SIMILAR PATTERNS OF AMINO ACIDS FOR 6ECT_A_SAMA1300_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1akc | ASPARTATEAMINOTRANSFERASE (Gallus gallus) |
PF00155(Aminotran_1_2) | 5 | GLY A 385GLY A 364ILE A 387VAL A 370LEU A 373 | None | 0.93A | 6ectA-1akcA:undetectable | 6ectA-1akcA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b25 | PROTEIN(FORMALDEHYDEFERREDOXINOXIDOREDUCTASE) (Pyrococcusfuriosus) |
PF01314(AFOR_C)PF02730(AFOR_N) | 5 | GLY A 314GLY A 318GLU A 324VAL A 325LEU A 328 | None | 0.81A | 6ectA-1b25A:undetectable | 6ectA-1b25A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b5t | PROTEIN(METHYLENETETRAHYDROFOLATE REDUCTASE) (Escherichiacoli) |
PF02219(MTHFR) | 5 | GLY A 61SER A 72PHE A 30GLU A 28VAL A 58 | NoneNoneNoneFAD A 395 ( 4.3A)None | 0.94A | 6ectA-1b5tA:undetectable | 6ectA-1b5tA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwu | ENOYL ACP REDUCTASE (Brassica napus) |
PF13561(adh_short_C2) | 5 | LEU A 137GLY A 25VAL A 134LEU A 133ILE A 132 | NAD A 501 (-3.9A)NAD A 501 (-3.5A)NoneNoneNone | 0.98A | 6ectA-1cwuA:3.5 | 6ectA-1cwuA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0c | SULFURTRANSFERASE (Azotobactervinelandii) |
PF00581(Rhodanese) | 5 | GLY A 91GLY A 116ASP A 89ILE A 207LEU A 241 | NoneNone MG A 378 ( 4.7A)NoneNone | 1.04A | 6ectA-1e0cA:undetectable | 6ectA-1e0cA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fqk | REGULATOR OFG-PROTEIN SIGNALING9 (Bos taurus) |
PF00615(RGS) | 5 | GLY B 327GLY B 323ILE B 363LEU B 353ILE B 350 | None | 0.92A | 6ectA-1fqkB:undetectable | 6ectA-1fqkB:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k8q | TRIACYLGLYCEROLLIPASE, GASTRIC (Canis lupus) |
PF00561(Abhydrolase_1) | 5 | ASN A 73LEU A 179GLY A 155GLY A 151SER A 99 | BOG A1006 ( 4.5A)NoneNoneNoneNone | 1.06A | 6ectA-1k8qA:undetectable | 6ectA-1k8qA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1knr | L-ASPARTATE OXIDASE (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | GLY A 222GLY A 224VAL A 496LEU A 499ILE A 500 | None | 0.92A | 6ectA-1knrA:2.2 | 6ectA-1knrA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,GAMMA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 5 | LEU E 464SER E 234VAL E 293LEU E 296ILE E 297 | None | 1.01A | 6ectA-1oedE:undetectable | 6ectA-1oedE:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogy | PERIPLASMIC NITRATEREDUCTASE (Rhodobactersphaeroides) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | GLY A 275ASP A 781ILE A 786SER A 155GLU A 437 | None | 0.93A | 6ectA-1ogyA:2.5 | 6ectA-1ogyA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5a | EP-CADHERIN (Mus musculus) |
PF00028(Cadherin) | 5 | ASP A 111GLU A 204VAL A 191LEU A 151ILE A 150 | None | 0.00A | 6ectA-1q5aA:undetectable | 6ectA-1q5aA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qs8 | PLASMEPSIN (Plasmodiumvivax) |
PF00026(Asp) | 6 | LEU A 126GLY A 127ASP A 214ILE A 136LEU A 40ILE A 103 | None | 1.26A | 6ectA-1qs8A:undetectable | 6ectA-1qs8A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8n | KUNITZ TRYPSININHIBITOR (Delonix regia) |
PF00197(Kunitz_legume) | 5 | GLY A 58ILE A 48GLU A 19VAL A 61ILE A 81 | None | 0.87A | 6ectA-1r8nA:undetectable | 6ectA-1r8nA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rhi | HUMAN RHINOVIRUS 3COAT PROTEIN (Rhinovirus B) |
PF00073(Rhv) | 6 | LEU 3 208GLY 3 119ILE 3 155SER 3 123VAL 3 205LEU 3 71 | None | 1.32A | 6ectA-1rhi3:undetectable | 6ectA-1rhi3:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ri3 | MRNA CAPPING ENZYME (Encephalitozooncuniculi) |
PF03291(Pox_MCEL) | 5 | GLY A 72GLY A 74ASP A 78ILE A 95SER A 123 | SAH A 299 (-3.3A)SAH A 299 (-3.5A)SAH A 299 (-4.0A)SAH A 299 (-3.8A)SAH A 299 (-3.1A) | 0.50A | 6ectA-1ri3A:15.7 | 6ectA-1ri3A:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u83 | PHOSPHOSULFOLACTATESYNTHASE (Bacillussubtilis) |
PF02679(ComA) | 5 | ASN A 229LEU A 133GLY A 77ILE A 24PHE A 81 | GOL A1110 (-2.9A)NonePO4 A1000 (-3.3A)GOL A1110 (-4.3A)None | 1.06A | 6ectA-1u83A:undetectable | 6ectA-1u83A:25.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uqr | 3-DEHYDROQUINATEDEHYDRATASE (Actinobacilluspleuropneumoniae) |
PF01220(DHquinase_II) | 5 | ASN A 8GLY A 131GLY A 128VAL A 99ILE A 72 | None | 1.03A | 6ectA-1uqrA:undetectable | 6ectA-1uqrA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjo | ALANINE--GLYOXYLATEAMINOTRANSFERASE (Nostoc sp. PCC7120) |
PF00266(Aminotran_5) | 5 | GLY A 117GLY A 120ILE A 90VAL A 123ILE A 102 | None | 0.96A | 6ectA-1vjoA:undetectable | 6ectA-1vjoA:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrp | CREATINE KINASE, MCHAIN (Tetronarcecalifornica) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 5 | ASP A 120ILE A 336GLU A 362VAL A 361ILE A 299 | None | 1.00A | 6ectA-1vrpA:undetectable | 6ectA-1vrpA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wr8 | PHOSPHOGLYCOLATEPHOSPHATASE (Pyrococcushorikoshii) |
PF08282(Hydrolase_3) | 5 | GLY A 217GLY A 214ILE A 29VAL A 175ILE A 6 | None | 1.03A | 6ectA-1wr8A:2.1 | 6ectA-1wr8A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ydg | TRP REPRESSORBINDING PROTEIN WRBA (Deinococcusradiodurans) |
PF03358(FMN_red) | 5 | GLY A 29GLY A 33GLU A 35VAL A 36ILE A 9 | None | 1.05A | 6ectA-1ydgA:undetectable | 6ectA-1ydgA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yzg | ADP-RIBOSYLATIONFACTOR-LIKE 8 (Homo sapiens) |
PF00025(Arf) | 5 | LEU A 24GLY A 68VAL A 22LEU A 89ILE A 87 | None | 1.01A | 6ectA-1yzgA:undetectable | 6ectA-1yzgA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bw2 | BYPASS OF FORESPOREC (Bacillussubtilis) |
PF08955(BofC_C)PF08977(BOFC_N) | 5 | ASN A 72GLY A 76GLY A 119GLU A 91ILE A 97 | None | 1.05A | 6ectA-2bw2A:undetectable | 6ectA-2bw2A:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfh | TRAFFICKING PROTEINPARTICLE COMPLEXSUBUNIT 6B (Homo sapiens) |
PF04051(TRAPP) | 6 | LEU C 47GLY C 128GLY C 44SER C 137LEU C 133ILE C 135 | None | 1.42A | 6ectA-2cfhC:undetectable | 6ectA-2cfhC:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d57 | AQUAPORIN-4 (Rattusnorvegicus) |
PF00230(MIP) | 5 | GLY A 146GLY A 144ILE A 223VAL A 53LEU A 133 | None | 0.97A | 6ectA-2d57A:undetectable | 6ectA-2d57A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eyq | TRANSCRIPTION-REPAIRCOUPLING FACTOR (Escherichiacoli) |
PF00270(DEAD)PF00271(Helicase_C)PF02559(CarD_CdnL_TRCF)PF03461(TRCF) | 5 | GLY A 633GLY A 631PHE A 599GLU A 600ILE A 609 | None | 0.99A | 6ectA-2eyqA:2.6 | 6ectA-2eyqA:13.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwf | RING FINGER PROTEIN41 (Homo sapiens) |
PF08941(USP8_interact) | 5 | GLY B 237ILE B 280VAL B 243LEU B 246ILE B 247 | None | 0.92A | 6ectA-2gwfB:undetectable | 6ectA-2gwfB:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h8o | GERANYLTRANSTRANSFERASE (Agrobacteriumfabrum) |
PF00348(polyprenyl_synt) | 5 | LEU A 225GLY A 111ILE A 166VAL A 93ILE A 236 | None | 1.06A | 6ectA-2h8oA:undetectable | 6ectA-2h8oA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3t | TRAFFICKING PROTEINPARTICLE COMPLEXSUBUNIT 6A (Homo sapiens) |
PF04051(TRAPP) | 6 | LEU B 48GLY B 129GLY B 45SER B 138LEU B 134ILE B 136 | None | 1.49A | 6ectA-2j3tB:undetectable | 6ectA-2j3tB:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3t | TRAFFICKING PROTEINPARTICLE COMPLEXSUBUNIT 6A (Homo sapiens) |
PF04051(TRAPP) | 6 | LEU B 48GLY B 129SER B 138GLU B 50LEU B 134ILE B 136 | None | 1.36A | 6ectA-2j3tB:undetectable | 6ectA-2j3tB:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2npn | PUTATIVE COBALAMINSYNTHESIS RELATEDPROTEIN (Corynebacteriumdiphtheriae) |
PF00590(TP_methylase) | 5 | LEU A 214GLY A 204ILE A 240VAL A 226LEU A 229 | None | 1.04A | 6ectA-2npnA:undetectable | 6ectA-2npnA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o01 | PHOTOSYSTEM IREACTION CENTERSUBUNIT XI,CHLOROPLAST (Spinaciaoleracea) |
PF02605(PsaL) | 5 | LEU L 58GLY L 142GLY L 146GLU L 55LEU L 51 | CLA H1501 (-3.8A)NoneNoneCLA L1502 ( 3.4A)None | 0.96A | 6ectA-2o01L:undetectable | 6ectA-2o01L:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p4q | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING 1 (Saccharomycescerevisiae) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | LEU A 73GLY A 100ILE A 97VAL A 80LEU A 83 | None | 0.86A | 6ectA-2p4qA:4.3 | 6ectA-2p4qA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qxt | LIPASE (Bacillussubtilis) |
PF01674(Lipase_2) | 5 | LEU A 124GLY A 172GLY A 175VAL A 100ILE A 128 | None | 0.97A | 6ectA-2qxtA:undetectable | 6ectA-2qxtA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r98 | PUTATIVEACETYLGLUTAMATESYNTHASE (Neisseriagonorrhoeae) |
PF00583(Acetyltransf_1)PF00696(AA_kinase) | 5 | LEU A 259GLY A 278ILE A 281LEU A 241ILE A 242 | None | 1.05A | 6ectA-2r98A:2.6 | 6ectA-2r98A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vt1 | SURFACE PRESENTATIONOF ANTIGENS PROTEINSPAS (Shigellaflexneri) |
PF01312(Bac_export_2) | 5 | ASP B 321GLU B 327VAL B 328LEU B 331ILE B 332 | None | 0.99A | 6ectA-2vt1B:undetectable | 6ectA-2vt1B:14.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zc0 | ALANINE GLYOXYLATETRANSAMINASE (Thermococcuslitoralis) |
PF00155(Aminotran_1_2) | 5 | LEU A 113GLY A 107GLY A 109ILE A 255SER A 246 | NonePMP A 409 (-3.7A)NoneNonePMP A 409 (-3.1A) | 1.04A | 6ectA-2zc0A:undetectable | 6ectA-2zc0A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ajb | PEROXISOMALBIOGENESIS FACTOR 3 (Homo sapiens) |
PF04882(Peroxin-3) | 5 | LEU A 179GLY A 173GLY A 175ILE A 168LEU A 76 | None | 0.98A | 6ectA-3ajbA:undetectable | 6ectA-3ajbA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cer | POSSIBLEEXOPOLYPHOSPHATASE-LIKE PROTEIN (Bifidobacteriumlongum) |
PF02541(Ppx-GppA) | 7 | LEU A 130GLY A 327GLY A 331ASP A 22SER A 324GLU A 159ILE A 229 | NoneNoneNoneSO4 A 346 (-3.0A)NoneSO4 A 344 ( 4.7A)None | 1.44A | 6ectA-3cerA:undetectable | 6ectA-3cerA:24.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3a | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF01301(Glyco_hydro_35) | 5 | GLY A 482GLU A 466VAL A 465LEU A 464ILE A 463 | None | 0.98A | 6ectA-3d3aA:undetectable | 6ectA-3d3aA:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3db2 | PUTATIVENADPH-DEPENDENTOXIDOREDUCTASE (Desulfitobacteriumhafniense) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | GLY A 246GLY A 144PHE A 277GLU A 276LEU A 251 | None | 1.03A | 6ectA-3db2A:3.7 | 6ectA-3db2A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1w | SUGAR ABCTRANSPORTER (Bacillushalodurans) |
PF13407(Peripla_BP_4) | 5 | GLY A 236GLY A 205ASP A 208SER A 257ILE A 255 | None | 0.90A | 6ectA-3g1wA:2.9 | 6ectA-3g1wA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gd8 | AQUAPORIN-4 (Homo sapiens) |
PF00230(MIP) | 5 | LEU A 50GLY A 125GLY A 129PHE A 48LEU A 43 | None | 1.02A | 6ectA-3gd8A:undetectable | 6ectA-3gd8A:23.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h2z | MANNITOL-1-PHOSPHATE5-DEHYDROGENASE (Shigellaflexneri) |
PF01232(Mannitol_dh)PF08125(Mannitol_dh_C) | 5 | GLY A 227GLY A 231GLU A 291VAL A 290ILE A 235 | None | 0.92A | 6ectA-3h2zA:3.7 | 6ectA-3h2zA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hlm | ASPARTATEAMINOTRANSFERASE,MITOCHONDRIAL (Mus musculus) |
PF00155(Aminotran_1_2) | 5 | GLY A 406GLY A 385ILE A 408VAL A 391LEU A 394 | None | 0.99A | 6ectA-3hlmA:undetectable | 6ectA-3hlmA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i3l | ALKYLHALIDASE CMLS (Streptomycesvenezuelae) |
PF04820(Trp_halogenase) | 5 | GLY A 165GLY A 167ILE A 9PHE A 299LEU A 292 | FAD A 600 (-3.6A)NoneFAD A 600 ( 4.9A)NoneNone | 0.97A | 6ectA-3i3lA:2.5 | 6ectA-3i3lA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k3n | PHD FINGER PROTEIN 8 (Homo sapiens) |
PF02373(JmjC) | 5 | GLY A 108GLY A 132ILE A 209VAL A 127ILE A 125 | None | 0.88A | 6ectA-3k3nA:undetectable | 6ectA-3k3nA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l7n | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcusmutans) |
PF00117(GATase) | 5 | GLY A 140ILE A 113VAL A 187LEU A 190ILE A 191 | None | 0.65A | 6ectA-3l7nA:undetectable | 6ectA-3l7nA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3loi | PUTATIVEUNCHARACTERIZEDPROTEIN (Branchiostomabelcheri) |
PF06172(Cupin_5) | 5 | GLY A 128GLU A 11VAL A 12LEU A 15ILE A 16 | None | 0.92A | 6ectA-3loiA:undetectable | 6ectA-3loiA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mgg | METHYLTRANSFERASE (Methanosarcinamazei) |
PF13847(Methyltransf_31) | 5 | GLY A 43GLY A 45ILE A 67GLU A 114VAL A 112 | None | 0.97A | 6ectA-3mggA:14.0 | 6ectA-3mggA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwu | SERINE PROTEASEHTRA1 (Homo sapiens) |
PF13365(Trypsin_2) | 5 | ASN A 290GLY A 206ILE A 282GLU A 231VAL A 184 | None | 0.98A | 6ectA-3nwuA:undetectable | 6ectA-3nwuA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o75 | FRUCTOSE TRANSPORTSYSTEM REPRESSORFRUR (Pseudomonasputida) |
PF00532(Peripla_BP_1) | 6 | LEU A 250GLY A 186PHE A 273VAL A 244LEU A 243ILE A 182 | None | 1.10A | 6ectA-3o75A:3.2 | 6ectA-3o75A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oz6 | MITOGEN-ACTIVATEDPROTEIN KINASE 1,SERINE/THREONINEPROTEIN KINASE (Cryptosporidiumparvum) |
PF00069(Pkinase) | 5 | GLY A 222ASP A 300VAL A 115LEU A 118ILE A 119 | None | 0.97A | 6ectA-3oz6A:undetectable | 6ectA-3oz6A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p3l | CYTOCHROME P450 (Streptomycesthioluteus) |
PF00067(p450) | 5 | LEU A 47GLY A 312VAL A 297LEU A 64ILE A 65 | None | 1.02A | 6ectA-3p3lA:undetectable | 6ectA-3p3lA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pf0 | IMELYSIN-LIKEPROTEIN (Psychrobacterarcticus) |
PF09375(Peptidase_M75) | 5 | GLY A 195GLY A 192VAL A 168LEU A 171ILE A 172 | None | 1.00A | 6ectA-3pf0A:undetectable | 6ectA-3pf0A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pua | PHD FINGER PROTEIN 2 (Homo sapiens) |
PF02373(JmjC) | 5 | GLY A 110GLY A 134ILE A 211VAL A 129ILE A 127 | NoneEDO A 6 (-4.5A)NoneNoneNone | 0.88A | 6ectA-3puaA:undetectable | 6ectA-3puaA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rim | TRANSKETOLASE (Mycobacteriumtuberculosis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | GLY A 245GLU A 238VAL A 237LEU A 265ILE A 263 | None | 1.02A | 6ectA-3rimA:2.6 | 6ectA-3rimA:17.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ruy | ORNITHINEAMINOTRANSFERASE (Bacillusanthracis) |
PF00202(Aminotran_3) | 5 | GLY A 231ASP A 242ILE A 228SER A 50LEU A 257 | NoneNoneLLP A 255 ( 3.9A)NoneNone | 1.05A | 6ectA-3ruyA:undetectable | 6ectA-3ruyA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2g | ZINC-CONTAININGALCOHOLDEHYDROGENASESUPERFAMILY (Cupriaviduspinatubonensis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ASN A 321LEU A 46GLY A 14ASP A 52LEU A 17 | None | 0.89A | 6ectA-3s2gA:5.2 | 6ectA-3s2gA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u78 | LYSINE-SPECIFICDEMETHYLASE 7 (Homo sapiens) |
PF02373(JmjC) | 5 | LEU A 165GLY A 143ILE A 244VAL A 162ILE A 160 | None | 1.03A | 6ectA-3u78A:undetectable | 6ectA-3u78A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wzf | ASPARTATEAMINOTRANSFERASE,CYTOPLASMIC (Homo sapiens) |
PF00155(Aminotran_1_2) | 5 | GLY A 385GLY A 364ILE A 387VAL A 370LEU A 373 | None | 0.98A | 6ectA-3wzfA:2.1 | 6ectA-3wzfA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zbq | PHIKZ039 (Pseudomonasvirus phiKZ) |
no annotation | 5 | GLY A 16GLY A 14ILE A 132GLU A 21ILE A 182 | NoneGDP A 999 (-3.3A)GDP A 999 (-4.1A)NoneNone | 0.96A | 6ectA-3zbqA:undetectable | 6ectA-3zbqA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b98 | BETA-ALANINE--PYRUVATE TRANSAMINASE (Pseudomonasaeruginosa) |
PF00202(Aminotran_3) | 5 | ASN A 285GLY A 160GLY A 155GLU A 122ILE A 128 | NoneNonePXG A 470 (-3.5A)NoneNone | 0.97A | 6ectA-4b98A:undetectable | 6ectA-4b98A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b98 | BETA-ALANINE--PYRUVATE TRANSAMINASE (Pseudomonasaeruginosa) |
PF00202(Aminotran_3) | 5 | ASN A 285GLY A 160GLY A 155ILE A 224GLU A 122 | NoneNonePXG A 470 (-3.5A)NoneNone | 1.05A | 6ectA-4b98A:undetectable | 6ectA-4b98A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cmn | INOSITOLPOLYPHOSPHATE5-PHOSPHATASE OCRL-1 (Homo sapiens) |
PF03372(Exo_endo_phos) | 5 | GLY A 428GLU A 434VAL A 435LEU A 438ILE A 439 | None | 0.98A | 6ectA-4cmnA:undetectable | 6ectA-4cmnA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4io6 | AVGLUR1 LIGANDBINDING DOMAIN (Adineta vaga) |
PF00497(SBP_bac_3) | 5 | GLY A 84ILE A 209VAL A 41LEU A 44ILE A 45 | None | 1.06A | 6ectA-4io6A:undetectable | 6ectA-4io6A:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j1v | MOB KINASE ACTIVATOR1A (Homo sapiens) |
PF03637(Mob1_phocein) | 5 | PHE A 188GLU A 192VAL A 190LEU A 195ILE A 196 | None | 1.05A | 6ectA-4j1vA:undetectable | 6ectA-4j1vA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lry | PTS-DEPENDENTDIHYDROXYACETONEKINASE,DIHYDROXYACETONE-BINDING SUBUNIT DHAK (Escherichiacoli) |
PF02733(Dak1) | 6 | LEU A 79GLY A 52GLY A 75ILE A 86SER A 50ILE A 103 | NoneGOL A 401 (-2.9A)NoneNoneNoneNone | 1.23A | 6ectA-4lryA:undetectable | 6ectA-4lryA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1i | TRANSCRIPTIONALREGULATORY PROTEIN (Mycobacteriumtuberculosis) |
no annotation | 5 | LEU A 63GLY A 57GLY A 59VAL A 48LEU A 7 | None | 1.03A | 6ectA-4o1iA:undetectable | 6ectA-4o1iA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1m | ENOYL-ACYL CARRIERREDUCTASE (Toxoplasmagondii) |
PF13561(adh_short_C2) | 5 | LEU A 128GLY A 16VAL A 125LEU A 124ILE A 123 | NAD A 401 (-4.0A)NAD A 401 (-3.9A)NoneNoneNone | 0.99A | 6ectA-4o1mA:4.8 | 6ectA-4o1mA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o5p | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF09994(DUF2235) | 5 | LEU A 332GLY A 233VAL A 90LEU A 93ILE A 94 | None | 1.03A | 6ectA-4o5pA:undetectable | 6ectA-4o5pA:16.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4omb | PHOSPHATE BINDINGPROTEIN (Pseudomonasaeruginosa) |
PF12849(PBP_like_2) | 5 | ASN A 133GLY A 163ILE A 135VAL A 176ILE A 225 | None | 0.97A | 6ectA-4ombA:undetectable | 6ectA-4ombA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pg6 | HOMOSERINEDEHYDROGENASE (Staphylococcusaureus) |
PF00742(Homoserine_dh)PF03447(NAD_binding_3) | 5 | GLY A 307ILE A 22VAL A 77LEU A 8ILE A 6 | None | 1.03A | 6ectA-4pg6A:3.8 | 6ectA-4pg6A:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pqj | PHOSPHATE BINDINGPROTEIN (Pseudomonasaeruginosa) |
PF12849(PBP_like_2) | 5 | ASN A 133GLY A 163ILE A 135VAL A 176ILE A 225 | None | 0.97A | 6ectA-4pqjA:undetectable | 6ectA-4pqjA:23.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9n | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Chlamydiatrachomatis) |
PF13561(adh_short_C2) | 5 | LEU A 127GLY A 15VAL A 124LEU A 123ILE A 122 | NAI A 301 (-3.8A)NAI A 301 ( 4.3A)NoneNoneNone | 0.93A | 6ectA-4q9nA:4.3 | 6ectA-4q9nA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rl3 | CHITINASE A (Pterisryukyuensis) |
PF00704(Glyco_hydro_18) | 5 | GLY A 333PHE A 305VAL A 303LEU A 302ILE A 300 | None | 1.03A | 6ectA-4rl3A:undetectable | 6ectA-4rl3A:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rzh | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Synechocystissp. PCC 6803) |
PF13561(adh_short_C2) | 5 | GLY A 118GLU A 70VAL A 71LEU A 74ILE A 75 | None | 0.92A | 6ectA-4rzhA:5.9 | 6ectA-4rzhA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uhm | OMEGA AMINOACID-PYRUVATEAMINOTRANSFERASE (Pseudomonas sp.) |
PF00202(Aminotran_3) | 5 | ASN A 285GLY A 160GLY A 155GLU A 122ILE A 128 | NoneNonePLP A1458 (-3.5A)NoneNone | 1.00A | 6ectA-4uhmA:undetectable | 6ectA-4uhmA:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x6k | ANHYDROSIALIDASE ([Ruminococcus]gnavus) |
PF13088(BNR_2) | 5 | LEU A 705GLY A 279ASP A 319SER A 285ILE A 287 | None | 1.05A | 6ectA-4x6kA:undetectable | 6ectA-4x6kA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zas | CALS13 (Micromonosporaechinospora) |
PF01041(DegT_DnrJ_EryC1) | 5 | ASN A 254GLY A 209PHE A 211GLU A 44ILE A 260 | None | 1.06A | 6ectA-4zasA:2.1 | 6ectA-4zasA:25.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by7 | 3-OXOACYL-ACPSYNTHASE III (Verrucosisporamaris) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 5 | LEU A 247GLY A 316GLY A 304VAL A 108LEU A 111 | None | 1.00A | 6ectA-5by7A:undetectable | 6ectA-5by7A:27.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d2e | MLNE (Bacillusvelezensis) |
PF08659(KR) | 5 | GLY A 387ILE A 357GLU A 339LEU A 343ILE A 344 | NoneNonePG4 A 603 (-3.9A)PG4 A 603 ( 4.5A)None | 1.06A | 6ectA-5d2eA:3.2 | 6ectA-5d2eA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9j | MRNA CAP GUANINE-N7METHYLTRANSFERASE,MRNA CAP GUANINE-N7METHYLTRANSFERASE (Homo sapiens) |
PF03291(Pox_MCEL) | 6 | GLY A 205GLY A 207ASP A 211ILE A 228SER A 262VAL A 286 | SAH A 501 (-3.4A)SAH A 501 (-3.4A)SAH A 501 ( 4.1A)SAH A 501 (-3.8A)SAH A 501 (-4.0A)SAH A 501 (-4.2A) | 0.60A | 6ectA-5e9jA:14.3 | 6ectA-5e9jA:24.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9w | MRNA CAP GUANINE-N7METHYLTRANSFERASE (Homo sapiens) |
PF03291(Pox_MCEL) | 6 | GLY A 205GLY A 207ASP A 211ILE A 228SER A 262VAL A 286 | SAH A 500 (-3.8A)SAH A 500 (-3.5A)SAH A 500 ( 4.0A)SAH A 500 (-3.7A)SAH A 500 (-4.1A)SAH A 500 (-3.8A) | 0.57A | 6ectA-5e9wA:14.5 | 6ectA-5e9wA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5evj | ARSENITEMETHYLTRANSFERASE (Chlamydomonasreinhardtii) |
PF13847(Methyltransf_31) | 5 | GLY A 91GLY A 93ASP A 97VAL A 171LEU A 174 | None | 0.90A | 6ectA-5evjA:14.0 | 6ectA-5evjA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gai | TAIL FIBER PROTEIN (Salmonellavirus P22) |
no annotation | 5 | GLY Y 441GLY Y 463ILE Y 454VAL Y 434LEU Y 433 | None | 1.00A | 6ectA-5gaiY:undetectable | 6ectA-5gaiY:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT DELTA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 5 | LEU d 308ILE d 241VAL d 312LEU d 286ILE d 288 | None | 1.05A | 6ectA-5gw5d:undetectable | 6ectA-5gw5d:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ASN A1561GLY A1621ILE A1557GLU A1311LEU A1602 | None | 1.06A | 6ectA-5i8iA:undetectable | 6ectA-5i8iA:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jyd | SHORT CHAINDEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | GLY A 80GLU A 110VAL A 111LEU A 114ILE A 115 | NAD A 901 (-3.0A)IOD A 908 ( 4.4A)NoneNoneNone | 0.77A | 6ectA-5jydA:4.8 | 6ectA-5jydA:23.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8d | COAGULATION FACTORVIII,IG GAMMA-1CHAIN C REGION (Homo sapiens) |
PF00754(F5_F8_type_C)PF07731(Cu-oxidase_2) | 6 | LEU B1756GLY B1853GLY B1760ILE B1763PHE B1879LEU B1856 | None | 1.29A | 6ectA-5k8dB:undetectable | 6ectA-5k8dB:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kxj | L-ASPARTATE OXIDASE (Salmonellaenterica) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | GLY A 222GLY A 224VAL A 496LEU A 499ILE A 500 | None | 0.83A | 6ectA-5kxjA:undetectable | 6ectA-5kxjA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ncr | TYROSINE PHOSPHATASE (Orf virus) |
PF00782(DSPc) | 5 | LEU A 162GLY A 115GLY A 120ASP A 81GLU A 163 | NonePO4 A 200 (-3.4A)NonePO4 A 200 (-3.8A)None | 1.06A | 6ectA-5ncrA:undetectable | 6ectA-5ncrA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5osh | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 29 (Homo sapiens) |
no annotation | 5 | LEU A 40GLY A 61GLY A 38PHE A 63GLU A 65 | None | 0.95A | 6ectA-5oshA:undetectable | 6ectA-5oshA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tnu | DNA-DEPENDENT ATPASEXPBII (Sulfurisphaeratokodaii) |
no annotation | 5 | LEU A 199PHE A 173VAL A 115LEU A 120ILE A 121 | None | 1.04A | 6ectA-5tnuA:3.4 | 6ectA-5tnuA:24.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uc5 | CHS2 CHALCONESYNTHASE (Malus domestica) |
no annotation | 5 | LEU A 268ASP A 207VAL A 271LEU A 274ILE A 275 | None | 1.05A | 6ectA-5uc5A:undetectable | 6ectA-5uc5A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5whs | CATALASE-PEROXIDASE (Neurosporacrassa) |
no annotation | 5 | LEU A 148GLY A 106GLY A 108ASP A 172LEU A 424 | None | 1.06A | 6ectA-5whsA:undetectable | 6ectA-5whsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ya1 | AUTOINDUCER-2 KINASE (Escherichiacoli) |
no annotation | 5 | LEU A 272GLY A 429GLY A 427ILE A 449LEU A 439 | HEZ A 703 ( 4.3A)ATP A 701 ( 3.8A)NoneNoneNone | 1.02A | 6ectA-5ya1A:undetectable | 6ectA-5ya1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yk2 | PROBABLE CONSERVEDATP-BINDING PROTEINABC TRANSPORTER (Mycobacteriumtuberculosis) |
no annotation | 5 | LEU A 422GLY A 266ILE A 428VAL A 415ILE A 412 | None | 1.07A | 6ectA-5yk2A:undetectable | 6ectA-5yk2A:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ypt | STILBENECARBOXYLATESYNTHASE 1 (Marchantiapolymorpha) |
no annotation | 5 | LEU A 270ASP A 209VAL A 273LEU A 276ILE A 277 | None | 1.04A | 6ectA-5yptA:undetectable | 6ectA-5yptA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6blj | SERINE-TRNA LIGASE (Naegleriafowleri) |
no annotation | 5 | LEU A 140GLY A 143ILE A 18SER A 21LEU A 31 | None | 1.05A | 6ectA-6bljA:undetectable | 6ectA-6bljA:undetectable |