
alaskensis) 		PF12849
(PBP_like_2) 		4 GLY A 119
GLN A 148
THR A 149
SER A 122
 None
 0.86A 6eqpA-5my5A:
undetectable		 6eqpA-5my5A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz9 -

(-) 		no annotation 4 GLN A 380
THR A 379
PHE A 397
TYR A 322
 None
 1.00A 6eqpA-5mz9A:
undetectable		 6eqpA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npx POLYPROTEIN

(Broad bean
stain virus) 		no annotation 4 GLY L 219
GLN L 311
THR L 310
TYR L 236
 None
 1.12A 6eqpA-5npxL:
undetectable		 6eqpA-5npxL:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8m ANTIBODY 3BNC117,
HEAVY CHAIN

(Homo sapiens) 		PF07686
(V-set) 		4 GLY H  44
GLN H  43
PHE H  91
TYR H  90
 None
 1.08A 6eqpA-5v8mH:
undetectable		 6eqpA-5v8mH:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydj ACETYLCHOLINESTERASE

(Anopheles
gambiae) 		no annotation 5 TRP A 245
GLY A 280
TRP A 393
PHE A 490
TYR A 493
 SEB  A 360 ( 4.2A)
SEB  A 360 ( 3.0A)
None
None
None
 0.62A 6eqpA-5ydjA:
undetectable		 6eqpA-5ydjA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yfb DIPEPTIDYL PEPTIDASE
3

(Armillaria
tabescens) 		no annotation 4 GLN A 439
SER A 403
PHE A 521
TYR A 523
 None
 1.11A 6eqpA-5yfbA:
undetectable		 6eqpA-5yfbA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6arx ACETYLCHOLINESTERASE

(Anopheles
gambiae) 		no annotation 4 GLY A 279
SER A 360
PHE A 490
TYR A 493
 None
 0.87A 6eqpA-6arxA:
undetectable		 6eqpA-6arxA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6arx ACETYLCHOLINESTERASE

(Anopheles
gambiae) 		no annotation 5 TRP A 245
SER A 360
TRP A 393
PHE A 490
TYR A 493
 None
 0.61A 6eqpA-6arxA:
undetectable		 6eqpA-6arxA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6au8 GOLGI TO ER TRAFFIC
PROTEIN 4 HOMOLOG

(Homo sapiens) 		no annotation 4 GLY A 229
TRP A 241
PHE A 216
TYR A 219
 None
 1.05A 6eqpA-6au8A:
undetectable		 6eqpA-6au8A:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ayi HTH-TYPE
TRANSCRIPTIONAL
REGULATOR UIDR

(Escherichia
coli) 		no annotation 4 THR A 163
SER A 156
PHE A  83
TYR A  86
 C3G  A 201 (-3.2A)
None
None
None
 1.12A 6eqpA-6ayiA:
undetectable		 6eqpA-6ayiA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10

(Homo sapiens) 		no annotation 4 GLN B  88
SER B  95
PHE B 128
TYR B 122
 None
 1.15A 6eqpA-6c9mB:
undetectable		 6eqpA-6c9mB:
15.85